- Medical School - Shanxi Medical University (1981-1986)
- Graduate School - Beijing Medical University (1996-1999), Nephrology
- Residency - East Carolina University (2013-2017), Pathology
- Fellowship - UT Southwestern Medical Center (2017-2018), Genitourinary Pathology
- Fellowship - UT Southwestern Medical Center (2018-2019), Renal & Solid Organ Transplant Pathology
- Other Post Graduate Training - Beijing Medical University (1996-1999)
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Qi Cai, M.D., Ph.D.
- Pathology
Education & Training
Books & Publications
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Publications
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Predicting Oncologic Outcomes in Small Renal Tumors.
Kapur P, Zhong H, Araj E, Christie A, Cai Q, Kim D, Miyata J, Tcheuyap VT, Brandenburg O, Carrillo D, Pedrosa I, Brugarolas J, Cadeddu JA, European urology oncology 2022 Sep -
Sensitivity of multiparametric MRI and targeted biopsy for detection of adverse pathologies (Cribriform gleason pattern 4 and intraductal carcinoma): Correlation of detected and missed prostate cancer foci with whole mount histopathology.
Cai Q, Costa DN, Metter CK, Goldberg K, Roehrborn CG, Cadeddu J, Pedrosa I, Meng X, Mostardeiro TR, Shah RB, Urologic oncology 2022 Aug -
De novo or recurrent glomerulonephritis and acute tubulointerstitial nephritis after COVID-19 vaccination: A report of six cases from a single center.
Schaubschlager T, Rajora N, Diep S, Kirtek T, Cai Q, Hendricks AR, Shastri S, Zhou XJ, Saxena R, Clinical nephrology 2022 Feb -
Eosinophilic Vacuolated Tumor of the Kidney: A Review of Evolving Concepts in This Novel Subtype With Additional Insights From a Case With MTOR Mutation and Concomitant Chromosome 1 Loss.
Kapur P, Gao M, Zhong H, Rakheja D, Cai Q, Pedrosa I, Margulis V, Xu L, Kinch L, Brugarolas J, Advances in anatomic pathology 2021 Jul 28 4 251-257 -
Gleason Grade Group Concordance between Preoperative Targeted Biopsy and Radical Prostatectomy Histopathologic Analysis: A Comparison Between In-Bore MRI-guided and MRI-Transrectal US Fusion Prostate Biopsies.
Costa DN, Cai Q, Xi Y, Recchimuzzi DZ, Subramanian N, Bagrodia A, Rofsky NM, Roehrborn CG, Hornberger B, Shah RB, Goldberg K, Diaz de Leon A, Pedrosa I, Radiology. Imaging cancer 2021 03 3 2 e200123 -
Diagnosis of "cribriform" prostatic adenocarcinoma: an interobserver reproducibility study among urologic pathologists with recommendations.
Shah RB, Cai Q, Aron M, Berney DM, Cheville JC, Deng FM, Epstein J, Fine SW, Genega EM, Hirsch MS, Humphrey PA, Gordetsky J, Kristiansen G, Kunju LP, Magi-Galluzzi C, Gupta N, Netto GJ, Osunkoya AO, Robinson BD, Trpkov K, True LD, Troncoso P, Varma M, Wheeler T, Williamson SR, Wu A, Zhou M, American journal of cancer research 2021 11 8 3990-4001 -
Acute interstitial nephritis, a potential predictor of response to immune checkpoint inhibitors in renal cell carcinoma.
Patel V, Elias R, Formella J, Schwartzman W, Christie A, Cai Q, Malladi V, Kapur P, Vazquez M, McKay R, Pedrosa I, Hannan R, Hammers H, Brugarolas J, Journal for immunotherapy of cancer 2020 10 8 2 -
Membranous nephropathy: A ten-year journey of discoveries.
Cai Q, Hendricks AR, Seminars in diagnostic pathology 2020 May 37 3 116-120 -
Upregulation of Endothelial HLA Class II is a Marker of Antibody-Mediated Rejection in Heart Allograft Biopsies.
Cai Q, Moore SA, Hendricks AR, Torrealba JR, Transplantation proceedings 2020 May 52 4 1192-1197 -
Ontological analyses reveal clinically-significant clear cell renal cell carcinoma subtypes with convergent evolutionary trajectories into an aggressive type.
Cai Q, Christie A, Rajaram S, Zhou Q, Araj E, Chintalapati S, Cadeddu J, Margulis V, Pedrosa I, Rakheja D, McKay RM, Brugarolas J, Kapur P, EBioMedicine 2019 Dec -
GPR4 deficiency alleviates intestinal inflammation in a mouse model of acute experimental colitis.
Sanderlin EJ, Leffler NR, Lertpiriyapong K, Cai Q, Hong H, Bakthavatchalu V, Fox JG, Oswald JZ, Justus CR, Krewson EA, O'Rourke D, Yang LV Biochimica et biophysica acta 2016 Dec 1863 2 569-584 -
Rapamycin inhibition of mTORC1 reverses lithium-induced proliferation of renal collecting duct cells.
Gao Y, Romero-Aleshire MJ, Cai Q, Price TJ, Brooks HL, American journal of physiology. Renal physiology 2013 Oct 305 8 F1201-8 -
Phosphorylation of eIF2α via the general control kinase, GCN2, modulates the ability of renal medullary cells to survive high urea stress.
Cai Q, Brooks HL, American journal of physiology. Renal physiology 2011 Dec 301 6 F1202-7 -
Vasopressin increases expression of UT-A1, UT-A3, and ER chaperone GRP78 in the renal medulla of mice with a urinary concentrating defect.
Cai Q, Nelson SK, McReynolds MR, Diamond-Stanic MK, Elliott D, Brooks HL, American journal of physiology. Renal physiology 2010 Oct 299 4 F712-9 -
Vasopressin receptor subtype 2 activation increases cell proliferation in the renal medulla of AQP1 null mice.
Cai Q, McReynolds MR, Keck M, Greer KA, Hoying JB, Brooks HL, American journal of physiology. Renal physiology 2007 Dec 293 6 F1858-64 -
Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause.
Keck M, Romero-Aleshire MJ, Cai Q, Hoyer PB, Brooks HL, American journal of physiology. Renal physiology 2007 Jul 293 1 F193-9 -
Axial heterogeneity of vasopressin-receptor subtypes along the human and mouse collecting duct.
Carmosino M, Brooks HL, Cai Q, Davis LS, Opalenik S, Hao C, Breyer MD American journal of physiology. Renal physiology 2007 Jan 292 1 F351-60 -
Effects of expression of p53 and Gadd45 on osmotic tolerance of renal inner medullary cells.
Cai Q, Dmitrieva NI, Ferraris JD, Michea LF, Salvador JM, Hollander MC, Fornace AJ, Fenton RA, Burg MB, American journal of physiology. Renal physiology 2006 Aug 291 2 F341-9 -
Effects of water restriction on gene expression in mouse renal medulla: identification of 3betaHSD4 as a collecting duct protein.
Cai Q, Keck M, McReynolds MR, Klein JD, Greer K, Sharma K, Hoying JB, Sands JM, Brooks HL, American journal of physiology. Renal physiology 2006 Jul 291 1 F218-24 -
High NaCl increases TonEBP/OREBP mRNA and protein by stabilizing its mRNA.
Cai Q, Ferraris JD, Burg MB, American journal of physiology. Renal physiology 2005 Oct 289 4 F803-7 -
Increased reactive oxygen species contribute to high NaCl-induced activation of the osmoregulatory transcription factor TonEBP/OREBP.
Zhou X, Ferraris JD, Cai Q, Agarwal A, Burg MB, American journal of physiology. Renal physiology 2005 Aug 289 2 F377-85 -
Pax2 expression occurs in renal medullary epithelial cells in vivo and in cell culture, is osmoregulated, and promotes osmotic tolerance.
Cai Q, Dmitrieva NI, Ferraris JD, Brooks HL, van Balkom BW, Burg M, Proceedings of the National Academy of Sciences of the United States of America 2005 Jan 102 2 503-8 -
Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo.
Dmitrieva NI, Cai Q, Burg MB, Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 101 8 2317-22 -
Greater tolerance of renal medullary cells for a slow increase in osmolality is associated with enhanced expression of HSP70 and other osmoprotective genes.
Cai Q, Ferraris JD, Burg MB, American journal of physiology. Renal physiology 2004 Jan 286 1 F58-67 -
Toxicity of acetaminophen, salicylic acid, and caffeine for first-passage rat renal inner medullary collecting duct cells.
Cai Q, Dmitrieva NI, Michea LF, Rocha G, Ferguson D, Burg MB, The Journal of pharmacology and experimental therapeutics 2003 Jul 306 1 35-42 -
Three GADD45 isoforms contribute to hypertonic stress phenotype of murine renal inner medullary cells.
Chakravarty D, Cai Q, Ferraris JD, Michea L, Burg MB, Kültz D, American journal of physiology. Renal physiology 2002 Nov 283 5 F1020-9 -
Rate of increase of osmolality determines osmotic tolerance of mouse inner medullary epithelial cells.
Cai Q, Michea L, Andrews P, Zhang Z, Rocha G, Dmitrieva N, Burg MB, American journal of physiology. Renal physiology 2002 Oct 283 4 F792-8 -
Proliferation and osmotic tolerance of renal inner medullary epithelial cells in vivo and in cell culture.
Zhang Z, Cai Q, Michea L, Dmitrieva NI, Andrews P, Burg MB, American journal of physiology. Renal physiology 2002 Aug 283 2 F302-8
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Predicting Oncologic Outcomes in Small Renal Tumors.