A cardiology powerhouse – and now a community resource
October 6, 2016
Pradeep Mammen, M.D., is a Professor in the Department of Internal Medicine’s Division of Cardiology at UT Southwestern Medical Center.
Dr. Mammen’s clinical and investigative focus is heart failure/heart transplantation, and he serves as Medical Director of the Neuromuscular Cardiomyopathy Clinic, as well as Director of Translational Research for the Advanced Heart Failure and Transplant Cardiology Program.
He is also a member of the UT Southwestern Hamon Center for Regenerative Science & Medicine and runs a molecular laboratory that is funded through grants from the National Institutes of Health and the American Heart Association. Dr. Mammen’s scientific interests revolve around the molecular mechanisms underlying heart failure and he oversees a laboratory dedicated to better understanding this disease entity. The goal is to eventually develop new, targeted heart failure therapies.
After earning his medical degree at the University of Wisconsin School of Medicine, he completed an internal medicine internship and residency at the University of Iowa Hospitals and Clinics, followed by fellowships in cardiology, heart failure/cardiac transplantation, and molecular cardiology at UT Southwestern.
A Fellow of both the American Heart Association and the American College of Cardiology, Dr. Mammen is board certified in internal medicine and cardiovascular medicine. He is one of only 500 U.S. cardiologists board certified in advanced heart failure/transplant cardiology.
Dr. Mammen has published more than 40 journal articles and delivered a number of invited lectures. He has served as a reviewer for publications that include the American Heart Journal, American Journal of Cardiology, American Journal of Physiology–Heart and Circulatory Physiology, Circulation: Heart Failure, Journal of the American College of Cardiology, and the Journal of Cardiac Failure. In addition, Dr. Mammen serves on the Scientific Review Committee for various study sections for the National Institutes of Health and the American Heart Association.
He is a member of professional organizations that include the American College of Cardiology (Heart Failure/VAD/Heart Transplantation Section), American Heart Association (Council on Basic Cardiovascular Sciences as well as the Council on Clinical Cardiology), Heart Failure Society of America, International Society of Heart and Lung Transplantation, and American College of Physicians.
Dr. Mammen also serves as a member of UT Southwestern’s Class of 2013 LEAD Program. He was among 30 faculty members identified as having leadership potential and chosen by the Dean’s Office to take part in a leadership-training program for junior faculty members.
Dr. Mammen and his wife have a son and a daughter.
Pradeep Mammen, M.D., finds great satisfaction in his dual role as a clinician-scientist at UT Southwestern Medical Center: As a clinician, he contributes directly to his patients’ health in the clinic, and as a scientist, he pioneers new treatments in the research lab.
Dr. Mammen is an expert in advanced heart failure, ventricular assist devices (VADs), and heart transplantation. He has a special interest in neuromuscular cardiomyopathy – heart failure caused by neuromuscular disorders – and he serves as the Medical Director of UT Southwestern’s dedicated Neuromuscular Cardiomyopathy Clinic, which he founded in 2010. It remains one of only a handful of dedicated neuromuscular cardiomyopathy clinics in the United States.
Meanwhile, Dr. Mammen is one of only 500 cardiologists in the nation who is board certified in advanced heart failure/transplant cardiology. He also performs cardiopulmonary stress testing – a specialized test for advanced heart failure – as well as procedures such as heart biopsies and cardiac catheterizations.
On the research side, Dr. Mammen is the Director of Translational Research for the Advanced Heart Failure Program and investigates the molecular mechanisms underlying heart failure. The goal of his molecular cardiology laboratory is to develop novel therapeutic approaches for the treatment of patients with heart failure. Dr. Mammen’s laboratory is funded through grants from the National Institute of Health and the American Heart Association.
He is optimistic about the future of heart-failure treatment.
“Heart failure, ventricular assist devices, and cardiac transplantation are some of the fastest-growing subspecialties within cardiology,” he says. “And fields like regenerative biology and stem-cell transplantation are enabling us to look at ways to regenerate heart tissue – which helps damaged hearts repair themselves.”
Dr. Mammen is also proud to belong to UT Southwestern’s group of experienced and skilled specialists, a team that includes physicians and surgeons as well as clinicians such as nurse coordinators and practitioners.
“Everything the heart failure/transplant team does, we do as a team – not as individuals – and our patients really benefit from that,” Dr. Mammen says. “UT Southwestern wouldn’t have the excellent heart transplantation survival rates it does if it weren’t for this well-oiled machine, and I’m proud that as a group, we’re able to give these very sick patients another chance at life.”