- Residency - UT Southwestern Medical Center (2006-2010), Pathology
- Medical School - Stavropol State Medical Academy, Russian Federation (1982-1989)
Elena Lucas, M.D.
- Pathology
- Cytopathology
- Gynecologic Pathology
Biography
Elena Lucas, M.D., is an Associate Professor in the Department Pathology at UT Southwestern Medical Center. She specializes in cytopathology and gynecologic pathology.
Dr. Lucas earned her medical degree at the Stavropol State Medical Institute and completed a residency in laboratory medicine at Central Regional Children's Hospital in Stavropol, Russia. She performed her residency in anatomic and clinical pathology at UT Southwestern, where she was Chief Resident in her final year and where she then gained advanced training through a fellowship in cytopathology.
Certified by the American Board of Pathology in anatomic and clinical pathology and cytopathology, she joined the UT Southwestern faculty in 2011.
Among her other roles, Dr. Lucas is Medical Director of Surgical Pathology and Immunohistochemistry at Parkland Health. She is Rotation Director of the surgical pathology bootcamp and hot-seat rotations within the UT Southwestern Pathology Residency Program.
Her research interests include immuno-oncology biomarkers; cervical, endometrial, and ovarian carcinoma; and endometrial precancers. She contributed to the book Diagnosing Non-Small Cell Carcinoma in Small Biopsy and Cytology and has published numerous academic articles related to her areas of expertise.
She is a member of the College of American Pathologists, the American Society for Clinical Pathology, the American Society of Cytopathology, the United States and Canadian Academy of Pathology, and the International Society of Gynecological Pathologists.
Personal Note
Outside of work, Dr. Lucas enjoys reading and travel.
Education & Training
Professional Associations & Affiliations
- American Society for Clinical Pathology
- American Society of Cytopathology
- College of American Pathologists
- International Society of Gynecological Pathologists
- United States and Canadian Academy of Pathology
Honors & Awards
- Anatomic Pathology Resident Teaching Award, 2013, 2014, 2022, UT Southwestern
- Chief Resident 2009-2010, UT Southwestern Anatomic and Clinical Pathology Residency
- First Qualification Category 1997, Public Healthcare Department, Stavropol, Russia
- Diploma with Highest Academic Distinction (Summa Cum Laude equivalent) 1989, Stavropol State Medical Institute
Books & Publications
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Books
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Mimickers of Lung Carcinoma is Cytology and Small Biopsy Specimens in Diagnosing Non-Small Cell Carcinoma in Small Biopsy and Cytology
Lucas E, Sahoo S (2015), New York, Springer Science
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Mimickers of Lung Carcinoma is Cytology and Small Biopsy Specimens in Diagnosing Non-Small Cell Carcinoma in Small Biopsy and Cytology
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Publications
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β-catenin, Pax2, and Pten Panel Identifies Precancers Among Histologically Subdiagnostic Endometrial Lesions.
Aguilar M, Chen H, Sahoo SS, Zheng W, Grubman J, SoRelle JA, Lucas E, Castrillon DH, The American journal of surgical pathology 2023 May 47 5 618-629 -
Aggressive High-grade Uterine Sarcoma Harboring MEIS1-NCOA2 Fusion and Amplification of Multiple 12q13-15 Genes: A Case Report With Morphologic, Immunohistochemical, and Molecular Analysis.
Niu S, Rivera-Colon G, Lucas E, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2023 Jan -
Endometrial polyps are non-neoplastic but harbor epithelial mutations in endometrial cancer drivers at low allelic frequencies.
Sahoo SS, Aguilar M, Xu Y, Lucas E, Miller V, Chen H, Zheng W, Cuevas IC, Li HD, Hitrys D, Wachsmann MB, Bishop JA, Cantarell B, Gagan J, Koduru P, SoRelle JA, Castrillon DH, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2022 Jul -
Prevalence and prognostic significance of PD-L1, TIM-3 and B7-H3 expression in endometrial serous carcinoma.
Chen H, Molberg K, Carrick K, Niu S, Rivera Colon G, Gwin K, Lewis C, Zheng W, Castrillon DH, Lucas E, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2022 Jul -
Morules but Not Squamous Differentiation are a Reliable Indicator of CTNNB1 (?-catenin) Mutations in Endometrial Carcinoma and Precancers.
Niu S, Lucas E, Molberg K, Strickland A, Wang Y, Carrick K, Rivera-Colon G, Gwin K, SoRelle JA, Castrillon DH, Zheng W, Chen H, The American journal of surgical pathology 2022 Jul -
Low grade endometrial endometrioid adenocarcinoma: A review and update with emphasis on morphologic variants, mimics, immunohistochemical and molecular features.
Lucas E, Carrick KS, Seminars in diagnostic pathology 2022 May 39 3 159-175 -
Human Papillomavirus?Positive and ?Negative Vulvar Squamous Cell Carcinoma Are Biologically but Not Clinically Distinct.
Kolitz E, Lucas E, Hosler GA, Kim J, Hammer S, Lewis C, Xu L, Day AT, Mauskar M, Lea JS, Wang RC, The Journal of investigative dermatology 2021 Oct -
Navigating through perplex morphologic changes after exogenous hormone usage.
Chang RJ, Rivera-Colon G, Chen H, Niu S, Carrick K, Lucas E, Gwin K, Zheng W, Seminars in diagnostic pathology 2021 Oct -
Reliable Identification of Endometrial Precancers Through Combined Pax2, ?-Catenin, and Pten Immunohistochemistry.
Aguilar M, Chen H, Rivera-Colon G, Niu S, Carrick K, Gwin K, Cuevas IC, Sahoo SS, Li HD, Zhang S, Zheng W, Lucas E, Castrillon DH, The American journal of surgical pathology 2021 Sep -
PD-L1 expression in HPV-independent cervical adenocarcinoma and its prognostic significance.
Chen L, Lucas E, Zhang X, Liu Q, Zhuang Y, Lin W, Chen H, Zhou F, Histopathology 2021 Aug -
Clinical and Histopathologic Features Can Help Target Immunohistochemical Stain Use in the Diagnosis of Viral Esophagitis.
Desai N, Albahra S, Lucas E, Singal AG, Hammer STG, Gopal P, Applied immunohistochemistry & molecular morphology : AIMM 2021 Aug -
Significance of Oil-Red-O positive macrophages in bronchoalveolar lavage in diagnosing E-cigarettes or vaping product use-associated lung injury: A case series.
Niu S, Colon GR, Molberg K, Chen H, Carrick K, Yan S, Sarode V, Lucas E, Diagnostic cytopathology 2021 Jul 49 7 876-884 -
Retroperitoneal Sclerosing Angiomyolipoma with Long-Term Follow up: A Case Report with Unique Clinicopathologic and Genomic Profile.
Jia L, Panwar V, Parmley M, Lucas E, Pedrosa I, Kapur P, International journal of surgical pathology 2021 Jun 10668969211021483 -
Serial genomic analysis of endometrium supports the existence of histologically indistinct endometrial cancer precursors.
Aguilar M, Zhang H, Zhang M, Cantarell B, Sahoo SS, Li HD, Cuevas IC, Lea J, Miller DS, Chen H, Zheng W, Gagan J, Lucas E, Castrillon DH, The Journal of pathology 2021 Jan -
T Cell Receptor Repertoires Acquired via Routine Pap Testing May Help Refine Cervical Cancer and Precancer Risk Estimates.
Christley S, Ostmeyer J, Quirk L, Zhang W, Sirak B, Giuliano AR, Zhang S, Monson N, Tiro J, Lucas E, Cowell LG, Frontiers in immunology 2021 12 624230 -
PD-L1 Expression in Endocervical Adenocarcinoma: Correlation With Patterns of Tumor Invasion, CD8+ Tumor-infiltrating Lymphocytes, and Clinical Outcomes.
Rivera-Colon G, Chen H, Molberg K, Niu S, Strickland AL, Castrillon DH, Carrick K, Gwin K, Lea J, Zheng W, Lucas E, The American journal of surgical pathology 2020 Dec -
Irreversible Electroporation for Renal Ablation Does Not Cause Significant Injury to Adjacent Ureter or Bowel in a Porcine Model.
Sorokin I, Canvasser N, Johnson B, Lucas E, Cadeddu JA, Journal of endourology 2020 Dec -
Specific Biomarker Expression Patterns in the Diagnosis of Residual and Recurrent Endometrial Precancers After Progestin Treatment: A Longitudinal Study.
Chen H, Lucas E, Strickland AL, Carrick K, Gwin K, Castrillon DH, Rivera-Colon G, Niu S, Molberg KH, Zheng W, The American journal of surgical pathology 2020 Oct 44 10 1429-1439 -
Reproducibility of AJCC Criteria for Classifying Deeply Invasive Colon Cancers Is Suboptimal for Consistent Cancer Staging.
Panarelli NC, Hammer STG, Lin J, Gopal P, Nalbantoglu I, Zhao L, Cheng J, Gersten AJ, McHugh JB, Parkash V, Lucas E, Westerhoff M, The American journal of surgical pathology 2020 10 44 10 1381-1388 -
PD-L1 Expression and CD8+ Tumor-infiltrating Lymphocytes in Different Types of Tubo-Ovarian Carcinoma and Their Prognostic Value in High-grade Serous Carcinoma.
Chen H, Molberg K, Strickland AL, Castrillon DH, Carrick K, Jiang Q, Niu S, Rivera-Colon G, Gwin K, Hinson S, Lea J, Miller DS, Zheng W, Lucas E, The American journal of surgical pathology 2020 May -
Cervical Adenocarcinoma: Histopathologic Features From Biopsies to Predict Tumor Behavior.
Rivera-Colon G, Chen H, Niu S, Lucas E, Holloway S, Carrick K, Gwin K, Lea J, Zheng W, The American journal of surgical pathology 2020 Feb 44 2 247-254 -
Effects of Decalcifying Agents of Variable Duration on PD-L1 Immunohistochemistry.
Strickland AL, Blacketer S, Molberg K, Markantonis J, Lucas E, American journal of clinical pathology 2020 Jan 153 2 258-265 -
Comparison of Dako HercepTest and Ventana PATHWAY Anti-HER2 (4B5) Tests and Their Correlation With Fluorescent In Situ Hybridization in Breast Carcinoma.
Lucas E, Jabbar SB, Molberg K, Fang Y, Xie XJ, Blacketer S, Sahoo S, Applied immunohistochemistry & molecular morphology : AIMM 2019 Jul 27 6 403-409 -
Challenges in the Pap diagnosis of endocervical adenocarcinoma in situ.
Niu S, Molberg K, Thibodeaux J, Rivera-Colon G, Hinson S, Zheng W, Lucas E, Journal of the American Society of Cytopathology 2019 May - Jun 8 3 141-148 -
Age cutoff for reporting of benign-appearing endometrial cells in Papanicolaou specimens; should it be raised? A 10-year retrospective study from a large county hospital.
Hinson S, Molberg K, Mir M, Flores M, Zheng W, Lucas E, Journal of the American Society of Cytopathology 2019 Mar - Apr 8 2 78-83 -
Mismatch Repair Protein Expression in Endometrioid Intraepithelial Neoplasia/Atypical Hyperplasia: Should We Screen for Lynch Syndrome in Precancerous Lesions?
Lucas E, Chen H, Molberg K, Castrillon DH, Rivera Colon G, Li L, Hinson S, Thibodeaux J, Lea J, Miller DS, Zheng W International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2018 Oct -
PI3K Pathway Effectors pAKT and FOXO1 as Novel Markers of Endometrioid Intraepithelial Neoplasia.
Strickland AL, Rivera G, Lucas E, John G, Cuevas I, Castrillon DH International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2018 Sep -
Lung tumor in a young African American patient with sickle trait: Pieces of a puzzle.
Mir M, Parmley M, Molberg K, Hinson S, Thibodeaux J, Lucas E CytoJournal 2018 15 21 -
Effect of Varying Parameters on Irreversible Electroporation in a Porcine Model.
Canvasser NE, Lay AH, Koseoglu E, Kavoussi N, Sorokin I, Gahan JC, Lucas E, Cadeddu JA Journal of endourology 2017 Dec -
The diagnostic utility of Merkel cell polyomavirus immunohistochemistry in a fine needle aspirate of metastatic Merkel cell carcinoma of unknown primary to the pancreas.
Li L, Molberg K, Cheedella N, Thibodeaux J, Hinson S, Lucas E Diagnostic cytopathology 2017 Aug -
Metastatic Melanoma to the Bladder: Case Report and Review of the Literature.
Patil RV, Woldu SL, Lucas E, Quinn AM, Francis F, Margulis V Urology case reports 2017 Feb 11 33-36 -
Comparative Effects of Irreversible Electroporation, Radiofrequency Ablation, and Partial Nephrectomy on Renal Function Preservation in a Porcine Solitary Kidney Model.
Morgan MS, Ozayar A, Lucas E, Friedlander JI, Shakir NA, Cadeddu JA Urology 2016 May -
Expulsion of a Uterine Fibroid into the Small Bowel through Uteroenteric Fistula Presenting with Bowel Obstruction after Uterine Fibroid Embolization: Case Report with Histopathologic Correlation.
Pillai AK, Kovoor JM, Reis SP, Kho K, Sutphin PD, Lucas E Journal of vascular and interventional radiology : JVIR 2016 May 27 5 762-4 -
NT-proBNP as a prognostic marker in critically ill patients.
Lucas EA, Wians FH Anesthesia and analgesia 2007 Apr 104 4 998-9; author reply 999-1000
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β-catenin, Pax2, and Pten Panel Identifies Precancers Among Histologically Subdiagnostic Endometrial Lesions.
Research
- Immuno-oncology biomarkers
- Cervical, endometrial, and ovarian carcinoma
- Endometrial precancers
Clinical Focus
- Cytopathology
- Gynecologic Pathology