Kyle Molberg, M.D.

Philip O'Bryan Montgomery Jr., M.D., Professorship in Surgical Pathology

Pathology
Lab Management and Leadership
Mentoring of Junior Faculty

Biography

Kyle Molberg, M.D., is the Philip O’Bryan Montgomery Jr., M.D., Professor of Surgical Pathology in the Department of Pathology at UT Southwestern Medical Center. He has served as Chief of Pathology Services at Parkland Health since 2007 and was President of the Parkland Medical Staff and Chair of the Parkland Medical Executive Committee in 2018 and 2019.

Dr. Molberg earned his medical degree at the UTHealth Houston McGovern Medical School. He completed a residency in anatomic and clinical pathology at Parkland and UT Southwestern, where he also received advanced training in surgical pathology through a fellowship.

Board certified in anatomic and clinical pathology, he joined the UT Southwestern faculty in 1991.

His clinical interests include lab management, leadership, and mentoring of junior faculty. Dr. Molberg has published numerous articles in peer-reviewed journals related to his areas of interest.

Since 2014, Dr. Molberg has been the Course Director and Lecturer for the Introduction to Pathology course for Physician Assistant, Prosthetics and Orthotics, and Physical Therapy students at the UT Southwestern School of Allied Health. He received the UT Southwestern Outstanding Teacher Award for the Medical Student Classes of 2017 and 2018 and the Excellence in Education Outstanding Teacher Award for the Sophomore Pathology Course in 2008 and 2013.

Personal Note

When he’s not working, Dr. Molberg enjoys spending time with his family and dogs, watching college football, particularly his alma mater, SMU, and home landscaping.

Education & Training

Other Post Graduate Training - Intermountain Healthcare, Health Care Delivery Improvement
Medical School - UT Health Science Center McGovern Medical School (1981-1985)
Undergraduate School - Southern Methodist University, Biology
Internship/Residency - UT Southwestern Medical Center (1985-1989), Anatomic & Clinical Pathology
Fellowship - UT Southwestern Medical Center (1989-1990), Surgical Pathology

Professional Associations & Affiliations

Association of Directors of Anatomic and Surgical Pathology
College of American Pathologists
Dallas County Medical Society
Texas Medical Association
Texas Society of Pathologists
United States and Canadian Academy of Pathology

Honors & Awards

Excellence in Education Outstanding Teacher Award, 2008 and 2013, UT Southwestern
UT Southwestern Medical Student Classes of 2017 and 2018 Outstanding Teacher Award

Books & Publications

Publications
- Prevalence and prognostic significance of PD-L1, TIM-3 and B7-H3 expression in endometrial serous carcinoma.
  Chen H, Molberg K, Carrick K, Niu S, Rivera Colon G, Gwin K, Lewis C, Zheng W, Castrillon DH, Lucas E, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2022 Jul
- Morules but Not Squamous Differentiation are a Reliable Indicator of CTNNB1 (?-catenin) Mutations in Endometrial Carcinoma and Precancers.
  Niu S, Lucas E, Molberg K, Strickland A, Wang Y, Carrick K, Rivera-Colon G, Gwin K, SoRelle JA, Castrillon DH, Zheng W, Chen H, The American journal of surgical pathology 2022 Jul
- Significance of Oil-Red-O positive macrophages in bronchoalveolar lavage in diagnosing E-cigarettes or vaping product use-associated lung injury: A case series.
  Niu S, Colon GR, Molberg K, Chen H, Carrick K, Yan S, Sarode V, Lucas E, Diagnostic cytopathology 2021 Jul 49 7 876-884
- PD-L1 Expression in Endocervical Adenocarcinoma: Correlation With Patterns of Tumor Invasion, CD8+ Tumor-infiltrating Lymphocytes, and Clinical Outcomes.
  Rivera-Colon G, Chen H, Molberg K, Niu S, Strickland AL, Castrillon DH, Carrick K, Gwin K, Lea J, Zheng W, Lucas E, The American journal of surgical pathology 2020 Dec
- Specific Biomarker Expression Patterns in the Diagnosis of Residual and Recurrent Endometrial Precancers After Progestin Treatment: A Longitudinal Study.
  Chen H, Lucas E, Strickland AL, Carrick K, Gwin K, Castrillon DH, Rivera-Colon G, Niu S, Molberg KH, Zheng W, The American journal of surgical pathology 2020 Oct 44 10 1429-1439
- PD-L1 Expression and CD8+ Tumor-infiltrating Lymphocytes in Different Types of Tubo-Ovarian Carcinoma and Their Prognostic Value in High-grade Serous Carcinoma.
  Chen H, Molberg K, Strickland AL, Castrillon DH, Carrick K, Jiang Q, Niu S, Rivera-Colon G, Gwin K, Hinson S, Lea J, Miller DS, Zheng W, Lucas E, The American journal of surgical pathology 2020 May
- Association of a Novel Protocol for Rapid Exclusion of Myocardial Infarction With Resource Use in a US Safety Net Hospital.
  Vigen R, Diercks DB, Hashim IA, Pandey A, Zhong L, Kutscher P, Fernandez F, Yu A, Bertulfo B, Molberg K, Metzger JC, Soto J, Alzubaidy D, Thibodeaux L, Joglar JA, Das SR, de Lemos JA, JAMA network open 2020 Apr 3 4 e203359
- Effects of Decalcifying Agents of Variable Duration on PD-L1 Immunohistochemistry.
  Strickland AL, Blacketer S, Molberg K, Markantonis J, Lucas E, American journal of clinical pathology 2020 Jan 153 2 258-265
- Pleomorphic neoplasm in a liver: A potential pitfall for misdiagnosis.
  Alattia L, Molberg K, Lucas E, CytoJournal 2020 17 8
- Comparison of Dako HercepTest and Ventana PATHWAY Anti-HER2 (4B5) Tests and Their Correlation With Fluorescent In Situ Hybridization in Breast Carcinoma.
  Lucas E, Jabbar SB, Molberg K, Fang Y, Xie XJ, Blacketer S, Sahoo S, Applied immunohistochemistry & molecular morphology : AIMM 2019 Jul 27 6 403-409
- Challenges in the Pap diagnosis of endocervical adenocarcinoma in situ.
  Niu S, Molberg K, Thibodeaux J, Rivera-Colon G, Hinson S, Zheng W, Lucas E, Journal of the American Society of Cytopathology 2019 May - Jun 8 3 141-148
- Age cutoff for reporting of benign-appearing endometrial cells in Papanicolaou specimens; should it be raised? A 10-year retrospective study from a large county hospital.
  Hinson S, Molberg K, Mir M, Flores M, Zheng W, Lucas E, Journal of the American Society of Cytopathology 2019 Mar - Apr 8 2 78-83
- Mismatch Repair Protein Expression in Endometrioid Intraepithelial Neoplasia/Atypical Hyperplasia: Should We Screen for Lynch Syndrome in Precancerous Lesions?
  Lucas E, Chen H, Molberg K, Castrillon DH, Rivera Colon G, Li L, Hinson S, Thibodeaux J, Lea J, Miller DS, Zheng W International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2018 Oct
- Evaluation of a Novel Rule-Out Myocardial Infarction Protocol Incorporating High-Sensitivity Troponin T in a US Hospital.
  Vigen R, Kutscher P, Fernandez F, Yu A, Bertulfo B, Hashim IA, Molberg K, Diercks DB, Metzger JC, Soto J, Alzubaidy D, Thibodeaux L, Joglar JA, de Lemos JA, Das SR Circulation 2018 Oct 138 18 2061-2063
- Superficially invasive cervical squamous cell carcinoma metastatic to ovarian endometriotic cyst wall, a case report and brief review of the literature.
  Zhang M, Lucas E, Xiong H, Liu S, Molberg K, Jiang Q, Zheng W Journal of ovarian research 2018 May 11 1 44
- Lung tumor in a young African American patient with sickle trait: Pieces of a puzzle.
  Mir M, Parmley M, Molberg K, Hinson S, Thibodeaux J, Lucas E CytoJournal 2018 15 21
- The diagnostic utility of Merkel cell polyomavirus immunohistochemistry in a fine needle aspirate of metastatic Merkel cell carcinoma of unknown primary to the pancreas.
  Li L, Molberg K, Cheedella N, Thibodeaux J, Hinson S, Lucas E Diagnostic cytopathology 2017 Aug
- Significantly increased PELP1 protein expression in primary and metastatic triple-negative breast carcinoma: comparison with GATA3 expression and PELP1's potential role in triple-negative breast carcinoma.
  Dang DN, Raj G, Sarode V, Molberg KH, Vadlamudi RK, Peng Y Human pathology 2015 Aug
- Decreased androgen receptor expression is associated with distant metastases in patients with androgen receptor-expressing triple-negative breast carcinoma.
  Sutton LM, Cao D, Sarode V, Molberg KH, Torgbe K, Haley B, Peng Y American journal of clinical pathology 2012 Oct 138 4 511-6
- Predictors of invasion and axillary lymph node metastasis in patients with a core biopsy diagnosis of ductal carcinoma in situ: an analysis of 255 cases.
  Han JS, Molberg KH, Sarode V The breast journal 2011 May-Jun 17 3 223-9
- Melanoma in a carcinoma ex pleomorphic adenoma of the parotid gland: a case report and putative histogenesis.
  Karpowicz MK, Shalmon B, Molberg KH, El-Naggar AK Human pathology 2011 Mar 1355-8
- Hormone receptor status rather than HER2 status is significantly associated with increased Ki-67 and p53 expression in triple-negative breast carcinomas, and high expression of Ki-67 but not p53 is significantly associated with axillary nodal metastasis in triple-negative and high-grade non-triple-negative breast carcinomas.
  Han JS, Cao D, Molberg KH, Sarode VR, Rao R, Sutton LM, Peng Y American journal of clinical pathology 2011 Feb 135 2 230-7
- Intratumoral expression level of epidermal growth factor receptor and cytokeratin 5/6 is significantly associated with nodal and distant metastases in patients with basal-like triple-negative breast carcinoma.
  Sutton LM, Han JS, Molberg KH, Sarode VR, Cao D, Rakheja D, Sailors J, Peng Y American journal of clinical pathology 2010 Nov 134 5 782-7
- Diagnostic utility of SALL4 in extragonadal yolk sac tumors: an immunohistochemical study of 59 cases with comparison to placental-like alkaline phosphatase, alpha-fetoprotein, and glypican-3.
  Wang F, Liu A, Peng Y, Rakheja D, Wei L, Xue D, Xue D, Allan RW, Molberg KH, Li J, Cao D The American journal of surgical pathology 2009 Oct 33 10 1529-39
- Cutaneous colocalized invasive poorly differentiated carcinoma and chronic lymphocytic leukemia/small lymphocytic lymphoma of the head and neck region: a case report and review of the literature.
  Peng Y, Wang HY, Molberg KH Archives of otolaryngology--head & neck surgery 2009 Jun 135 6 606-10
- SALL4 is a novel sensitive and specific marker of ovarian primitive germ cell tumors and is particularly useful in distinguishing yolk sac tumor from clear cell carcinoma.
  Cao D, Guo S, Allan RW, Molberg KH, Peng Y The American journal of surgical pathology 2009 Jun 33 6 894-904
- False-positive sentinel lymph nodes in breast cancer patients caused by benign glandular inclusions: report of three cases and review of the literature.
  Peng Y, Ashfaq R, Ewing G, Leitch AM, Molberg KH American journal of clinical pathology 2008 Jul 130 1 21-7; quiz 146
- Primary mucinous adenocarcinoma of the thymus: a case report and review of the literature.
  Kapur P, Rakheja D, Bastasch M, Molberg KH, Sarode VR Archives of pathology & laboratory medicine 2006 Feb 130 2 201-4
- Immunohistochemical expression of beta-catenin in solitary fibrous tumors.
  Rakheja D, Molberg KH, Roberts CA, Jaiswal VR Archives of pathology & laboratory medicine 2005 Jun 129 6 776-9
- Fine needle aspiration cytology of collecting duct carcinoma of the kidney: report of a case with distinctive features and differential diagnosis.
  Sarode VR, Islam S, Wooten D, Watumull LM, Molberg K, Ashfaq R Acta cytologica 2004 Nov-Dec 48 6 843-8
- Secondary syphilis: a histologic and immunohistochemical evaluation.
  Hoang MP, High WA, Molberg KH Journal of cutaneous pathology 2004 Oct 31 9 595-9
- Primary glomangioma of the liver: A case report and review of the literature.
  Jaiswal VR, Champine JG, Sharma S, Molberg KH. Arch Pathol Lab Med March 2004 128(3) 46-49
- Primary glomangioma of the liver: a case report and review of the literature.
  Jaiswal VR, Champine JG, Sharma S, Molberg KH Archives of pathology & laboratory medicine 2004 Mar 128 3 e46-9
- Secondary syphilis: a histologic and immunohistochemical evaluation.
  Hoang MP, High WA, Molberg KH. J Cutan Pathol 2004 31 595-599
- Interpretive disparity among pathologists in breast sentinel lymph node evaluation.
  Roberts CA, Beitsch PD, Litz CE, Hilton DS, Ewing GE, Clifford E, Taylor W, Hapke MR, Babaian A, Khalid I, Hall JD, Lindberg G, Molberg K, Saboorian H American journal of surgery 2003 Oct 186 4 324-9
- Localized retroperitoneal lymphangioleiomyomatosis mimicking malignancy. A case report and review of the literature.
  Jaiswal VR, Baird J, Fleming J, Miller DS, Sharma S, Molberg K Archives of pathology & laboratory medicine 2003 Jul 127 7 879-82
- Interpretative disparity among pathologists in breast sentinel lymph node evaluation.
  Roberts CA, Beitsch PD, Litz CE, Hilton DS, Ewing GE, Clifford E, Taylor W, Hapke MR, Babaian A, Khalid I, Hall, JD, Lindberg G, Molberg K, Saboorian H. Am J Surg Pathol 2003 186(4) 324-329
- Localized retroperitoneal lymphangioleiomyomatosis mimicking malignancy: A case report and review of the literature.
  Jaiswal VR, Baird J, Fleming J, Miller DS, Sharma S, Molberg K. Arch Pathol Lab Med 2003 127(7) 879-882
- Clinicopathologic analysis of CD10+ and CD10- diffuse large B-cell lymphoma. Identification of a high-risk subset with coexpression of CD10 and bcl-2.
  Xu Y, McKenna RW, Molberg KH, Kroft SH American journal of clinical pathology 2001 Aug 116 2 183-90
- Bladder "Mullerianosis" in a woman with lower urinary tract symptoms and hematuria.
  Margulis V, Lemack GE, Molberg K, Saboorian MH The Journal of urology 2001 Jun 165 6 Pt 1 1996-7
- Cutaneous angiosarcoma complicating morbid obesity.
  Azam M, Saboorian H, Bieligk S, Smith T, Molberg K Archives of pathology & laboratory medicine 2001 Apr 125 4 531-3
- Loss of Dpc4 expression in colonic adenocarcinomas correlates with the presence of metastatic disease.
  Maitra A, Molberg K, Albores-Saavedra J, Lindberg G The American journal of pathology 2000 Oct 157 4 1105-11
- Expression of the human mismatch repair gene hMSH2: a potential marker for urothelial malignancy.
  Leach FS, Hsieh JT, Molberg K, Saboorian MH, McConnell JD, Sagalowsky AI Cancer 2000 May 88 10 2333-41
- Endometrioid carcinoma arising in pericecal endometriosis clinically mimicking Crohn's disease.
  Molberg K, Ashfaq R, Gokaslan ST, Shires T Annals of diagnostic pathology 2000 Feb 4 1 29-33
- Loss of Dpc4 expression in colonic adenocarcinomas correlates with the presence of metastatic disease.
  Maitra A, Molberg KH, Albores-Saavedra J, Lindberg G Am J Pathol 2000 157 (4) 1105-1111
- Endometrioid carcinoma arising in pericecal endometriosis clinically mimicking Crohns disease.
  Molberg KH, Ashfaq R, Gokaslan ST, Shires T Ann Diagn Pathol 2000 4 (1) 29-33
- Solitary metastasis of renal cell carcinoma to the contralateral adrenal gland 22 years after nephrectomy
  Sagalowsky Al, Kyle Molberg Urology 1999 54 1 162
- Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and periampullary region.
  Molberg KH, Heffess C, Delgado R, Albores-Saavedra J Cancer 1998 Apr 82 7 1279-87
- Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and periampullary region.
  Molberg KH, Heffess C, Delgado R, Albores-Saavedra J Cancer 1998 82 (7) 1279-1287
- Ectopic prostatic tissue in the uterine cervix.
  Larraza-Hernandez O, Molberg KH, Lindberg G, Albores-Saavedra J International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 1997 Jul 16 3 291-3
- K-ras mutations and allelic loss at 5q and 18q in the development of human pancreatic cancers.
  Sugio K, Molberg K, Albores-Saavedra J, Virmani AK, Kishimoto Y, Gazdar AF International journal of pancreatology : official journal of the International Association of Pancreatology 1997 Jun 21 3 205-17
- Atypical carcinoid of the esophagus: a case report and review of the literature.
  Lindberg GM, Molberg KH, Vuitch MF, Albores-Saavedra J Cancer 1997 Apr 79 8 1476-81
- K-ras mutations and allelic loss of 5q and 18q in the development of human pancreatic cancers.
  Sugio K, Molberg KH, Albores-Saavedra J, Virmani A, Kishimoto Y, Gazdar A. Int J Pancreatology 1997 21(1) 205-217
- Inverted transitional cell papilloma of the uterine cervix
  12. Albores-Saavedra J, Molberg KH Pathology Case Review 1997 2 1 34-37
- Unusual malignant epithelial tumors of the gallbladder.
  Albores-Saavedra J, Molberg K, Henson DE Seminars in diagnostic pathology 1996 Nov 13 4 326-38
- Increased expression of early growth response-1 messenger ribonucleic acid in prostatic adenocarcinoma.
  Thigpen AE, Cala KM, Guileyardo JM, Molberg KH, McConnell JD, Russell DW The Journal of urology 1996 Mar 155 3 975-81
- Physiologic versus neoplastic C-cell hyperplasia of the thyroid: separation of distinct histologic and biologic entities.
  Perry A, Molberg K, Albores-Saavedra J Cancer 1996 Feb 77 4 750-6
- False positive serum prostatic specific antigen values in a patient with non-Hodgkin lymphoma of the kidney
  M.D. Babak Djavan, M.D. Joseph H. Keffer, M.D. Kyle Molberg, M.D. Claus G. Roehrborn Urology 1995 45 5
- Cutaneous endometriosis as a diagnostic pitfall of fine needle aspiration biopsy. A report of three cases.
  Ashfaq R, Molberg KH, Vuitch F Acta cytologica 1994 Jul-Aug 38 4 577-81
- Primary leiomyosarcoma of the seminal vesicle.
  Amirkhan RH, Molberg KH, Wiley EL, Nurenberg P, Sagalowsky AI Urology 1994 Jul 44 1 132-5
- Crystalloids in metastatic prostatic adenocarcinoma.
  Molberg KH, Mikhail A, Vuitch F American journal of clinical pathology 1994 Mar 101 3 266-8
- Hyalinizing trabecular carcinoma of the thyroid gland.
  Molberg K, Albores-Saavedra J Human pathology 1994 Feb 25 2 192-7
- Adrenocortical blastoma.
  Molberg K, Vuitch F, Stewart D, Albores-Saavedra J Human pathology 1992 Oct 23 10 1187-90
- Predictors of residual mass histology following chemotherapy for advanced testis cancer
  M.D. A.I. Sagalowsky, M.D. D.H. Ewalt, M.D. K. Molberg, M.D. R.C. Peters Urology 1990 35 6 537-542
- Paradoxical and pseudoparadoxical interventricular septal motion in patients with right ventricular volume overload.
  Feneley M, Gavaghan T, Circulation 1986 Aug 74 2 230-8

Research

General Surgical Pathology
Hospital and Pathology Administration
Urologic Pathology

Clinical Focus

Lab Management and Leadership
Mentoring of Junior Faculty