- Medical School - Washington University School of Medicine
- Internship - Jewish Hospital of St. Louis (1988-1989), Internal Medicine
- Residency - Barnes-Jewish Hospital (1989-1992), Neurology
- Fellowship - Washington University in St. Louis (1992-1994), Neuromuscular Disease
Jeffrey Elliott, M.D.
Neuromuscular Disorders
- Neurology
- Neuromuscular Diseases
- Amyotrophic Lateral Sclerosis (ALS)
Biography
Jeffrey Elliott, M.D., is a Professor in the Department of Neurology at UT Southwestern Medical Center. He specializes in neuromuscular disease, with a special interest in amyotrophic lateral sclerosis (ALS) and genetic neuromuscular disorders.
Dr. Elliott earned his medical degree at Washington University in St. Louis, Missouri, where he also completed a residency in neurology and a fellowship in neuromuscular disease.
Certified by the American Board of Psychiatry and Neurology, he joined the UT Southwestern faculty in 1997.
Dr. Elliott is Director of the MDA/ALS Clinic at UT Southwestern Medical Center and is a member of the American Academy of Neurology, the American Neurological Association, and the American Association of Neuromuscular and Electrodiagnostic Medicine.
He serves as an ad-hoc reviewer for several scholarly journals and has delivered numerous presentations, contributed to several books, and published many peer-reviewed academic articles related to his areas of expertise.
Education & Training
Professional Associations & Affiliations
- American Academy of Neurology
- American Neurological Association
- American Association of Neuromuscular and Electrodiagnostic Medicine
Honors & Awards
- Trephined Cranium Award for Excellence in Neurology Teaching 2018, UT Southwestern
- President’s Research Council Distinguished Young Researcher Award 1998, UT Southwestern
- Jacques J. Bronfenbrenner Award in Infectious Disease 1988, Washington University in St. Louis
- Robert Carter Medical School Prize 1985, Washington University in St. Louis
Books & Publications
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Books
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A 63-year-old man with nausea, vomiting and orthostatic dizziness and distal limb paresthesia in A Case-Based Guide to Neuromuscular Pathology
Elliott JL, Zhou L, Cai C, Kaku M (2019), Springer -
ALS and the copper chaperone CCS in Protein Chaperones and Protein from Neurodegenerative Disease
Elliott JL, Son M (2011)
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A 63-year-old man with nausea, vomiting and orthostatic dizziness and distal limb paresthesia in A Case-Based Guide to Neuromuscular Pathology
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Publications
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A novel heterozygous mutation in the C-terminal region of HSPB8 leads to limb-girdle rimmed vacuolar myopathy
Nicolau S, Liewluck T, Elliott JL, Engel AG, Milone M Neuromuscular Disorders 2020 Mar 30 236-240 -
Gradually progressive spastic ataxia in a young man steadily unsteady
Dubey D, Khemani P, Remster E, Elliott JL JAMA Neurology 2017 Feb 74 238-241 -
Association between dietary intake and function in amyotrophic lateral sclerosis
Nieves JW, Gennings C, Factor-Litvak P, Hupf J, Singleton J, Sharf V, Oskarsson B, Filho JA, Sorenson EJ, D'Amico E, Goetz R, Mitsumoto H, Singleton J, Beck CC, Merle D, Shah T, Kim MP, Lee YW, Christodoulou G, Dalton K, Kidd J, Gilbert E, Kilty M, Heitzman D, Rodriguez W, Hand S, Washington M, Spears B, Burson B, Bedlack RS, Grace K, Boyette C, Katz JS, Miller RG, Forshew D, Beemsterboer J, Harris W, McCoy S, Zayas-Bazan T, Saephanh C, Barohn RJ, McVey AL, Dimachkie MM, Pasnoor M, Wang Y, Walsh M, Herbelin L, Miller J, Anderson K, Klingerman S, Weis D, Joyce N, Lim S, Cregan M, Kasarskis EJ, Vanderpool K, Taylor D, Thomas S, King J, Wells R, Lomen-Hoerth C, Murphy J, Duong YN, Robins D, Villerme C, Rollins YD, Ringel SP, Quan D, Whitethorn E, Mozaffar T, Wang AK, Martin V, Minton B, Tully P, Davis D, Thaisetthawatkul P, Cowardin C, Herstein R, Swenson AJ, Jimmeh-Fletcher D, Olalde H, Sieren J, Nations SP, Elliott J, Trivedi J, Gorham N, Shefner JM, Watson ML, Moore J, Markis K, Grosso M, Andrews JA, Koczon-Jaremko A, Bowen J JAMA neurology 2016 Dec 73 1425-1432 -
Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SODG93A mice co-expressing the Copper-Chaperone-for-SOD
Williams JR, Trias E, Beilby PR, Lopez NI, Labut EM, Bradford CS, Roberts BR, McAllum EJ, Crouch PJ, Rhoads TW, Pereira C, Son M, Elliott JL, Franco MC, Estévez AG, Barbeito L, Beckman JS Neurobiology of Disease 2016 May 89 1-9 -
The RNA-binding protein TDP-43 selectively disrupts MicroRNA-1/206 incorporation into the RNA-induced silencing complex
King IN, Yartseva V, Salas D, Kumar A, Heidersbach A, Ando DM, Stallings NR, Elliott JL, Srivastava D, Ivey KN Journal of Biological Chemistry 2014 May 289 14263-14271 -
Mitochondrial defects in transgenic mice expressing Cu,Zn Superoxide Dismutase mutations, the role of Copper Chaperone for SOD1
Son M, Elliott JL Journal of the Neurological Sciences 2014 Jan 336 1-7 -
TDP-43, an ALS Linked Protein, Regulates Fat Deposition and Glucose Homeostasis
Stallings NR, Puttaparthi K, Dowling KJ, Luther CM, Burns DK, Davis K, Elliott JL PloS one 2013 Aug 8 -
Biochemical properties and in vivo effects of the SOD1 zinc-binding site mutant (H80G)
Son M, Srikanth U, Puttaparthi K, Luther C, Elliott JL Journal of Neurochemistry 2011 Sep 118 891-901 -
ALS and the Copper Chaperone CCS
Son M, Elliott JL 2011 Jun 315-357 -
Huntington chorea presenting with motor neuron disease
Sadeghian H, O'Suilleabhain PE, Battiste J, Elliott JL, Trivedi JR Archives of neurology 2011 May 68 650-652 -
Progressive motor weakness in transgenic mice expressing human TDP-43
Stallings NR, Puttaparthi K, Luther CM, Burns DK, Elliott JL Neurobiology of Disease 2010 Nov 40 404-414 -
Deep brain stimulation artifact in needle electromyography
Sadeghian H, Chitnis S, Elliott JL Archives of neurology 2010 Aug 67 1030 -
Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling
Hu W, Nessler S, Hemmer B, Eagar TN, Kane LP, Leliveld SR, Müller-Schiffmann A, Gocke AR, Lovett-Racke A, Ben LH, Hussain RZ, Breil A, Elliott JL, Puttaparthi K, Cravens PD, Singh MP, Petsch B, Stitz L, Racke MK, Korth C, Stüve O Brain 2010 Feb 133 375-388 -
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice
Williams AH, Valdez G, Moresi V, Qi X, McAnally J, Elliott JL, Bassel-Duby R, Sanes JR, Olson EN Science 2009 Dec 326 1549-1554 -
Redox susceptibility of SOD1 mutants is associated with the differential response to CCS over-expression in vivo
Son M, Fu Q, Puttaparthi K, Matthews CM, Elliott JL Neurobiology of Disease 2009 Apr 34 155-162 -
Biological effects of CCS in the absence of SOD1 enzyme activation: Implications for disease in a mouse model for ALS
Proescher JB, Son M, Elliott JL, Culotta VC Human molecular genetics 2008 Jun 17 1728-1737 -
Isolated cytochrome C oxidase deficiency in G93A SOD1 mice overexpressing CCS protein
Son M, Leary SC, Romain N, Pierrel F, Winge DR, Haller RG, Elliott JL Journal of Biological Chemistry 2008 May 283 12267-12275 -
The death domain-containing kinase RIP1 regulates p27Kip1 levels through the PI3K-Akt-forkhead pathway
Park S, Ramnarain DB, Hatanpaa KJ, Mickey BE, Saha D, Paulmurugan R, Madden CJ, Wright PS, Bhai S, Ali MA, Puttaparthi K, Hu W, Elliott JL, Stuve O, Habib AA EMBO Reports 2008 9 766-773 -
Assessing the role of immuno-proteasomes in a mouse model of familial ALS
Puttaparthi K, Van Kaer L, Elliott JL Experimental Neurology 2007 Jul 206 53-58 -
Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology
Son M, Puttaparthi K, Kawamata H, Rajendran B, Boyer PJ, Manfredi G, Elliott JL Proceedings of the National Academy of Sciences of the United States of America 2007 Apr 104 6072-6077 -
Novel mutations that enhance or repress the aggregation potential of SOD1
Krishnan U, Son M, Rajendran B, Elliott JL Molecular and Cellular Biochemistry 2006 Jul 287 201-211 -
Non-neuronal induction of immunoproteasome subunits in an ALS model: Possible mediation by cytokines
Puttaparthi K, Elliott JL Experimental Neurology 2005 Dec 196 441-451 -
Beginning to understand hereditary spastic paraplegia atlastin
Elliott JL Archives of neurology 2004 Dec 61 1842-1843 -
Western ALS study group
Miller RG, Moore DH, Jackson CE, Gelinas D, Barohn RJ, McVey A, Dick A, Saperstein D, Rosenfeld J, Bromberg M, Petajan J, Ravits J, Kasarskis E, Neville H, Ringel S, Quan D, Mandler R, Bosch EP, Smith B, Ross M, Graves M, Genge A, Lomen-Hoerth C, Olney RK, Pestronk A, Gordon PH, Walk D, Day J, Parry G, Lou JS, Eisen A, Miller TM, Cwik V, McCluskey L, Elman L, Kclkar P, Bertorini T, McGrath MS, Elliott J, Tennore R, Festoff BW, Beckman JS, Flax J, Stephan D Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 2004 Sep 5 121-124 -
Aggregate formation in the spinal cord of mutant SOD1 transgenic mice is reversible and mediated by proteasomes
Puttaparthi K, Wojcik C, Rajendran B, DeMartino GN, Elliott JL Journal of Neurochemistry 2003 Nov 87 851-860 -
Aggregate formation in Cu,Zn superoxide dismutase-related proteins
Son M, Cloyd CD, Rothstein JD, Rajendran B, Elliott JL Journal of Biological Chemistry 2003 Apr 278 14331-14336 -
Erratum: "Disease progression in a transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins (Journal of Neuroscience (October 15, 2002) (8790-8796))
Puttaparthi K, Gitomer WL, Krishnan U, Son M, Rajendran B, Elliott JL Journal of Neuroscience 2003 Jan 23 I -
Disease progression in a transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins
Puttaparthi K, Gitomer WL, Krishnan U, Son M, Rajendran B, Elliott JL Journal of Neuroscience 2002 Oct 22 8790-8796 -
Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis
Elliott JL Molecular Brain Research 2001 Nov 95 172-178 -
Survival in a transgenic model of FALS is independent of iNOS expression [1]
Son M, Fathallah-Shaykh HM, Elliott JL Annals of Neurology 2001 50 273 -
Zinc and copper in the pathogenesis of amyotrophic lateral sclerosis
Elliott JL Progress in Neuro-Psychopharmacology and Biological Psychiatry 2001 25 1169-1185 -
Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls
Honig LS, Chambliss DD, Bigio EH, Carroll SL, Elliott JL Neurology 2000 Oct 55 1082-1088 -
Metallothionein expression is altered in a transgenic murine model of familial amyotrophic lateral sclerosis
Gong YH, Elliott JL Experimental Neurology 2000 Mar 162 27-36 -
Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration
Gong YH, Parsadanian AS, Andreeva A, Snider WD, Elliott JL Journal of Neuroscience 2000 Jan 20 660-665 -
Experimental models of amyotrophic lateral sclerosis
Elliott JL Neurobiology of Disease 1999 Oct 6 310-320 -
Brachial amyotrophic diplegia: A slowly progressive motor neuron disorder
Katz JS, Wolfe GI, Andersson PB, Saperstein DS, Elliott JL, Nations SP, Bryan WW, Barohn RJ Neurology 1999 Sep 53 1071-1076 -
Mutation analysis in Emery-Dreifuss muscular dystrophy
Nevo Y, Al-Lozi M, Parsadanian AS, Elliott JL, Connolly AM, Pestronk A Pediatric Neurology 1999 Jul 21 456-459 -
A clearer view of upper motor neuron dysfunction in amyotrophic lateral sclerosis
Elliott JL Archives of neurology 1998 55 910-912 -
Hereditary motor and sensory neuropathy IIB: Clinical and electrodiagnostic characteristics
Elliott JL, Kwon JM, Goodfellow PJ, Yee WC Neurology 1997 Jan 48 23-28 -
Motor neuron growth factors
Elliott JL, Snider WD Neurology 1996 Oct 47 S47-S53 -
BAX is required for neuronal death after trophic factor deprivation and during development
Deckwerth TL, Elliott JL, Knudson CM, Johnson EM, Snider WD, Korsmeyer SJ Neuron 1996 Sep 17 401-411 -
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
Reaume AG, Elliott JL, Hoffman EK, Kowall NW, Ferrante RJ, Siwek DF, Wilcox HM, Flood DG, Beal MF, Brown RH, Scott RW, Snider WD Nature genetics 1996 May 13 43-47 -
Misclassification and linkage of hereditary sensory and autonomic neuropathy type 1 as Charcot-Marie-Tooth disease, type 2B [4]
Vance JM, Speer MC, Stajich JM, West S, Wolpert C, Gaskell P, Lennon F, Tim RM, Rozear M, Othmane KB, Pericak-Vance MA, Yee WC, Elliott JL, Kwon JM, Goodfellow P American Journal of Human Genetics 1996 59 258-262 -
Parvalbumin is a marker of ALS-resistant motor neurons
Elliott JL, Snider WD NeuroReport 1995 Feb 6 449-452 -
Assignment of a second Charcot-Marie-Tooth type II locus to chromosome 3q
Kwon JM, Elliott JL, Yee WC, Ivanovich J, Scavarda NJ, Moolsintong PJ, Goodfellow PJ American Journal of Human Genetics 1995 57 853-858 -
Distal lower motor neuron syndrome with high-titer serum IgM anti–GM1 antibodies: Improvement following immunotherapy with monthly plasma exchange and intravenous cyclophosphamide
Pestronk A, Lopate G, Kornberg AJ, Elliott JL, Blume G, Yee WC, Goodnough LT Neurology 1994 Nov 44 2028-2031 -
Progression of multifocal motor neuropathy during apparently successful treatment with human immunoglobulin
Elliott JL, Pestronk A Neurology 1994 May 44 967-968 -
Upregulation of nmdari mrna induced by mk-801 is associated with massive death of axotomized motor neurones in adult rats
Sanner C, Elliott JL, Snider WD Neurobiology of Disease 1994 1 121-129 -
Influences of neurotrophins on mammalian motoneurons in vivo
Yan Q, Elliott JL, Matheson C, Sun J, Zhang L, Mu X, Rex KL, Snider WD Journal of Neurobiology 1993 Dec 24 1555-1577 -
Axotomy‐induced neuronal death during development
Snider WD, Elliott JL, Yan Q Journal of Neurobiology 1992 Nov 23 1231-1246 -
Selective dependence of mammalian dorsal root ganglion neurons on nerve growth factor during embryonic development
Ruit KG, Elliott JL, Osborne PA, Yan Q, Snider WD Neuron 1992 Mar 8 573-587 -
Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
Yan Q, Elliott J, Snider WD Nature 1992 360 753-755
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A novel heterozygous mutation in the C-terminal region of HSPB8 leads to limb-girdle rimmed vacuolar myopathy
Research
- Amyotrophic lateral sclerosis
- Energetics
Clinical Focus
- Neuromuscular Diseases
- Amyotrophic Lateral Sclerosis (ALS)
- Genetic Neuromuscular Disorders
Results: 1 Locations
Neurology Clinic - Neuromuscular Disorders
at James W. Aston Ambulatory Care Center 5303 Harry Hines Blvd., 8th FloorDallas, Texas 75390 214-645-8800 Monday-Friday: 7 a.m. to 6 p.m. Directions to Neurology Clinic - Neuromuscular Disorders Parking Info for Neurology Clinic - Neuromuscular Disorders