Hilda Mirbaha, M.D.

Pathology

Books & Publications

Publications
- Liganded magnetic nanoparticles for magnetic resonance imaging of α-synuclein.
  Pan H, Balbirnie M, Hou K, Sta Maria NS, Sahay S, Denver P, Lepore S, Jones M, Zuo X, Zhu C, Mirbaha H, Shahpasand-Kroner H, Mekkittikul M, Lu J, Hu CJ, Cheng X, Abskharon R, Sawaya MR, Williams CK, Vinters HV, Jacobs RE, Harris NG, Cole GM, Frautschy SA, Eisenberg DS, NPJ Parkinson's disease 2025 Apr 11 1 88
- Cerebellar Vascular Malformation of Unknown Aetiology with Recent COVID-19 Infection.
  Chang D, Tateshima S, Han K, Mirbaha H, Beaman C, Colby GP, Salamon N, Vinters HV, Wang AC, The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2024 Nov 1-4
- Multi-disciplinary team approach for pediatric hemimegalencephaly: Insights from a single institutional case series.
  Edmonds B, Ngo JP, Groves A, Reyes B, Gott RA, Chia DJ, Mirbaha H, Magaki S, Khanlou N, Pineles SL, Salamon N, Thompson RM, Newman M, Rajaraman RR, Hussain SA, Fallah A, Russell B, Nariai H, Epilepsia open 2024 Oct
- HIV and COVID-19: two pandemics with significant (but different) central nervous system complications.
  Magaki S, Zhang T, Han K, Hilda M, Yong WH, Achim C, Fishbein G, Fishbein MC, Garner O, Salamon N, Williams CK, Valdes-Sueiras MA, Hsu JJ, Kelesidis T, Mathisen GE, Lavretsky H, Singer EJ, Vinters HV, Free neuropathology 2024 Jan 5
- Tau seeding in cases of multiple sclerosis.
  LaCroix MS, Mirbaha H, Shang P, Zandee S, Foong C, Prat A, White CL, Stuve O, Diamond MI, Acta neuropathologica communications 2022 Oct 10 1 146
- Seed-competent tau monomer initiates pathology in a tauopathy mouse model.
  Mirbaha H, Chen D, Mullapudi V, Terpack SJ, White CL, Joachimiak LA, Diamond MI, The Journal of biological chemistry 2022 Jun 102163
- Cytoplasmic P53 Immunostaining With N-Terminus P53 Antibody And Absence Of Staining With C-Terminus P53 Antibody: A Report Of Two Pediatric Sarcomas With Distal Truncating TP53 Mutations Affecting Nuclear Localization Domain.
  Mirbaha H, Carrillo D, Mitui M, Hiemenz MC, Singh V, Rakheja D, International journal of surgical pathology 2021 Dec 10668969211065115
- DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation.
  Hou Z, Wydorski PM, Perez VA, Mendoza-Oliva A, Ryder BD, Mirbaha H, Kashmer O, Joachimiak LA, Nature communications 2021 09 12 1 5338
- Site-Specific Hyperphosphorylation Inhibits, Rather than Promotes, Tau Fibrillization, Seeding Capacity, and Its Microtubule Binding.
  Haj-Yahya M, Gopinath P, Rajasekhar K, Mirbaha H, Diamond MI, Lashuel HA, Angewandte Chemie (International ed. in English) 2020 03 59 10 4059-4067
- A synthetic heparinoid blocks tau aggregate cell uptake and amplification.
  Stopschinski BE, Thomas TL, Nadji S, Darvish E, Fan L, Holmes BB, Modi AR, Finnell J, Kashmer OM, Estill-Terpack S, Mirbaha H, Luu HS, Diamond MI, The Journal of biological chemistry 2020 Jan
- Inert and seed-competent tau monomers suggest structural origins of aggregation.
  Mirbaha H, Chen D, Morazova OA, Ruff KM, Sharma AM, Liu X, Goodarzi M, Pappu RV, Colby DW, Mirzaei H, Joachimiak LA, Diamond MI eLife 2018 Jul 7
- Distinct Therapeutic Mechanisms of Tau Antibodies: Promoting Microglial Clearance Versus Blocking Neuronal Uptake.
  Funk KE, Mirbaha H, Jiang H, Holtzman DM, Diamond MI The Journal of biological chemistry 2015 Aug 290 35 21652-62
- Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation.
  Mirbaha H, Holmes BB, Sanders DW, Bieschke J, Diamond MI The Journal of biological chemistry 2015 Jun 290 24 14893-903
- Proteopathic tau seeding predicts tauopathy in vivo.
  Holmes BB, Furman JL, Mahan TE, Yamasaki TR, Mirbaha H, Eades WC, Belaygorod L, Cairns NJ, Holtzman DM, Diamond MI Proceedings of the National Academy of Sciences of the United States of America 2014 Oct 111 41 E4376-85
- Distinct tau prion strains propagate in cells and mice and define different tauopathies.
  Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A, Barker SJ, Foley AC, Thorpe JR, Serpell LC, Miller TM, Grinberg LT, Seeley WW, Diamond MI Neuron 2014 Jun 82 6 1271-88