Shirling Tsai, M.D.

Surgery - Vascular Surgery

Biography

Shirling Tsai, M.D., is an Associate Professor in the Department of Surgery at UT Southwestern Medical Center. She specializes in vascular surgery.

Dr. Tsai holds undergraduate degrees in chemistry and physics from Harvard College, where she graduated summa cum laude. She earned her medical degree at Columbia University College of Physicians and Surgeons and completed a residency in general surgery and research fellowship in vascular biology at New York Presbyterian/Weill Cornell Medical Center. She then received advanced training in vascular and endovascular surgery through a fellowship at the Massachusetts General Hospital.

Board certified in general surgery and vascular surgery, Dr. Tsai joined the UT Southwestern faculty in 2012. She also serves as the Chief of Vascular Surgery at the Dallas VA Medical Center.

Dr. Tsai conducts research on the role of lipoprotein receptors in the development of aortic aneurysms and atherosclerosis. Her work has been funded by the American Surgical Association as well as the VA North Texas Health Care Systems New Investigator Program.

She is a member of the Dallas VA Institutional Review Board (IRB), the American College of Surgeons, the Society for Vascular Surgery, the Association for Academic Surgery, the American Heart Association, and the Association of VA Surgeons and is a reviewer for the Journal of Vascular Surgery and the Annals of Vascular Surgery.

Education & Training

Fellowship - Harvard Medical School/Massachusetts General Hospital (2010-2012), Vascular Surgery
Fellowship - Weill Cornell Graduate School of Medical Science (2006-2008), Research
Medical School - Columbia University College of Physicians and Surgeons (1999-2003)
Residency - New York Presbyterian Hospital - Weill Cornell Medical Center (2003-2010), General Surgery

Honors & Awards

D Magazine Best Doctor 2022

Books & Publications

Publications
- Role of Lipoprotein A in Lower Extremity Peripheral Artery Disease.
  Banerjee R, Weideman S, Fernandez-Vazquez D, Banerjee A, Hasan A, Tsai S, The American journal of cardiology 2023 Jul 198 47-49
- Comparative Outcomes of Interventions for Femoropopliteal Chronic Total Occlusion Versus Non-Chronic Total Occlusion Lesions From the Multicenter XLPAD Registry.
  Tsai S, Liu Y, Hoang L, Vu M, Lu H, Ramanan B, Fernandez Vazquez D, Rosol Z, Sayfo S, Alaiti MA, Koutakis P, Brilakis ES, Shishehbor MH, Banerjee S, Journal of the American Heart Association 2023 Jun 12 12 e028425
- Short-Term Outcomes After Retrograde Versus Antegrade Crossing Approaches for Femoropopliteal Occlusive Disease.
  Meadors S, Klein A, Jeon-Slaughter H, Jawaid O, Armstrong EJ, Banerjee R, Alaiti MA, Ramanan B, Modrall JG, Banerjee S, Tsai S, The Journal of invasive cardiology 2023 Jan 35 1 E31-E36
- Current Predictors of Mortality in Veteran Patients Undergoing Major Lower Extremity Amputations: Risk Factors Have Not Changed and Mortality Remains High.
  Tsai S, Lanier HD, Tran N, Pham T, Huerta S, The American surgeon 2022 Feb 31348221074235
- No benefit of vorapaxar on walking performance in patients with intermittent claudication.
  Tsai S, Liu Y, Alaiti MA, Gutierrez JA, Brilakis ES, Banerjee S, Vascular medicine (London, England) 2021 Oct 1358863X211042082
- Effect of Abdominal Aortic Aneurysm Size on Mid-Term Mortality After Endovascular Repair.
  Kim S, Jeon-Slaughter H, Chen X, Ramanan B, Kirkwood ML, Timaran CH, Modrall JG, Tsai S, The Journal of surgical research 2021 Jul 267 443-451
- Reelin Depletion Protects Against Atherosclerosis by Decreasing Vascular Adhesion of Leukocytes.
  Calvier L, Xian X, Lee RG, Sacharidou A, Mineo C, Shaul PW, Kounnas MZ, Tsai S, Herz J, Arteriosclerosis, thrombosis, and vascular biology 2021 04 41 4 1309-1318
- Developing an Internally Validated Veterans Affairs Women Cardiovascular Disease Risk Score Using Veterans Affairs National Electronic Health Records.
  Jeon-Slaughter H, Chen X, Tsai S, Ramanan B, Ebrahimi R, Journal of the American Heart Association 2021 Feb 10 5 e019217
- Coronary and peripheral artery plaques: do differences in plaque characteristics translate to differences in lipid management?
  Tsai S, Vega GL, Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2020 08 68 6 1141-1151
- Rate of Secondary Intervention After Open Versus Endovascular Abdominal Aortic Aneurysm Repair.
  Krishnamoorthi H, Jeon-Slaughter H, Wall A, Banerjee S, Ramanan B, Timaran C, Modrall JG, Tsai S The Journal of surgical research 2018 Dec 232 99-106
- Comparative Assessment of Procedure Cost and Outcomes Between Guidewire and Crossing Device Strategies to Cross Peripheral Artery Chronic Total Occlusions.
  Banerjee S, Jeon-Slaughter H, Tsai S, Mohammad A, Foteh M, Abu-Fadel M, Gigliotti OS, Cawich I, Rodriguez G, Kumbhani D, Addo T, Luna M, Das TS, Prasad A, Armstrong EJ, Shammas NW, Brilakis ES JACC. Cardiovascular interventions 2016 Nov 9 21 2243-2252
- Femoropopliteal Artery Stent Thrombosis: Report From the Excellence in Peripheral Artery Disease Registry.
  Banerjee S, Sarode K, Mohammad A, Gigliotti O, Baig MS, Tsai S, Shammas NW, Prasad A, Abu-Fadel M, Klein A, Armstrong EJ, Jeon-Slaughter H, Brilakis ES, Bhatt DL Circulation. Cardiovascular interventions 2016 Feb 9 2 e002730
- Durability of open repair of juxtarenal abdominal aortic aneurysms.
  Tsai S, Conrad MF, Patel VI, Kwolek CJ, LaMuraglia GM, Brewster DC, Cambria RP Journal of vascular surgery 2012 Jul 56 1 2-7
- Anti-receptor for advanced glycation end products therapies as novel treatment for abdominal aortic aneurysm.
  Zhang F, Kent KC, Yamanouchi D, Zhang Y, Kato K, Tsai S, Nowygrod R, Schmidt AM, Liu B Annals of surgery 2009 Sep 250 3 416-23
- TGF-beta through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation.
  Tsai S, Hollenbeck ST, Ryer EJ, Edlin R, Yamanouchi D, Kundi R, Wang C, Liu B, Kent KC American journal of physiology. Heart and circulatory physiology 2009 Aug 297 2 H540-9
- Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells.
  Zhang F, Tsai S, Kato K, Yamanouchi D, Wang C, Rafii S, Liu B, Kent KC The Journal of biological chemistry 2009 Jun 284 26 17564-74
- Upregulation of protein kinase cdelta in vascular smooth muscle cells promotes inflammation in abdominal aortic aneurysm.
  Schubl S, Tsai S, Ryer EJ, Wang C, Hu J, Kent KC, Liu B The Journal of surgical research 2009 May 153 2 181-7
- The role of progenitor cells in the development of intimal hyperplasia.
  Tsai S, Butler J, Rafii S, Liu B, Kent KC Journal of vascular surgery 2009 Feb 49 2 502-10

Research

Lipoprotein Receptor signaling mechanisms in aortic aneurysm pathogenesis
Genetics of abdominal aortic aneurysms