- Residency - M.D. Anderson Cancer Center (2014-2018), Radiation Oncology
- Internship - Santa Clara Valley Medical Center (2013-2014), Transitional Year
- Medical School - Stanford University School of Medicine (2009-2013)
Wen Jiang, M.D., Ph.D.
- Radiation Oncology
- Radiation Therapy for Brain Tumors
- Brain & Spinal Cord Cancer
Wen Jiang, M.D., Ph.D., is an Assistant Professor of Radiation Oncology at UT Southwestern Medical Center, specializing in radiation therapy for central nervous system cancer.
He attended graduate school at the University of Toronto where he earned his degree in bioengineering. Dr. Jiang earned his M.D. from Stanford University School of Medicine and, shortly after, completed a radiation oncology residency at UT MD Anderson Cancer Center.
In his free time, Dr. Jiang enjoys watching movies, traveling, and spending time with his family.
Meet Dr. Jiang
Wen Jiang, M.D., Ph.D., focuses on treating cancer sites of the central nervous system with radiation. His dream of becoming an oncologist was driven by his desire to find a cure for cancer. His interest in the field of radiation oncology, however, originated during his postdoctoral fellowship at Mass General Hospital.
“Given my training as an engineer, I was just fascinated by the technological tools available at the doctors' disposal and felt that there were unlimited opportunities to develop exciting new technologies to treat cancer,” he says.
As an Assistant Professor in UT Southwestern’s Department of Radiation Oncology, Dr. Jiang’s main focus will be on the treatment of CNS benign and malignant tumors.
Dr. Jiang’s clinical research is focused on the understanding of the body’s immune system and how it interacts with cancer cells, and how these cells develop the abilities to evade immune detection.
- American Society for Radiation Oncology (ASTRO) (2014)
- American Association for Cancer Research (AACR) (2014)
- American Society of Clinical Oncology (ASCO) (2016)
- Society for Neuro-Oncology (SNO) (2016)
- ASCO Young Investigator Award 2017
- RSNA Roentgen Award 2017
- RSNA Resident Research Grant 2016
- Carleton University Young Alumni Achievement Award 2014
The reciprocity between radiotherapy and cancer immunotherapy.
Wang Y, Liu Z, Yuan H, Deng W, Li J, Huang Y, Kim BYS, Story MD, Jiang W Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Nov
NCR- group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development.
Liu Y, Song Y, Lin D, Lei L, Mei Y, Jin Z, Gong H, Zhu Y, Hu B, Zhang Y, Zhao L, Teo HY, Qiu J, Jiang W, Dong C, Wu D, Huang Y, Liu H, EBioMedicine 2019 Mar 41 333-344
Therapeutic remodeling of the tumor microenvironment enhances nanoparticle delivery
Chen Y, Liu X, Yuan H, von Roemeling CA, Qie Y, Knight JA, Wang Y, Yun K, Jiang W,* Kim BYS Advanced Science 2019 6
A clonal precursor of bone, cartilage, and hematopoietic niche stromal cells
Chan C, Lindau P, Jiang W (co-first author), Chen J, Zhang L, Chen C-C, Seita J, Sahoo D, Kim J, Lee A, Park S, Nag D, Gong Y, Kulkarni S, Luppen C, Theologis A, Wan D, DeBoer A, Seo E, Vincent-Tompkins J, Loh K, Walmsley G, Kraft D, Wu J, Longaker M, Weissman IL 2013 110 12643-12648
Lessons from immuno-oncology: a new era for cancer nanomedicine?
Jiang W, Yuan H, Chan CK, von Roemeling C, Yan Z, Weissman IL, Kim BYS Nature Rev Drug Discovery 2017 16 169-170
Increased vessel perfusion predicts the therapeutic efficacy of immune checkpoint blockade
Zheng X, Fang Z, Wang X, Zhang C, Yin R, Wen C, Liu X, Deng S, Zhou P, Hu H, Chen X, Wang X, Zhao Y, Xin L, Lin SH, Kim BYS, Jiang W, Wu Q, Huang YH Journal of Clinical Investigation 2018 128 2104-2115
Mutant LKB1 confers enhanced radiosensitization in combination with trametinib in KRAS-mutant non-small cell lung cancer
Wang Y, Li N, Jiang W, Deng W, Ye R, Xu C, Qiao Y, Sharma A, Zhang M, Hung MC, Lin SH Clinical Cancer Research 2018 24 22 5744-5756
Immune modulating nanomedicine for cancer therapy
Liu Z, Jiang W (co-first author), Nam J, Moon JJ, Kim BYS Nano Letters 2018 18 6655-6659
Advances and challenges of nanotechnology based drug delivery systems
Jiang W, Kim BYS, Rutka JT, Chan WCW Expert Opinion in Drug Delivery 2008 4 621-633
Immunogenic priming of tumor microenvironment with radiotherapy
Jiang W, Chan CK, Weissman IL, Kim BYS, Hahn SM Trends in Cancer (Cell Press) 2016 2 638-645
Compact biocompatible and derivatizable quantum dots via RAFT-mediated synthesis of coordinating imidazole-based random copolymer ligand
Liu W, Greytak AB, Lee J, Park J, Wong CR, Marshall L, Jiang W, Curtin P, Ting AY, Nocera DG, Jain RK, Bawendi MG Journal American Chemical Society 2010 132 472-483
Multivalent bi-specific nano-bioconjugate engager for targeted cancer immunotherapy
Yuan H, Jiang W (co-first author), von Roemeling CA, Qie Y, Liu X, Chen Y, Wharen RE, Yun K, Bu G, Knutson KL, Kim BYS Nature Nanotechnology 2017 12 763-769
Assessing near-infrared quantum dots for deep tissue, organ, animal imaging
Jiang W, Singhal A, Kim BYS, Zheng J, Rutka JT, Wang C, Chan WCW Journal of the Association for Laboratory Automation 2007 13 6-12
Multistage nanoparticle delivery system demonstrates deep penetration into tumor tissue through MMP-activated size change
Wong CR, Stylianopoulos T, Cui J, Martin J, Chauhan VP, Jiang W, Popovic Z, Jain RK, Fukumura D, Bawendi MG 2011 108 2426
RAD50 expression is associated with poor clinical outcomes after radiotherapy in resected non-small cell lung cancer
Wang Y, Gudikote J, Yan J, Deng W, Jiang W, Li N, Ye R, Hobbs BP, Wang J, Swisher SG, Fujimoto J, Wistuba II, Komaki R, Heymach JV, Lin SH 2017 24 341-350
Efficacy and toxic effects of cancer immunotherapy combinations: a double-edged sword
Tang C, Jiang W, Yap TA JAMA Oncology 2018 4 8 1116-1117
Semiconductor quantum dots as contrast agents for whole animal imaging
Jiang W, Papa E, Fischer H, Mardyani S, Chan WCW Trends in Biotechnol (Cell Press) 2004 22 607-609
Biodegradable quantum dot nanocomposites enable live cell labelling and imaging of cytoplasmic targets
Kim BYS, Jiang W (co-first author), Oreopolous J, Yip CM, Rutka JT, Chan WCW Nano Letters 2008 8 3887-3892
Optimizing the synthesis of red to near-IR-emitting CdS-capped CdTexSe1-x alloyed quantum dots for biomedical imaging
Jiang W, Singhal A, Zheng J, Wang C, Chan WCW Chemistry of Materials 2006 18 4845-4854
S100A4 is a biomarker and regulator of glioma stem cells that is critical for mesenchymal transition in glioblastoma
Chow KH, Park HJ, George J, Yamamoto K, Gallup AD, Graber J, Chen YX, Jiang W, Steindler D, Neilson EG, Kim BYS, Yun K Cancer Research 2017 77 19 5360-5373
Remodel tumor vasculature to enhance the delivery of intermediate-sized nanoparticles into solid tumors
Jiang W, An Y, Huang Y, Kim BYS ACS Nano 2015 9 8689-96
A tale of two disciplines
Jiang W Nature Nanotechnology 2016 11 732
Surface-plasmon-coupled emission of quantum dots
Gryczynki I, Malicka J, Jiang W, Fischer H, Chan WCW, Gryczynki Z, Grudzinski W, Lakowicz JR Journal of Physical Chemistry B 2005 109 1088-1093
Improving immune-vascular crosstalk for cancer immunotherapy
Huang YH, Kim BYS, Chan CK, Hahn SM, Weissman IL, Jiang W Nature Rev Immunology 2018 18 195-203
Surface modification of nanoparticle enables selective evasion of phagocytosis by distinct macrophage phenotypes
Qie Y, Yuan H, Chen Y, Von Roemeling C, Liu X, Kim Y, Knight JA, Jiang W, Kim BYS Scientific Reports 2016 6 26269
Design and characterization of lysine cross-linked mercapto-acid biocompatible quantum dots
Jiang W, Mardyani S, Fischer H, Chan WCW Chemistry of Materials 2006 18 872-878
Nanoparticle-mediated cellular response is size-dependent
Jiang W, Kim BYS, Rutka JT, Chan WCW Nature Nanotechnology 2008 3 145-150
Breaking bown the barriers to precision cancer nanomedicine
von Roemling C, Jiang W (co-first author),* Chan CK, Weissman IL, Kim BYS Trends in Biotechnol (Cell Press) 2017 35 159-171
Designing next generation cancer nanomedicine for immuno-oncology
Jiang W, von Roemeling C, Qie Y, Chen Y, Liu X, Chen J, Kim BYS 2017 1 2 0029
The reciprocity cancer immunotherapy and radiotherapy
Wang Y, Liu ZG, Huang YH, Li J, Kim BYS, Story MD, Jiang W Clinical Cancer Research 2018
- The reciprocity between radiotherapy and cancer immunotherapy.
- Tumor microenvironment
- Cancer immunotherapy
- Tumor immunology
- Cancer nanomedicine
- Innate immune checkpoint
- Radiation Therapy for Brain Tumors
- Brain & Spinal Cord Cancer
- Brain Metastases