E. Sherwood Brown, M.D., Ph.D.

Distinguished Teaching Professor

Peter O'Donnell Jr. Brain Institute

Lou and Ellen McGinley Distinguished Chair in Psychiatric Research
Aradine S. Ard Chair in Brain Science

Psychiatry

Biography

E. Sherwood Brown, M.D., Ph.D., M.B.A., is a Professor of Psychiatry with Tenure, Vice Chair for Clinical Research, Chief of the Division of Clinical Neuroscience, and Director of the Psychoneuroendocrine Research Program at UT Southwestern Medical Center. Dr. Brown received his B.A. and Ph.D. degrees in chemistry from Texas Christian University. He earned his M.D. degree at the University of Texas Medical School at Houston, and completed a psychiatry residency on the research track at UT Southwestern Medical Center, followed by a research fellowship. He also received an M.B.A. (Healthcare Leadership Concentration) from UT Dallas.

Dr. Brown is board certified in psychiatry and consultation-liaison psychiatry.

He serves on the editorial boards of several journals, including Journal of Affective Disorders, and is Editor-in-Chief of the Journal of Dual Diagnosis. He also serves as Treasurer and as a member of the board of directors and executive committee of the Academy of Consultation Liaison Psychiatry.

Dr. Brown’s research focuses on comorbidities of mood disorders including medical illness and substance abuse. He has received numerous grants from both the National Institutes of Health and private foundations, including grants from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA) examining the treatment of patients with bipolar disorder and substance use disorders, grants from the National Heart, Lung, and Blood Institute (NHLBI) examining the treatment of depressed asthma patients, grants from the National Institute of Mental Health (NIMH) exploring interventions to protect the brain from the effects of corticosteroid excess, and grants from the National Center for Complementary and Integrative Health (NCCIH) examining a novel supplements.

Dr. Brown has published well over 200 research papers, books, chapters, reviews and editorials.

Education & Training

Fellowship - UT Southwestern Medical Center (1997-1998), Research
Residency - UT Southwestern Medical Center (1994-1997), Psychiatry
Internship - UT Southwestern Medical Center (1993-1994), Psychiatry
Medical School - UT Health Science Center McGovern Medical School (1989-1993)

Professional Associations & Affiliations

Society of Biological Psychiatry
Research Society on Alcoholism
American Psychiatric Association
American College of Neuropsychopharmacology
Texas Medical Association (1993)
Academy of Consultation-Liaison Psychiatry (2005)

Honors & Awards

Lilly Fellowship Travel Award 1998, to Society of Biological Psychiatry Annual Convention
New Investigator Award 1997, from New Clinical Drug Evaluation Unit (NCDEU)
Bristol-Myers Squibb Travel Fellowship 1999, to American College of Neuropsychopharmacology (ACNP) Annual Meeting
Gerald L. Klerman Award 2002, for clinical research from National Alliance for Research in Schizophrenia and Depression (NARSAD)

Books & Publications

Publications
- Associations of a Composite Stress Measurement Tool With Cardiovascular Risk Factors and Outcomes: Findings From the Dallas Heart Study.
  Eleazu I, Ayers C, Navar AM, Salhadar K, Albert M, Carnethon M, Brown ES, Ogbu Nwobodo L, Carter S, Bess C, Powell-Wiley TM, de Lemos JA, Journal of the American Heart Association 2025 Feb e033752
- The relationship between asthma and suggested alcohol dependence and heavy alcohol use in the Cooper Center longitudinal study: The role of depressive symptom severity.
  Agarwal CD, Shuval K, Li Q, DeFina LF, Barlow CE, Khan DA, Brown ES, Journal of affective disorders 2024 Nov 370 356-361
- Depressive Symptom Severity in Mid- to Late-Life in Individuals with and without Asthma.
  Palka JM, Peacock M, Tusken M, Ibrahim M, Najjab A, Carter L, Khan DA, Brown ES, The journal of allergy and clinical immunology. In practice 2024 Sep
- IQ in high school as a predictor of midlife alcohol drinking patterns.
  Druffner N, Egan D, Ramamurthy S, O'Brien J, Davis AF, Jack J, Symester D, Thomas K, Palka JM, Thakkar VJ, Brown ES, Alcohol and alcoholism (Oxford, Oxfordshire) 2024 May 59 4
- The relationship between alcohol consumption and amygdala volume in a community-based sample.
  Pho C, Yu FF, Palka JM, Brown ES, Brain imaging and behavior 2024 Apr
- Contribution of caregiver and child anxiety and depressive symptoms to child asthma-related quality of life.
  Gwak DY, Tea JC, Fatima FN, Palka JM, Lehman H, Khan DA, Zhou H, Wood BL, Miller BD, Brown ES, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2024 Mar
- fMRI BOLD responses to film stimuli and their association with exhaled nitric oxide in asthma and health.
  Ritz T, Kroll JL, Khan DA, Yezhuvath US, Aslan S, Pinkham A, Rosenfield D, Brown ES, Psychophysiology 2024 Feb e14513
- Link between depression and bone mineral density in Cooper Center Longitudinal Study: Indirect effects of vitamin D, inflammation, and physical activity.
  Li C, Palka JM, Abdullah N, Adler-Neal A, Banner B, Efseroff B, Jones C, Clark I, Munoz-Puga M, Boswell N, Karlay B, Siddiqui R, Hergert S, Newton S, Narapureddy S, Tran V, Leonard D, DeFina LF, Barlow CE, Brown ES, Journal of affective disorders 2023 Oct 344 277-283
- Association of serotonin reuptake inhibitors with asthma control.
  Gajewski AJ, Palka JM, Raitt JM, Agarwal CD, Khan DA, Kao CH, Brown ES, Allergy and asthma proceedings 2023 Sep 44 5 354-360
- The cross-sectional relationship among omega-3 fatty acid levels, cardiorespiratory fitness, and depressive symptoms from the Cooper Center Longitudinal Study.
  Kulikova A, Palka JM, Van Enkevort EA, DeFina LF, Ly H, Sunderajan P, Willis BL, Barlow CE, Brown ES, Journal of psychosomatic research 2023 May 168 111181
- The Impact of Caregiver Depression on Child Asthma Outcomes: Pathways and Mechanisms.
  Brown ES, Palka JM, Lehman HK, Kulikova A, Khan DA, Lopez J, Antony A, Persaud D, Tiro J, Ivleva EI, Nakamura A, Patel Z, Holmes T, Humayun Q, Lloyd T, Allen K, Kaur S, Owitz MS, Pak RJ, Zablonski KG, Adragna MS, Chankalal R, Wood BL, Miller BD, The journal of allergy and clinical immunology. In practice 2023 Jan 11 1 200-209
- The Relationship Between Coronary Artery Calcification and Carotid Intima Media Thickness and Hippocampal Volume: An Analysis From the Dallas Heart Study.
  Yuan C, Palka JM, Rohatgi A, Joshi P, Berry J, Khera A, Brown ES, Journal of the Academy of Consultation-Liaison Psychiatry 2023 64 3 218-225
- Relationship between chronic obstructive pulmonary disease and cognition in an aging population.
  Shea S, Palka JM, Kulikova A, North CS, Brown ES, Journal of psychosomatic research 2022 Aug 161 111000
- A Novel Research Rotation for Residents Based on Serial Group Projects Using Existing Data Sets.
  Pershern LS, Brenner A, Kulikova A, North CS, Brown ES, Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry 2022 Jul
- Association between headache and suicidality: An analysis of universal suicide screening data at a large urban county hospital.
  Ho C, Cole L, Davis-Bordovsky K, Eichenberger A, Faubion A, Faubion M, Kendrick C, Khonsari N, Lampley J, Masood A, Nuako K, Mirabal ER, Spiller N, Walther J, Yau B, Yung M, Raitt JM, Kulikova A, North CS, Roaten K, Brown ES, Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 2022 May 34 2 114-122
- Desmosterol and 7-dehydrocholesterol concentrations in post mortem brains of depressed people: The role of trazodone.
  Cenik B, Palka JM, Thompson BM, McDonald JG, Tamminga CA, Cenik C, Brown ES, Translational psychiatry 2022 Apr 12 1 139
- A Needs Assessment Survey to Identify Barriers and Supports for Developing Scholarly Activity Among Clinician Educators.
  Robinson RJ, Brown ES, The primary care companion for CNS disorders 2022 Apr 24 3
- Anterior cingulate cortex in individuals with depressive symptoms: A structural MRI study.
  Ibrahim HM, Kulikova A, Ly H, Rush AJ, Sherwood Brown E, Psychiatry research. Neuroimaging 2022 Jan 319 111420
- Glucocorticoids for therapeutic immunosuppression: Clinical pearls for the practicing neurologist.
  Galati A, Brown ES, Bove R, Vaidya A, Gelfand J, Journal of the neurological sciences 2021 Sep 430 120004
- Multivariate Association of Child Depression and Anxiety with Asthma Outcomes.
  Kulikova A, Lopez J, Antony A, Khan DA, Persaud D, Tiro J, Ivleva EI, Nakamura A, Patel Z, Tipton S, Lloyd T, Allen K, Kaur S, Owitz MS, Pak RJ, Adragna MS, Chankalal R, Humayun Q, Lehman HK, Miller BD, Wood BL, Brown ES, The journal of allergy and clinical immunology. In practice 2021 Mar
- Comparison of hospital course and outcome in hospital-acquired vs pre-existing delirium.
  Guillory J, Fitz-Gerald C, Banik A, Sterwald C, Ashiofu E, Knox E, Muyco MA, Verlage M, Abdali A, O'Malley PW, Rezai A, Bush P, Brown ES, North CS, Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 2021 Feb 33 1 35-44
- Association of menopause symptoms with depressive symptom severity in a diverse community-based sample.
  Ji X, Singleterry S, Kulikova A, Harrison Y, Shivakumar G, Brown ES, Maturitas 2021 Jan 143 78-80
- A randomized, double-blind, placebo-controlled proof-of-concept study of ondansetron for bipolar and related disorders and alcohol use disorder.
  Sherwood Brown E, McArdle M, Palka J, Bice C, Ivleva E, Nakamura A, McNutt M, Patel Z, Holmes T, Tipton S, European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2021 Jan
- Relationship between novel inflammatory biomarker galectin-3 and depression symptom severity in a large community-based sample.
  King DR, Salako DC, Arthur-Bentil SK, Rubin AE, Italiya JB, Tan JS, Macris DG, Neely HK, Palka JM, Grodin JL, Davis-Bordovsky K, Faubion M, North CS, Brown ES, Journal of affective disorders 2020 Dec 281 384-389
- An Association Between the Inflammatory Biomarker GlycA and Depressive Symptom Severity.
  Huckvale S, Reyes S, Kulikova A, Rohatgi A, Riggs KA, Brown ES, The Journal of clinical psychiatry 2020 Nov 82 1
- The relative importance of reputation and pride as predictors of employee turnover in an academic medical center.
  Brown ES, Palka J, Helm SV, Kulikova A, Health care management review 2020 Nov
- Relationship between inflammatory biomarker galectin-3 and hippocampal volume in a community study.
  Lowther MK, Tunnell JP, Palka JM, King DR, Salako DC, Macris DG, Italiya JB, Grodin JL, North CS, Brown ES, Journal of neuroimmunology 2020 Sep 348 577386
- The Efficacy of Lidocaine in Disrupting Cocaine Cue-Induced Memory Reconsolidation.
  Becker JE, Price JL, Leonard D, Suris A, Kandil E, Shaw M, Kroener S, Brown ES, Adinoff B, Drug and alcohol dependence 2020 Jul 212 108062
- Cognitive impairment in individuals with bipolar disorder with and without comorbid alcohol and/or cocaine use disorders.
  Li C, Palka JM, Brown ES, Journal of affective disorders 2020 Jul 272 355-362
- Association of depressive symptom severity with coronary artery calcium: The Dallas heart study.
  Khan A, Palka J, Joshi PH, Khera A, Brown ES, Journal of affective disorders 2020 Jul 276 267-271
- The Relationship Between State Mental Health Agency and Medicaid Spending with Outcomes.
  Robinson RJ, Palka JM, Brown ES, Community mental health journal 2020 Jun
- Association between C reactive protein and depression in a population of healthy adults: the Cooper Center Longitudinal Study.
  Khan A, Leonard D, Defina L, Barlow CE, Willis B, Brown ES, Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2020 Mar
- Personality traits and risk of lifetime asthma diagnosis.
  Najjab A, Palka JM, Brown ES, Journal of psychosomatic research 2020 Feb 131 109961
- Association of Megestrol Use With the Development of New Psychiatric Diagnoses.
  Ramamurthy S, Van Enkevort E, Xie D, Palka J, Brown ES, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2020 Jan
- The Relationship Between Cumulative Exogenous Corticosteroid Exposure and Volumes of Hippocampal Subfields and Surrounding Structures.
  Nguyen DM, Yassa MA, Tustison NJ, Roberts JM, Kulikova A, Nakamura A, Ivleva EI, Van Enkevort E, Brown ES, Journal of clinical psychopharmacology 2019 Nov/Dec 39 6 653-657
- Trust in Physicians and Regional Brain Volumes: A Population-Based Study.
  Sadhu M, Jalalizadeh B, Fritz A, Nicholson TF, Garcia R, Lampley S, Rain M, Van Enkevort E, Brown ES, The primary care companion for CNS disorders 2019 Oct 21 5
- Subcortical gray matter volumes in asthma: associations with asthma duration, control, and anxiety.
  Ritz T, Kroll JL, Aslan S, Janssens T, Khan DA, Pinkham AE, Brown ES, Brain imaging and behavior 2019 Sep
- Cortisol awakening response and fractional exhaled nitric oxide in asthma.
  Kroll JL, Brown ES, Ritz T, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2019 Jun
- A randomized trial of an NMDA receptor antagonist for reversing corticosteroid effects on the human hippocampus.
  Brown ES, Kulikova A, Van Enkevort E, Nakamura A, Ivleva EI, Tustison NJ, Roberts J, Yassa MA, Choi C, Frol A, Khan DA, Vazquez M, Holmes T, Malone K, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2019 Jun
- Effect of Selective Serotonin Reuptake Inhibitors on Healthcare Utilization in Patients with Post-Traumatic Stress Disorder and Alcohol Use Disorder.
  Naglich AC, Bozeman S, Brown ES, Adinoff B, Alcohol and alcoholism (Oxford, Oxfordshire) 2019 Jun
- Relationship between trust in neighbors and regional brain volumes in a population-based study.
  Sadhu M, Nicholson TF, Garcia R, Lampley S, Rain M, Fritz A, Jalalizadeh B, Van Enkevort E, Palka J, Brown ES, Psychiatry research. Neuroimaging 2019 Apr 286 11-17
- From the Editors.
  Green AI, Brown ES, Journal of dual diagnosis 2019 Mar 1
- Central Nervous System Signatures of Affect in Asthma: Associations with Emotion-Induced Bronchoconstriction, Airway Inflammation, and Asthma Control.
  Ritz T, Kroll JL, Patel SV, Chen JR, Yezhuvath US, Aslan S, Khan DA, Pinkham AE, Rosenfield D, Brown ES, Journal of applied physiology (Bethesda, Md. : 1985) 2019 Mar
- Association between telomere length and cognitive ability in a community-based sample.
  Kaja R, Reyes SM, Rossetti HC, Brown ES Neurobiology of aging 2019 Mar 75 51-53
- A pilot study of brexpiprazole for bipolar depression.
  Brown ES, Khaleghi N, Van Enkevort E, Ivleva E, Nakamura A, Holmes T, Mason BL, Escalante C Journal of affective disorders 2019 Feb 249 315-318
- A Randomized, Double-Blind, Placebo-Controlled Trial of Citicoline in Patients with Alcohol Use Disorder.
  Brown ES, Van Enkevort E, Kulikova A, Escalante C, Nakamura A, Ivleva EI, Holmes T Alcoholism, clinical and experimental research 2019 Feb 43 2 317-323
- A randomized, double-blind, placebo-controlled trial of lamotrigine for prescription corticosteroid effects on the human hippocampus.
  Brown ES, Sayed N, Choi C, Tustison N, Roberts J, Yassa MA, Van Enkevort E, Nakamura A, Ivleva EI, Sunderajan P, Khan DA, Vazquez M, McEwen B, Kulikova A, Frol AB, Holmes T European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2019 Jan
- Gabapentin Enacarbil Extended-Release for Alcohol Use Disorder: A Randomized, Double-Blind, Placebo-Controlled, Multisite Trial Assessing Efficacy and Safety.
  Falk DE, Ryan ML, Fertig JB, Devine EG, Cruz R, Brown ES, Burns H, Salloum IM, Newport DJ, Mendelson J, Galloway G, Kampman K, Brooks C, Green AI, Brunette MF, Rosenthal RN, Dunn KE, Strain EC, Ray L, Shoptaw S, Ait-Daoud Tiouririne N, Gunderson EW, Ransom J, Scott C, Leggio L, Caras S, Mason BJ, Litten RZ Alcoholism, clinical and experimental research 2019 Jan 43 1 158-169
- Human Safety and Pharmacokinetics Study of Orally Administered Icariin: Randomized, Double-Blind, Placebo-Controlled Trial
  E. Sherwood Brown, Collette Bice, William C. Putnam, Richard Leff, Alexandra Kulikova, Alyson Nakamura, Elena I. Ivleva, Erin Van Enkevort, Traci Holmes, and Nyokabi Miingi Natural Product Communications 2019 14 6 1-6
- Systematic review of preclinical, clinical, and post-marketing evidence of bupropion misuse potential.
  Naglich AC, Brown ES, Adinoff B The American journal of drug and alcohol abuse 2019 Jan 1-14
- Relationship between depressive symptom severity and amygdala volume in a large community-based sample.
  Daftary S, Van Enkevort E, Kulikova A, Legacy M, Brown ES Psychiatry research. Neuroimaging 2019 Jan 283 77-82
- Megestrol Acetate Induces Declarative Memory Changes and Cortisol Suppression in Healthy Volunteers.
  Mason BL, Ivleva EI, Van Enkevort E, Nakamura A, Brown ES Dementia and geriatric cognitive disorders 2018 Oct 46 3-4 186-192
- The Effects of Caregiver Depression on Childhood Asthma: Pathways and Mechanisms.
  Wood BL, Brown ES, Lehman HK, Khan DA, Lee MJ, Miller BD Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2018 Jul
- Association of Biological Markers of Alcohol Consumption and Self-Reported Drinking with Hippocampal Volume in a Population-Based Sample of Adults.
  Naglich A, Van Enkevort E, Adinoff B, Brown ES Alcohol and alcoholism (Oxford, Oxfordshire) 2018 Jun
- A Randomized, Double-Blind, Placebo-Controlled Trial of Escitalopram in Patients with Asthma and Major Depressive Disorder.
  Brown ES, Sayed N, Van Enkevort E, Kulikova A, Nakamura A, Khan DA, Ivleva EI, Sunderajan P, Bender BG, Holmes T The journal of allergy and clinical immunology. In practice 2018 Feb
- Hippocampal metabolites in asthma and their implications for cognitive function.
  Kroll JL, Steele AM, Pinkham AE, Choi C, Khan DA, Patel SV, Chen JR, Aslan S, Sherwood Brown E, Ritz T NeuroImage. Clinical 2018 19 213-221
- The relationship between asthma and depression in a community-based sample.
  Akula M, Kulikova A, Khan DA, Brown ES The Journal of asthma : official journal of the Association for the Care of Asthma 2018 Jan 1-7
- Neurosteroid Levels in Patients With Bipolar Disorder and a History of Cannabis Use Disorders.
  Mason BL, Van Enkevort E, Filbey F, Marx CE, Park J, Nakamura A, Sunderajan P, Brown ES Journal of clinical psychopharmacology 2017 Oct
- Pharmacological Treatment of Bipolar Disorder with Comorbid Alcohol Use Disorder.
  Naglich A, Adinoff B, Brown ES CNS drugs 2017 Aug 31 8 665-674
- Association Between Bone Mineral Density and Depressive Symptoms in a Population-Based Sample.
  Hlis RD, McIntyre RS, Maalouf NM, Van Enkevort E, Brown ES The Journal of clinical psychiatry 2017 Aug
- Microtubule associated protein 2 in bipolar depression: Impact of pregnenolone.
  Daftary S, Yon JM, Choi EK, Kim YB, Bice C, Kulikova A, Park J, Sherwood Brown E Journal of affective disorders 2017 Apr 218 49-52
- Relationship Between Current Depressive Symptoms and Telomere Length in a Large, Multiethnic Sample.
  Wignall ND, Deschner M, Evans HM, Brown ES The Journal of clinical psychiatry 2017 Mar
- Management of comorbid bipolar disorder and substance use disorders.
  Salloum IM, Brown ES The American journal of drug and alcohol abuse 2017 Mar 1-11
- Evaluation of the value of team-based psychiatric consultation in a general hospital setting.
  Orsak C, Thomas A, Bush P, Brown ES International journal of psychiatry in medicine 2017 Jan 91217417749798
- Plasma sterols and depressive symptom severity in a population-based cohort.
  Cenik B, Cenik C, Snyder MP, Brown ES PloS one 2017 12 9 e0184382
- Adrenocortical sensitivity, moderated by ongoing stress, predicts drinking intensity in alcohol-dependent men.
  Adinoff B, Leonard D, Price J, Javors MA, Walker R, Brown ES, Xiao H, Rao U Psychoneuroendocrinology 2016 Nov 76 67-76
- Impact of Stimulant Medication Use on Heart Rate and Systolic Blood Pressure During Submaximal Exercise Treadmill Testing in Adolescents.
  Westover AN, Nakonezny PA, Adinoff B, Brown ES, Halm EA Journal of child and adolescent psychopharmacology 2016 Sep
- Expanded conceptualization of multimorbidity to encompass substance use disorders and other psychiatric illness.
  North CS, Brown ES, Pollio DE Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 2016 Aug 28 3 182-8
- Development of a Glucocorticoid Toxicity Index (GTI) using multicriteria decision analysis.
  Miloslavsky EM, Naden RP, Bijlsma JW, Brogan PA, Brown ES, Brunetta P, Buttgereit F, Choi HK, DiCaire JF, Gelfand JM, Heaney LG, Lightstone L, Lu N, Murrell DF, Petri M, Rosenbaum JT, Saag KS, Urowitz MB, Winthrop KL, Stone JH Annals of the rheumatic diseases 2016 Jul
- Temporal Association Between Nonfatal Self-Directed Violence and Tree and Grass Pollen Counts.
  Jeon-Slaughter H, Claassen CA, Khan DA, Mihalakos P, Lee KB, Brown ES The Journal of clinical psychiatry 2016 Jun
- Hippocampal Volume in Patients with Asthma: Results from the Dallas Heart Study.
  Carlson SM, Kim J, Khan DA, King K, Lucarelli RT, McColl R, Peshock R, Brown ES The Journal of asthma : official journal of the Association for the Care of Asthma 2016 May 0
- An open-label pilot study of icariin for co-morbid bipolar and alcohol use disorder.
  Xiao H, Wignall N, Brown ES The American journal of drug and alcohol abuse 2016 Jan 1-6
- Historical Underpinnings of Bipolar Disorder Diagnostic Criteria.
  Mason BL, Brown ES, Croarkin PE Behavioral sciences (Basel, Switzerland) 2016 6 3
- A Randomized, Double-Blind, Placebo-Controlled Trial of Citicoline for Cocaine Dependence in Bipolar I Disorder.
  Brown ES, Todd JP, Hu LT, Schmitz JM, Carmody TJ, Nakamura A, Sunderajan P, Rush AJ, Adinoff B, Bret ME, Holmes T, Lo A The American journal of psychiatry 2015 May appiajp201514070857
- Exercise outcomes in prevalent users of stimulant medications.
  Westover AN, Nakonezny PA, Barlow CE, Vongpatanasin W, Adinoff B, Brown ES, Mortensen EM, Halm EA, DeFina LF Journal of psychiatric research 2015 May 64 32-9
- Hippocampal Volume in Healthy Controls Given 3-Day Stress Doses of Hydrocortisone.
  Brown ES, Jeon-Slaughter H, Lu H, Jamadar R, Issac S, Shad M, Denniston D, Tamminga C, Nakamura A, Thomas BP Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014 Nov
- Factitious angioedema: a mimic of refractory "angioedema".
  Feldman MF, Khan DA, Brown ES, Bernstein JA The journal of allergy and clinical immunology. In practice 2014 Nov-Dec 2 6 795-7
- Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects.
  Judd LL, Schettler PJ, Brown ES, Wolkowitz OM, Sternberg EM, Bender BG, Bulloch K, Cidlowski JA, Ronald de Kloet E, Fardet L, Joëls M, Leung DY, McEwen BS, Roozendaal B, Van Rossum EF, Ahn J, Brown DW, Plitt A, Singh G The American journal of psychiatry 2014 Oct 171 10 1045-51
- Citicoline in addictive disorders: a review of the literature.
  Wignall ND, Brown ES The American journal of drug and alcohol abuse 2014 Jul 40 4 262-8
- The effect of cognitive functioning on treatment attendance and adherence in comorbid bipolar disorder and cocaine dependence.
  Fagan CS, Carmody TJ, McClintock SM, Suris A, Nakamura A, Jeon-Slaughter H, Lo A, Brown ES Journal of substance abuse treatment 2014 Jul
- A randomized, double-blind, placebo-controlled trial of quetiapine in patients with bipolar disorder, mixed or depressed phase, and alcohol dependence.
  Brown ES, Davila D, Nakamura A, Carmody TJ, Rush AJ, Lo A, Holmes T, Adinoff B, Caetano R, Swann AC, Sunderajan P, Bret ME Alcoholism, clinical and experimental research 2014 Jul 38 7 2113-8
- A Randomized, Double-Blind, Placebo-Controlled Trial of Pregnenolone for Bipolar Depression.
  Brown ES, Park J, Marx CE, Hynan LS, Gardner C, Davila D, Nakamura A, Sunderajan P, Lo A, Holmes T Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014 Jun
- Asthma and depression: the Cooper Center Longitudinal Study.
  Trojan TD, Khan DA, Defina LF, Akpotaire O, Goodwin RD, Brown ES Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2014 Mar
- Association of Depressive Symptoms with Hippocampal Volume in 1936 Adults.
  Brown ES, Hughes CW, McColl R, Peshock R, King KS, Rush AJ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013 Oct
- The relationship between asthma and self-reported anxiety in a predominantly healthy adult population.
  Gada E, Khan DA, Defina LF, Brown ES Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2013 Sep
- A comparison of clinician-rated neuropsychological and self-rated cognitive assessments in patients with asthma and rheumatologic disorders.
  Frol AB, Vasquez A, Getahun Y, Pacheco M, Khan DA, Brown ES Allergy and asthma proceedings : the official journal of regional and state allergy societies 2013 Mar 34 2 170-5
- Relationship between asthma and cognition: the Cooper Center Longitudinal Study.
  Caldera-Alvarado G, Khan DA, Defina LF, Pieper A, Brown ES Allergy 2013 Feb
- A randomized, placebo-controlled proof-of-concept, crossover trial of phenytoin for hydrocortisone-induced declarative memory changes.
  Brown ES, Lu H, Denniston D, Uh J, Thomas BP, Carmody TJ, Auchus RJ, Diaz-Arrastia R, Tamminga C Journal of affective disorders 2013 Feb
- Nanofiltered C1 esterase inhibitor (human) for hereditary angioedema attacks in pregnant women.
  Baker JW, Craig TJ, Riedl MA, Banerji A, Fitts D, Kalfus IN, Uknis ME, Allergy and asthma proceedings 2013 34 2 162-9
- A randomized, double-blind, placebo-controlled trial of citicoline for bipolar and unipolar depression and methamphetamine dependence.
  Brown ES, Gabrielson B Journal of affective disorders 2012 Dec 143 1-3 257-60
- A randomized, double-blind, placebo-controlled, trial of lamotrigine therapy in bipolar disorder, depressed or mixed phase and cocaine dependence.
  Brown ES, Sunderajan P, Hu LT, Sowell SM, Carmody TJ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012 Oct 37 11 2347-54
- An epidemiological approach to "steroid psychosis".
  Brown ES The American journal of psychiatry 2012 May 169 5 447-9
- Relationship between serum homocysteine levels and depressive symptoms: the Cooper Center Longitudinal Study.
  Gu P, DeFina LF, Leonard D, John S, Weiner MF, Brown ES The Journal of clinical psychiatry 2012 May 73 5 691-5
- T2 measurement of J-coupled metabolites in the human brain at 3T.
  Ganji SK, Banerjee A, Patel AM, Zhao YD, Dimitrov IE, Browning JD, Brown ES, Maher EA, Choi C NMR in biomedicine 2012 Apr 25 4 523-9
- Depression, anxiety, and COPD: the unexamined role of nicotine dependence.
  Goodwin RD, Lavoie KL, Lemeshow AR, Jenkins E, Brown ES, Fedoronko DA Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012 Feb 14 2 176-83
- Escitalopram for severe asthma and major depressive disorder: a randomized, double-blind, placebo-controlled proof-of-concept study.
  Brown ES, Howard C, Khan DA, Carmody TJ Psychosomatics 2012 Jan-Feb 53 1 75-80
- Association between low serum 25-hydroxyvitamin D and depression in a large sample of healthy adults: the Cooper Center longitudinal study.
  Hoang MT, Defina LF, Willis BL, Leonard DS, Weiner MF, Brown ES Mayo Clinic proceedings. Mayo Clinic 2011 Nov 86 11 1050-5
- Cognition and dorsolateral prefrontal cortex volume in corticosteroid-treated patients given lamotrigine
  Saira Husain, Samuel Kuzminski, Mujeeb U. Shad, Barry Gabrielson, Mary E. Bret,I. Julian Osuji, E. Sherwood Brown Stress and Health 2011 27 1 18-22
- Effects of lamotrigine on hippocampal activation in corticosteroid-treated patients.
  Brown ES, Zaidel L, Allen G, McColl R, Vazquez M, Ringe WK Journal of affective disorders 2010 Nov 126 3 415-9
- A double-blind, placebo-controlled study with quetiapine as adjunct therapy with lithium or divalproex in bipolar I patients with coexisting alcohol dependence.
  Stedman M, Pettinati HM, Brown ES, Kotz M, Calabrese JR, Raines S Alcoholism, clinical and experimental research 2010 Oct 34 10 1822-31
- Randomized, double-blind, placebo-controlled trial of acetaminophen for preventing mood and memory effects of prednisone bursts.
  Brown ES, Denniston D, Gabrielson B, Khan DA, Khanani S, Desai S Allergy and asthma proceedings : the official journal of regional and state allergy societies 2010 Jul 31 4 331-6
- Pregnenolone for cognition and mood in dual diagnosis patients.
  Osuji IJ, Vera-Bolaños E, Carmody TJ, Brown ES Psychiatry research 2010 Jul 178 2 309-12
- Association of race and ethnicity with withdrawal symptoms, attrition, opioid use, and side-effects during buprenorphine therapy.
  Brown ES, Tirado C, Minhajuddin A, Hillhouse M, Adinoff B, Ling W, Doraimani G, Thomas C Journal of ethnicity in substance abuse 2010 Apr 9 2 106-14
- A Pilot Study of Quetiapine in Patients With Bipolar Disorder and Cocaine Dependence
  E. Sherwood Brown, Barry Gabrielson, Phillip Gu Journal of Dual Diagnosis 2010 6 1 16-24
- A randomized, double-blind, placebo-controlled pilot study of naltrexone in outpatients with bipolar disorder and alcohol dependence.
  Brown ES, Carmody TJ, Schmitz JM, Caetano R, Adinoff B, Swann AC, John Rush A Alcoholism, clinical and experimental research 2009 Nov 33 11 1863-9
- Effects of glucocorticoids on mood, memory, and the hippocampus. Treatment and preventive therapy.
  Brown ES Annals of the New York Academy of Sciences 2009 Oct 1179 41-55
- Attenuation of amygdala atrophy with lamotrigine in patients receiving corticosteroid therapy.
  Desai S, Khanani S, Shad MU, Brown ES Journal of clinical psychopharmacology 2009 Jun 29 3 284-7
- Attrition factors in clinical trials of comorbid bipolar and substance-related disorders.
  Nomamiukor N, Brown ES Journal of affective disorders 2009 Jan 112 1-3 284-8
- Randomized, placebo-controlled, crossover trial of memantine for cognitive changes with corticosteroid therapy.
  Brown ES, Vazquez M, Nakamura A Biological psychiatry 2008 Oct 64 8 727-9
- Antidepressant treatment of caregivers of children with asthma.
  Brown ES, Gan V, Jeffress J, Wood BL, Miller BD, Khan DA Psychosomatics 2008 Sep-Oct 49 5 420-5
- Attenuation of the effects of corticosteroids on declarative memory with lamotrigine.
  Brown ES, Wolfshohl J, Shad MU, Vazquez M, Osuji IJ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008 Sep 33 10 2376-83
- A randomized, double-blind, placebo-controlled add-on trial of quetiapine in outpatients with bipolar disorder and alcohol use disorders.
  Brown ES, Garza M, Carmody TJ The Journal of clinical psychiatry 2008 May 69 5 701-5
- Amygdala volume in patients receiving chronic corticosteroid therapy.
  Brown ES, Woolston DJ, Frol AB Biological psychiatry 2008 Apr 63 7 705-9
- Declarative memory in patients with bipolar disorder and stimulant abuse given lamotrigine
  I. Julian Osuji, Elizabeth Tucker, E. Sherwood Brown Journal of Dual Diagnosis 2008 4 3 303-313
- A randomized, placebo-controlled trial of citicoline add-on therapy in outpatients with bipolar disorder and cocaine dependence.
  Brown ES, Gorman AR, Hynan LS Journal of clinical psychopharmacology 2007 Oct 27 5 498-502
- Impact of levetiracetam on mood and cognition during prednisone therapy.
  Brown ES, Frol AB, Khan DA, Larkin GL, Bret ME European psychiatry : the journal of the Association of European Psychiatrists 2007 Oct 22 7 448-52
- Comorbid disorders in patients with bipolar disorder and concomitant substance dependence.
  Mitchell JD, Brown ES, Rush AJ Journal of affective disorders 2007 Sep 102 1-3 281-7
- Effects of chronic prednisone therapy on mood and memory.
  Brown ES, Vera E, Frol AB, Woolston DJ, Johnson B Journal of affective disorders 2007 Apr 99 1-3 279-83
- Bupropion in the treatment of outpatients with asthma and major depressive disorder.
  Brown ES, Vornik LA, Khan DA, Rush AJ International journal of psychiatry in medicine 2007 37 1 23-8
- Psychiatric symptomatology and disorders in caregivers of children with asthma.
  Brown ES, Gan V, Jeffress J, Mullen-Gingrich K, Khan DA, Wood BL, Miller BD, Gruchalla R, Rush AJ Pediatrics 2006 Dec 118 6 e1715-20
- Age at onset of major depression in inner-city adults with asthma.
  Solis OL, Khan DA, Brown ES Psychosomatics 2006 Jul-Aug 47 4 330-2
- Effect of two prednisone exposures on mood and declarative memory.
  Brown ES, Beard L, Frol AB, Rush AJ Neurobiology of learning and memory 2006 Jul 86 1 28-34
- Lamotrigine for bipolar disorder and comorbid cocaine dependence: a replication and extension study.
  Brown ES, Perantie DC, Dhanani N, Beard L, Orsulak P, Rush AJ Journal of affective disorders 2006 Jul 93 1-3 219-22
- Impulsivity in patients with bipolar disorder and cocaine or amphetamine dependence given lamotrigine
  Akingbala F, Dhanani N, Brown ES Journal of Dual Diagnosis 2006 2 3 73-83
- Naltrexone in patients with bipolar disorder and alcohol dependence.
  Brown ES, Beard L, Dobbs L, Rush AJ Depression and anxiety 2006 23 8 492-5
- A randomized trial of citalopram versus placebo in outpatients with asthma and major depressive disorder: a proof of concept study.
  Brown ES, Vigil L, Khan DA, Liggin JD, Carmody TJ, Rush AJ Biological psychiatry 2005 Dec 58 11 865-70
- Switching outpatients with bipolar or schizoaffective disorders and substance abuse from their current antipsychotic to aripiprazole.
  Brown ES, Jeffress J, Liggin JD, Garza M, Beard L The Journal of clinical psychiatry 2005 Jun 66 6 756-60
- Effect of phenytoin on mood and declarative memory during prescription corticosteroid therapy.
  Brown ES, Stuard G, Liggin JD, Hukovic N, Frol A, Dhanani N, Khan DA, Jeffress J, Larkin GL, McEwen BS, Rosenblatt R, Mageto Y, Hanczyc M, Cullum CM Biological psychiatry 2005 Mar 57 5 543-8
- Comparison of the Internal State Scale to Clinician-Administered Assessments in Patients with Bipolar Disorder and Alcohol Abuse or Dependence
  Rattapol Srisinroongruang, Nafisa Dhanani, Mark S. Bauer, E. Sherwood Brown Journal of Dual Diagnosis 2005 1 3 61-69
- Examination of a possible interaction between prednisone and newer antidepressants
  Brown CK, Meeker G, Brown ES Primary Care and Community Psychiatry 2005 10 4 143-147
- An open-label trial of olanzapine for corticosteroid-induced mood symptoms.
  Brown ES, Chamberlain W, Dhanani N, Paranjpe P, Carmody TJ, Sargeant M Journal of affective disorders 2004 Dec 83 2-3 277-81
- Assessment of mood states in patients receiving long-term corticosteroid therapy and in controls with patient-rated and clinician-rated scales.
  Bolanos SH, Khan DA, Hanczyc M, Bauer MS, Dhanani N, Brown ES Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004 May 92 5 500-5
- Hippocampal volume, spectroscopy, cognition, and mood in patients receiving corticosteroid therapy.
  Brown ES, J Woolston D, Frol A, Bobadilla L, Khan DA, Hanczyc M, Rush AJ, Fleckenstein J, Babcock E, Cullum CM Biological psychiatry 2004 Mar 55 5 538-45
- Drug dreams in outpatients with bipolar disorder and cocaine dependence.
  Yee T, Perantie DC, Dhanani N, Brown ES The Journal of nervous and mental disease 2004 Mar 192 3 238-42
- Association of depression with medical illness: does cortisol play a role?
  Brown ES, Varghese FP, McEwen BS Biological psychiatry 2004 Jan 55 1 1-9
- Cocaine and amphetamine use in patients with psychiatric illness: a randomized trial of typical antipsychotic continuation or discontinuation.
  Brown ES, Nejtek VA, Perantie DC, Rajan Thomas N, Rush AJ Journal of clinical psychopharmacology 2003 Aug 23 4 384-8
- Open-label nefazodone in patients with a major depressive episode and alcohol dependence.
  Brown ES, Bobadilla L, Nejtek VA, Perantie D, Dhillon H, Frol A Progress in neuro-psychopharmacology & biological psychiatry 2003 Jun 27 4 681-5
- Effect of lamotrigine on mood and cognition in patients receiving chronic exogenous corticosteroids.
  Brown ES, Frol A, Bobadilla L, Nejtek VA, Perantie DC, Dhillon H Psychosomatics 2003 May-Jun 44 3 204-8
- Texas Medication Algorithm Project, phase 3 (TMAP-3): clinical results for patients with a history of mania.
  Suppes T, Rush AJ, Dennehy EB, Crismon ML, Kashner TM, Toprac MG, Carmody TJ, Brown ES, Biggs MM, Shores-Wilson K, Witte BP, Trivedi MH, Miller AL, Altshuler KZ, Shon SP The Journal of clinical psychiatry 2003 Apr 64 4 370-82
- Clinician ratings vs. global ratings of symptom severity: a comparison of symptom measures in the bipolar disorder module, phase II, Texas Medication Algorithm Project.
  Brown ES, Rush AJ, Biggs MM, Shores-Wilson K, Carmody TJ, Suppes T Psychiatry research 2003 Feb 117 2 167-75
- Lamotrigine in patients with bipolar disorder and cocaine dependence.
  Brown ES, Nejtek VA, Perantie DC, Orsulak PJ, Bobadilla L The Journal of clinical psychiatry 2003 Feb 64 2 197-201
- Quetiapine in bipolar disorder and cocaine dependence.
  Brown ES, Nejtek VA, Perantie DC, Bobadilla L Bipolar disorders 2002 Dec 4 6 406-11
- Depressive Symptoms in Inner-City Children With Asthma.
  Morrison KM, Goli A, Van Wagoner J, Brown ES, Khan DA Primary care companion to the Journal of clinical psychiatry 2002 Oct 4 5 174-177
- A comparison of single-item visual analog scales with a multiitem likert-type scale for assessment of cocaine craving in persons with bipolar disorder
  Jennifer W. Lee, E. Sherwood Brown, Dana C. Perantie, Leonardo Bobadilla Addictive Disorders and their Treatment 2002 1 4 140-142
- The Hypothalamic-Pituitary-Adrenal Axis in Major Depressive Disorder: A Brief Primer for Primary Care Physicians.
  Varghese FP, Brown ES Primary care companion to the Journal of clinical psychiatry 2001 Aug 3 4 151-155
- Prevalence of mood disorders and relationship to asthma severity in patients at an inner-city asthma clinic.
  Nejtek VA, Brown ES, Khan DA, Moore JJ, Van Wagner J, Perantie DC Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2001 Aug 87 2 129-33
- Drug abuse and bipolar disorder: comorbidity or misdiagnosis?
  Sherwood Brown E, Suppes T, Adinoff B, Rajan Thomas N Journal of affective disorders 2001 Jul 65 2 105-15
- Atypical antipsychotics in bipolar and schizoaffective disorders.
  Brown ES, Thomas NR, Carmody T, Mahadi S, Nejtek VA Pharmacopsychiatry 2001 Mar 34 2 80-1
- Mood and Cognitive Changes During Systemic Corticosteroid Therapy.
  Brown ES, Chandler PA Primary care companion to the Journal of clinical psychiatry 2001 Feb 3 1 17-21
- Depression in Asthma: Prevalence and Clinical Implications.
  Zielinski TA, Brown ES, Nejtek VA, Khan DA, Moore JJ, Rush AJ Primary care companion to the Journal of clinical psychiatry 2000 Oct 2 5 153-158
- Efficacy of divalproex therapy for schizoaffective disorder.
  Bogan AM, Brown ES, Suppes T Journal of clinical psychopharmacology 2000 Oct 20 5 520-2
- Open-label adjunctive topiramate in the treatment of bipolar disorders.
  McElroy SL, Suppes T, Keck PE, Frye MA, Denicoff KD, Altshuler LL, Brown ES, Nolen WA, Kupka RW, Rochussen J, Leverich GS, Post RM Biological psychiatry 2000 Jun 47 12 1025-33
- Comparison of the internal state scale to clinician-administered scales in asthma patients receiving corticosteroid therapy.
  Brown ES, Bauer MS, Suppes T, Khan DA, Carmody T General hospital psychiatry 2000 May-Jun 22 3 180-3
- Switching outpatients between atypical antipsychotics.
  Bogan AM, Shellhorn E, Brown ES, McDanald C, Suppes T Progress in neuro-psychopharmacology & biological psychiatry 2000 Feb 24 2 351-5
- The psychiatric sequelae of civilian trauma.
  Brown ES, Fulton MK, Wilkeson A, Petty F Comprehensive psychiatry 2000 Jan-Feb 41 1 19-23
- Psychiatric diagnoses in inner city outpatients with moderate to severe asthma.
  Brown ES, Khan DA, Mahadi S International journal of psychiatry in medicine 2000 30 4 319-27
- Depressive symptoms and functioning in asthma patients
  E. Sherwood Brown, D. A. Khan, V. A. Nejtek, N. Rajan Thomas, S. F. Mahadi Primary Care Psychiatry 2000 4 6 155-161
- The psychiatric side effects of corticosteroids.
  Brown ES, Khan DA, Nejtek VA Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 1999 Dec 83 6 Pt 1 495-503; quiz 503-4
- Clozapine associated with decreased suicidality in bipolar disorder: a case report.
  Vangala VR, Brown ES, Suppes T Bipolar disorders 1999 Dec 1 2 123-4
- Antidepressant-induced bruxism successfully treated with gabapentin.
  Brown ES, Hong SC Journal of the American Dental Association (1939) 1999 Oct 130 10 1467-9
- Hippocampal remodeling and damage by corticosteroids: implications for mood disorders.
  Brown ES, Rush AJ, McEwen BS Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999 Oct 21 4 474-84
- Gabapentin in the acute treatment of refractory bipolar disorder.
  Altshuler LL, Keck PE, McElroy SL, Suppes T, Brown ES, Denicoff K, Frye M, Gitlin M, Hwang S, Goodman R, Leverich G, Nolen W, Kupka R, Post R Bipolar disorders 1999 Sep 1 1 61-5
- Lamotrigine for the treatment of bipolar disorder: a clinical case series.
  Suppes T, Brown ES, McElroy SL, Keck PE, Nolen W, Kupka R, Frye M, Denicoff KD, Altshuler L, Leverich GS, Post RM Journal of affective disorders 1999 Apr 53 1 95-8
- Droperidol in the interim management of severe mania: case reports and literature review.
  Brown ES, Dilsaver SC, Bowers TC, Swann AC Clinical neuropharmacology 1998 Sep-Oct 21 5 316-8
- Gastrointestinal side-effects after switch to generic valproic acid.
  Sherwood Brown E, Shellhorn E, Suppes T, Pharmacopsychiatry 1998 May 31 3 114
- Mood symptoms during corticosteroid therapy: a review.
  Brown ES, Suppes T Harvard review of psychiatry 1998 Jan-Feb 5 5 239-46
- Chemical dependence involving glucocorticoids.
  Brown ES Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 1997 Sep 9 3 185-7
- Delusional electronic dental implant: case reports and literature review.
  Brown ES, Lambert MT The Journal of nervous and mental disease 1995 Sep 183 9 603-4
- Depressive mania: response of residual depression to bupropion.
  Brown ES, Dilsaver SC, Shoaib AM, Swann AC Biological psychiatry 1994 Apr 35 7 493-4
- Recurrent miscarriage--outcome after supportive care in early pregnancy.
  Liddell HS, Pattison NS, Zanderigo A, The Australian & New Zealand journal of obstetrics & gynaecology 1991 Nov 31 4 320-2
- Sequence and secondary structure of chloroplast 16S rRNA from the chromophyte alga Olisthodiscus luteus, as inferred from the gene sequence.
  Delaney TP, Cattolico RA, Nucleic acids research 1991 Nov 19 22 6328

Research

Treatment of patients with bipolar disorder and substance abuse
Treatment of bipolar depression
Effects of corticosteroids on the hippocampus
Depression in asthma patients