Sunati Sahoo, M.D.

Harold C. Simmons Comprehensive Cancer Center

Pathology
Breast Cancer
Breast Pathology

Biography

Sunati Sahoo, M.D., is a Professor in the Department of Pathology at UT Southwestern Medical Center. She specializes in the pathology of breast diseases.

Dr. Sahoo earned her medical degree at Sriram Chandra Bhanja Medical College in India and completed postgraduate training in pathology at the All India Institute of Medical Sciences in New Delhi. She performed her residency in pathology at the NewYork-Presbyterian/Weill Cornell Medical Center and received advanced training in breast pathology at NewYork-Presbyterian Hospital, followed by fellowship training in cytopathology at the University of Chicago Medical Center.

Certified by the American Board of Pathology in anatomic and clinical pathology and cytopathology, she joined the UT Southwestern faculty in 2011.

Dr. Sahoo leads the breast pathology services at UT Southwestern and is the Director of Surgical Pathology at UTSW’s William P. Clements Jr. University Hospital. She is a former co-director of the UT Southwestern Tissue Repository at the Harold C. Simmons Comprehensive Cancer Center.

Her research interests include neoadjuvant systemic therapy in breast carcinoma, prognostic and predictive markers of breast carcinoma, and quality and outcome studies in the management of breast disease. She is a Fellow of the College of American Pathologists and a member of the United States and Canadian Academy of Pathology.

The author of numerous articles, monographs, and case studies, Dr. Sahoo has contributed to several books, including chapters in A Comprehensive Guide to Needle Core Biopsies of the Breast, Dabbs Breast Pathology, and Diseases of the Breast.

In 2021, she received UT Southwestern’s Leaders in Clinical Excellence Mentoring Award.

Education & Training

Medical School - Sriram Chandra Bhanja Medical College, India (1986-1991)
Residency - All India Institute of Medical Sciences, India, Anatomic & Clinical Pathology
Residency - Tufts-New England Medical Center (1997-1999), Anatomic & Clinical Pathology
Residency - New York Weil-Cornell Medical Center (1999-2001), Anatomic & Clinical Pathology
Fellowship - University of Chicago Hospital (2001-2002), Surgical Pathology
Fellowship - University of Chicago Hospital (2002-2003), Cytopathology
Fellowship - New York Presbyterian Hospital - Weill Cornell Medical Center (1999-2001), Breast Pathology

Professional Associations & Affiliations

College of American Pathologists
United States and Canadian Academy of Pathology

Honors & Awards

Leaders in Clinical Excellence Mentoring Award 2021, UT Southwestern
Vernie A. Stembridge, MD, Resident Teaching Award in Anatomic Pathology, Department of Pathology 2016, UT Southwestern
Golden Apple Award for Outstanding Faculty Teacher in Pathology 2011, University of Louisville
Service Award in recognition of service and contribution to pathology as the interim director of Anatomic Pathology 2010, University of Louisville
Golden Apple Award for Outstanding Faculty Teacher in Pathology 2006, University of Louisville
Robert Preist Fellowship Award Grant 2002, University of Chicago

Books & Publications

Books
- Invasive lobular carcinoma in A comprehensive guide to needle core biopsies of the breast
  Hwang, H., & Sahoo, S. (2016), New York, Springer
- Lobular neoplasia: Atypical lobular hyperplasia and lobular carcinoma in situ in A comprehensive guide to needle core biopsies of the breast
  Hwang H., & Sahoo, S. (2016), New York, Springer
- Invasive ductal carcinoma including microinvasive carcinoma, tubular carcinoma and cribriform carcinoma in A comprehensive guide to needle core biopsies of the breast
  Saluja K., Hwang H., & Sahoo, S. (2016), New York, Springer
- Pathology of therapeutic response after neoadjuvant therapy in breast cancer in Breast pathology, 2nd ed.
  Sahoo, S., Dabbs, D., & Bhargava, R. (2016), Philadelphia, Elsevier
- Special types of breast carcinoma: Tubular carcinoma, mucinous carcinoma, cribriform carcinoma, invasive micropapillary carcinoma, medullary carcinoma in Breast Pathology, 2nd ed.
  Sahoo, S., & Shin, S. (2016), Philadelphia, Elsevier
- Mimickers of lung carcinoma in cytology and small biopsy material in Diagnosing lung carcinoma on small biopsies and cytology
  Lucas, E., & Sahoo, S. (2015), New York, Springer
- Pathologic assessment of treatment response after neoadjuvant therapy in Diseases of the breast, 5th edition
  Sahoo, S., & Lester, S. C. (2014), Philadelphia, Wolters Kluwer Health
- Pathology of therapeutic response after neoadjuvant therapy in Breast Pathology
  Sahoo, S., Dabbs, D. & Bhargava, R. (2012), Philadelphia, Elsevier
- Special types of breast carcinoma: Tubular carcinoma, mucinous carcinoma, cribriform carcinoma, invasive micropapillary carcinoma, medullary carcinoma. in Breast Pathology
  Sahoo, S., & Shin, S. (2012), Philadelphia, Elsevier
- Pathological considerations in patients treated with neoadjuvant chemotherapy in Breast pathology: Diagnosis and insights in surgical pathology clinics
  Sahoo, S., & Lester, S.C. (2012), Philadelphia, Saunders
- Interpreting breast pathology in the setting of neoadjuvant chemotherapy in Breast surgical techniques and interdisciplinary management
  Sahoo, S., & Lester, S.C. (2011), New York, Springer
Publications
- Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients.
  Yau C, Osdoit M, van der Noordaa M, Shad S, Wei J, de Croze D, Hamy AS, Laé M, Reyal F, Sonke GS, Steenbruggen TG, van Seijen M, Wesseling J, Martín M, Del Monte-Millán M, López-Tarruella S, Boughey JC, Goetz MP, Hoskin T, Gould R, Valero V, Edge SB, Abraham JE, Bartlett JMS, Caldas C, Dunn J, Earl H, Hayward L, Hiller L, Provenzano E, Sammut SJ, Thomas JS, Cameron D, Graham A, Hall P, Mackintosh L, Fan F, Godwin AK, Schwensen K, Sharma P, DeMichele AM, Cole K, Pusztai L, Kim MO, van 't Veer LJ, Esserman LJ, Symmans WF, The Lancet. Oncology 2022 Jan 23 1 149-160
- Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness.
  Parida PK, Marquez-Palencia M, Nair V, Kaushik AK, Kim K, Sudderth J, Quesada-Diaz E, Cajigas A, Vemireddy V, Gonzalez-Ericsson PI, Sanders ME, Mobley BC, Huffman K, Sahoo S, Alluri P, Lewis C, Peng Y, Bachoo RM, Arteaga CL, Hanker AB, DeBerardinis RJ, Malladi S, Cell metabolism 2022 Jan 34 1 90-105.e7
- Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial.
  Symmans WF, Yau C, Chen YY, Balassanian R, Klein ME, Pusztai L, Nanda R, Parker BA, Datnow B, Krings G, Wei S, Feldman MD, Duan X, Chen B, Sattar H, Khazai L, Zeck JC, Sams S, Mhawech-Fauceglia P, Rendi M, Sahoo S, Ocal IT, Fan F, LeBeau LG, Vinh T, Troxell ML, Chien AJ, Wallace AM, Forero-Torres A, Ellis E, Albain KS, Murthy RK, Boughey JC, Liu MC, Haley BB, Elias AD, Clark AS, Kemmer K, Isaacs C, Lang JE, Han HS, Edmiston K, Viscusi RK, Northfelt DW, Khan QJ, Leyland-Jones B, Venters SJ, Shad S, Matthews JB, Asare SM, Buxton M, Asare AL, Rugo HS, Schwab RB, Helsten T, Hylton NM, van 't Veer L, Perlmutter J, DeMichele AM, Yee D, Berry DA, Esserman LJ, JAMA oncology 2021 Sep
- A Phase I/Ib Trial of PD 0332991 (Palbociclib) and T-DM1 in HER2-Positive Advanced Breast Cancer After Trastuzumab and Taxane Therapy.
  Haley B, Batra K, Sahoo S, Froehlich T, Klemow D, Unni N, Ahn C, Rodriguez M, Hullings M, Frankel AE, Clinical breast cancer 2021 Mar
- Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial.
  Yee D, DeMichele AM, Yau C, Isaacs C, Symmans WF, Albain KS, Chen YY, Krings G, Wei S, Harada S, Datnow B, Fadare O, Klein M, Pambuccian S, Chen B, Adamson K, Sams S, Mhawech-Fauceglia P, Magliocco A, Feldman M, Rendi M, Sattar H, Zeck J, Ocal IT, Tawfik O, LeBeau LG, Sahoo S, Vinh T, Chien AJ, Forero-Torres A, Stringer-Reasor E, Wallace AM, Pusztai L, Boughey JC, Ellis ED, Elias AD, Lu J, Lang JE, Han HS, Clark AS, Nanda R, Northfelt DW, Khan QJ, Viscusi RK, Euhus DM, Edmiston KK, Chui SY, Kemmer K, Park JW, Liu MC, Olopade O, Leyland-Jones B, Tripathy D, Moulder SL, Rugo HS, Schwab R, Lo S, Helsten T, Beckwith H, Haugen P, Hylton NM, Van't Veer LJ, Perlmutter J, Melisko ME, Wilson A, Peterson G, Asare AL, Buxton MB, Paoloni M, Clennell JL, Hirst GL, Singhrao R, Steeg K, Matthews JB, Asare SM, Sanil A, Berry SM, Esserman LJ, Berry DA, JAMA oncology 2020 09 6 9 1355-1362
- Comparison of Dako HercepTest and Ventana PATHWAY Anti-HER2 (4B5) Tests and Their Correlation With Fluorescent In Situ Hybridization in Breast Carcinoma.
  Lucas E, Jabbar SB, Molberg K, Fang Y, Xie XJ, Blacketer S, Sahoo S, Applied immunohistochemistry & molecular morphology : AIMM 2019 07 27 6 403-409
- Combined Targeting of Estrogen Receptor Alpha and XPO1 Prevent Akt Activation, Remodel Metabolic Pathways and Induce Autophagy to Overcome Tamoxifen Resistance.
  Kulkoyluoglu-Cotul E, Smith BP, Wrobel K, Zhao YC, Chen KLA, Hieronymi K, Imir OB, Duong K, O'Callaghan C, Mehta A, Sahoo S, Haley B, Chang H, Landesman Y, Madak-Erdogan Z, Cancers 2019 Apr 11 4
- Isolated Contralateral Axillary Lymph Node Involvement in Breast Cancer Represents a Locally Advanced Disease Not Distant Metastases.
  Chkheidze R, Sanders MAG, Haley B, Leitch AM, Sahoo S Clinical breast cancer 2017 Nov
- Pathologic Findings of Breast Lesions Detected on Magnetic Resonance Imaging.
  Jabbar SB, Lynch B, Seiler S, Hwang H, Sahoo S Archives of pathology & laboratory medicine 2017 Aug
- Features of non-mass enhancing lesions detected on 1.5 T breast MRI: A radiologic and pathologic analysis.
  Choudhery S, Lynch B, Sahoo S, J Seiler S Breast disease 2014 Jul
- Pathology Considerations in Patients Treated with Neoadjuvant Chemotherapy.
  Sahoo S, Lester SC Surgical pathology clinics 2012 Sep 5 3 749-74
- Routine prophylactic sentinel lymph node biopsy is not indicated in women undergoing prophylactic mastectomy.
  Czyszczon IA, Roland L, Sahoo S Journal of surgical oncology 2012 Jun 105 7 650-4
- Pathology of breast carcinoma: diagnostic, prognostic, and therapeutic issues and challenges.
  Bhargava R, Sahoo S, Esposito NN, Chen B Pathology research international 2011 2011 731470
- DNA repair signature is associated with anthracycline response in triple negative breast cancer patients.
  Rodriguez AA, Makris A, Wu MF, Rimawi M, Froehlich A, Dave B, Hilsenbeck SG, Chamness GC, Lewis MT, Dobrolecki LE, Jain D, Sahoo S, Osborne CK, Chang JC Breast cancer research and treatment 2010 Aug 123 1 189-96
- Clinical implications of subcategorizing BI-RADS 4 breast lesions associated with microcalcification: a radiology-pathology correlation study.
  Sanders MA, Roland L, Sahoo S The breast journal 2010 Jan-Feb 16 1 28-31
- Pathology of breast carcinomas after neoadjuvant chemotherapy: an overview with recommendations on specimen processing and reporting.
  Sahoo S, Lester SC Archives of pathology & laboratory medicine 2009 Apr 133 4 633-42
- Pathologic evaluation of cryoprobe-assisted lumpectomy for breast cancer.
  Sahoo S, Talwalkar SS, Martin AW, Chagpar AB American journal of clinical pathology 2007 Aug 128 2 239-44
- Coordinate expression of the PI3-kinase downstream effectors serum and glucocorticoid-induced kinase (SGK-1) and Akt-1 in human breast cancer.
  Sahoo S, Brickley DR, Kocherginsky M, Conzen SD European journal of cancer (Oxford, England : 1990) 2005 Nov 41 17 2754-9
- Defining negative margins in DCIS patients treated with breast conservation therapy: The University of Chicago experience.
  Sahoo S, Recant WM, Jaskowiak N, Tong L, Heimann R The breast journal 2005 Jul-Aug 11 4 242-7

Research

Neoadjuvant systemic therapy in breast carcinoma
Prognostic and predictive markers of breast carcinoma
Quality and outcome studies in the management of breast disease

Clinical Focus

Breast Cancer
Breast Pathology
Cytopathology

2021 Leaders in Clinical Excellence

Dr. Sunati Sahoo is the recipient of the 2021 Mentoring Award.