Saad Khan, M.D., is a medical oncologist and Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He joined UT Southwestern in 2012.

Dr. Khan specializes in the treatment and research of cancers of the head and neck, as well as the unique challenges for patients with this disease. 

His mission at UT Southwestern is to identify cancer biomarkers that predict which treatments are best for individual patients.

Dr. Khan received his medical degree from Punjab Medical College in Pakistan and then completed his internship at the Mayo Clinic in Minnesota. Throughout his residency at the University of Massachusetts and fellowship at Fox Chase Cancer Center at Temple University in Philadelphia he focused on caring for those affected by cancer.

During his training, he explored the molecular signatures of the most aggressive cancers to better understand why some patients don’t respond to standard chemotherapy.

He is board certified in internal medicine and medical oncology.

Dr. Khan was named a Texas Monthly Super Doctor in 2018.

Personal Note

When he’s not chasing after his two toddlers, Dr. Khan enjoys squash and rock climbing.

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Meet Dr. Khan

A diagnosis of cancer is stressful for a patient. Saad Khan, M.D., a medical oncologist at UT Southwestern Medical Center who focuses on head and neck cancers and lung cancer, believes communication is the key to overcoming anxiety.

"One thing I always like to do with patients is just talk. I think having the opportunity to speak in an unhurried environment with someone who's listening is very useful," Dr. Khan says.

Dr. Khan takes the time to develop relationships with his patients so they can ask any difficult questions that might be on their mind – questions like, “How long will I live?” or “What should I expect during the course of my treatment?”

"My ultimate goal is to come up with better treatments for patients.”

Even after their chemotherapy, Dr. Khan wants his patients to stay in touch so he can make sure they don't develop any problems later with speech and swallowing – common long-term side effects from head and neck cancer treatment.

In addition to his work with patients, Dr. Khan spends significant time researching new approaches to treating cancer. His research includes creating drugs that offer targeted therapy based on each patient's specific cancer, in the hope that personalized care will help patients get better more quickly and with fewer side effects.

He also is spearheading clinical trials at UT Southwestern and is developing new treatments to advance care for head and neck cancer.

Uniting patient care and science offers him better insight into how cancer behaves.

"With a better understanding of cancer, we can translate that into clinical trials and better treatments," he says.

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Education & Training
  • Fellowship - Temple University School of Medicine (2009-2012), Hematology Oncology
  • Residency - University of Massachusetts School of Medicine (2006-2009), Internal Medicine
  • Residency - Mayo School of Graduate Medical Education (2005-2006), General Surgery
  • Medical School - Punjab Medical College (1998-2003)
Professional Associations & Affiliations
  • American Association for Cancer Research (2010), Member
  • American Society of Clinical Oncology (2011), Member
  • Head, Neck, and Pancreatic Cancer

Clinical Focus

  • Medical Treatment of Lung Cancer
  • Head & Neck Cancers
  • Medical Treatment of Head and Neck Cancer

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Q&A by Dr. Khan

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