E. Sherwood Brown, M.D., Ph.D.

Distinguished Teaching Professor

  • Lou and Ellen McGinley Distinguished Chair in Psychiatric Research
  • Aradine S. Ard Chair in Brain Science
  • Psychiatry


E. Sherwood Brown, M.D., Ph.D., M.B.A., is a Professor of Psychiatry with Tenure, Vice Chair for Clinical Research, Chief of the Division of Clinical Neuroscience, and Director of the Psychoneuroendocrine Research Program at UT Southwestern Medical Center. Dr. Brown received his B.A. and Ph.D. degrees in chemistry from Texas Christian University. He earned his M.D. degree at the University of Texas Medical School at Houston, and completed a psychiatry residency on the research track at UT Southwestern Medical Center, followed by a research fellowship. He also received an M.B.A. (Healthcare Leadership Concentration) from UT Dallas.

Dr. Brown is board certified in psychiatry and consultation-liaison psychiatry.

He serves on the editorial boards of several journals, including Journal of Affective Disorders, and is Editor-in-Chief of the Journal of Dual Diagnosis. He also serves as Treasurer and as a member of the board of directors and executive committee of the Academy of Consultation Liaison Psychiatry.

Dr. Brown’s research focuses on comorbidities of mood disorders including medical illness and substance abuse. He has received numerous grants from both the National Institutes of Health and private foundations, including grants from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA) examining the treatment of patients with bipolar disorder and substance use disorders, grants from the National Heart, Lung, and Blood Institute (NHLBI) examining the treatment of depressed asthma patients, grants from the National Institute of Mental Health (NIMH) exploring interventions to protect the brain from the effects of corticosteroid excess, and grants from the National Center for Complementary and Integrative Health (NCCIH) examining a novel supplements.

Dr. Brown has published well over 200 research papers, books, chapters, reviews and editorials. 

Education & Training
  • Fellowship - UT Southwestern Medical Center (1997-1998), Research
  • Residency - UT Southwestern Medical Center (1994-1997), Psychiatry
  • Internship - UT Southwestern Medical Center (1993-1994), Psychiatry
  • Medical School - UT Health Science Center McGovern Medical School (1989-1993)
Professional Associations & Affiliations
  • Society of Biological Psychiatry
  • Research Society on Alcoholism
  • American Psychiatric Association
  • American College of Neuropsychopharmacology
  • Texas Medical Association (1993)
  • Academy of Consultation-Liaison Psychiatry (2005)
Honors & Awards
  • Lilly Fellowship Travel Award 1998, to Society of Biological Psychiatry Annual Convention
  • New Investigator Award 1997, from New Clinical Drug Evaluation Unit (NCDEU)
  • Bristol-Myers Squibb Travel Fellowship 1999, to American College of Neuropsychopharmacology (ACNP) Annual Meeting
  • Gerald L. Klerman Award 2002, for clinical research from National Alliance for Research in Schizophrenia and Depression (NARSAD)
Books & Publications
  • Treatment of patients with bipolar disorder and substance abuse
  • Treatment of bipolar depression
  • Effects of corticosteroids on the hippocampus
  • Depression in asthma patients