- Medical School - University of California, San Francisco (1996-2000)
- Residency - Duke University Medical Center (2000-2003), Pediatrics
- Fellowship - Children's Hospital of Philadelphia (2003-2006), Pediatric Endocrinology
- Other Post Graduate Training - University of Massachusetts Medical School (2008-2010)
- Graduate School - University of Massachusetts Medical School (2008-2010), Clinical Investigation
Olga Gupta, M.D.
- Dedman Family Scholar in Clinical Care
- Pediatrics - Endocrinology
Dr. Olga Gupta, M.D., received her undergraduate degree in Biomedical Engineering from Duke University, and her medical degree from the University of California San Francisco, followed by residency training in Pediatrics at Duke University, and a fellowship in Pediatric Endocrinology at the Children’s Hospital of Philadelphia. She joined the faculty of the University of Massachusetts Medical School in 2007 then moved to the University of Texas Southwestern in 2012. She was appointed the Medical Director of the pediatric Center for Obesity And Consequences of Health clinic in 2016. Under her leadership the COACH program is building an interdisciplinary team of pediatric subspecialists (endocrinology, cardiology, gastroenterology), nutritionists, physical therapists, social workers, behavioral psychologists and bariatric surgeons to create a comprehensive and productive environment to care for this vulnerable patient population.
The central goals of Dr. Gupta’s research are to better understand the psychosocial mechanisms leading to poor adherence to diabetes self-management tasks in young individuals with type 1 diabetes mellitus, and to develop novel behavioral interventions that are safe and effective for this population. Her recent publications on this topic revealed a clinically and statistically significant change in HbA1c at 3 months for the adolescent participants who received the intervention (a pet fish with instructions for pairing fish care with diabetes self-management tasks) compared with their peers in the control group (usual care). (Maranda et al., The Diabetes Educator, 2015). This work was featured on an NIH podcast and in the New York Times Well Section. She also demonstrated that youth who actively care for at least one household pet were 2.5 times more likely to have good glycemic control compared to children who didn’t care for a pet (Maranda and Gupta, PLoS ONE, 2016). Dr. Gupta has a firm commitment to serving pediatric patients with diabetes and through her research she strives to have a positive impact on the health of this population.
- Pediatric Endocrinology Society (2003)
- American Diabetes Association (2003)
- American Association of Clinical Endocrinologists (2003-2006)
- Behavioral Research in Diabetes Group Exchange (2013)
- American Academy of Pediatrics (2000-2003)
- The Endocrine Society (2003)
- Dedman Family Scholar in Clinical Care 2012
- First Place Poster 2005, National Cooperative Growth Study, Genentech
- Outstanding Patient-Oriented Research Poster 2006, Institute for Diabetes, Obesity and Metabolism Spring Symposium and Kroc Lecture
- Best Paper Published from 2008's "Novel Insights from Clinical Practice" 2009, Hormone Research
- Translational Medicine and Science Retreat 2010-2011, Poster Award
- Leadership Emerging in Academic Departments 2015, UT Southwestern Medical Center
- Research Fellowship Grant 2005-2006, Lawson Wilkins Pediatric Endocrine Society
Premature Thelarche in The 5-Minute Pediatric Consult, 4th Edition, M. Schwartz, L. Bell Jr, P. Bingham, E. Chung, D. Friedman, A. Mulberg, R. Tanel, eds.
Hardy O, Kelly A. (2005), Philadelphia, PA, Lippincott Williams & Wilkins.
Hypoglycemia in Maternal, Fetal and Neonatal Physiology, S. Blackburn, ed.
Hardy O, Stanley C. (2012), Missouri, Elsevier
Hyperinsulinism of Infancy: Localization of Focal Forms in Pediatric PET Imaging, M. Charron, ed.
Hardy O, Stanley C. (2006), New York, Springer
- Premature Thelarche in The 5-Minute Pediatric Consult, 4th Edition, M. Schwartz, L. Bell Jr, P. Bingham, E. Chung, D. Friedman, A. Mulberg, R. Tanel, eds.
Multifetal Pregnancy May Increase the Risk for Severe Maternal and Neonatal Vitamin D Deficiency
Nwosu, Benjamin U. MD; Soyka, Leslie A. MD; Angelescu, Amanda MD; Hardy, Olga T. MD; Lee, Mary M. MD The Endocrinologist 2008 18 4 172-175
Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals.
Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, Cao L, Lynes MD, Tseng YH, Elmquist JK, Williams KW, Lin HV, Scherer PE Cell metabolism 2016 Sep 24 3 420-33
Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance.
DiStefano MT, Roth Flach RJ, Senol-Cosar O, Danai LV, Virbasius JV, Nicoloro SM, Straubhaar J, Dagdeviren S, Wabitsch M, Gupta OT, Kim JK, Czech MP Molecular metabolism 2016 Dec 5 12 1149-1161
Association between Responsible Pet Ownership and Glycemic Control in Youths with Type 1 Diabetes.
Maranda L, Gupta OT PloS one 2016 11 4 e0152332
Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion.
Senol-Cosar O, Flach RJ, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, Hardy OT, Noh HL, Kim JK, Wabitsch M, Scherer PE, Czech MP Nature communications 2016 7 10686
Activated Kupffer cells inhibit insulin sensitivity in obese mice.
Tencerova M, Aouadi M, Vangala P, Nicoloro SM, Yawe JC, Cohen JL, Shen Y, Garcia-Menendez L, Pedersen DJ, Gallagher-Dorval K, Perugini RA, Gupta OT, Czech MP FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 Mar
A Novel Behavioral Intervention in Adolescents With Type 1 Diabetes Mellitus Improves Glycemic Control: Preliminary Results From a Pilot Randomized Control Trial.
Maranda L, Lau M, Stewart SM, Gupta OT The Diabetes educator 2015 Jan
Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction.
Sun K, Park J, Gupta OT, Holland WL, Auerbach P, Zhang N, Goncalves Marangoni R, Nicoloro SM, Czech MP, Varga J, Ploug T, An Z, Scherer PE Nature communications 2014 5 3485
Parental Mastery of Continuous Subcutaneous Insulin Infusion Skills and Glycemic Control in Youth with Type 1 Diabetes.
Mitchell K, Johnson K, Cullen K, Lee MM, Hardy OT Diabetes technology & therapeutics 2013 Jun
Increased Toll-like receptor (TLR) mRNA expression in monocytes is a feature of metabolic syndrome in adolescents.
Hardy OT, Kim A, Ciccarelli C, Hayman LL, Wiecha J Pediatric obesity 2013 Feb 8 1 e19-23
Body mass index, treatment practices, and mortality in patients with acute heart failure.
Fitzgibbons TP, Hardy OT, Lessard D, Gore JM, Yarzebski J, Goldberg RJ Coronary artery disease 2009 Dec 20 8 536-43
Long-term non-surgical therapy of severe persistent congenital hyperinsulinism with glucagon.
Mohnike K, Blankenstein O, Pfuetzner A, Pötzsch S, Schober E, Steiner S, Hardy OT, Grimberg A, van Waarde WM Hormone research 2008 70 1 59-64
Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents.
Hardy OT, Hohmeier HE, Becker TC, Manduchi E, Doliba NM, Gupta RK, White P, Stoeckert CJ, Matschinsky FM, Newgard CB, Kaestner KH Molecular endocrinology (Baltimore, Md.) 2007 Mar 21 3 765-73
Accuracy of [18F]fluorodopa positron emission tomography for diagnosing and localizing focal congenital hyperinsulinism.
Hardy OT, Hernandez-Pampaloni M, Saffer JR, Scheuermann JS, Ernst LM, Freifelder R, Zhuang H, MacMullen C, Becker S, Adzick NS, Divgi C, Alavi A, Stanley CA The Journal of clinical endocrinology and metabolism 2007 Dec 92 12 4706-11
Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha.
Gupta RK, Gao N, Gorski RK, White P, Hardy OT, Rafiq K, Brestelli JE, Chen G, Stoeckert CJ, Kaestner KH Genes & development 2007 Apr 21 7 756-69
Improving medication adherence in the pediatric population using integrated care of companion animals.
Gupta OT, Wiebe DJ, Pyatak EA, Beck AM Patient education and counseling 2018 May
Syndrome X (Metabolic Syndrome) for Generation Z! Why?
Gupta OT Metabolic syndrome and related disorders 2015 Feb
PTU-associated vasculitis in a girl with Turner Syndrome and Graves' disease.
Hardy OT, Smolinski KN, Yan AC, Grimberg A Pediatric emergency care 2006 Jan 22 1 52-4
Uric Acid, Parathyroid Hormone, and Vitamin D: New Players in an Old Game.
Cartaya J, Gupta OT Metabolic syndrome and related disorders 2016 Apr 14 3 135-6
Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesity.
Hardy OT, Perugini RA, Nicoloro SM, Gallagher-Dorval K, Puri V, Straubhaar J, Czech MP Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2011 Jan-Feb 7 1 60-7
Diagnosis and localization of focal congenital hyperinsulinism by 18F-fluorodopa PET scan.
Hardy OT, Hernandez-Pampaloni M, Saffer JR, Suchi M, Ruchelli E, Zhuang H, Ganguly A, Freifelder R, Adzick NS, Alavi A, Stanley CA The Journal of pediatrics 2007 Feb 150 2 140-5
Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia.
Saddic LA, Nicoloro SM, Gupta OT, Czech MP, Gorham J, Shernan SK, Seidman CE, Seidman JG, Aranki SF, Body SC, Fitzgibbons TP, Muehlschlegel JD Cardiovascular diabetology 2017 Jul 16 1 87
Camp-based multi-component intervention for families of young children with type 1 diabetes: A pilot and feasibility study.
Gupta OT, MacKenzie M, Burris A, Jenkins BB, Collins N, Shade M, Santa-Sosa E, Stewart SM, White PC Pediatric diabetes 2017 Dec
Visceral Adipose Tissue Mesothelial Cells: Living on the Edge or Just Taking Up Space?
Gupta OT, Gupta RK Trends in endocrinology and metabolism: TEM 2015 Oct 26 10 515-23
Engaging Teens and Parents in Collaborative Practice: Perspectives on Diabetes Self-Management.
Sullivan-Bolyai S, Bova C, Johnson K, Cullen K, Jaffarian C, Quinn D, Aroke EN, Crawford S, Lee MM, Gupta O The Diabetes educator 2014 Jan
Effects of a multicomponent wellness intervention on dyslipidemia among overweight adolescents.
Hardy OT, Wiecha J, Kim A, Salas C, Briceno R, Moody K, Becker J, Glazer G, Ciccarelli C, Shi L, Hayman LL Journal of pediatric endocrinology & metabolism : JPEM 2012 25 1-2 79-82
Do Atypical Antipsychotic Agents Trigger Autoimmune Diabetes?
Nwosu, Benjamin U. MD; Hardy, Olga T. MD; Angelescu, Amanda MD; Soyka, Leslie A. MD; Lee, Mary M. MD The Endocrinologist 2009 19 2 85-87
What causes the insulin resistance underlying obesity?
Hardy OT, Czech MP, Corvera S Current opinion in endocrinology, diabetes, and obesity 2012 Apr 19 2 81-7
- Multifetal Pregnancy May Increase the Risk for Severe Maternal and Neonatal Vitamin D Deficiency
- Diabetes in adolescents
- Congenital hyperinsulinism