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Peter O'Donnell Jr. Brain Institute

The Peter O’Donnell Jr. Brain Institute brings together transformative research and patient-centered care to improve the lives of patients today and those of generations to come.

Improving Patient Care

The Peter O’Donnell Jr. Brain Institute aims to advance our understanding of brain diseases and injury. Our ultimate goal: improve treatment options and discover ways to prevent such illnesses. 

Unfortunately, phrases like “there is no cure” are heard all too often by those who have brain diseases and disorders ranging from Alzheimer’s and aggressive brain tumors to traumatic brain injuries. At the O’Donnell Brain Institute, we provide advanced diagnostic capabilities and treatment options for the full spectrum of brain, spine, muscle, nerve, and psychiatric disorders.

Clinics and Programs

Because of the expanse of our clinical programs, our clinicians see patients at a variety of locations, such as UT Southwestern’s main campus, the UT Southwestern Medical Center at Richardson/Plano, and the UT Southwestern Medical Center at Park Cities.

Our clinicians also provide care to patients at UT Southwestern’s William P. Clements Jr. University HospitalParkland Health & Hospital System, the Dallas VA Medical Center, and Children’s Health, as well as other partner facilities.

Inpatient Care

Zale Lipshy University Hospital serves as the cornerstone of inpatient care for patients of the Peter O’Donnell Jr. Brain Institute. With 148 beds, it is among the world’s premier neurological diagnostic and treatment centers – serving as a major referral hospital for North Texas and the southwestern United States.

Zale Lipshy offers:

  • A multi-room, multi-modal neuroangiography suite and hybrid neuro-angio operating room, providing both diagnostic and minimally invasive treatment interventions
  • Advanced imaging technology, such as an Aquilion ONE 320-slice CT scanner and 3T MRI
  • A 20-bed neuroscience intensive care unit (Neuro ICU) staffed 24 hours a day, seven days a week, by physicians trained in neurology and critical care
  • The only Gamma Knife® Perfexion™ system available in North Texas, a completely robotic radiosurgical system that improves stereotactic radiosurgery options
  • An 18-bed inpatient psychiatric unit, supported by active electroconvulsive therapy (ECT) and neuromodulation programs that serve both inpatients and outpatients
  • A 36-bed inpatient rehabilitation unit

Stories and Videos

More Articles

I can think of no one whose family or friends have not been touched in one way or another by brain-related illness. The goal of the Brain Institute is to find the causes and treatment of brain and spine diseases, and the means of preventing them. UT Southwestern is uniquely positioned to meet these challenges because of our remarkably talented researchers and clinicians."

Daniel K. Podolsky, M.D.
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Research & Innovation

Neuroscience is entering a new era of innovation – where fundamental discoveries can transform basic and translational research. Ultimately, these discoveries will expand the potential to treat and prevent brain, spine, nerve, and muscle disorders.

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Education & Training

One of the key missions of the O'Donnell Brain Institute is to educate the next generation of clinicians and researchers in the neurosciences. Our faculty train residents and fellows in a wide range of specialties focused on the treatment of brain disorders and research into better treatments and preventions.

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Donate to the O’Donnell Brain Institute

Help us take the next leap forward in mastering the complexities of the brain.

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