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Publications
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Genetic features and therapeutic relevance of emergent circulating tumor DNA alterations in refractory non-colorectal gastrointestinal cancers.
Hsiehchen D, Bucheit L, Yang D, Beg MS, Lim M, Lee SS, Kasi PM, Kaseb AO, Zhu H, Nature communications 2022 Dec 13 1 7477 -
Multinational teams and diseconomies of scale in collaborative research.
Hsiehchen D, Espinoza M, Hsieh A, Science advances 2015 Sep 1 8 e1500211 -
Clonal hematopoiesis and differential outcomes after immune checkpoint blockade.
Hsiehchen D, Sfreddo HJ, Zhao K, Han CY, Morris LGT, Cancer cell 2022 Oct 40 10 1071-1072 -
Nearing saturation of cancer driver gene discovery.
Hsiehchen D, Hsieh A, Journal of human genetics 2018 Sep 63 9 941-943 -
DNA Repair Gene Mutations as Predictors of Immune Checkpoint Inhibitor Response beyond Tumor Mutation Burden.
Hsiehchen D, Hsieh A, Samstein RM, Lu T, Beg MS, Gerber DE, Wang T, Morris LGT, Zhu H, Cell reports. Medicine 2020 Jun 1 3 -
Adherence to a Federal Hospital Price Transparency Rule and Associated Financial and Marketplace Factors.
Haque W, Ahmadzada M, Janumpally S, Haque E, Allahrakha H, Desai S, Hsiehchen D, JAMA 2022 06 327 21 2143-2145 -
Impact of tumor mutational burden on checkpoint inhibitor drug eligibility and outcomes across racial groups.
Hsiehchen D, Espinoza M, Valero C, Ahn C, Morris LGT, Journal for immunotherapy of cancer 2021 11 9 11
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Genetic features and therapeutic relevance of emergent circulating tumor DNA alterations in refractory non-colorectal gastrointestinal cancers.

David Hsieh, M.D.
- Internal Medicine - Hematology/Oncology
New Patient Appointment Accepting Virtual Visits or 214-645-8300
Biography
David Hsieh, M.D., is an Assistant Professor in the Division of Hematology and Oncology at UT Southwestern Medical Center who specializes in the treatment of hepatocellular carcinoma, cholangiocarcinomas, and gall bladder cancers. Dr. Hsieh leads clinical trials to test new drugs for liver cancers including hepatocellular carcinoma and cholangiocarcinomas.
Dr. Hsieh earned his medical degree at the University of Arizona College of Medicine. He completed a residency in internal medicine at Mount Auburn Hospital in Cambridge, Massachusetts, and received advanced training in hematology and oncology through a fellowship at UT Southwestern.
Certified by the American Board of Internal Medicine, Dr. Hsieh joined the UT Southwestern faculty in 2019.
Dr. Hsieh's other research interests include translational studies to understand mechanisms behind the variable effectiveness of cancer therapies between patients and the development of treatment biomarkers. He also researches processes, policies, and biases in scientific research and medicine.
His awards and honors include an Early Career Investigator Award from the Cancer Prevention and Research Institute of Texas.
Books & Publications
Research
- Clinical trials in hepatocellular carcinoma and cholangiocarcinoma
- Translational studies to identify markers of drug resistance
- Discovering and advancing immunotherapies for liver cancers
- Understanding mechanisms and bias in biomedical science
Results: 1 Locations
Cancer Care Outpatient Building
6202 Harry Hines Blvd.Dallas, Texas 75235 214-645-4673 Directions to Cancer Care Outpatient Building Parking Info for Cancer Care Outpatient Building
New Patient Appointment Accepting Virtual Visits or 214-645-8300 or 817-882-2400