The transfer of molecular biology technology from basic research provides the pathologist with a host of new tools to aid in the diagnosis of disease. The Laboratory for Molecular Diagnostics is a state-of-the-art laboratory capable of utilizing cutting-edge molecular techniques to help answer difficult diagnostic problems.
Quality is assured throughout the testing process beginning with robust assay design and technical and clinical validation. Commercial proficiency testing and sample exchange provide assurance of assay integrity. The academic setting provides further enhancement of the assays’ clinical utility as researched by pathology residents and molecular pathology fellows participating in clinical investigations.
Every sample is analyzed by dedicated technologists who are experts in the performance of molecular techniques. Assays for hematologic, infectious, and inherited disorders are performed. The assay formats include liquid-phase hybridization, DNA sequencing, qualitative and quantitative PCR, and real-time quantitative PCR.
The current test menu includes assays for T- & B-cell gene rearrangement, bcr-abl, bcl-1, bcl-2, EBV, CMV, VZV, parvovirus B19, hepatitis C, HHV-8, HHV-6, Factor V Leiden, prothrombin, MTHFR, bone marrow engraftment analysis, and EGFR mutation analysis in NSCLC.
Prasad Koduru, Ph.D., FACMG, Director, Genetic Testing: 214-648-0977 and 214-648-0975
Dwight Oliver, M.D., Section Medical Director: 214-648-0960
Kathleen Wilson, M.D.: 214-648-0978