- Fellowship - UT Southwestern Medical Center (1997-1998), Research
- Residency - UT Southwestern Medical Center (1994-1997), Psychiatry
- Internship - UT Southwestern Medical Center (1993-1994), Psychiatry
- Medical School - UT Health Science Center McGovern Medical School (1989-1993)
E Sherwood Brown, M.D., Ph.D.
- Aradine S. Ard Chair in Brain Science
E. Sherwood Brown, M.D., Ph.D., is Professor of Psychiatry with Tenure, Vice Chair for Clinical Research, Chief of the Division of Clinical Neuroscience, and Director of the Psychoneuroendocrine Research Program at The University of Texas Southwestern Medical Center. He received B.A. and Ph.D. degrees in Chemistry from Texas Christian University. He received an M.D. degree from the University of Texas Medical School at Houston, and completed a psychiatry residency, on the research track, at UT Southwestern Medical Center followed by a research fellowship. He is board certified in psychiatry and psychosomatic medicine.
He serves on several journal editorial boards including Biological Psychiatry and Journal of Affective Disorders, and is co-Editor-in-Chief of the Journal of Dual Diagnosis. Dr. Brown’s research focuses on comorbidities of mood disorders including medical illness and substance abuse. He has had numerous grants from NIH and private foundations, including grants from NIAAA and NIDA examining the treatment of patients with bipolar disorder and substance dependence, a grant from NHLBI examining the treatment of depressed asthma patients a grant from NIMH exploring interventions to protect the brain from the effects of corticosteroid excess, and a grant from NCCIH examining a novel botanical agent. He has published over 140 research papers, books, chapters, reviews and editorials.
- Society of Biological Psychiatry
- Research Society on Alcoholism
- American Psychiatric Association
- American College of Neuropsychopharmacology
- Texas Medical Association (1993)
- Academy of Consultation-Liaison Psychiatry (2005)
- Lilly Fellowship Travel Award 1998, to Society of Biological Psychiatry Annual Convention
- New Investigator Award 1997, from New Clinical Drug Evaluation Unit (NCDEU)
- Bristol-Myers Squibb Travel Fellowship 1999, to American College of Neuropsychopharmacology (ACNP) Annual Meeting
- Gerald L. Klerman Award 2002, for clinical research from National Alliance for Research in Schizophrenia and Depression (NARSAD)
A randomized, placebo-controlled trial of citicoline add-on therapy in outpatients with bipolar disorder and cocaine dependence.
Brown ES, Gorman AR, Hynan LS Journal of clinical psychopharmacology 2007 Oct 27 5 498-502
Hippocampal Volume in Healthy Controls Given 3-Day Stress Doses of Hydrocortisone.
Brown ES, Jeon-Slaughter H, Lu H, Jamadar R, Issac S, Shad M, Denniston D, Tamminga C, Nakamura A, Thomas BP Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014 Nov
Effects of glucocorticoids on mood, memory, and the hippocampus. Treatment and preventive therapy.
Brown ES Annals of the New York Academy of Sciences 2009 Oct 1179 41-55
An epidemiological approach to "steroid psychosis".
Brown ES The American journal of psychiatry 2012 May 169 5 447-9
A Randomized, Double-Blind, Placebo-Controlled Trial of Pregnenolone for Bipolar Depression.
Brown ES, Park J, Marx CE, Hynan LS, Gardner C, Davila D, Nakamura A, Sunderajan P, Lo A, Holmes T Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014 Jun
A randomized, placebo-controlled proof-of-concept, crossover trial of phenytoin for hydrocortisone-induced declarative memory changes.
Brown ES, Lu H, Denniston D, Uh J, Thomas BP, Carmody TJ, Auchus RJ, Diaz-Arrastia R, Tamminga C Journal of affective disorders 2013 Feb
Relationship between asthma and cognition: the Cooper Center Longitudinal Study.
Caldera-Alvarado G, Khan DA, Defina LF, Pieper A, Brown ES Allergy 2013 Feb
Depression, anxiety, and COPD: the unexamined role of nicotine dependence.
Goodwin RD, Lavoie KL, Lemeshow AR, Jenkins E, Brown ES, Fedoronko DA Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012 Feb 14 2 176-83
A randomized, double-blind, placebo-controlled pilot study of naltrexone in outpatients with bipolar disorder and alcohol dependence.
Brown ES, Carmody TJ, Schmitz JM, Caetano R, Adinoff B, Swann AC, John Rush A Alcoholism, clinical and experimental research 2009 Nov 33 11 1863-9
Hippocampal volume, spectroscopy, cognition, and mood in patients receiving corticosteroid therapy.
Brown ES, J Woolston D, Frol A, Bobadilla L, Khan DA, Hanczyc M, Rush AJ, Fleckenstein J, Babcock E, Cullum CM Biological psychiatry 2004 Mar 55 5 538-45
Attenuation of amygdala atrophy with lamotrigine in patients receiving corticosteroid therapy.
Desai S, Khanani S, Shad MU, Brown ES Journal of clinical psychopharmacology 2009 Jun 29 3 284-7
Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects.
Judd LL, Schettler PJ, Brown ES, Wolkowitz OM, Sternberg EM, Bender BG, Bulloch K, Cidlowski JA, Ronald de Kloet E, Fardet L, Joëls M, Leung DY, McEwen BS, Roozendaal B, Van Rossum EF, Ahn J, Brown DW, Plitt A, Singh G The American journal of psychiatry 2014 Oct 171 10 1045-51
Asthma and depression: the Cooper Center Longitudinal Study.
Trojan TD, Khan DA, Defina LF, Akpotaire O, Goodwin RD, Brown ES Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2014 Mar
The effect of cognitive functioning on treatment attendance and adherence in comorbid bipolar disorder and cocaine dependence.
Fagan CS, Carmody TJ, McClintock SM, Suris A, Nakamura A, Jeon-Slaughter H, Lo A, Brown ES Journal of substance abuse treatment 2014 Jul
Citicoline in addictive disorders: a review of the literature.
Wignall ND, Brown ES The American journal of drug and alcohol abuse 2014 Jul 40 4 262-8
The relationship between asthma and self-reported anxiety in a predominantly healthy adult population.
Gada E, Khan DA, Defina LF, Brown ES Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2013 Sep
Association of Depressive Symptoms with Hippocampal Volume in 1936 Adults.
Brown ES, Hughes CW, McColl R, Peshock R, King KS, Rush AJ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013 Oct
Relationship between serum homocysteine levels and depressive symptoms: the Cooper Center Longitudinal Study.
Gu P, DeFina LF, Leonard D, John S, Weiner MF, Brown ES The Journal of clinical psychiatry 2012 May 73 5 691-5
A randomized, double-blind, placebo-controlled trial of citicoline for bipolar and unipolar depression and methamphetamine dependence.
Brown ES, Gabrielson B Journal of affective disorders 2012 Dec 143 1-3 257-60
T2 measurement of J-coupled metabolites in the human brain at 3T.
Ganji SK, Banerjee A, Patel AM, Zhao YD, Dimitrov IE, Browning JD, Brown ES, Maher EA, Choi C NMR in biomedicine 2012 Apr 25 4 523-9
Association between low serum 25-hydroxyvitamin D and depression in a large sample of healthy adults: the Cooper Center longitudinal study.
Hoang MT, Defina LF, Willis BL, Leonard DS, Weiner MF, Brown ES Mayo Clinic proceedings. Mayo Clinic 2011 Nov 86 11 1050-5
Effects of lamotrigine on hippocampal activation in corticosteroid-treated patients.
Brown ES, Zaidel L, Allen G, McColl R, Vazquez M, Ringe WK Journal of affective disorders 2010 Nov 126 3 415-9
A double-blind, placebo-controlled study with quetiapine as adjunct therapy with lithium or divalproex in bipolar I patients with coexisting alcohol dependence.
Stedman M, Pettinati HM, Brown ES, Kotz M, Calabrese JR, Raines S Alcoholism, clinical and experimental research 2010 Oct 34 10 1822-31
Pregnenolone for cognition and mood in dual diagnosis patients.
Osuji IJ, Vera-Bolaños E, Carmody TJ, Brown ES Psychiatry research 2010 Jul 178 2 309-12
Association of depression with medical illness: does cortisol play a role?
Brown ES, Varghese FP, McEwen BS Biological psychiatry 2004 Jan 55 1 1-9
Factitious angioedema: a mimic of refractory "angioedema".
Feldman MF, Khan DA, Brown ES, Bernstein JA The journal of allergy and clinical immunology. In practice 2014 Nov-Dec 2 6 795-7
A comparison of clinician-rated neuropsychological and self-rated cognitive assessments in patients with asthma and rheumatologic disorders.
Frol AB, Vasquez A, Getahun Y, Pacheco M, Khan DA, Brown ES Allergy and asthma proceedings : the official journal of regional and state allergy societies 2013 Mar 34 2 170-5
A randomized, double-blind, placebo-controlled add-on trial of quetiapine in outpatients with bipolar disorder and alcohol use disorders.
Brown ES, Garza M, Carmody TJ The Journal of clinical psychiatry 2008 May 69 5 701-5
A randomized, double-blind, placebo-controlled, trial of lamotrigine therapy in bipolar disorder, depressed or mixed phase and cocaine dependence.
Brown ES, Sunderajan P, Hu LT, Sowell SM, Carmody TJ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012 Oct 37 11 2347-54
Escitalopram for severe asthma and major depressive disorder: a randomized, double-blind, placebo-controlled proof-of-concept study.
Brown ES, Howard C, Khan DA, Carmody TJ Psychosomatics 2012 Jan-Feb 53 1 75-80
A randomized trial of citalopram versus placebo in outpatients with asthma and major depressive disorder: a proof of concept study.
Brown ES, Vigil L, Khan DA, Liggin JD, Carmody TJ, Rush AJ Biological psychiatry 2005 Dec 58 11 865-70
- A randomized, placebo-controlled trial of citicoline add-on therapy in outpatients with bipolar disorder and cocaine dependence.
- Treatment of patients with bipolar disorder and substance abuse
- Treatment of bipolar depression
- Effects of corticosteroids on the hippocampus
- Depression in asthma patients