Lenette Lu, M.D., Ph.D.

Lenette Lu, M.D., Ph.D.

  • Internal Medicine - Infectious Diseases and Geographic Medicine


Lenette Lu, M.D., Ph.D., is an Assistant Professor in the Department of Internal Medicine and the Department of Immunology at UT Southwestern Medical Center. She is an infectious disease physician-scientist.

Dr. Lu earned her medical degree and her doctoral degree in molecular virology at Case Western Reserve University School of Medicine. She completed a residency in internal medicine at New York-Presbyterian/Weill Cornell Medical Center and a clinical fellowship in infectious diseases at Massachusetts General Hospital and Brigham and Women’s Hospital. She completed a postdoctoral research fellowship at the Harvard School of Public Health and the Ragon Institute of MGH, MIT, and Harvard.

Certified by the American Board of Internal Medicine in infectious diseases and internal medicine, she joined the UT Southwestern faculty in 2019.

Dr. Lu's research focuses on how antibodies interface with the host-microbe in infectious diseases. Her studies focus on Mycobacterium tuberculosis (Mtb), the bacterium that infects one out of four people worldwide and causes tuberculosis. Her goal is to increase understanding of the immune response to infection and, ultimately, to translate observations from humans to models of disease to further inform and direct human studies that could direct diagnostic, therapeutic, and vaccine development.

Dr. Lu is a member of the American Association of Immunologists and the Infectious Diseases Society of America. In 2021, she received the American Society for Clinical Investigation’s Young Physician Scientist Award.

Education & Training
  • Medical School - Case Western Reserve University (2006-2010)
  • Graduate School - Case Western Reserve University (2002-2009), Molecular Virology
  • Fellowship - Massachusetts General Hospital (2013-2015), Infectious Diseases
  • Residency - New York Presbyterian Hospital, Cornell Campus (2010-2013), Internal Medicine
  • Other Post Graduate Training - Case Western Reserve University (2002-2009)
Professional Associations & Affiliations
  • American Association of Immunologists
  • Infectious Diseases Society of America
Honors & Awards
  • Young Physician Scientist Award 2021, American Society for Clinical Investigation
  • Disease-Oriented Clinical Scholar (DOCS) Award 2019, UT Southwestern
  • Maxwell Finland Award for Excellence in Research 2017, Massachusetts Infectious Diseases Society
  • K08 Clinical Scientist Research Career Development Award 2017, National Institutes of Health
Books & Publications
  • Host microbial interactions in infectious diseases
  • Antibody functions in tuberculosis
  • Antibody effector functions
  • Antibody glycosylation
  • Humoral immunity
  • Tuberculosis