- Residency - University of Pennsylvania School of Medicine (1983-1988), Pathology/lab Medicine
- Medical School - Washington University School of Medicine (1979-1983)
James Malter, M.D.
- The Senator Betty and Dr. Andy Andujar Distinguished Chairmanship of Pathology
- Pathology
Biography
James Malter, M.D., joined UT Southwestern Medical Center as Professor and Chair of the Department of Pathology in August 2011. He holds The Senator Betty and Dr. Andy Andujar Distinguished Chair in Pathology.
After receiving his undergraduate degree at Dartmouth College, Dr. Malter pursued his medical degree at Washington University School of Medicine in St. Louis. He then completed postdoctoral and residency training in pathology and laboratory medicine at the University of Pennsylvania.
Dr. Malter first became interested in medicine during his senior year at Dartmouth when he was involved on a thesis project at the medical school with a mentor from the Department of Biochemistry. The mentor, a physician/scientist (M.D./Ph.D.), convinced the young Malter that a career in medicine would give him the opportunity to do the science he loved – and more.
In medical school, he would learn the underpinnings of the diseases and conditions he would see in patients, and how he could approach those problems from the development of therapeutics, the investigation of disease mechanisms, or an understanding of the biology and pathology of what he was evaluating.
In 1991, he joined the Department of Pathology and Laboratory Medicine at the University of Wisconsin School of Medicine and Public Health. He was Medical Director of the Blood Bank and Transfusion Service and the Molecular Diagnostics Laboratory for the University of Wisconsin Hospital, and served two years as Acting Chair of the Department of Pathology.
Dr. Malter was named an Investigator at the Waisman Center for Developmental Disabilities, UW Graduate School, in 2002, becoming the Cell and Molecular Neuroscience Core Director in 2003 and Associate Director for Biological Sciences in 2004.
Continuously funded by the National Institutes of Health and other agencies since 1988, Dr. Malter’s research is currently supported by multiple individual and program project grants for his scientific work in post-transcriptional gene regulation and signaling in the immune and nervous systems.
He is a member of both the American Society for Investigative Pathology and the American Society for Clinical Investigation, past Chair of several NIH review panels, and current member of the editorial boards of Journal of Experimental Medicine and Science Signaling.
Meet Dr. Malter
Some say a pathologist is a doctor’s doctor, a primary partner in diagnosing and understanding disease.
James Malter, M.D., Chair of the Department of Pathology at UT Southwestern Medical Center, and his team of 115 pathologists aspire to be just that, delivering the most accurate, well-informed analysis of tissue and body fluids possible to diagnose disease.
“It’s the best patient care we can deliver, when we bring together different doctors with different skill sets and expertise to provide the fastest, most up-to-date, and most accurate diagnosis. That’s what everybody wants, and it’s a tremendous advantage to patients,” says Dr. Malter.
"We can provide a level of expertise in pretty much every area of pathology. That’s a tremendous advantage that our patients receive behind the scenes. They may not realize it, but they’ve got a whole team of experts in their court.”
Dr. Malter oversees three areas: Clinical Pathology, which performs about 14 million laboratory tests each year for patients at UTSW Clinics, University Hospitals, Parkland Memorial Hospital, and Children’s Medical Center; Surgical Pathology, which focuses on tissue analysis for patients at these facilities; and Anatomical Pathology, which includes 15 full-time UTSW medical examiners who perform more than 4,000 autopsies each year at the Dallas County Medical Examiner’s Office. Dr. Malter also manages extensive blood banking and transfusion services.
“Having access to pathology services in an academic medical center is a huge advantage for our patients through the experience and knowledge our pathologists gain by reviewing tens of thousands of samples each year. The most precise diagnosis means the best treatment plan for improving quality of life,” Dr. Malter says.
One of the fascinating areas of pathology and its contribution to clinical care is the continuous evolution and refinement of what makes up specific tissue, like a tumor, he says.
“What makes up this disease process? How are proteins and genes expressed? The deeper we go into these complexities, the more we’re able to discern the differences that exist in individual patients, to understand what will happen to the patient, and whether environmental or hereditary issues are affecting the disease,” Dr. Malter says. “These things all have repercussions on the ultimate outcome, which is to facilitate patient care and provide the highest level of care we can. That’s our goal. That’s what we try to do here.”
Education & Training
Professional Associations & Affiliations
- American Society of Biochemistry and Molecular Biology
- American Society for Investigative Pathology
- American Society for Clinical Investigation
- American Association of Blood Banks
- American Association for the Advancement of Science
Honors & Awards
- Rufus Choate Scholar 1978, Biochemistry - Dartmouth College
- NIH 1986, National Research Service Award
- Outstanding Young Investigator 1987, Academy of Clinical Laboratory Physicians & Scientists
- Nominee 1993, Romnes Fellow, University of Wisconsin, Madison, WI
- Member 1998, American Society for Clinical Investigation
Books & Publications
-
Publications
-
Alzheimer's Disease, Dendritic Spines, and Calcineurin Inhibitors: A New Approach?
O'Neal MA, Stallings NR, Malter JS ACS chemical neuroscience 2018 May -
-induced dendritic spine loss.
Stallings NR, O'Neal MA, Hu J, Kavalali ET, Bezprozvanny I, Malter JS Science signaling 2018 Mar 11 522 -
Pin1 regulates axonal growth cone adhesion and spreading through MARCKS isomerization.
Sosa LJ, Malter JS, Hu J, Bustos Plonka F, Oksdath M, Nieto Guil A, Quiroga S, Pfenninger KH Journal of neurochemistry 2016 Mar -
Phosphate-Induced Renal Fibrosis Requires the Prolyl Isomerase Pin1.
Shen ZJ, Hu J, Shiizaki K, Kuro-O M, Malter JS PloS one 2016 11 2 e0150093 -
The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense.
Hu S, Peng L, Kwak YT, Tekippe EM, Pasare C, Malter JS, Hooper LV, Zaki MH Cell reports 2015 Dec 13 9 1922-36 -
IL-3 Maintains Activation of the p90S6K/RPS6 Pathway and Increases Translation in Human Eosinophils.
Esnault S, Kelly EA, Shen ZJ, Johansson MW, Malter JS, Jarjour NN Journal of immunology (Baltimore, Md. : 1950) 2015 Aug -
XBP1, a determinant of the eosinophil lineage.
Shen ZJ, Malter JS Nature immunology 2015 Jul 16 8 793-4 -
RNA Seq profiling reveals a novel expression pattern of TGF-? target genes in human blood eosinophils.
Shen ZJ, Hu J, Esnault S, Dozmorov I, Malter JS Immunology letters 2015 Jun -
Determinants of eosinophil survival and apoptotic cell death.
Shen ZJ, Malter JS Apoptosis : an international journal on programmed cell death 2015 Feb 20 2 224-34 -
Regulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1.
Shen ZJ, Malter JS Biomolecules 2015 5 2 412-434 -
Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.
Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF Nature communications 2014 2 4802 -
Semaphorin 7A is expressed on airway eosinophils and upregulated by IL-5 family cytokines.
Esnault S, Kelly EA, Johansson MW, Liu LY, Han ST, Akhtar M, Sandbo N, Mosher DF, Denlinger LC, Mathur SK, Malter JS, Jarjour NN Clinical immunology (Orlando, Fla.) 2014 Jan 150 1 90-100 -
Pin1-FADD Interactions Regulate Fas-Mediated Apoptosis in Activated Eosinophils.
Oh J, Malter JS Journal of immunology (Baltimore, Md. : 1950) 2013 Apr -
Identification of genes expressed by human airway eosinophils after an in vivo allergen challenge.
Esnault S, Kelly EA, Schwantes EA, Liu LY, Delain LP, Hauer JA, Bochkov YA, Denlinger LC, Malter JS, Mathur SK, Jarjour NN PloS one 2013 8 7 e67560 -
Soy-based diet exacerbates seizures in mouse models of neurological disease.
Westmark CJ, Westmark PR, Malter JS Journal of Alzheimer's disease : JAD 2013 33 3 797-805 -
Pin1 Null Mice Exhibit Low Bone Mass and Attenuation of BMP Signaling.
Shen ZJ, Hu J, Ali A, Pastor J, Shiizaki K, Blank RD, Kuro-O M, Malter JS PloS one 2013 8 5 e63565 -
The regulation of A?PP expression by RNA-binding proteins.
Westmark CJ, Malter JS Ageing research reviews 2012 Sep 11 4 450-9 -
Pin1 protein regulates Smad protein signaling and pulmonary fibrosis.
Shen ZJ, Braun RK, Hu J, Xie Q, Chu H, Love RB, Stodola LA, Rosenthal LA, Szakaly RJ, Sorkness RL, Malter JS The Journal of biological chemistry 2012 Jul 287 28 23294-305 -
Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function.
Rangasamy V, Mishra R, Sondarva G, Das S, Lee TH, Bakowska JC, Tzivion G, Malter JS, Rana B, Lu KP, Kanthasamy A, Rana A Proceedings of the National Academy of Sciences of the United States of America 2012 May 109 21 8149-54 -
Transforming Growth Factor-?1 Antagonizes Interleukin-5 Pro-Survival Signaling by Activating Calpain-1 in Primary Human Eosinophils.
Xie Q, Shen ZJ, Oh J, Chu H, Malter JS Journal of clinical & cellular immunology 2011 Nov Suppl 1 -
Effect of Anticoagulants on Amyloid ?-Protein Precursor and Amyloid Beta Levels in Plasma.
Westmark CJ, Hervey CM, Berry-Kravis EM, Malter JS Journal of Alzheimer's Disease and Parkinsonism 2011 Jul 1 101 -
Reversal of fragile X phenotypes by manipulation of A?PP/A? levels in Fmr1KO mice.
Westmark CJ, Westmark PR, O'Riordan KJ, Ray BC, Hervey CM, Salamat MS, Abozeid SH, Stein KM, Stodola LA, Tranfaglia M, Burger C, Berry-Kravis EM, Malter JS PloS one 2011 6 10 e26549 -
Preparation of Synaptoneurosomes from Mouse Cortex using a Discontinuous Percoll-Sucrose Density Gradient.
Westmark PR, Westmark CJ, Jeevananthan A, Malter JS Journal of visualized experiments : JoVE 2011 55 -
Plasma exchange after initial intravenous immunoglobulin treatment in Guillain-Barre syndrome: critical reassessment of effectiveness and cost-efficiency.
Oczko-Walker M, Manousakis G, Wang S, Malter JS, Waclawik AJ Journal of clinical neuromuscular disease 2010 Dec 12 2 -
The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils.
Boussetta T, Gougerot-Pocidalo MA, Hayem G, Ciappelloni S, Raad H, Arabi Derkawi R, Bournier O, Kroviarski Y, Zhou XZ, Malter JS, Lu PK, Bartegi A, Dang PM, El-Benna J Blood 2010 Dec 116 26 -
Fragile X Syndrome and Alzheimer's Disease: Another story about APP and beta-amyloid.
Malter JS, Ray BC, Westmark PR, Westmark CJ Current Alzheimer research 2010 May 7 3 -
Pin1 and PKMzeta sequentially control dendritic protein synthesis.
Westmark PR, Westmark CJ, Wang S, Levenson J, O'Riordan KJ, Burger C, Malter JS Science signaling 2010 3 112 -
Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures.
Westmark CJ, Westmark PR, Malter JS Journal of Alzheimer's disease : JAD 2010 20 4 -
The Pin 1 inhibitor juglone attenuates kidney fibrogenesis via Pin 1-independent mechanisms in the unilateral ureteral occlusion model.
Reese S, Vidyasagar A, Jacobson L, Acun Z, Esnault S, Hullett D, Malter JS, Djamali A Fibrogenesis & tissue repair 2010 3 -
N-acetylcysteine prevents 4-hydroxynonenal- and amyloid-beta-induced modification and inactivation of neprilysin in SH-SY5Y cells.
Wang R, Malter JS, Wang DS Journal of Alzheimer's disease : JAD 2010 19 1 -
Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines.
Broytman O, Westmark PR, Gurel Z, Malter JS Neurobiology of aging 2009 Dec 30 12 -
The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.
Shen ZJ, Esnault S, Schinzel A, Borner C, Malter JS Nature immunology 2009 Mar 10 3 -
Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells.
Wang R, Wang S, Malter JS, Wang DS Journal of neurochemistry 2009 Feb 108 4 -
MPEP reduces seizure severity in Fmr-1 KO mice over expressing human Abeta.
Westmark CJ, Westmark PR, Malter JS International journal of clinical and experimental pathology 2009 3 1 -
Effects of 4-hydroxy-nonenal and Amyloid-beta on expression and activity of endothelin converting enzyme and insulin degrading enzyme in SH-SY5Y cells.
Wang R, Wang S, Malter JS, Wang DS Journal of Alzheimer's disease : JAD 2009 17 3 -
Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study.
Young KH, Leroy K, Møller MB, Colleoni GW, Sánchez-Beato M, Kerbauy FR, Haioun C, Eickhoff JC, Young AH, Gaulard P, Piris MA, Oberley TD, Rehrauer WM, Kahl BS, Malter JS, Campo E, Delabie J, Gascoyne RD, Rosenwald A, Rimsza L, Huang J, Braziel RM, Jaffe ES, Wilson WH, Staudt LM, Vose JM, Chan WC, Weisenburger DD, Greiner TC Blood 2008 Oct 112 8 -
Thymic stromal lymphopoietin expression in allergic pulmonary inflammation is Pin1-dependent.
Esnault S, Rosenthal LA, Shen ZJ, Westmark CJ, Sorkness RL, Malter JS The Journal of allergy and clinical immunology 2008 May 121 5 -
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis.
Shen ZJ, Esnault S, Rosenthal LA, Szakaly RJ, Sorkness RL, Westmark PR, Sandor M, Malter JS The Journal of clinical investigation 2008 Feb 118 2 -
Thymic stromal lymphopoietin (TSLP) as a bridge between infection and atopy.
Esnault S, Rosenthal LA, Wang DS, Malter JS International journal of clinical and experimental pathology 2008 1 4 -
Seizure susceptibility and mortality in mice that over-express amyloid precursor protein.
Westmark CJ, Westmark PR, Beard AM, Hildebrandt SM, Malter JS International journal of clinical and experimental pathology 2008 1 2 -
Tissue transglutaminase, protein cross-linking and Alzheimer's disease: review and views.
Wang DS, Dickson DW, Malter JS International journal of clinical and experimental pathology 2008 1 1 -
Pinning down signaling in the immune system: the role of the peptidyl-prolyl isomerase Pin1 in immune cell function.
Esnault S, Shen ZJ, Malter JS Critical reviews in immunology 2008 28 1 -
A critical role for Pin1 in allergic pulmonary eosinophilia in rats.
Esnault S, Rosenthal LA, Shen ZJ, Sedgwick JB, Szakaly RJ, Sorkness RL, Malter JS The Journal of allergy and clinical immunology 2007 Nov 120 5 -
Antisense targeting of TGF-beta1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells.
Shen ZJ, Kim SK, Jun DY, Park W, Kim YH, Malter JS, Moon BJ Experimental cell research 2007 Apr 313 7 -
FMRP mediates mGluR5-dependent translation of amyloid precursor protein.
Westmark CJ, Malter JS PLoS biology 2007 Mar 5 3 -
The significance of Pin1 in the development of Alzheimer's disease.
Wang S, Simon BP, Bennett DA, Schneider JA, Malter JS, Wang DS Journal of Alzheimer's disease : JAD 2007 Mar 11 1 -
Circadian changes in granulocyte-macrophage colony-stimulating factor message in circulating eosinophils.
Esnault S, Fang Y, Kelly EA, Sedgwick JB, Fine J, Malter JS, Jarjour NN Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2007 Jan 98 1 -
Pin1 modulates the type 1 immune response.
Esnault S, Braun RK, Shen ZJ, Xiang Z, Heninger E, Love RB, Sandor M, Malter JS PloS one 2007 2 2 -
The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes.
Esnault S, Shen ZJ, Whitesel E, Malter JS Journal of immunology (Baltimore, Md. : 1950) 2006 Nov 177 10 -
Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells.
Westmark PR, Shin HC, Westmark CJ, Soltaninassab SR, Reinke EK, Malter JS Neurobiology of aging 2006 Jun 27 6 -
beta-Amyloid degradation and Alzheimer's disease.
Wang DS, Dickson DW, Malter JS Journal of biomedicine & biotechnology 2006 2006 3 -
HuR mRNA ligands expressed after seizure.
Westmark CJ, Gourronc FA, Bartleson VB, Sayin U, Bhattacharya S, Sutula T, Malter JS Journal of neuropathology and experimental neurology 2005 Dec 64 12 -
The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils.
Shen ZJ, Esnault S, Malter JS Nature immunology 2005 Dec 6 12 -
RhoB mRNA is stabilized by HuR after UV light.
Westmark CJ, Bartleson VB, Malter JS Oncogene 2005 Jan 24 3 -
Dendritic cell-based immunotherapy for cancer and relevant challenges for transfusion medicine.
Voss CY, Albertini MR, Malter JS Transfusion medicine reviews 2004 Jul 18 3 -
Expression of interleukin-5- and granulocyte macrophage-colony-stimulating factor-responsive genes in blood and airway eosinophils.
Bates ME, Liu LY, Esnault S, Stout BA, Fonkem E, Kung V, Sedgwick JB, Kelly EA, Bates DM, Malter JS, Busse WW, Bertics PJ American journal of respiratory cell and molecular biology 2004 May 30 5 -
Ets-1 regulates TNF-alpha-induced matrix metalloproteinase-9 and tenascin expression in primary bronchial fibroblasts.
Nakamura Y, Esnault S, Maeda T, Kelly EA, Malter JS, Jarjour NN Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 172 3 -
Anti-Abeta: The good, the bad, and the unforeseen.
Broytman O, Malter JS Journal of neuroscience research 2004 Feb 75 3 -
Hyaluronic acid or TNF-alpha plus fibronectin triggers granulocyte macrophage-colony-stimulating factor mRNA stabilization in eosinophils yet engages differential intracellular pathways and mRNA binding proteins.
Esnault S, Malter JS Journal of immunology (Baltimore, Md. : 1950) 2003 Dec 171 12 -
The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95.
Todd PK, Mack KJ, Malter JS Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 100 24 -
Serum and low-density lipoprotein enhance interleukin-8 secretion by airway epithelial cells.
Gern JE, Brockman-Schneider R, Bhattacharya S, Malter JS, Busse WW American journal of respiratory cell and molecular biology 2003 Oct 29 4 -
Whisker stimulation-dependent translation of FMRP in the barrel cortex requires activation of type I metabotropic glutamate receptors.
Todd PK, Malter JS, Mack KJ Brain research. Molecular brain research 2003 Feb 110 2 -
Fragile X mental retardation protein in plasticity and disease.
Todd PK, Malter JS Journal of neuroscience research 2002 Dec 70 5 -
Extracellular signal-regulated kinase mediates granulocyte-macrophage colony-stimulating factor messenger RNA stabilization in tumor necrosis factor-alpha plus fibronectin-activated peripheral blood eosinophils.
Esnault S, Malter JS Blood 2002 Jun 99 11 -
GM-CSF regulation in eosinophils.
Esnault S, Malter JS Archivum immunologiae et therapiae experimentalis 2002 50 2 -
Regulation of mRNA stability in the nervous system and beyond.
Malter JS Journal of neuroscience research 2001 Nov 66 3 -
Y box-binding factor promotes eosinophil survival by stabilizing granulocyte-macrophage colony-stimulating factor mRNA.
Capowski EE, Esnault S, Bhattacharya S, Malter JS Journal of immunology (Baltimore, Md. : 1950) 2001 Nov 167 10 -
Extracellular-regulated kinase controls beta-amyloid precursor protein mRNA decay.
Westmark CJ, Malter JS Brain research. Molecular brain research 2001 Jun 90 2 -
Granulocyte macrophage-colony-stimulating factor mRNA is stabilized in airway eosinophils and peripheral blood eosinophils activated by TNF-alpha plus fibronectin.
Esnault S, Malter JS Journal of immunology (Baltimore, Md. : 1950) 2001 Apr 166 7 -
Granulocyte macrophage colony-stimulating factor and interleukin-5 activate STAT5 and induce CIS1 mRNA in human peripheral blood eosinophils.
Bhattacharya S, Stout BA, Bates ME, Bertics PJ, Malter JS American journal of respiratory cell and molecular biology 2001 Mar 24 3 -
Minute quantities of granulocyte-macrophage colony-stimulating factor prolong eosinophil survival.
Esnault S, Malter JS Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2001 Feb 21 2 -
Up-regulation of nucleolin mRNA and protein in peripheral blood mononuclear cells by extracellular-regulated kinase.
Westmark CJ, Malter JS The Journal of biological chemistry 2001 Jan 276 2 -
Growth factor-mediated stabilization of amyloid precursor protein mRNA is mediated by a conserved 29-nucleotide sequence in the 3'-untranslated region.
Rajagopalan LE, Malter JS Journal of neurochemistry 2000 Jan 74 1 -
Primary peripheral blood eosinophils rapidly degrade transfected granulocyte-macrophage colony-stimulating factor mRNA.
Esnault S, Malter JS Journal of immunology (Baltimore, Md. : 1950) 1999 Nov 163 10 -
Calcium ionophore upregulation of AUUUA-specific binding protein activity is contemporaneous with granulocyte macrophage colony-stimulating factor messenger RNA stabilization in AML14.3D10 cells.
Ruth JH, Esnault S, Jarzembowski JA, Malter JS American journal of respiratory cell and molecular biology 1999 Nov 21 5 -
The 5'-untranslated region of GM-CSF mRNA suppresses translational repression mediated by the 3' adenosine-uridine-rich element and the poly(A) tail.
Jarzembowski JA, Rajagopalan LE, Shin HC, Malter JS Nucleic acids research 1999 Sep 27 18 -
Identification of AUF-1 ligands reveals vast diversity of early response gene mRNAs.
Bhattacharya S, Giordano T, Brewer G, Malter JS Nucleic acids research 1999 Mar 27 6 -
Stabilization of granulocyte-macrophage colony-stimulating factor RNA in a human eosinophil-like cell line requires the AUUUA motifs.
Esnault S, Jarzembowski JA, Malter JS Proceedings of the Association of American Physicians 1998 Nov-Dec 110 6 -
hnRNP C increases amyloid precursor protein (APP) production by stabilizing APP mRNA.
Rajagopalan LE, Westmark CJ, Jarzembowski JA, Malter JS Nucleic acids research 1998 Jul 26 14 -
Posttranscriptional regulation of mRNAs important in T cell function.
Malter JS Advances in immunology 1998 68 -
Pediatric anti-glomerular basement membrane glomerulonephritis.
Trivedi VA, Malter JS, Guillery E Journal of clinical apheresis 1998 13 2 -
Regulation of eukaryotic messenger RNA turnover.
Rajagopalan LE, Malter JS Progress in nucleic acid research and molecular biology 1997 56 -
Cytoplasmic fate of eukaryotic mRNA: identification and characterization of AU-binding proteins.
Jarzembowski JA, Malter JS Progress in molecular and subcellular biology 1997 18 -
Particle-mediated gene transfer of granulocyte-macrophage colony-stimulating factor cDNA to tumor cells: implications for a clinically relevant tumor vaccine.
Mahvi DM, Burkholder JK, Turner J, Culp J, Malter JS, Sondel PM, Yang NS Human gene therapy 1996 Aug 7 13 -
Turnover and translation of in vitro synthesized messenger RNAs in transfected, normal cells.
Rajagopalan LE, Malter JS The Journal of biological chemistry 1996 Aug 271 33 -
In vivo particle-mediated cytokine gene transfer into canine oral mucosa and epidermis.
Keller ET, Burkholder JK, Shi F, Pugh TD, McCabe D, Malter JS, MacEwen EG, Yang NS, Ershler WB Cancer gene therapy 1996 May-Jun 3 3 -
AUUUA-specific mRNA binding proteins in astrocytes.
Jacobs DB, Mandelin AM, Giordano T, Xue I, Malter JS, Singh LD, Snyder AK, Singh SP Life sciences 1996 58 23 -
Granulocyte-macrophage colony-stimulating factor mRNA stabilization enhances transgenic expression in normal cells and tissues.
Rajagopalan LE, Burkholder JK, Turner J, Culp J, Yang NS, Malter JS Blood 1995 Oct 86 7 -
Nucleolin and heterogeneous nuclear ribonucleoprotein C proteins specifically interact with the 3'-untranslated region of amyloid protein precursor mRNA.
Zaidi SH, Malter JS The Journal of biological chemistry 1995 Jul 270 29 -
Post-transcriptional regulation of the p53 tumor suppressor gene during growth-induction of human peripheral blood mononuclear cells.
Voelkerding KV, Steffen DW, Zaidi SH, Malter JS Oncogene 1995 Feb 10 3 -
Multiple proteins interact at a unique cis-element in the 3'-untranslated region of amyloid precursor protein mRNA.
Zaidi SH, Denman R, Malter JS The Journal of biological chemistry 1994 Sep 269 39 -
Modulation of granulocyte-macrophage colony-stimulating factor mRNA stability in vitro by the adenosine-uridine binding factor.
Rajagopalan LE, Malter JS The Journal of biological chemistry 1994 Sep 269 39 -
Amyloid precursor protein mRNA stability is controlled by a 29-base element in the 3'-untranslated region.
Zaidi SH, Malter JS The Journal of biological chemistry 1994 Sep 269 39 -
Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences.
Hamilton BJ, Nagy E, Malter JS, Arrick BA, Rigby WF The Journal of biological chemistry 1993 Apr 268 12 -
Detection of hepatitis C virus RNA sequences by polymerase chain reaction in fixed liver tissue.
Akyol G, Dash S, Shieh YS, Malter JS, Gerber MA Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1992 Sep 5 5 -
Zidovudine-induced blockade of the expression and function of the erythropoietin receptor.
Gogu SR, Malter JS, Agrawal KC Biochemical pharmacology 1992 Sep 44 6 -
EGF cell surface receptor quantitation on ocular cells by an immunocytochemical flow cytometry technique.
Lopez JG, Chew SJ, Thompson HW, Malter JS, Insler MS, Beuerman RW Investigative ophthalmology & visual science 1992 May 33 6 -
Tumor necrosis factor alpha-induced glucose transporter (GLUT-1) mRNA stabilization in 3T3-L1 preadipocytes. Regulation by the adenosine-uridine binding factor.
Stephens JM, Carter BZ, Pekala PH, Malter JS The Journal of biological chemistry 1992 Apr 267 12 -
Regulation of mRNA stability and its relevance to disease.
Carter BZ, Malter JS Laboratory investigation; a journal of technical methods and pathology 1991 Dec 65 6 -
A rapid and inexpensive method for the addition of poly A coding tracts to transcription vectors.
Sullivan D, Malter JS BioTechniques 1991 Nov 11 5 -
Hypoxia up-regulates the activity of a novel erythropoietin mRNA binding protein.
Rondon IJ, MacMillan LA, Beckman BS, Goldberg MA, Schneider T, Bunn HF, Malter JS The Journal of biological chemistry 1991 Sep 266 25 -
Reconstitution of an active surface CD2 by DNA transfer in CD2-CD3+ Jurkat cells facilitates CD3-T cell receptor-mediated IL-2 production.
Makni H, Malter JS, Reed JC, Nobuhiko S, Lang G, Kioussis D, Trinchieri G, Kamoun M Journal of immunology (Baltimore, Md. : 1950) 1991 Apr 146 8 -
Development and application of an in vitro model for screening anti-hepatitis B virus therapeutics.
Lampertico P, Malter JS, Gerber MA Hepatology (Baltimore, Md.) 1991 Mar 13 3 -
A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore.
Malter JS, Hong Y The Journal of biological chemistry 1991 Feb 266 5 -
Flow cytometry measurements of the DNA content of corneal epithelial cells during wound healing.
Thompson HW, Malter JS, Steinemann TL, Beuerman RW Investigative ophthalmology & visual science 1991 Feb 32 2 -
The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.
Gillis P, Malter JS The Journal of biological chemistry 1991 Feb 266 5 -
The polymerase chain reaction for hepatitis B virus DNA.
Malter JS, Gerber MA Hepatology (Baltimore, Md.) 1991 Jan 13 1 -
Detection of CD2 polymorphism on chromosome 1 with EcoRI.
Malter JS, Moolten DN, Alahari SK, Makni H, Kant JA, Kamoun M Nucleic acids research 1990 Nov 18 21 -
Detection of hepatitis B virus DNA in formalin-fixed, paraffin-embedded liver tissue by the polymerase chain reaction.
Lampertico P, Malter JS, Colombo M, Gerber MA The American journal of pathology 1990 Aug 137 2 -
Human papillomavirus type 18 in conjunctival intraepithelial neoplasia.
Lauer SA, Malter JS, Meier JR American journal of ophthalmology 1990 Jul 110 1 -
Adenosine-uridine binding factor requires metals for binding to granulocyte-macrophage colony-stimulating factor mRNA.
Malter JS, McCrory WA, Wilson M, Gillis P Enzyme 1990 44 1-4 -
Regulation of hepatocyte gene expression: progress on the horizon.
Malter JS, Gerber MA Hepatology (Baltimore, Md.) 1989 Dec 10 6 -
Identification of an AUUUA-specific messenger RNA binding protein.
Malter JS Science (New York, N.Y.) 1989 Nov 246 4930 -
Induction and regulation of CD2 mRNA in human lymphocytes.
Malter JS, Reed JC, Kamoun M Journal of immunology (Baltimore, Md. : 1950) 1988 May 140 9 -
Identification of hyperthyroid patients by means of a sensitive assay for thyrotropin.
Malter JS, Manotti SE, Knee GR, Goodman DB, Strauss JF Clinical chemistry 1985 Apr 31 4 -
Role of aminoacylation of histidyl-tRNA in the regulation of protein degradation in Chinese hamster ovary cells.
Scornik OA, Ledbetter ML, Malter JS The Journal of biological chemistry 1980 Jul 255 13
-
Alzheimer's Disease, Dendritic Spines, and Calcineurin Inhibitors: A New Approach?