Dwight Towler, M.D., Ph.D.

Dwight Towler, M.D., Ph.D.

Vice Chair, Research - Internal Medicine

  • Louis V. Avioli Professorship in Mineral Metabolism Research
  • J.D. and Maggie E. Wilson Distinguished Chair in Biomedical Research
  • Internal Medicine - Endocrinology

Biography

Dwight Arnold Towler, M.D., Ph.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He serves as the department’s Vice Chair for Research. A specialist in bone and mineral metabolism disorders – including osteoporosis and the vascular calcification that hardens arteries with aging, diabetes, and chronic kidney disease – he holds both the J.D. and Maggie E. Wilson Distinguished Chair in Biomedical Research and the Louis V. Avioli Professorship in Mineral Metabolism Research.

Dr. Towler earned his medical degree and doctorate in biochemistry at Washington University in St. Louis (WUSTL). He completed his residency in internal medicine and fellowship in metabolism at Barnes-Jewish Hospital.

Certified by the American Board of Internal Medicine, Dr. Towler joined the UT Southwestern faculty in 2015. He previously served at WUSTL as the Lang Professor of Medicine in the Division of Endocrinology, Metabolism, and Lipid Research and the Chief of the Division of Bone and Mineral Diseases.

In addition to his career in academic medicine, Dr. Towler spent four years in the pharmaceutical industry. He is co-inventor of novel, patented selective androgen receptor modulators (SARMs) that have potential clinical applications in the treatment of musculoskeletal frailty.

Dr. Towler’s Ph.D. research focused on pioneering studies of protein fatty acid acylation. His current research focuses on the endocrine physiology of bone and vascular disease.

He has authored numerous articles, book chapters, and invited lectures, and he serves as a reviewer for multiple journals and as a guest editor and editorial board member for Arteriosclerosis Thrombosis and Vascular Biology. His research has been recognized by the Charles E. Culpeper Foundation, the American Society for Bone and Mineral Research, the American Society for Clinical Investigation, and the Association of American Physicians.

Dr. Towler is a member of the American Heart Association, the American Society for Bone and Mineral Research, the Endocrine Society, the American Society for Clinical Investigation, and the Association of American Physicians.

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Education & Training
  • Medical School - Washington University School of Medicine (1983-1989)
  • Residency - Washington University/Barnes Hospital (1989-1991), Internal Medicine
  • Fellowship - Washington University/Barnes Hospital (1991-1992), Metabolism
Professional Associations & Affiliations
  • The Endocrine Society (1995), Member
  • American Society for Bone and Mineral Research (1993), Member
  • American Society for Clinical Investigation (2004), Member
  • American Heart Association (2003), Member
Honors & Awards
  • Charles E. Culpeper Medical Science Scholar 1996-1999, Career Development Award
  • Fuller Albright Award, American Society for Bone and Mineral Research 2000, Young Investigator Award
  • The 12th Annual John G. Haddad, Jr., MD Memorial Lecture, University of Pennsylvania 2009, Honorary Visiting Lectureship
  • Bayard D. Catherwood Lecturer and Visiting Professor, Emory University 2006, Honorary Visiting Lectureship
  • Elected, American Society for Clinical Investigation 2004, Physician-Scientist Honorary Society
  • J.D. and Maggie E. Wilson Distinguished Chair in Biomedical Sciences, UT Southwestern Medical Center, Internal Medicine - Division of Endocrinology 2015, Endowed Chair
  • University of Texas System Faculty STARS Program Award, UT Southwestern Medical Center 2015, Translational Research Award
  • Guest Editor, Circulation Research Series of Pathobiology of Calcific Vasculopathy and Valvulopathy 2011, Invited Guest Editor
  • Ira M. Lang Endowed Chair in Internal Medicine, Barnes-Jewish Hospital at Washington University Medical Center 2004-2012, Endowed Chair
Books & Publications
Research
  • Wnt signaling
  • Transcriptional regulation
  • Protein Arginine Methylation / Demethylation
  • Cardiovascular calcification
  • Bone and Mineral Disease