- Fellowship - Warren Grant Magnuson Clinical Center - NIH (2002-2003), Nuclear Medicine
- Residency - Hartford Hospital (2000-2002), Anatomic Pathology
- Residency - University of Connecticut Health Center (1998-2000), Nuclear Medicine
- Residency - SUNY Upstate Medical University (1996-1998), Pathology
- Fellowship - Ball Memorial Hospital (1995-1996), Hematopathology
- Graduate School - University of South Florida (1992-1994), Medical Microbiology & Immunology
- Medical School - Jiangxi Medical College (1978-1982)
Fangyu Peng, M.D., Ph.D.
- Radiology - Nuclear Medicine
Fangyu Peng, M.D., is an Associate Professor of Radiology at UT Southwestern Medical Center and a member of its Nuclear Medicine Division. He also serves as the Director of Positron Emission Tomography (PET) Translational Imaging, and holds a secondary appointment in the Advanced Imaging Research Center. His clinical interests include general nuclear medicine, PET imaging, and computed tomography (CT), with a particular interest in oncology and neurology.
Dr. Peng earned his medical degree at Jiangxi Medical College in Nanchang, China. He then earned a master’s degree in molecular virology at Chinese Academy of Preventive Medicine's Institute of Virology in Beijing. He earned a doctoral degree in microbiology and immunology at the University of South Florida College of Medicine in Tampa. He then completed a research fellowship program in hematopathology at Ball Memorial Hospital in Muncie, Indiana, before completing his residency in pathology at Upstate Medical University in Syracuse, New York. Dr. Peng then completed a residency in nuclear medicine at the University of Connecticut Health Center in Farmington, and in anatomic pathology at Hartford Hospital. He completed his formal training with a fellowship program in nuclear medicine and molecular imaging at the National Institutes of Health in Bethesda, Maryland.
Before being recruited in 2008 to enhance the Nuclear Medicine Division's translational research, Dr. Peng served as an Assistant Professor of Radiology and Pediatrics at Wayne State University School of Medicine in Detroit.
At UT Southwestern, he troubleshoots and improves imaging protocols, and actively participates in educational endeavors, in addition to his regular clinical responsibilities.
Dr. Peng focuses his research on inherited and acquired copper metabolism disorders in Wilson’s disease, Alzheimer’s disease, and traumatic brain injury, and investigates copper metabolism as a theranostic target for molecular imaging and cancer treatment. His research has been published in more than 50 peer-reviewed publications. He also invented and received a patent for intracellular trapping of radionuclides by enzyme-mediated reduction.
A career marked by service
Dr. Peng is a member of the Nuclear Medicine Residency Program Committee, the Nuclear Medicine Division Research Committee, and the Clinical Competency Committee of the Nuclear Medicine Residency Program, which he chairs. He also serves the Society of Nuclear Medicine and Molecular Imaging as a member of the Brain Imaging Council and the Radiopharmaceutical Sciences Council, and the American College of Medicine as a member of the International Affairs Committee.
He is an active member of numerous professional societies, including the International Society for Neurochemistry, the International Society to Advance Alzheimer's Research and Treatment, and the American Society for Neurochemistry.
Robust editorial and lecture activity
In addition to his publishing endeavors, Dr. Peng also serves on the editorial board of several academic journals, including the Journal of Radiology and Radiation Therapy, American Journal of Nuclear Medicine and Molecular Imaging, Chinese Journal of Nuclear Medicine and Molecular Imaging, and the Journal of Alzheimer's Disease. He is frequently an invited lecturer at medical institutions, academic research centers, and professional organizations throughout the country and world.
- Society of Nuclear Medicine and Molecular Imaging (1998)
- American College of Nuclear Medicine (2014)
- International Society for Neurochemistry (2015)
- International Society to Advance Alzheimers Research and Treatment (2016)
- American Society of Neurochemistry (2017)
- Chief Resident in Nuclear Medicine 1999-2000, University of Connecticut Health Center
- Fellow 2019, American College of Nuclear Medicine
Imaging Copper Metabolism Imbalance in Atp7b (-/-) Knockout Mouse Model of Wilson's Disease with PET-CT and Orally Administered (64)CuCl (2).
Peng F, Lutsenko S, Sun X, Muzik O Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2011 Dec
Alteration of Copper Fluxes in Brain Aging: A Longitudinal Study in Rodent Using 64CuCl2-PET/CT.
Peng F, Xie F, Muzik O Aging and disease 2018 Feb 9 1 109-118
Age-dependent changes of cerebral copper metabolism in Atp7b (-/-) knockout mouse model of Wilson's disease by [(64)Cu]CuCl2-PET/CT.
Xie F, Xi Y, Pascual JM, Muzik O, Peng F Metabolic brain disease 2017 Jan
Asymmetric radiotracer activity of enlarged cerebral spinal fluid space on radionuclide cisternography with SPET/CT.
Bulman JC, Wachsmann J, Peng F Hellenic journal of nuclear medicine 2016 Nov
Immune-mediated Disease in Ipilimumab Immunotherapy of Melanoma with FDG PET-CT.
Wachsmann JW, Ganti R, Peng F Academic radiology 2016 Nov
Molecular imaging and therapy targeting copper metabolism in hepatocellular carcinoma.
Wachsmann J, Peng F World journal of gastroenterology 2016 Jan 22 1 221-31
Detection of Widespread Metastasis in a Case of Aggressive Carcinoma Showing Thymuslike Differentiation (CASTLE Disease) Using 18F-FDG PET/CT.
Iyamu I, Wachsmann J, Truelson J, Mathews D, Peng F Clinical nuclear medicine 2015 Apr
Reduced 64Cu Uptake and Tumor Growth Inhibition by Knockdown of Human Copper Transporter 1 in Xenograft Mouse Model of Prostate Cancer.
Cai H, Wu JS, Muzik O, Hsieh JT, Lee RJ, Peng F Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2014 Mar
Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells.
Cai H, Peng F Oncology reports 2013 Apr
Positron emission tomography of copper metabolism in the Atp7b?/? knock-out mouse model of Wilson's disease.
Peng F, Lutsenko S, Sun X, Muzik O Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2012 Feb 14 1 70-8
Assessment of progression and treatment response of optic pathway glioma with positron emission tomography using alpha-[(11)C]methyl-L-tryptophan.
Peng F, Juhasz C, Bhambhani K, Wu D, Chugani DC, Chugani HT Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2007 May-Jun 9 3 106-9
Positron Emission Tomography of Human Hepatocellular Carcinoma Xenografts in Mice Using Copper (II)-64 Chloride as a Tracer with Copper (II)-64 Chloride.
Zhang H, Cai H, Lu X, Muzik O, Peng F Academic radiology 2011 Dec 18 12 1561-8
Use of 2-deoxy-2-[F-18]-fluoro-D-glucose positron emission tomography to monitor therapeutic response by rhabdomyosarcoma in children: report of a retrospective case study.
Peng F, Rabkin G, Muzik O Clinical nuclear medicine 2006 Jul 31 7 394-7
Mouse extrahepatic hepatoma detected on MicroPET using copper (II)-64 chloride uptake mediated by endogenous mouse copper transporter 1.
Peng F, Liu J, Wu JS, Lu X, Muzik O Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2005 Sep-Oct 7 5 325-9
Radiopharmaceuticals for Assessment of Altered Metabolism and Biometal Fluxes in Brain Aging and Alzheimer's Disease with Positron Emission Tomography.
Xie F, Peng F Journal of Alzheimer's disease : JAD 2017 Jun
Detection of Increased 64Cu uptake in Traumatic Brain Injury with 64CuCl2-PET/CT.
Peng F, Muzik O, Gatson J, Kernie S, Diaz-Arrastia R Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2015 Jun
Ectopic Thyroid Tissue in the Mediastinum Characterized by Histology and Functional Imaging with I-123 SPECT/CT.
Hummel J, Wachsmann J, Carrick K, Oz OK, Mathews D, Peng F Case reports in radiology 2017 2017 9084207
Positron emission tomography for measurement of copper fluxes in live organisms.
Peng F Annals of the New York Academy of Sciences 2014 Mar
PET of human prostate cancer xenografts in mice with increased uptake of 64CuCl2.
Peng F, Lu X, Janisse J, Muzik O, Shields AF Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006 Oct 47 10 1649-52
- Imaging Copper Metabolism Imbalance in Atp7b (-/-) Knockout Mouse Model of Wilson's Disease with PET-CT and Orally Administered (64)CuCl (2).
- Targeting copper metabolism for molecular cancer imaging and therapy
- Metabolic imaging of copper metabolism imbalance in Wilson's disease, Alzheimer's disease, and traumatic brain injury