- American Epilepsy Society (2008)
- American Academy of Neurology (2011)
Deepa Sirsi, M.D.
- Pediatric Neurology
- General Neurology
- Epilepsy & Seizures
Biography
Deepa Sirsi, M.D., is a Professor in the Departments of Pediatrics and Neurology at UT Southwestern Medical Center. Specializing in pediatric neurology and epilepsy, she serves as Program Director for the Pediatric Epilepsy Fellowship program.
Dr. Sirsi earned her medical degree at Bangalore Medical College and Research Institute in Bangalore, India. She completed a residency in pediatrics at the Newark Beth Israel Medical Center and received advanced training in pediatric neurology and neurophysiology through separate fellowships at NewYork-Presbyterian/Weill Cornell Medical Center and Albert Einstein College of Medicine/Montefiore Medical Center, respectively.
Certified by the American Board of Psychiatry and Neurology in child neurology, clinical neurophysiology, and epilepsy, Dr. Sirsi joined the UT Southwestern faculty in 2008.
Dr. Sirsi’s research focus is in clinical trials for intractable epilepsy and Lennox-Gastaut syndrome. Her clinical interests include pediatric genetic epilepsy syndromes, dietary treatments for epilepsy, and surgery for medically intractable epilepsy.
She is a member of the American Academy of Neurology, the American Epilepsy Society, and the Child Neurology Society.
To schedule an appointment with Dr. Sirsi at Children's Health, please call 844-4CHILDRENS or request an appointment online.
Education & Training
- Medical School - Bangalore Medical College, India (1994-1999)
- Fellowship - Albert Einstein College of Medicine/Montefiore Medical Center (2007-2008), Neurophysiology
- Residency - Newark Beth Israel Medical Center (2002-2004), Pediatrics
- Residency - New York Presbyterian Hospital/Cornell Campus (2004-2007), Pediatric Neurology
Professional Associations & Affiliations
Honors & Awards
- Best Pediatric Specialists 2017, D Magazine
- Best Doctors in Dallas 2016, D Magazine
- Intern of the Year Award 2003, Pediatrics, Newark Beth Israel Medical Center
- Top Scholar Award 2007, Epilepsy Foundation
Books & Publications
-
Books
-
Epilepsy Board Review. 1st ed.
Modur PN, Gupta PK, Sirsi D. (2016), New York: Demos Medical Publishing.
-
Epilepsy Board Review. 1st ed.
-
Publications
-
Amygdala enlargement in pediatric epilepsy: A clinically meaningful finding?
Hakim M, Joshi C, Veltkamp D, Sirsi D, Nguyen L, Bhatia S, Armstrong D, Prabhu N, Talai A Epilepsy Research 2026 Jun 224 -
Early Electroencephalogram to Predict Severity of Injury in Infants With Abusive Traumatic Brain Injury
Varughese NA, Hasan A, Cohen N, Smith D, Clarke RL, Grapsy J, Said R, Miles D, Raman L, Sirsi D Journal of child neurology 2026 May 41 704-714 -
The association between early arterial oxygen and carbon dioxide with neurologic outcomes after pediatric ECPR in children with cardiac disease
Yu P, Foster S, Zeida Haar L, Li X, Bhaskar P, Morriss M, Singh S, Burr T, Sirsi D, Raman L, Reeder R, Lasa JJ Resuscitation 2026 May 222 -
Clinical trajectories and medication response in TBC1D24-related epilepsies
Mondragon E, Magielski JH, Bane B, Nolan JL, Ruggiero SM, Armstrong D, Arnold S, Sirsi D, Helbig I, McKee JL Epilepsia 2026 Mar 67 1386-1397 -
Delta Power in SLC6A1-Related Neurodevelopmental Disorder: Operationalizing Quantitative EEG Metrics for Biomarker Development
Dahshi H, Varnet M, Goodspeed K, Tiller J, Armstrong D, Sirsi D Neurology International 2026 Mar 18 -
Treatment Practices for Infantile Epileptic Spasms Syndrome: Consensus and Variation in Major Pediatric Epilepsy Centers
Briscoe C, Katyayan A, Harini C, Hussain SA, Bhalla S, Singh A, Donatelli S, Sandoval Karamian AG, Samanta D, Sirsi D, Catenaccio E, Planchart Ferretto MA, Thio LL, Hunter SE, Spriha P, Rao CK, Bhatia S, Erdemir G, Shrey DW, Numis AL Pediatric Neurology 2026 Jan 174 46-53 -
Pediatric RNS Lead Migration: Wandering Eyes or Electrode?
Joshi C, Veltkamp D, Dodez C, Warren AE, Sirsi D, Talai A, Said R, Price A Annals of Neurology 2025 Aug 98 354-356 -
Thalamic stereo-electroencephalography exploration in pediatric drug-resistant epilepsy: implantation technique and complications
Price AV, Sirsi D, Joshi C Journal of Neurosurgery: Pediatrics 2025 Apr 35 361-368 -
A Multicenter Training and Interrater Reliability Study of the BASED Score for Infantile Epileptic Spasms Syndrome
Mytinger JR, Albert DV, Aylward SC, Beatty CW, Bhalla S, Bhatia S, Brock GN, Ciliberto MA, Choudhari PR, Clark DJ, Cohen JM, Czech TM, Fredwall MM, Gonzalez-Giraldo E, Harini C, Hunter SE, Sandoval Karamian AG, Katyayan A, Kistler I, Kulkarni N, Liu VB, McCabe C, Murray T, Neville K, Patel SH, Pavuluri S, Phillips DJ, Samanta D, Sirsi D, Spelbrink EM, Stafstrom CE, Steenari M, Takacs DS, Terrill T, Tran L, Vidaurre J, Shrey DW Journal of Clinical Neurophysiology 2025 Mar 42 230-234 -
The association between early hypotension and neurologic outcome after pediatric cardiac ECPR in children with cardiac disease
Yu P, Foster S, Li X, Bhaskar P, Morriss MC, Singh S, Burr T, Sirsi D, Raman L, Lasa JJ Resuscitation Plus 2024 Dec 20 -
Barriers to Medication Adherence in People Living With Epilepsy
Author Collaboration TE, Donahue MA, Akram H, Brooks JD, Modi AC, Veach J, Kukla A, Benard SW, Herman ST, Farrell K, Ficker DM, Zafar SF, Trescher WH, Sirsi D, Phillips DJ, Pellinen J, Buchhalter J, Moura L, Fureman BE, Yu A, Meier A, Anderson A, Egbert A, Gaines A, John A, Riisen A, Kheder A, Chima A, Paul A, Pounders A, Rubin A, Modi A, Dworetzky B, Shirley B, Johnsrud B, Grzeskowiak C, Howell C, Brocker C, Winters C, Nwankwo C, Heck C, Godale C, Byrnes C, Hall C, Ficker D, Bailey DM, Holder D, Rectenwald D, Sirsi D, De Los Santos D, Kulasa D Neurology: Clinical Practice 2024 Nov 15 -
Back to Basics: Care of the Stereotactic EEG Implanted Patient
Alick-Lindstrom S, Venkatesh P, Perven G, Wabulya A, Yang QZ, Sirsi D, Podkorytova I Journal of Clinical Neurophysiology 2024 Jul 41 415-422 -
Neuromonitoring of Pediatric and Adult Extracorporeal Membrane Oxygenation Patients: The Importance of Continuous Bedside Tools in Driving Neuroprotective Clinical Care
Tabet M, Custer C, Khan IR, Sanford E, Sharma J, Choe R, Singh S, Sirsi D, Olson DM, Morriss MC, Raman L, Busch DR ASAIO Journal 2024 Mar 70 167-176 -
Neuroinflammation and Autoregulation During Pediatric Extracorporeal Life Support
Tabet M, McAtee AM, Custer C, Sanford E, Weldon-Carroll RC, Sharma J, Abioye A, Sirsi D, Singh S, Morriss MC, Turchan-Cholewo JT, Olson DW, Raman L, Stowe AM, Busch DR 2024 -
Neuroinflammation and Autoregulation During Pediatric Extracorporeal Life Support
Tabet M, McAtee AM, Custer C, Sanford E, Weldon-Carroll RC, Sharma J, Abioye A, Sirsi D, Singh S, Morriss MC, Turchan-Cholewo JT, Olson DW, Raman L, Stowe AM, Busch DR 2024 -
Combination of triheptanoin with the ketogenic diet in Glucose transporter type 1 deficiency (G1D)
Avila A, Málaga I, Sirsi D, Kayani S, Primeaux S, Kathote GA, Jakkamsetti V, Kallem RR, Putnam WC, Park JY, Shinnar S, Pascual JM Scientific reports 2023 Dec 13 -
Electroencephalographic (EEG) Biomarkers in Genetic Neurodevelopmental Disorders
Goodspeed K, Armstrong D, Dolce A, Evans P, Said R, Tsai P, Sirsi D Journal of child neurology 2023 May 38 466-477 -
EEG and clinical characteristics of neonatal parechovirus encephalitis
Sirsi D, Lowden A, Dolce A, Machie M, Thomas J, Joshi C Epilepsy Research 2023 May 192 -
Metabolic modulation of synaptic failure and thalamocortical hypersynchronization with preserved consciousness in Glut1 deficiency
Rajasekaran K, Ma Q, Good LB, Kathote G, Jakkamsetti V, Liu P, Avila A, Primeaux S, Alva JE, Markussen KH, Marin-Valencia I, Sirsi D, Hacker PM, Gentry MS, Su J, Lu H, Pascual JM Science translational medicine 2022 Oct 14 -
Epilepsy Course and Developmental Trajectories in STXBP1 -DEE
Balagura G, Xian J, Riva A, Marchese F, Zeev BB, Rios L, Sirsi D, Accorsi P, Amadori E, Astrea G, Baldassari S, Beccaria F, Boni A, Budetta M, Cantalupo G, Capovilla G, Cesaroni E, Chiesa V, Coppola A, Dilena R, Faggioli R, Ferrari A, Fiorini E, Madia F, Gennaro E, Giacomini T, Giordano L, Iacomino M, Lattanzi S, Marini C, Mancardi MM, Mastrangelo M, Messana T, Minetti C, Nobili L, Papa A, Parmeggiani A, Pisano T, Russo A, Salpietro V, Savasta S, Scala M, Accogli A, Scelsa B, Scudieri P, Spalice A, Specchio N, Trivisano M, Tzadok M, Valeriani M, Vari MS, Verrotti A, Vigevano F, Vignoli A, Toonen R, Zara F, Helbig I, Striano P Neurology: Genetics 2022 Jun 8 -
Epilepsy and electroencephalography in Pitt-Hopkins syndrome
Bone M, Goodspeed K, Sirsi D Journal of Translational Genetics and Genomics 2022 6 169-178 -
Paroxysmal Tonic Downgaze: A Pseudo Sunsetting Sign
Sirsi D, Armstrong D Journal of Pediatrics 2021 Mar 230 263-264 -
Eeg is a predictor of neuroimaging abnormalities in pediatric extracorporeal membrane oxygenation
Fox J, Jenks CL, Farhat A, Li X, Liu Y, James E, Karasick S, Morriss MC, Sirsi D, Raman L Journal of Clinical Medicine 2020 Aug 9 1-11 -
Spatially clustering de novo variants in CYFIP2, encoding the cytoplasmic FMRP interacting protein 2, cause intellectual disability and seizures
Author Collaboration DD, Zweier M, Begemann A, McWalter K, Cho MT, Abela L, Banka S, Behring B, Berger A, Brown CW, Carneiro M, Chen J, Cooper GM, Finnila CR, Guillen Sacoto MJ, Henderson A, Hüffmeier U, Joset P, Kerr B, Lesca G, Leszinski GS, McDermott JH, Meltzer MR, Monaghan KG, Mostafavi R, Õunap K, Plecko B, Powis Z, Purcarin G, Reimand T, Riedhammer KM, Schreiber JM, Sirsi D, Wierenga KJ, Wojcik MH, Papuc SM, Steindl K, Sticht H, Rauch A European Journal of Human Genetics 2019 May 27 747-759 -
De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females
Author Collaboration DS, Palmer EE, Stuhlmann T, Weinert S, Haan E, van Esch H, Holvoet M, Boyle J, Leffler M, Raynaud M, Moraine C, van Bokhoven H, Kleefstra T, Kahrizi K, Najmabadi H, Ropers HH, Delgado MR, Sirsi D, Golla S, Sommer A, Pietryga MP, Chung WK, Wynn J, Rohena L, Bernardo E, Hamlin D, Faux BM, Grange DK, Manwaring L, Tolmie J, Joss S, Cobben JM, Duijkers FA, Goehringer JM, Challman TD, Hennig F, Fischer U, Grimme A, Suckow V, Musante L, Nicholl J, Shaw M, Lodh SP, Niu Z, Rosenfeld JA, Stankiewicz P, Jentsch TJ, Gecz J, Field M, Kalscheuer VM Molecular psychiatry 2018 Feb 23 222-230 -
Fosphenytoin-induced dyskinesias in an infant with Sturge-Weber syndrome
Thodeson DM, Reiber DC, Dolce AM, Sirsi D Neurology 2016 Apr 86 1561-1562 -
Type II Cortical Dysplasia in Dominant Frontal Lobe Presenting as Gelastic Epilepsy
Dubey D, Thodeson D, Dowling M, Sirsi D, Arnold S, Said R Pediatric Neurology 2015 Jul 53 97-98 -
Is intranasal midazolam better than rectal diazepam for home management of acute seizures?
Sirsi D Archives of neurology 2011 Jan 68 120-121 -
Successful management of refractory neonatal seizures with midazolam
Sirsi D, Nangia S, LaMothe J, Kosofsky BE, Solomon GE Journal of child neurology 2008 Jun 23 706-709 -
Apneic Seizures: A Sign of Temporal Lobe Hemorrhage in Full-Term Neonates
Sirsi D, Nadiminti L, Packard MA, Engel M, Solomon GE Pediatric Neurology 2007 Nov 37 366-370 -
The safety of levetiracetam
Sirsi D, Safdieh JE Expert Opinion on Drug Safety 2007 May 6 241-250
-
Amygdala enlargement in pediatric epilepsy: A clinically meaningful finding?
Research
- Treatment of refractory epilepsy
Clinical Focus
- General Neurology
- Epilepsy & Seizures
Children's Medical Center of Dallas
1935 Medical District DriveDallas, Texas 75235 214-730-5437 Directions to Children's Medical Center of Dallas at Children's Medical Center of Dallas, Dallas