- Medical School - Emory University

Charles Rosenfeld, M.D.
- Pediatrics - Neonatal-Perinatal
Biography
Dr. Rosenfeld attended college at Emory University and graduated from Emory University School of Medicine. He completed his general training in Pediatrics at Yale-New Haven Medical Center and Albert Einstein College of Medicine, where he also was Chief Resident. He then spent a year as a Pediatric Pulmonary Fellow with Amile Scarpelli, MD, PhD at Albert Einstein, followed by 2 years in the Perinatal Research Program at the University of Colorado Health Sciences Center under the mentoring of Frederick Battaglia, MD and Giacomo Meschia, MD. After joining the faculty at UT Southwestern in 1973, Dr. Rosenfeld established a perinatal biology laboratory for the study of cardiovascular changes in pregnancy, and in particular, the study of uteroplacental and umbilicoplacental blood flows. He has received nearly continuous funding from NIH for his studies of the mother and fetus for 39 years, as well as other grants, making contributions to our understanding of cardiovascular changes in pregnancy and during fetal and neonatal development. He was the Director of the Division of Neonatal-Perinatal Medicine for nearly 35 years and has provided research training and mentoring for more than 15 fellows in his specialty, 5 in Maternal-Fetal Medicine, and numerous postdoctoral and medical students. His publication record exceeds 200 peer-reviewed articles and chapters in several textbooks. Dr. Rosenfeld was the 2005 recipient of the Founders Award given by the Southern Society for Pediatric Research for his research contributions to child health and was elected a Fellow in the Section of Heart and Circulatory Physiology, American Physiological Society in 2005.
Education & Training
Professional Associations & Affiliations
- American Physiologic Society (1985)
- American Pediatric Society (1983)
- Society for Gynecologic Investigation (1978)
- American Heart Association (1999)
- Society for Pediatric Research (1977)
- American Pediatric Program Directors (2008)
- Perinatal Research Society (1981)
- American Academy of Pediatrics (1976)
Honors & Awards
- Who's Who in America 2005
- Student Teaching Award, Senior Acute Care Medicine 2008, UT Southwestern Medical School
- Legends Award for Outstanding Service 2007, Parkland Memorial Hospital
- Top Doctors 2012, US News & World Report
- George L. Mac Gregor Professorship of Pediatrics 1993, Recognition for research contributions in Perinatal Medicine
- Associate Editor, Early Human Development 1986, Responsible for all manuscripts in the Americas
- Perinatal Research Society 1981, Recognition for contributions to studies in pregnancy and development
- Associate Editor, Reproductive Sciences (JSGI) 1993, Appointed to the initial Editorial Board; evaluating basic research
- SSPR Founders Award 2005, Recognition for research contributing to improving child health, Southern Society of Pediatric Research
Books & Publications
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Books
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Maternal Cardiovascular Alterations during Pregnancy in Gluckman PS, Heymann MA, eds. Perinatal and Pediatric Pathophysiology: A Clinical Perspective.
Magness RR, Rosenfeld CR. (1993), London: Edward Arnold Publisher. -
Regulation of the Placental Circulation in Polin RA, Abman SH, Rowitch D, Benitz WE, eds. Fetal and Neonatal Physiology. 5th ed.
Rosenfeld CR. (2016), Philadelphia: Elsevier; 114-120. -
Eicosanoids and the Regulation of Uteroplacental Hemodynamics in Mitchell MD, ed. Eicosanoids in Reproduction
Magness RR, Rosenfeld CR. (1990), CRC Press; 139-168.
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Maternal Cardiovascular Alterations during Pregnancy in Gluckman PS, Heymann MA, eds. Perinatal and Pediatric Pathophysiology: A Clinical Perspective.
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Publications
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Fetal-placental crosstalk occurs through fetal cytokine synthesis and placental clearance.
Mir IN, Chalak LF, Liao J, Johnson-Welch S, Brown LS, Longoria C, Savani RC, Rosenfeld CR Placenta 2018 Sep 69 1-8 -
Valid serial length measurements in preterm infants permit characterization of growth patterns.
Pavageau L, Rosenfeld CR, Heyne R, Brown LS, Whitham J, Lair C, Brion LP Journal of perinatology : official journal of the California Perinatal Association 2018 Sep -
Lenticulostriate vasculopathy in preterm infants: a new classification, clinical associations and neurodevelopmental outcome.
Sisman J, Chalak L, Heyne R, Pritchard M, Weakley D, Brown LS, Rosenfeld CR Journal of perinatology : official journal of the California Perinatal Association 2018 Aug -
Extreme Preterm Infant Rates of Overweight and Obesity at School Age in the SUPPORT Neuroimaging and Neurodevelopmental Outcomes Cohort.
Vohr BR, Heyne R, Bann CM, Das A, Higgins RD, Hintz SR The Journal of pediatrics 2018 May -
Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age.
Sarkar S, Shankaran S, Barks J, Do BT, Laptook AR, Das A, Ambalavanan N, Van Meurs KP, Bell EF, Sanchez PJ, Hintz SR, Wyckoff MH, Stoll BJ, Carlo WA The Journal of pediatrics 2018 Feb -
Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation.
Müller JJ, Schwab M, Rosenfeld CR, Antonow-Schlorke I, Nathanielsz PW, Rakers F, Schubert H, Witte OW, Rupprecht S Journal of vascular research 2017 Aug 54 5 259-271 -
Markers of Successful Extubation in Extremely Preterm Infants, and Morbidity After Failed Extubation.
Chawla S, Natarajan G, Shankaran S, Carper B, Brion LP, Keszler M, Carlo WA, Ambalavanan N, Gantz MG, Das A, Finer N, Goldberg RN, Cotten CM, Higgins RD The Journal of pediatrics 2017 Jun -
Patterns of Oxygenation, Mortality, and Growth Status in the Surfactant Positive Pressure and Oxygen Trial Cohort.
Di Fiore JM, Martin RJ, Li H, Morris N, Carlo WA, Finer N, Walsh M The Journal of pediatrics 2017 Mar -
Survival and Neurodevelopmental Outcomes among Periviable Infants.
Younge N, Goldstein RF, Bann CM, Hintz SR, Patel RM, Smith PB, Bell EF, Rysavy MA, Duncan AF, Vohr BR, Das A, Goldberg RN, Higgins RD, Cotten CM The New England journal of medicine 2017 02 376 7 617-628 -
Biomarkers of Adiposity Are Elevated in Preterm Very-Low-Birth-Weight Infants at 1, 2 and 3 Years of Age.
Duncan AF, Frankfurt JA, Heyne RJ, Rosenfeld CR Pediatric research 2017 Jan -
Augmented H2S production via cystathionine-beta-synthase upregulation plays a role in pregnancy-associated uterine vasodilation†.
Sheibani L, Lechuga TJ, Zhang H, Hameed A, Wing DA, Kumar S, Rosenfeld CR, Chen DB Biology of reproduction 2017 Jan -
Growth Outcomes of Preterm Infants Exposed to Different Oxygen Saturation Target Ranges from Birth.
Navarrete CT, Wrage LA, Carlo WA, Walsh MC, Rich W, Gantz MG, Das A, Schibler K, Newman NS, Piazza AJ, Poindexter BB, Shankaran S, Sánchez PJ, Morris BH, Frantz ID, Van Meurs KP, Cotten CM, Ehrenkranz RA, Bell EF, Watterberg KL, Higgins RD, Duara S The Journal of pediatrics 2016 Jun -
Chorioamnionitis and Culture-Confirmed, Early-Onset Neonatal Infections.
Wortham JM, Hansen NI, Schrag SJ, Hale E, Van Meurs K, Sánchez PJ, Cantey JB, Faix R, Poindexter B, Goldberg R, Bizzarro M, Frantz I, Das A, Benitz WE, Shane AL, Higgins R, Stoll BJ Pediatrics 2015 Dec -
Placental Pathology is Associated with Severity of Neonatal Encephalopathy and Adverse Developmental Outcomes following Hypothermia.
Mir IN, Johnson-Welch SF, Nelson DB, Brown LS, Rosenfeld CR, Chalak LF American journal of obstetrics and gynecology 2015 Sep -
Lenticulostriate vasculopathy in neonates: Is it a marker of cerebral insult? Critical review of the literature.
Sisman J, Rosenfeld CR Early human development 2015 Jul 91 7 423-6 -
Lenticulostriate vasculopathy in neonates: Perspective of the radiologist.
Koral K, Sisman J, Pritchard M, Rosenfeld CR Early human development 2015 Jul 91 7 431-5 -
Maternal high fat diet is associated with impaired fetal lung development.
Mayor RS, Finch KE, Zehr J, Morselli E, Neinast MD, Frank AP, Hahner LD, Wang J, Rakheja D, Palmer BF, Rosenfeld CR, Savani RC, Clegg DJ American journal of physiology. Lung cellular and molecular physiology 2015 Jun ajplung.00105.2015 -
Estrogen Replacement Therapy in Ovariectomized Nonpregnant Ewes Stimulates Uterine Artery Hydrogen Sulfide Biosynthesis by Selectively Upregulating Cystathionine ? Synthase Expression.
Lechuga TJ, Zhang H, Sheibani L, Karim M, Jia J, Magness RR, Rosenfeld CR, Chen DB Endocrinology 2015 Mar en20151086 -
Prolonged Uterine Artery Nitric Oxide Synthase Inhibition Modestly Alters Basal Uteroplacental Vasodilation in the Last Third of Ovine Pregnancy.
Rosenfeld CR, Roy T American journal of physiology. Heart and circulatory physiology 2014 Aug -
Biomarkers for severity of neonatal hypoxic-ischemic encephalopathy and outcomes in newborns receiving hypothermia therapy.
Chalak LF, Sánchez PJ, Adams-Huet B, Laptook AR, Heyne RJ, Rosenfeld CR The Journal of pediatrics 2014 Mar 164 3 468-474.e1 -
Serial neutrophil values facilitate predicting the absence of neonatal early-onset sepsis.
Mikhael M, Brown LS, Rosenfeld CR The Journal of pediatrics 2014 Mar 164 3 522-528.e3 -
Neurodevelopmental outcomes of extremely low birth weight infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis.
Wadhawan R, Oh W, Hintz SR, Blakely ML, Das A, Bell EF, Saha S, Laptook AR, Shankaran S, Stoll BJ, Walsh MC, Higgins RD Journal of perinatology : official journal of the California Perinatal Association 2014 Jan 34 1 64-70 -
Immunogenicity of Haemophilus influenzae Type b Protein Conjugate Vaccines in Very Low Birth Weight Infants.
D'Angio CT, Murray TE, Li L, Heyne RJ, O'Shea TM, Schelonka RL, Shankaran S, Duara S, Goldberg RN, Stoll BJ, Stevenson DK, Vohr BR, Phelps DL, Carlo WA, Pichichero ME, Das A, Higgins RD The Pediatric infectious disease journal 2013 Dec 32 12 1400-2 -
Apgar scores at 10 min and outcomes at 6-7 years following hypoxic-ischaemic encephalopathy.
Natarajan G, Shankaran S, Laptook AR, Pappas A, Bann CM, McDonald SA, Das A, Higgins RD, Hintz SR, Vohr BR Archives of disease in childhood. Fetal and neonatal edition 2013 Nov 98 6 F473-9 -
Cerebral palsy and growth failure at 6 to 7 years.
Vohr BR, Stephens BE, McDonald SA, Ehrenkranz RA, Laptook AR, Pappas A, Hintz SR, Shankaran S, Higgins RD, Das A Pediatrics 2013 Oct 132 4 e905-14 -
Association between feeding difficulties and language delay in preterm infants using Bayley Scales of Infant Development-Third Edition.
Adams-Chapman I, Bann CM, Vaucher YE, Stoll BJ The Journal of pediatrics 2013 Sep 163 3 680-5.e1-3 -
Large Conductance Ca2+-Activated K+ Channels Modulate Uterine a1-Adrenergic Sensitivity in Ovine Pregnancy.
Rosenfeld CR, Hynan LS, Liu XT, Roy T Reproductive sciences (Thousand Oaks, Calif.) 2013 Sep -
Individual and Center-Level Factors Affecting Mortality Among Extremely Low Birth Weight Infants.
Alleman BW, Bell EF, Li L, Dagle JM, Smith PB, Ambalavanan N, Laughon MM, Stoll BJ, Goldberg RN, Carlo WA, Murray JC, Cotten CM, Shankaran S, Walsh MC, Laptook AR, Ellsbury DL, Hale EC, Newman NS, Wallace DD, Das A, Higgins RD Pediatrics 2013 Jun -
Ten-Year Review of Major Birth Defects in VLBW Infants.
Adams-Chapman I, Hansen NI, Shankaran S, Bell EF, Boghossian NS, Murray JC, Laptook AR, Walsh MC, Carlo WA, Sánchez PJ, Van Meurs KP, Das A, Hale EC, Newman NS, Ball MB, Higgins RD, Stoll BJ Pediatrics 2013 Jun -
Neurodevelopmental Outcome of Extremely Low Birth Weight Infants with Candida Infection.
Adams-Chapman I, Bann CM, Das A, Goldberg RN, Stoll BJ, Walsh MC, Sánchez PJ, Higgins RD, Shankaran S, Watterberg KL, Duara S, Miller NA, Heyne RJ, Peralta-Carcelen M, Goldstein RF, Steichen JJ, Bauer CR, Hintz SR, Evans PW, Acarregui MJ, Myers GJ, Vohr BR, Wilson-Costello DE, Pappas A, Vaucher YE, Ehrenkranz RA, McGowan EC, Dillard RG, Fuller J, Benjamin DK The Journal of pediatrics 2013 May -
Neurodevelopmental outcomes of extremely low-gestational-age neonates with low-grade periventricular-intraventricular hemorrhage.
Payne AH, Hintz SR, Hibbs AM, Walsh MC, Vohr BR, Bann CM, Wilson-Costello DE JAMA pediatrics 2013 May 167 5 451-9 -
Patent Ductus Arteriosus and Intraventricular Hemorrhage: A Complex Association.
Jaleel MA, Rosenfeld CR The Journal of pediatrics 2013 Mar -
Outcomes of Small for Gestational Age Infants Born at <27 Weeks' Gestation.
De Jesus LC, Pappas A, Shankaran S, Li L, Das A, Bell EF, Stoll BJ, Laptook AR, Walsh MC, Hale EC, Newman NS, Bara R, Higgins RD The Journal of pediatrics 2013 Feb -
Elevated temperature and 6- to 7-year outcome of neonatal encephalopathy.
Laptook AR, McDonald SA, Shankaran S, Stephens BE, Vohr BR, Guillet R, Higgins RD, Das A Annals of neurology 2013 Jan -
Early Sepsis Does Not Increase the Risk of Late Sepsis in Very Low Birth Weight Neonates.
Wynn JL, Hansen NI, Das A, Cotten CM, Goldberg RN, Sánchez PJ, Bell EF, Van Meurs KP, Carlo WA, Laptook AR, Higgins RD, Benjamin DK, Stoll BJ The Journal of pediatrics 2013 Jan -
Influence of gestational age on death and neurodevelopmental outcome in premature infants with severe intracranial hemorrhage.
Goldstein RF, Cotten CM, Shankaran S, Gantz MG, Poole WK Journal of perinatology : official journal of the California Perinatal Association 2013 Jan 33 1 25-32 -
Late-Onset Sepsis in Very Low Birth Weight Infants from Singleton and Multiple-Gestation Births.
Boghossian NS, Page GP, Bell EF, Stoll BJ, Murray JC, Cotten CM, Shankaran S, Walsh MC, Laptook AR, Newman NS, Hale EC, McDonald SA, Das A, Higgins RD The Journal of pediatrics 2013 Jan -
Large conductance Ca2+-activated and voltage-activated K+ channels contribute to the rise and maintenance of estrogen-induced uterine vasodilation and maintenance of blood pressure.
Rosenfeld CR, Roy T Endocrinology 2012 Dec 153 12 6012-20 -
Renal function and systolic blood pressure in very-low-birth-weight infants 1-3 years of age.
Frankfurt JA, Duncan AF, Heyne RJ, Rosenfeld CR Pediatric nephrology (Berlin, Germany) 2012 Dec 27 12 2285-91 -
Empiric antifungal therapy and outcomes in extremely low birth weight infants with invasive candidiasis.
Greenberg RG, Benjamin DK, Gantz MG, Cotten CM, Stoll BJ, Walsh MC, Sánchez PJ, Shankaran S, Das A, Higgins RD, Miller NA, Auten KJ, Walsh TJ, Laptook AR, Carlo WA, Kennedy KA, Finer NN, Duara S, Schibler K, Ehrenkranz RA, Van Meurs KP, Frantz ID, Phelps DL, Poindexter BB, Bell EF, O'Shea TM, Watterberg KL, Goldberg RN, Smith PB The Journal of pediatrics 2012 Aug 161 2 264-9.e2 -
Pregnancy increases myometrial artery myogenic tone via NOS- or COX-independent mechanisms.
Eckman DM, Gupta R, Rosenfeld CR, Morgan TM, Charles SM, Mertz H, Moore LG American journal of physiology. Regulatory, integrative and comparative physiology 2012 Aug 303 4 R368-75 -
Are outcomes of extremely preterm infants improving? Impact of Bayley assessment on outcomes.
Vohr BR, Stephens BE, Higgins RD, Bann CM, Hintz SR, Das A, Newman JE, Peralta-Carcelen M, Yolton K, Dusick AM, Evans PW, Goldstein RF, Ehrenkranz RA, Pappas A, Adams-Chapman I, Wilson-Costello DE, Bauer CR, Bodnar A, Heyne RJ, Vaucher YE, Dillard RG, Acarregui MJ, McGowan EC, Myers GJ, Fuller J The Journal of pediatrics 2012 Aug 161 2 222-8.e3 -
Risk factors for post-neonatal intensive care unit discharge mortality among extremely low birth weight infants.
De Jesus LC, Pappas A, Shankaran S, Kendrick D, Das A, Higgins RD, Bell EF, Stoll BJ, Laptook AR, Walsh MC The Journal of pediatrics 2012 Jul 161 1 70-4.e1-2 -
Approach to infants born at 22 to 24 weeks' gestation: relationship to outcomes of more-mature infants.
Smith PB, Ambalavanan N, Li L, Cotten CM, Laughon M, Walsh MC, Das A, Bell EF, Carlo WA, Stoll BJ, Shankaran S, Laptook AR, Higgins RD, Goldberg RN Pediatrics 2012 Jun 129 6 e1508-16 -
Childhood outcomes after hypothermia for neonatal encephalopathy.
Shankaran S, Pappas A, McDonald SA, Vohr BR, Hintz SR, Yolton K, Gustafson KE, Leach TM, Green C, Bara R, Petrie Huitema CM, Ehrenkranz RA, Tyson JE, Das A, Hammond J, Peralta-Carcelen M, Evans PW, Heyne RJ, Wilson-Costello DE, Vaucher YE, Bauer CR, Dusick AM, Adams-Chapman I, Goldstein RF, Guillet R, Papile LA, Higgins RD The New England journal of medicine 2012 May 366 22 2085-92 -
Methicillin-resistant and susceptible Staphylococcus aureus bacteremia and meningitis in preterm infants.
Shane AL, Hansen NI, Stoll BJ, Bell EF, Sánchez PJ, Shankaran S, Laptook AR, Das A, Walsh MC, Hale EC, Newman NS, Schrag SJ, Higgins RD Pediatrics 2012 Apr 129 4 e914-22 -
Enrollment of extremely low birth weight infants in a clinical research study may not be representative.
Rich W, Finer NN, Gantz MG, Newman NS, Hensman AM, Hale EC, Auten KJ, Schibler K, Faix RG, Laptook AR, Yoder BA, Das A, Shankaran S Pediatrics 2012 Mar 129 3 480-4 -
Outcomes following candiduria in extremely low birth weight infants.
Wynn JL, Tan S, Gantz MG, Das A, Goldberg RN, Adams-Chapman I, Stoll BJ, Shankaran S, Walsh MC, Auten KJ, Miller NA, Sánchez PJ, Higgins RD, Cotten CM, Smith PB, Benjamin DK Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012 Feb 54 3 331-9 -
Differential sensitivity to angiotensin II and norepinephrine in human uterine arteries.
Rosenfeld CR, DeSpain K, Word RA, Liu XT The Journal of clinical endocrinology and metabolism 2012 Jan 97 1 138-47 -
Defining the differential sensitivity to norepinephrine and angiotensin II in the ovine uterine vasculature.
Rosenfeld CR, DeSpain K, Liu XT American journal of physiology. Regulatory, integrative and comparative physiology 2012 Jan 302 1 R59-67 -
Bloodstream infections in very low birth weight infants with intestinal failure.
Cole CR, Hansen NI, Higgins RD, Bell EF, Shankaran S, Laptook AR, Walsh MC, Hale EC, Newman NS, Das A, Stoll BJ The Journal of pediatrics 2012 Jan 160 1 54-9.e2 -
Predictive Value of an Early Amplitude Integrated Electroencephalogram and Neurologic Examination.
Shankaran S, Pappas A, McDonald SA, Laptook AR, Bara R, Ehrenkranz RA, Tyson JE, Goldberg R, Donovan EF, Fanaroff AA, Das A, Poole WK, Walsh M, Higgins RD, Welsh C, Salhab W, Carlo WA, Poindexter B, Stoll BJ, Guillet R, Finer NN, Stevenson DK, Bauer CR Pediatrics 2011 Jul 128 1 e112-20 -
Elevated systolic blood pressure in preterm very-low-birth-weight infants =3 years of life.
Duncan AF, Heyne RJ, Morgan JS, Ahmad N, Rosenfeld CR Pediatric nephrology (Berlin, Germany) 2011 Jul 26 7 1115-21 -
Prediction of Bronchopulmonary Dysplasia by Postnatal Age in Extremely Premature Infants.
Laughon MM, Langer JC, Bose CL, Smith PB, Ambalavanan N, Kennedy KA, Stoll BJ, Buchter S, Laptook AR, Ehrenkranz RA, Cotten CM, Wilson-Costello DE, Shankaran S, Meurs KP, Davis AS, Gantz MG, Finer NN, Yoder BA, Faix RG, Carlo WA, Schibler KR, Newman NS, Rich W, Das A, Higgins RD, Walsh MC American journal of respiratory and critical care medicine 2011 Jun 183 12 1715-22 -
Metabolic imprinting by prenatal, perinatal, and postnatal overnutrition: a review.
Dyer JS, Rosenfeld CR Seminars in reproductive medicine 2011 May 29 3 266-76 -
Early-childhood neurodevelopmental outcomes are not improving for infants born at <25 weeks' gestational age.
Hintz SR, Kendrick DE, Wilson-Costello DE, Das A, Bell EF, Vohr BR, Higgins RD Pediatrics 2011 Jan 127 1 62-70 -
Intercenter differences in bronchopulmonary dysplasia or death among very low birth weight infants.
Ambalavanan N, Walsh M, Bobashev G, Das A, Levine B, Carlo WA, Higgins RD Pediatrics 2011 Jan 127 1 e106-16 -
Prenatal closure of the ductus arteriosus and maternal ingestion of anthocyanins.
Kapadia V, Embers D, Wells E, Lemler M, Rosenfeld CR Journal of perinatology : official journal of the California Perinatal Association 2010 Apr 30 4 291-4 -
Regulation of the cGMP-cPKG pathway and large-conductance Ca2+-activated K+ channels in uterine arteries during the ovine ovarian cycle.
Khan LH, Rosenfeld CR, Liu XT, Magness RR American journal of physiology. Endocrinology and metabolism 2010 Feb 298 2 E222-8 -
Pregnancy modifies the large conductance Ca2+-activated K+ channel and cGMP-dependent signaling pathway in uterine vascular smooth muscle.
Rosenfeld CR, Liu XT, DeSpain K American journal of physiology. Heart and circulatory physiology 2009 Jun 296 6 H1878-87 -
Maternal age, multiple birth, and extremely low birth weight infants.
Vohr BR, Tyson JE, Wright LL, Perritt RL, Li L, Poole WK The Journal of pediatrics 2009 Apr 154 4 498-503.e2 -
Metabolism and synthesis of arginine vasopressin in conscious newborn sheep.
Miao DC, Velaphi SC, Roy T, Despain K, Rosenfeld CR American journal of physiology. Endocrinology and metabolism 2008 Sep 295 3 E672-7 -
Interrater reliability and effect of state on blood pressure measurements in infants 1 to 3 years of age.
Duncan AF, Rosenfeld CR, Morgan JS, Ahmad N, Heyne RJ Pediatrics 2008 Sep 122 3 e590-4 -
Large conductance Ca2+-activated K+ channels contribute to vascular function in nonpregnant human uterine arteries.
Rosenfeld CR, Word RA, DeSpain K, Liu XT Reproductive sciences (Thousand Oaks, Calif.) 2008 Sep 15 7 651-60 -
Meconium increases type 1 angiotensin II receptor expression and alveolar cell death.
Rosenfeld CR, Zagariya AM, Liu XT, Willis BC, Fluharty S, Vidyasagar D Pediatric research 2008 Mar 63 3 251-6 -
Insulin resistance in Hispanic large-for-gestational-age neonates at birth.
Dyer JS, Rosenfeld CR, Rice J, Rice M, Hardin DS The Journal of clinical endocrinology and metabolism 2007 Oct 92 10 3836-43 -
Vascular development in early ovine gestation: carotid smooth muscle function, phenotype, and biochemical markers.
Hutanu C, Cox BE, DeSpain K, Liu XT, Rosenfeld CR American journal of physiology. Regulatory, integrative and comparative physiology 2007 Jul 293 1 R323-33 -
The renin-angiotensin system in conscious newborn sheep: metabolic clearance rate and activity.
Velaphi SC, Despain K, Roy T, Rosenfeld CR Pediatric research 2007 Jun 61 6 681-6 -
Prevalence of spontaneous closure of the ductus arteriosus in neonates at a birth weight of 1000 grams or less.
Koch J, Hensley G, Roy L, Brown S, Ramaciotti C, Rosenfeld CR Pediatrics 2006 Apr 117 4 1113-21 -
Estrogen regulates {beta}1-subunit expression in Ca(2+)-activated K(+) channels in arteries from reproductive tissues.
Nagar D, Liu XT, Rosenfeld CR American journal of physiology. Heart and circulatory physiology 2005 Oct 289 4 H1417-27 -
Large-conductance Ca2+-dependent K+ channels regulate basal uteroplacental blood flow in ovine pregnancy.
Rosenfeld CR, Roy T, DeSpain K, Cox BE Journal of the Society for Gynecologic Investigation 2005 Sep 12 6 402-8 -
Effects of systemic and local phenylephrine and arginine vasopressin infusions in conscious postnatal sheep.
Velaphi SC, Roy T, Despain K, Rosenfeld CR Pediatric research 2005 Jul 58 1 58-65 -
Vessel-specific regulation of angiotensin II receptor subtypes during ovine development.
Cox BE, Liu XT, Fluharty SJ, Rosenfeld CR Pediatric research 2005 Jan 57 1 124-32 -
Angiotensin II mediates uterine vasoconstriction through alpha-stimulation.
Cox BE, Roy TA, Rosenfeld CR American journal of physiology. Heart and circulatory physiology 2004 Jul 287 1 H126-34 -
Hospital survival of very-low-birth-weight neonates from 1977 to 2000.
Kaiser JR, Tilford JM, Simpson PM, Salhab WA, Rosenfeld CR Journal of perinatology : official journal of the California Perinatal Association 2004 Jun 24 6 343-50 -
Are complete blood cell counts useful in the evaluation of asymptomatic neonates exposed to suspected chorioamnionitis?
Jackson GL, Engle WD, Sendelbach DM, Vedro DA, Josey S, Vinson J, Bryant C, Hahn G, Rosenfeld CR Pediatrics 2004 May 113 5 1173-80 -
Estrogen selectively up-regulates eNOS and nNOS in reproductive arteries by transcriptional mechanisms.
Rosenfeld CR, Chen C, Roy T, Liu X Journal of the Society for Gynecologic Investigation 2003 May 10 4 205-15 -
Differential responses to systemic and local angiotensin II infusions in conscious postnatal sheep.
Velaphi SC, Roy T, Despain K, Rosenfeld CR Pediatric research 2002 Sep 52 3 333-41 -
Mechanisms modulating estrogen-induced uterine vasodilation.
Rosenfeld CR, Roy T, Cox BE Vascular pharmacology 2002 Feb 38 2 115-25 -
Ca(2+)-activated K(+) channels modulate basal and E(2)beta-induced rises in uterine blood flow in ovine pregnancy.
Rosenfeld CR, Cornfield DN, Roy T American journal of physiology. Heart and circulatory physiology 2001 Jul 281 1 H422-31 -
Maturation of ovine uterine smooth muscle during development and the effects of parity.
Arens Y, Kamm KE, Rosenfeld CR Journal of the Society for Gynecologic Investigation 2000 Sep-Oct 7 5 284-90 -
Determinants of blood pressure in very low birth weight neonates: lack of effect of antenatal steroids.
LeFlore JL, Engle WD, Rosenfeld CR Early human development 2000 Jul 59 1 37-50 -
Calcium-activated potassium channels and nitric oxide coregulate estrogen-induced vasodilation.
Rosenfeld CR, White RE, Roy T, Cox BE American journal of physiology. Heart and circulatory physiology 2000 Jul 279 1 H319-28 -
Regulation of types I and III NOS in ovine uterine arteries by daily and acute estrogen exposure.
Salhab WA, Shaul PW, Cox BE, Rosenfeld CR American journal of physiology. Heart and circulatory physiology 2000 Jun 278 6 H2134-42 -
Maturational differences between vascular and bladder smooth muscle during ovine development.
Arens YH, Rosenfeld CR, Kamm KE American journal of physiology. Regulatory, integrative and comparative physiology 2000 May 278 5 R1305-13 -
Angiotensin II indirectly vasoconstricts the ovine uterine circulation.
Cox BE, Williams CE, Rosenfeld CR American journal of physiology. Regulatory, integrative and comparative physiology 2000 Feb 278 2 R337-44 -
A population-based study of congenital diaphragmatic hernia: impact of associated anomalies and preoperative blood gases on survival.
Kaiser JR, Rosenfeld CR Journal of pediatric surgery 1999 Aug 34 8 1196-202 -
Ontogeny of vascular angiotensin II receptor subtype expression in ovine development.
Cox BE, Rosenfeld CR Pediatric research 1999 Mar 45 3 414-24 -
Differential development of umbilical and systemic arteries. II. Contractile proteins.
Arens Y, Chapados RA, Cox BE, Kamm KE, Rosenfeld CR The American journal of physiology 1998 Jun 274 6 Pt 2 R1815-23 -
Differential development of umbilical and systemic arteries. I. ANG II receptor subtype expression.
Kaiser JR, Cox BE, Roy TA, Rosenfeld CR The American journal of physiology 1998 Mar 274 3 Pt 2 R797-807 -
Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium.
Lantin-Hermoso RL, Rosenfeld CR, Yuhanna IS, German Z, Chen Z, Shaul PW The American journal of physiology 1997 Jul 273 1 Pt 1 L119-26 -
Circulating neutrophils in septic preterm neonates: comparison of two reference ranges.
Engle WD, Rosenfeld CR, Mouzinho A, Risser RC, Zeray F, Sanchez PJ Pediatrics 1997 Mar 99 3 E10 -
Nitric oxide contributes to estrogen-induced vasodilation of the ovine uterine circulation.
Rosenfeld CR, Cox BE, Roy T, Magness RR The Journal of clinical investigation 1996 Nov 98 9 2158-66 -
Brain does not utilize low density lipoprotein-cholesterol during fetal and neonatal development in the sheep.
Turley SD, Burns DK, Rosenfeld CR, Dietschy JM Journal of lipid research 1996 Sep 37 9 1953-61 -
Alterations in myometrial stress during ovine pregnancy and the puerperium.
Ipson MA, Rosenfeld CR, Magness RR, Kamm KE The American journal of physiology 1996 Aug 271 2 Pt 2 R446-54 -
Tissue specific expression of vascular smooth muscle angiotensin II receptor subtypes during ovine pregnancy.
Cox BE, Rosenfeld CR, Kalinyak JE, Magness RR, Shaul PW The American journal of physiology 1996 Jul 271 1 Pt 2 H212-21 -
Endothelial vasodilator production by uterine and systemic arteries. I. Effects of ANG II on PGI2 and NO in pregnancy.
Magness RR, Rosenfeld CR, Hassan A, Shaul PW The American journal of physiology 1996 Jun 270 6 Pt 2 H1914-23 -
Angiotensin II receptor characteristics and subtype expression in uterine arteries and myometrium during pregnancy.
Cox BE, Word RA, Rosenfeld CR The Journal of clinical endocrinology and metabolism 1996 Jan 81 1 49-58 -
The small for gestational age infant: accelerated or delayed pulmonary maturation? Increased or decreased survival?
Tyson JE, Kennedy K, Broyles S, Rosenfeld CR Pediatrics 1995 Apr 95 4 534-8 -
Comparison of ANG II in fetal and pregnant sheep: metabolic clearance and vascular sensitivity.
Rosenfeld CR, Gresores A, Roy TA, Magness RR The American journal of physiology 1995 Feb 268 2 Pt 1 E237-47 -
Surfactant protein A and saturated phosphatidylcholine in respiratory distress syndrome.
Moya FR, Montes HF, Thomas VL, Mouzinho AM, Smith JF, Rosenfeld CR American journal of respiratory and critical care medicine 1994 Dec 150 6 Pt 1 1672-7 -
Angiotensin II metabolic clearance rate and pressor responses in nonpregnant and pregnant women.
Magness RR, Cox K, Rosenfeld CR, Gant NF American journal of obstetrics and gynecology 1994 Sep 171 3 668-79 -
Local and systemic estradiol-17 beta: effects on uterine and systemic vasodilation.
Magness RR, Rosenfeld CR The American journal of physiology 1989 Apr 256 4 Pt 1 E536-42 -
A prospective comparison of selective and universal electronic fetal monitoring in 34,995 pregnancies.
Leveno KJ, Cunningham FG, Nelson S, Roark M, Williams ML, Guzick D, Dowling S, Rosenfeld CR, Buckley A The New England journal of medicine 1986 Sep 315 10 615-9 -
Effect of angiotensin II on uterine and systemic vasculature in pregnant sheep.
Naden RP, Rosenfeld CR The Journal of clinical investigation 1981 Aug 68 2 468-74 -
The neonatal blood count in health and disease. I. Reference values for neutrophilic cells.
Manroe BL, Weinberg AG, Rosenfeld CR, Browne R The Journal of pediatrics 1979 Jul 95 1 89-98 -
The differential leukocyte count in the assessment and outcome of early-onset neonatal group B streptococcal disease.
Manroe BL, Rosenfeld CR, Weinberg AG, Browne R The Journal of pediatrics 1977 Oct 91 4 632-7 -
Distribution of cardiac output in ovine pregnancy.
Rosenfeld CR The American journal of physiology 1977 Mar 232 3 H231-5 -
Circulatory changes in the reproductive tissues of ewes during pregnancy.
Rosenfeld CR, Morriss FH, Makowski EL, Meschia G, Battaglia FC Gynecologic investigation 1974 5 5-6 252-68 -
Effect of estrogens on the uterine blood flow of oophorectomized ewes.
Killam AP, Rosenfeld CR, Battaglia FC, Makowski EL, Meschia G American journal of obstetrics and gynecology 1973 Apr 115 8 1045-52
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Fetal-placental crosstalk occurs through fetal cytokine synthesis and placental clearance.
Research
- Development of the renin-angiotensin system
- Cardiovascular role of estrogen in pregnancy
- Blood pressure regulation before and after birth
- Mechanisms modulating uteroplacental blood flow