David Hsieh, M.D., is an Assistant Professor in the Division of Hematology and Oncology at UT Southwestern Medical Center who specializes in the treatment of hepatocellular carcinoma, cholangiocarcinomas, and gall bladder cancers. Dr. Hsieh leads clinical trials to test new drugs or drug combinations in these cancers.

Dr. Hsieh earned his medical degree at the University of Arizona College of Medicine. He completed a residency in internal medicine at Mount Auburn Hospital in Cambridge, Massachusetts, and received advanced training in hematology and oncology through a fellowship at UT Southwestern. 

Certified by the American Board of Internal Medicine, Dr. Hsieh joined the UT Southwestern faculty in 2019.

Dr. Hsieh's other research interests include translational studies to understand mechanisms behind the variable effectiveness of cancer therapies between patients and the development of treatment biomarkers. He also researches processes, policies, and biases in scientific research and medicine.

His awards and honors include an ASH Research Training Award and an Early Career Investigator Award from the Cancer Prevention and Research Institute of Texas.

Honors & Awards
  • ASH Research Training Award for Fellows 2018
  • CPRIT Early Clinical Investigator Award 2020
  • Clinical trials in hepatocellular carcinoma and cholangiocarcinoma
  • Translational studies to identify markers of drug resistance
  • Discovering and advancing immunotherapies for liver cancers
  • Understanding mechanisms and bias in biomedical science