Tania Ortiz Dominguez, M.D.

Psychiatry

Biography

Dr. Ortiz completed her medical training in Mexico and her postgraduate studies at McGill University and Dalhousie University. She is an Associate Professor at the Department of Psychiatry at UT Southwestern, where she leads the Computational Psychiatry Program.

As an expert in bipolar disorder, her research focuses on understanding mood regulation and forecasting episodes of illness using mathematical models and wearable technology.

Dr. Ortiz has been presented with more than 15 awards in her career for her work, including the Samuel Gershon Award by the International Society of Bipolar Disorders and the Clinical Innovator of the Year by Digital Health Canada.

As a principal investigator, she has secured national and international funding from the National Institutes of Mental Health (NIMH), the Canadian Institutes for Health Research (CIHR), and the American Foundation for Suicide Prevention (AFSP).

Professional Associations & Affiliations

International Group for the Study of Lithium (IGSLi) (2023)
Society for Chaos Theory in Psychology and Life Sciences (2022)
Society for Biological Psychiatry (2017)
International Mood Network (2016)
International Society for Bipolar Disorders (2012)
Royal College of Physicians and Surgeons of Canada (2012)
Canadian College of Psychopharmacology (2010)

Honors & Awards

Clinical Innovator of the Year, Digital Health Canada 2023
Samuel Gershon Award for Investigators, International Society for Bipolar Disorders 2016
Best supervisor award, University of Toronto 2024
Academic Scholar Award, University of Toronto 2018
Research Award for Junior Investigators, American Psychiatric Association 2009
Young Psychiatrist Award, World Psychiatric Association 2005
Womenmind Leadership Fund 2022
Society of Biological Psychiatry, Travel Award 2017

Books & Publications

Publications
- Beyond Step Count: Are We Ready to Use Digital Phenotyping to Make Actionable Individual Predictions in Psychiatry?
  Ortiz A, Mulsant BH, Journal of medical Internet research 2024 Aug 26 e59826
- Challenges in defining treatment-resistant mania in adults: A systematic review.
  Gonzalez-Torres C, Mulsant BH, Husain MI, Alda M, Young RC, Ortiz A, Bipolar disorders 2024 Feb 26 1 7-21
- A History of Suicide Attempt Is Associated with Increased Sympathetic Activation in Bipolar Disorder.
  Ortiz A, Park Y, MacLean S, Husain MI, Sanches M, Ravindran A, Mulsant BH, Canadian journal of psychiatry. Revue canadienne de psychiatrie 2024 Feb 69 2 126-137
- The Role of Daily Steps in the Treatment of Major Depressive Disorder: Secondary Analysis of a Randomized Controlled Trial of a 6-Month Internet-Based, Mindfulness-Based Cognitive Behavioral Therapy Intervention for Youth.
  Dang K, Ritvo P, Katz J, Gratzer D, Knyahnytska Y, Ortiz A, Walters C, Attia M, Gonzalez-Torres C, Lustig A, Daskalakis Z, Interactive journal of medical research 2023 Dec 12 e46419
- The Human Phenotype Ontology in 2024: phenotypes around the world.
  Gargano MA, Matentzoglu N, Coleman B, Addo-Lartey EB, Anagnostopoulos AV, Anderton J, Avillach P, Bagley AM, Bakštein E, Balhoff JP, Baynam G, Bello SM, Berk M, Bertram H, Bishop S, Blau H, Bodenstein DF, Botas P, Boztug K, Cady J, Callahan TJ, Cameron R, Carbon SJ, Castellanos F, Caufield JH, Chan LE, Chute CG, Cruz-Rojo J, Dahan-Oliel N, Davids JR, de Dieuleveult M, de Souza V, de Vries BBA, de Vries E, DePaulo JR, Derfalvi B, Dhombres F, Diaz-Byrd C, Dingemans AJM, Donadille B, Duyzend M, Elfeky R, Essaid S, Fabrizzi C, Fico G, Firth HV, Freudenberg-Hua Y, Fullerton JM, Gabriel DL, Gilmour K, Giordano J, Goes FS, Moses RG, Green I, Griese M, Groza T, Gu W, Guthrie J, Gyori B, Hamosh A, Hanauer M, Hanušová K, He YO, Hegde H, Helbig I, Holasová K, Hoyt CT, Huang S, Hurwitz E, Jacobsen JOB, Jiang X, Joseph L, Keramatian K, King B, Knoflach K, Koolen DA, Kraus ML, Kroll C, Kusters M, Ladewig MS, Lagorce D, Lai MC, Lapunzina P, Laraway B, Lewis-Smith D, Li X, Lucano C, Majd M, Marazita ML, Martinez-Glez V, McHenry TH, McInnis MG, McMurry JA, Mihulová M, Millett CE, Mitchell PB, Moslerová V, Narutomi K, Nematollahi S, Nevado J, Nierenberg AA, Cajbiková NN, Nurnberger JI, Ogishima S, Olson D, Ortiz A, Pachajoa H, Perez de Nanclares G, Peters A, Putman T, Rapp CK, Rath A, Reese J, Rekerle L, Roberts AM, Roy S, Sanders SJ, Schuetz C, Schulte EC, Schulze TG, Schwarz M, Scott K, Seelow D, Seitz B, Shen Y, Similuk MN, Simon ES, Singh B, Smedley D, Smith CL, Smolinsky JT, Sperry S, Stafford E, Stefancsik R, Steinhaus R, Strawbridge R, Sundaramurthi JC, Talapova P, Tenorio Castano JA, Tesner P, Thomas RH, Thurm A, Turnovec M, van Gijn ME, Vasilevsky NA, Vlcková M, Walden A, Wang K, Wapner R, Ware JS, Wiafe AA, Wiafe SA, Wiggins LD, Williams AE, Wu C, Wyrwoll MJ, Xiong H, Yalin N, Yamamoto Y, Yatham LN, Yocum AK, Young AH, Yüksel Z, Zandi PP, Zankl A, Zarante I, Zvolský M, Toro S, Carmody LC, Harris NL, Munoz-Torres MC, Danis D, Mungall CJ, Köhler S, Haendel MA, Robinson PN, Nucleic acids research 2023 Nov
- Protocol for a systematic review and meta-analysis of coordinate-based network mapping of brain structure in bipolar disorder across the lifespan.
  Jones BDM, Zhukovsky P, Hawco C, Ortiz A, Cipriani A, Voineskos AN, Mulsant BH, Husain MI, BJPsych open 2023 Oct 9 6 e178
- The futility of long-term predictions in bipolar disorder: mood fluctuations are the result of deterministic chaotic processes.
  Ortiz A, Bradler K, Mowete M, MacLean S, Garnham J, Slaney C, Mulsant BH, Alda M, International journal of bipolar disorders 2021 Oct 9 1 30
- Reduced heart rate variability is associated with higher illness burden in bipolar disorder.
  Ortiz A, Bradler K, Moorti P, MacLean S, Husain MI, Sanches M, Goldstein BI, Alda M, Mulsant BH, Journal of psychosomatic research 2021 Jun 145 110478
- Nonlinear dynamics of mood regulation in unaffected first-degree relatives of bipolar disorder patients.
  A O, K B, J G, C S, S M, M A, Journal of affective disorders 2019 Jan 243 274-279
- Episode forecasting in bipolar disorder: Is energy better than mood?
  Ortiz A, Bradler K, Hintze A, Bipolar disorders 2018 Jan
- Nonlinear dynamics of mood regulation in bipolar disorder.
  Ortiz A, Bradler K, Garnham J, Slaney C, Alda M, Bipolar disorders 2015 Mar 17 2 139-49

Research

Forecasting episodes of illness using mathematical models and wearable technology
Understanding mood regulation

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