Hao Chen, M.D., Ph.D.

Pathology
Endometrial Cancer and Precancer
Ovarian Malignancy

Biography

Hao Chen, M.D., Ph.D., is an Assistant Professor in the Department of Pathology at UT Southwestern Medical Center. He specializes in endometrial cancers and precancers, ovarian malignancy, and cervical cancers.

Dr. Chen earned his medical degree at Shandong Medical University and his doctoral degree in immunobiology at the University of Arizona. He completed a residency in pathology at Henry Ford Hospital and the University of Arizona and received advanced training through a gynecological pathology fellowship at UT Southwestern.

Certified by the American Board of Pathology in anatomical pathology and clinical pathology, he joined the UT Southwestern faculty in 2018.

Dr. Chen is a member of the American Society for Clinical Pathology and the United States and Canadian Academy of Pathology. He is also a member of the editorial boards for the International Journal of Surgical Pathology and the World Journal of Hematology and Oncology.

Dr. Chen has delivered international and regional invited lectures, contributed to several books, including Gynecologic and Obstetric Pathology and Diagnostic Endometrial Pathology, and published numerous academic articles related to his areas of expertise.

Education & Training

Medical School - Shandong Medical University, China (1994-1999)
Residency - Henry Ford Health Systems (2013-2014), Pathology
Residency - University of Arizona Medical Center (2014-2017), Pathology
Fellowship - UT Southwestern Medical Center (2017-2018), Gynecologic Pathology

Professional Associations & Affiliations

American Society for Clinical Pathology
United States and Canadian Academy of Pathology

Honors & Awards

Janet Caldwell Award 2018, UT Southwestern Medical Center

Books & Publications

Books
- Probiotic species on cardiovascular disease in Bioactive Food as Dietary Interventions for Cardiovascular Disease
  Chen H, Konhilas JP (2013), Elsevier
- Germ cell tumors and mixed germ cell sex cord-stromal tumors of the ovary in Gynecologic and Obstetric Pathology, Volume 2
  Chen H, Quick CM, Fadare O, Zheng W (2019), Singapore, Springer
- Endometrial premalignant lesions in Diagnostic Endometrial Pathology (2nd ed.)
  Chen H, Zheng W (2019), CRC Press
- Endometrial malignant lesions in Diagnostic Endometrial Pathology (2nd ed.)
  Chen H, Zheng W (2019), CRC Press
- Precursor lesions of endometrial cancer in Gynecologic and Obstetric Pathology (2nd ed.)
  Chen H, Guo D, et al. (2019), Science Press Beijing, Springer
Publications
- 10
- Utility of a PAX2, PTEN, and β-catenin Panel in the Diagnosis of Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia in Endometrial Polyps.
  Lucas E, Niu S, Aguilar M, Molberg K, Carrick K, Rivera-Colon G, Gwin K, Wang Y, Zheng W, Castrillon DH, Chen H, The American journal of surgical pathology 2023 Jun
- Assessment of HER2 in Gastric-Type Endocervical Adenocarcinoma and its Prognostic Significance.
  Wang S, Zhou X, Niu S, Chen L, Zhang H, Chen H, Zhou F, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2023 Jun 36 6 100148
- Morules But Not Squamous Differentiation are a Reliable Indicator of CTNNB1 (?-catenin) Mutations in Endometrial Carcinoma and Precancers.
  Niu S, Lucas E, Molberg K, Strickland A, Wang Y, Carrick K, Rivera-Colon G, Gwin K, SoRelle JA, Castrillon DH, Zheng W, Chen H, The American journal of surgical pathology 2022 10 46 10 1447-1455
- Prevalence and prognostic significance of PD-L1, TIM-3 and B7-H3 expression in endometrial serous carcinoma.
  Chen H, Molberg K, Carrick K, Niu S, Rivera Colon G, Gwin K, Lewis C, Zheng W, Castrillon DH, Lucas E, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2022 Jul
- PD-L1 expression in HPV-independent cervical adenocarcinoma and its prognostic significance.
  Chen L, Lucas E, Zhang X, Liu Q, Zhuang Y, Lin W, Chen H, Zhou F, Histopathology 2021 Aug
- Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers.
  Challa S, Khulpateea BR, Nandu T, Camacho CV, Ryu KW, Chen H, Peng Y, Lea JS, Kraus WL, Cell 2021 Jul
- Serial genomic analysis of endometrium supports the existence of histologically indistinct endometrial cancer precursors.
  Aguilar M, Zhang H, Zhang M, Cantarell B, Sahoo SS, Li HD, Cuevas IC, Lea J, Miller DS, Chen H, Zheng W, Gagan J, Lucas E, Castrillon DH, The Journal of pathology 2021 Jan
- Specific Biomarker Expression Patterns in the Diagnosis of Residual and Recurrent Endometrial Precancers After Progestin Treatment: A Longitudinal Study.
  Chen H, Lucas E, Strickland AL, Carrick K, Gwin K, Castrillon DH, Rivera-Colon G, Niu S, Molberg KH, Zheng W, The American journal of surgical pathology 2020 Oct 44 10 1429-1439
- PD-L1 Expression and CD8+ Tumor-infiltrating Lymphocytes in Different Types of Tubo-Ovarian Carcinoma and Their Prognostic Value in High-grade Serous Carcinoma.
  Chen H, Molberg K, Strickland AL, Castrillon DH, Carrick K, Jiang Q, Niu S, Rivera-Colon G, Gwin K, Hinson S, Lea J, Miller DS, Zheng W, Lucas E, The American journal of surgical pathology 2020 May
- Cervical Adenocarcinoma: Histopathologic Features From Biopsies to Predict Tumor Behavior.
  Rivera-Colon G, Chen H, Niu S, Lucas E, Holloway S, Carrick K, Gwin K, Lea J, Zheng W, The American journal of surgical pathology 2020 Feb 44 2 247-254
- Investigation of antigen-specific T cell receptor clusters in human cancers.
  Li B, Zhang H, Liu L, Zhang J, Chen J, Ye J, Shukla SA, Qiao J, Zhan X, Chen H, Wu CJ, Fu YX, Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Dec
- Effect of Progestin Usage on the Interpretation of Cervical High-grade Squamous Intraepithelial Lesion.
  Wang Y, Chen H, Jiang Q, Luo R, Zhou P, Wang Y, Zhao R, Fadare O, Zheng W, The American journal of surgical pathology 2019 Apr

Research

Endometrial precancers, biomarkers

Clinical Focus

Endometrial Cancer and Precancer
Ovarian Malignancy
Cervical Cancer