Thomas Floyd, M.D.

S.T. "Buddy" Harris Distinguished Chair in Cardiac Anesthesiology

Anesthesiology and Pain Management

Biography

Thomas Floyd, M.D. is a Professor in the Department of Anesthesiology and Pain Management at UT Southwestern Medical Center.

Dr. Floyd earned his medical degree at the University of Pennsylvania School of Medicine and completed a residency in anesthesiology at the University of Minnesota. He received advanced training in magnetic resonance and cardiothoracic anesthesiology through separate fellowships at the University of Pennsylvania.

Certified by the American Board of Anesthesiology and the American Board of Echocardiography, he joined the UT Southwestern faculty in 2017.

Dr. Floyd has served on the scientific advisory board for the Association of University Anesthesiologists. In addition, he is a member of numerous professional organizations, including the Society for Neuroscience, the Society for Neuroanesthesia and Critical Care, the American Heart Association, and the American Society of Anesthesiologists. In 2016, he earned the Faculty Award for Excellence from the Center for Inclusive Education at Stony Brook University.

He has served as principal investigator on several National Institutes of Health-funded research projects, focused primarily on the development and application of imaging technologies and strategies for the early diagnosis and management of neurological sequelae associated with surgery. A second major focus for his laboratory is in understanding the role of hypoxia in aging-associated cognitive failure.

Education & Training

Fellowship - University of Pennsylvania (2000-2001), Cardiothoracic Anesthesiology
Residency - University of Minnesota (1987-1990), Anesthesiology
Internship - University of Minnesota Medical Center (1986-1987), Surgery
Medical School - University of Pennsylvania School of Medicine (1981-1986)

Books & Publications

Publications
- Morbidity and mortality of short-bowel syndrome acquired in infancy: an update.
  Cooper A, Floyd TF, Ross AJ, Bishop HC, Templeton JM, Ziegler MM Journal of pediatric surgery 1984 Dec 19 6 711-8
- Oxygen-sensitive 19F NMR imaging of the vascular system in vivo.
  Fishman JE, Joseph PM, Floyd TF, Mukherji B, Sloviter HA Magnetic resonance imaging 1987 5 4 279-85
- Intestinal ischemia: treatment by peritoneal lavage with oxygenated perfluorochemical.
  Floyd TF, Boroughs A, Garvey C, Dasher J, Ikeda CB, Sloviter HA, Ziegler MM Journal of pediatric surgery 1987 Dec 22 12 1191-7
- Postoperative neurologic assessment and management of the cardiac surgical patient.
  Floyd TF, Cheung AT, Stecker MM Seminars in thoracic and cardiovascular surgery 2000 Oct 12 4 337-48
- Functional MRI and its applications to the clinical neurosciences.
  Detre JA, Floyd TF The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2001 Feb 7 1 64-79
- Precision of the CASL-perfusion MRI technique for the measurement of cerebral blood flow in whole brain and vascular territories.
  Floyd TF, Ratcliffe SJ, Wang J, Resch B, Detre JA Journal of magnetic resonance imaging : JMRI 2003 Dec 18 6 649-55
- Independent cerebral vasoconstrictive effects of hyperoxia and accompanying arterial hypocapnia at 1 ATA.
  Floyd TF, Clark JM, Gelfand R, Detre JA, Ratcliffe S, Guvakov D, Lambertsen CJ, Eckenhoff RG Journal of applied physiology (Bethesda, Md. : 1985) 2003 Dec 95 6 2453-61
- Perioperative changes in cerebral blood flow after cardiac surgery: influence of anemia and aging.
  Floyd TF, McGarvey M, Ochroch EA, Cheung AT, Augoustides JA, Bavaria JE, Acker MA, Pochettino A, Detre JA The Annals of thoracic surgery 2003 Dec 76 6 2037-42
- Major clinical outcomes in adults undergoing thoracic aortic surgery requiring deep hypothermic circulatory arrest: quantification of organ-based perioperative outcome and detection of opportunities for perioperative intervention.
  Augoustides JG, Floyd TF, McGarvey ML, Ochroch EA, Pochettino A, Fulford S, Gambone AJ, Weiner J, Raman S, Savino JS, Bavaria JE, Jobes DR Journal of cardiothoracic and vascular anesthesia 2005 Aug 19 4 446-52
- Rapid and rational echocardiographic-assisted management of cardiogenic shock after coronary artery bypass surgery.
  Augoustides JG, Hosalkar HH, Gambone AJ, Berkowitz D, Floyd TF Journal of cardiothoracic and vascular anesthesia 2005 Dec 19 6 772-4
- Aging: impact upon local cerebral oxygenation and blood flow with acute isovolemic hemodilution.
  Li M, Ratcliffe SJ, Knoll F, Wu J, Ances B, Mardini W, Floyd TF Journal of neurosurgical anesthesiology 2006 Apr 18 2 125-31
- Echocardiography in suspected acute type a aortic dissection: detection and definitive management of a false-positive presentation.
  Augoustides JG, Floyd TF, Kolansky DM Journal of cardiothoracic and vascular anesthesia 2006 Dec 20 6 912-4
- Clinically silent cerebral ischemic events after cardiac surgery: their incidence, regional vascular occurrence, and procedural dependence.
  Floyd TF, Shah PN, Price CC, Harris F, Ratcliffe SJ, Acker MA, Bavaria JE, Rahmouni H, Kuersten B, Wiegers S, McGarvey ML, Woo JY, Pochettino AA, Melhem ER The Annals of thoracic surgery 2006 Jun 81 6 2160-6
- Integrity of the cerebral blood-flow response to hyperoxia after cardiopulmonary bypass.
  Floyd TF, Ratcliffe SJ, Detre JA, Woo YJ, Acker MA, Bavaria JE, Resh BF, Pochettino AA, Eckenhoff RA Journal of cardiothoracic and vascular anesthesia 2007 Apr 21 2 212-7
- Transit delay and flow quantification in muscle with continuous arterial spin labeling perfusion-MRI.
  Wu WC, Wang J, Detre JA, Ratcliffe SJ, Floyd TF Journal of magnetic resonance imaging : JMRI 2008 Aug 28 2 445-52
- Hyperemic flow heterogeneity within the calf, foot, and forearm measured with continuous arterial spin labeling MRI.
  Wu WC, Wang J, Detre JA, Wehrli FW, Mohler E, Ratcliffe SJ, Floyd TF American journal of physiology. Heart and circulatory physiology 2008 May 294 5 H2129-36
- Antiphospholipid syndrome: intraoperative and postoperative anticoagulation in cardiac surgery.
  Weiss S, Nyzio JB, Cines D, Detre J, Milas BL, Narula N, Floyd TF Journal of cardiothoracic and vascular anesthesia 2008 Oct 22 5 735-9
- Accuracy and precision of MR blood oximetry based on the long paramagnetic cylinder approximation of large vessels.
  Langham MC, Magland JF, Epstein CL, Floyd TF, Wehrli FW Magnetic resonance in medicine 2009 Aug 62 2 333-40
- Detection of lactate with a hadamard slice selected, selective multiple quantum coherence, chemical shift imaging sequence (HDMD-SelMQC-CSI) on a clinical MRI scanner: Application to tumors and muscle ischemia.
  Mellon EA, Lee SC, Pickup S, Kim S, Goldstein SC, Floyd TF, Poptani H, Delikatny EJ, Reddy R, Glickson JD Magnetic resonance in medicine 2009 Dec 62 6 1404-13
- Con: Tight perioperative glycemic control.
  Floyd TF, Horak J Journal of cardiothoracic and vascular anesthesia 2009 Dec 23 6 906-8
- Skeletal muscle microvascular flow in progressive peripheral artery disease: assessment with continuous arterial spin-labeling perfusion magnetic resonance imaging.
  Wu WC, Mohler E, Ratcliffe SJ, Wehrli FW, Detre JA, Floyd TF Journal of the American College of Cardiology 2009 Jun 53 25 2372-7
- Retrospective correction for induced magnetic field inhomogeneity in measurements of large-vessel hemoglobin oxygen saturation by MR susceptometry.
  Langham MC, Magland JF, Floyd TF, Wehrli FW Magnetic resonance in medicine 2009 Mar 61 3 626-33
- An organized, comprehensive, and security-enabled strategic response to the Haiti earthquake: a description of pre-deployment readiness preparation and preliminary experience from an academic anesthesiology department with no preexisting international disaster response program.
  McCunn M, Ashburn MA, Floyd TF, Schwab CW, Harrington P, Hanson CW, Sarani B, Mehta S, Speck RM, Fleisher LA Anesthesia and analgesia 2010 Dec 111 6 1438-44
- Evaluation of cuff-induced ischemia in the lower extremity by magnetic resonance oximetry.
  Langham MC, Floyd TF, Mohler ER, Magland JF, Wehrli FW Journal of the American College of Cardiology 2010 Feb 55 6 598-606
- Sex, aging, and preexisting cerebral ischemic disease in patients with aortic stenosis.
  Wang P, Acker MA, Bilello M, Melhem ER, Stambrook E, Ratcliffe SJ, Floyd TF The Annals of thoracic surgery 2010 Oct 90 4 1230-5
- Acute anemia elicits cognitive dysfunction and evidence of cerebral cellular hypoxia in older rats with systemic hypertension.
  Li M, Bertout JA, Ratcliffe SJ, Eckenhoff MF, Simon MC, Floyd TF Anesthesiology 2010 Oct 113 4 845-58
- Rapid magnetic resonance measurement of global cerebral metabolic rate of oxygen consumption in humans during rest and hypercapnia.
  Jain V, Langham MC, Floyd TF, Jain G, Magland JF, Wehrli FW Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011 Jul 31 7 1504-12
- Neurocognitive outcomes in older adults after transcatheter aortic valve replacement.
  Floyd TF, Giovannetti T The Journal of thoracic and cardiovascular surgery 2012 Dec 144 6 1539
- Optical monitoring and detection of spinal cord ischemia.
  Mesquita RC, D'Souza A, Bilfinger TV, Galler RM, Emanuel A, Schenkel SS, Yodh AG, Floyd TF PloS one 2013 8 12 e83370
- Combined measurement of perfusion, venous oxygen saturation, and skeletal muscle T2* during reactive hyperemia in the leg.
  Englund EK, Langham MC, Li C, Rodgers ZB, Floyd TF, Mohler ER, Wehrli FW Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2013 Aug 15 70
- Quantitative CMR markers of impaired vascular reactivity associated with age and peripheral artery disease.
  Langham MC, Englund EK, Mohler ER, Li C, Rodgers ZB, Floyd TF, Wehrli FW Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2013 Feb 15 17
- Vessel-wall imaging and quantification of flow-mediated dilation using water-selective 3D SSFP-echo.
  Langham MC, Li C, Englund EK, Chirico EN, Mohler ER, Floyd TF, Wehrli FW Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2013 Oct 15 100
- Stroke after aortic valve surgery: results from a prospective cohort.
  Messé SR, Acker MA, Kasner SE, Fanning M, Giovannetti T, Ratcliffe SJ, Bilello M, Szeto WY, Bavaria JE, Hargrove WC, Mohler ER, Floyd TF Circulation 2014 Jun 129 22 2253-61
- Multiparametric assessment of vascular function in peripheral artery disease: dynamic measurement of skeletal muscle perfusion, blood-oxygen-level dependent signal, and venous oxygen saturation.
  Englund EK, Langham MC, Ratcliffe SJ, Fanning MJ, Wehrli FW, Mohler ER, Floyd TF Circulation. Cardiovascular imaging 2015 Apr 8 4
- Fiber-optic Monitoring of Spinal Cord Hemodynamics in Experimental Aortic Occlusion.
  Kogler AS, Bilfinger TV, Galler RM, Mesquita RC, Cutrone M, Schenkel SS, Yodh AG, Floyd TF Anesthesiology 2015 Dec 123 6 1362-73
- Rapid High-resolution, Self-registered, Dual Lumen-contrast MRI Method for Vessel-wall Assessment in Peripheral Artery Disease:: A Preliminary Investigation.
  Langham MC, Desjardins B, Englund EK, Mohler ER, Floyd TF, Wehrli FW Academic radiology 2016 Apr 23 4 457-67
- Pathogenesis and Risk Factors for Cerebral Infarct After Surgical Aortic Valve Replacement.
  Massaro A, Messé SR, Acker MA, Kasner SE, Torres J, Fanning M, Giovannetti T, Ratcliffe SJ, Bilello M, Szeto WY, Bavaria JE, Mohler ER, Floyd TF Stroke 2016 Aug 47 8 2130-2
- Measurement of skeletal muscle perfusion dynamics with pseudo-continuous arterial spin labeling (pCASL): Assessment of relative labeling efficiency at rest and during hyperemia, and comparison to pulsed arterial spin labeling (PASL).
  Englund EK, Rodgers ZB, Langham MC, Mohler ER, Floyd TF, Wehrli FW Journal of magnetic resonance imaging : JMRI 2016 Oct 44 4 929-39
- Simultaneous measurement of macro- and microvascular blood flow and oxygen saturation for quantification of muscle oxygen consumption.
  Englund EK, Rodgers ZB, Langham MC, Mohler ER, Floyd TF, Wehrli FW Magnetic resonance in medicine 2017 May
- Effects of Exercise Training on Calf Muscle Oxygen Extraction and Blood Flow in Patients with Peripheral Artery Disease.
  Baker WB, Li Z, Schenkel SS, Chandra M, Busch DR, Englund EK, Schmitz KH, Yodh AG, Floyd TF, Mohler ER Journal of applied physiology (Bethesda, Md. : 1985) 2017 Oct jap.00585.2017
- Laser safety in fiber-optic monitoring of spinal cord hemodynamics: a preclinical evaluation.
  Busch DR, Davis J, Kogler A, Galler RM, Parthasarathy AB, Yodh AG, Floyd TF Journal of biomedical optics 2018 Jun 23 6 1-9
- Recurrence of stroke after cardiac surgery: insight into pathogenesis via diffusion-weighted and continuous arterial spin labeling perfusion magnetic resonance imaging.
  Floyd TF, Harris F, McGarvey M, Detre JA Journal of cardiothoracic and vascular anesthesia 2007 Feb 21 1 106-9
- Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial spin labeled perfusion MRI.
  Yu G, Floyd TF, Durduran T, Zhou C, Wang J, Detre JA, Yodh AG Optics express 2007 Feb 15 3 1064-75