Jennifer Cuthbert, M.D.

Distinguished Teaching Professor

Internal Medicine - Digestive and Liver Diseases

Biography

Dr. Cuthbert obtained her medical degree (M.B.B.S.) from the University of Sydney (1973) and undertook internship, residency in medicine and one year of Gastroenterology training at teaching hospitals of the University of Sydney (1973-1976). Between 1977 and 1981, she completed a clinical research fellowship in hepatology and a basic research fellowship in immunology in the Department of Internal Medicine at UT Southwestern. In 1992, Dr. Cuthbert was awarded the M.D. from the University of Sydney for a thesis entitled "The Role of Lipid Metabolism in Human T Lymphocyte Proliferation".

Education & Training

Undergraduate - University of Sydney, Medicine
Medical School - University of Sydney, Medicine

Professional Associations & Affiliations

American Association for the Study of Liver Disease

Honors & Awards

Distinguished Clinical Science Educator 2015
Fellow of the American Association for the Study of Liver Diseases 2014
D Magazine - Best Doctor 2008-2015, 1999, 2005
Distinguished Teaching Professor 2006
Southwestern Academy of Teachers 2006, Founding member
UT Academy of Health Science Education 2005, Founding member

Books & Publications

Publications
- Alcoholic Hepatitis: Risk Factors, Pathogenesis, and Approach to Treatment.
  Yeluru A, Cuthbert JA, Casey L, Mitchell MC Alcoholism, clinical and experimental research 2016 Feb 40 2 246-55
- Lactulose vs Polyethylene Glycol 3350-Electrolyte Solution for Treatment of Overt Hepatic Encephalopathy: The HELP Randomized Clinical Trial.
  Rahimi RS, Singal AG, Cuthbert JA, Rockey DC JAMA internal medicine 2014 Sep
- Elevated ammonia concentrations: Potential for pre-analytical and analytical contributing factors.
  Hashim IA, Cuthbert JA Clinical biochemistry 2014 Aug
- Establishing, harmonizing and analyzing critical values in a large academic health center.
  Hashim IA, Cuthbert JA Clinical chemistry and laboratory medicine : CCLM / FESCC 2014 Mar
- Predicting Short-Term Mortality and Long-Term Survival for Hospitalized US Patients with Alcoholic Hepatitis.
  Cuthbert JA, Arslanlar S, Yepuri J, Montrose M, Ahn CW, Shah JP Digestive diseases and sciences 2014 Jan
- An Automated Model Using Electronic Medical Record Data Identifies Patients with Cirrhosis at High Risk for Readmission.
  Singal AG, Rahimi RS, Clark C, Ma Y, Cuthbert JA, Rockey DC, Amarasingham R Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2013 Apr
- Long-term benefit of hepatitis C therapy in a safety net hospital system: a cross-sectional study with median 5-year follow-up.
  Singal AG, Dharia TD, Malet PF, Alqahtani S, Zhang S, Cuthbert JA BMJ open 2013 3 9 e003231
- Multiple factors contribute to positive results for hepatitis A virus immunoglobulin M antibody.
  Alatoom A, Ansari MQ, Cuthbert J Archives of pathology & laboratory medicine 2013 Jan 137 1 90-5
- Continuous Furosemide Infusion in the Management of Ascites.
  Rogers NA, Gupta S, Cuthbert JA Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2012 Feb
- Predictors of liver transplant eligibility for patients with hepatocellular carcinoma in a safety net hospital.
  Singal AG, Chan V, Getachew Y, Guerrero R, Reisch JS, Cuthbert JA Digestive diseases and sciences 2012 Feb 57 2 580-6
- Acute kidney injury and chronic kidney disease in hospitalized patients with cirrhosis.
  Warner NS, Cuthbert JA, Bhore R, Rockey DC Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2011 Dec 59 8 1244-51
- Hepatitis A: old and new.
  Cuthbert JA Clinical microbiology reviews 2001 Jan 14 1 38-58
- Multiple mechanisms, independent of sterol regulatory element binding proteins, regulate low density lipoprotein gene transcription.
  Makar RS, Lipsky PE, Cuthbert JA Journal of lipid research 2000 May 41 5 762-74
- Overexpression of cholesterol 7alpha-hydroxylase (CYP7A) in mice lacking the low density lipoprotein (LDL) receptor gene. LDL transport and plasma LDL concentrations are reduced.
  Spady DK, Cuthbert JA, Willard MN, Meidell RS The Journal of biological chemistry 1998 Jan 273 1 126-32
- Regulation of proliferation and Ras localization in transformed cells by products of mevalonate metabolism.
  Cuthbert JA, Lipsky PE Cancer research 1997 Aug 57 16 3498-505
- Hepatitis C: progress and problems.
  Cuthbert JA Clinical microbiology reviews 1994 Oct 7 4 505-32
- Inhibition by 6-fluoromevalonate demonstrates that mevalonate or one of the mevalonate phosphates is necessary for lymphocyte proliferation.
  Cuthbert JA, Lipsky PE The Journal of biological chemistry 1990 Oct 265 30 18568-75
- Detection of familial hypercholesterolemia by assaying functional low-density-lipoprotein receptors on lymphocytes.
  Cuthbert JA, East CA, Bilheimer DW, Lipsky PE The New England journal of medicine 1986 Apr 314 14 879-83

Research

Ascites and complications of liver disease
Jaundice and acute hepatitis
Medical education