- Internship - Mary Imogene Bassett Hospital (1976-1976), Internal Medicine
- Residency - University of South Alabama Medical Center (1977-1979), Internal Medicine
- Fellowship - Vanderbilt University Medical Center (1981-1983), Hematology Oncology
- Medical School - Medical College of Georgia at Augusta University (1972-1976)
David Johnson, M.D.
- R. Ellwood Jones, M.D. Distinguished Professorship in Clinical Education
- Internal Medicine - Hematology/Oncology
Biography
Dr. Johnson joined the UT Southwestern Medical Center faculty on July 1, 2010 as the Donald W. Seldin Distinguished Chair in Internal Medicine and Chairman of the Department of Internal Medicine. Prior to joining UT Southwestern he was a member of the faculty at the Vanderbilt University Medical School where he held the Cornelius A. Craig Chair of Medical & Surgical Oncology and served as the Director of the Division of Hematology and Medical Oncology and Deputy Director of the Vanderbilt-Ingram Cancer Center. He is a Past Chair of the American Board of Internal Medicine (ABIM) Board of Directors. He is also Past Chair of the ABIM Medical Oncology Subspecialty Board and a Past President of the American Society of Clinical Oncology (ASCO). During his term as ASCO President he helped advance the organization’s quality of care activity known as the Quality Oncology Practice Initiative (QOPI) and was instrumental in establishing ASCO’s Cancer Survivorship Program. Dr. Johnson has served on the Food and Drug Administration’s Oncology Drug Advisory Committee, as chairman of the Thoracic Committee of the Eastern Cooperative Oncology Group and on the Board of Directors of the National Comprehensive Cancer Network, the International Association for the Study of Lung Cancer and the LiveSTRONG Foundation. Dr. Johnson’s research interests involve understanding the biology of lung cancer and improving the treatment of this and other solid tumors. He played a role in the development of the new targeted drugs bevacizumab (Avastin) and erlotinib (Tarceva) both of which are now FDA-approved for the treatment of lung cancer. Dr. Johnson earned his medical degree from the Medical College of Georgia and received medical oncology training at Vanderbilt University.
Education & Training
Professional Associations & Affiliations
- American Association for Cancer Research
- American College of Physicians, Master
- American Society of Clinical Oncology, Fellow
- Association of American Physicians
- International Association for the Study of Lung Cancer
Honors & Awards
- ASCO Distinguished Achievement Award 2016
- College of Arts & Sciences Hall of Fame, University of Kentucky 2015
- Master, American College of Physicians 2015
- Chairman, American Board of Internal Medicine Board of Directors 2013-2015
- Established Investigator Award, CPRIT 2010
- Association of American Physicians 2009
- Clinical Research Award, Association of Community Cancer Centers 2007
- Distinguished Southern Oncologist Award, Southern Association of Oncology 2006
- President, American Society of Clinical Oncology 2004-2005
- Alpha Omega Alpha 1975
Books & Publications
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Books
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Lung Cancer, Principles & Practice.
Harvey I. Pass, David P. Carbone, David H. Johnson, John D. Minna, G. Scagliotti, Andrew T. Turrisi, eds. (2010), Philadelphia, Lippincott Williams & Wilkins -
Textbook of Uncommon Cancer - 4th ed
D. Raghavan, C.D. Blanke, D.H. Johnson, P.L. Moots, G.H. Reaman, P.G. Rose, M.K. Sekeres; eds (2012), Hoboken, NJ, Wiley-Blackwell
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Lung Cancer, Principles & Practice.
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Publications
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Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer.
Lovly CM, McDonald NT, Chen H, Ortiz-Cuaran S, Heukamp LC, Yan Y, Florin A, Ozretic L, Lim D, Wang L, Chen Z, Chen X, Lu P, Paik PK, Shen R, Jin H, Buettner R, Ansén S, Perner S, Brockmann M, Bos M, Wolf J, Gardizi M, Wright GM, Solomon B, Russell PA, Rogers TM, Suehara Y, Red-Brewer M, Tieu R, de Stanchina E, Wang Q, Zhao Z, Johnson DH, Horn L, Wong KK, Thomas RK, Ladanyi M, Pao W Nature medicine 2014 Aug -
Preoperative chemotherapy for non-small-cell lung cancer: a systematic review and meta-analysis of individual participant data.
Lancet 2014 May 383 9928 1561-71 -
Clinical course of advanced non-small cell lung cancer patients experiencing hypertension during treatment with bevacizumab in combination with carboplatin and paclitaxel on ECOG 4599.
Dahlberg SE, Sandler AB, Brahmer JR, Schiller JH, Johnson DH J Clin Oncol 2010 28 949-54 -
Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data.
NSCLC Meta-analyses Collaborative Group, Arriagada R, Auperin A, Burdett S, Higgins JP, Johnson DH, Le Chevalier T, Le Pechoux C, Parmar MK, Pignon JP, Souhami RL, Stephens RJ, Stewart LA, Tierney JF, Tribodet H, van Meerbeeck J. The Lancet 2010 375 1267-77 -
Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators.
Wang SE, Yu Y, Criswell TL, Debusk LM, Lin PC, Zent R, Johnson DH, Ren X, Arteaga CL. Oncogene 2010 29 3335-48 -
Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial
Albain KS, Swann RS, Rusch VW, Turrisi AT, Shepherd FA, Smith C, Chen Y, Livingston RB, Feins RH, Gandara DR, Fry WA, Darling G, Johnson DH, Green MR, Miller RC, Ley J, Sause WT, Cox JD The Lancet 2009 374 379-86 -
Molecular characteristics of bronchioloalveolar carcinoma and adenocarcinoma, bronchioloalveolar carcinoma subtype, predict response to erlotinib
Miller VA, Riely GJ, Zakowski MF, Li AR, Patel JD, Heelan RT, Kris MG, Sandler AB, Carbone DP, Tsao A, Herbst RS, Heller G, Ladanyi M, Pao W, Johnson DH J Clin Oncol 2008 26 1472-78 -
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
Sandler A, Gray R, Perry MC, Brahmer J, Schiller JH, Dowlati A, Lilenbaum R, Johnson DH N Engl J Med 2006 355 2542-50 -
Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer
Winton T, Livingston R, Johnson DH, Rigas J, Johnston M, Butts C, Cormier Y, Goss G, Inculet R, Vallieres E, Fry W, Bethune D, Ayoub J, Ding K, Seymour L, Graham B, Tsao M-S, Gandara D, Kesler K, Demmy T, Shepherd F N Engl J Med 2005 352 2589-97 -
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
Schiller JH, Harrington D, Belani CP, Langer C, Sandler A, Krook J, Zhu J, Johnson DH N Engl J Med 2002 346 92-8 -
A randomized trial of postoperative adjuvant therapy in patients with completely resected stage II or IIIA non-small-cell lung cancer. Eastern Cooperative Oncology Group
Keller SM, Adak S, Wagner H, Herskovic A, Komaki R, Brooks BJ, Perry MC, Livingston RB, Johnson DH N Engl J Med 2000 343 1217-22 -
Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide
Turrisi AT, Kim K, Blum R, Sause WT, Livingston RB, Komaki R, Wagner H, Aisner S, Johnson DH N Engl J Med 1999 340 265-71
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Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer.
Research
- Developmental therapeutics
- Lung cancer therapeutics