- Medical School - Johns Hopkins University (1985-1990)
- Internship - Greater Baltimore Medical Center (1990-1991), Internal Medicine
- Residency - Wills Eye Hospital (1991-1994), Ophthalmology
- Fellowship - Bascom Palmer Eye Institute (1994-1995), Retina
- Fellowship - University of California San Francisco (1995-1996), Ocular Oncology Pathology
- Research Fellowship - Washington University School of Medicine (1996-1999), Molecular Oncology

J. William Harbour, M.D.
- The David Bruton, Jr. Chair in Ophthalmology
- Ophthalmology
- Ocular oncology
- Retinoblastoma
Biography
J. William Harbour, M.D., is Professor and Chair of the Department of Ophthalmology at UT Southwestern Medical Center. He specializes in ocular oncology.
Dr. Harbour earned his medical degree at Johns Hopkins University and completed a residency in ophthalmology at the Wills Eye Hospital of Thomas Jefferson University. He received advanced training through a fellowship in vitreoretinal diseases and surgery at the Bascom Palmer Eye Institute of the University of Miami, a fellowship in ocular oncology at the University of California, San Francisco, and research training in molecular oncology at Washington University in St. Louis.
Certified by the American Board of Ophthalmology, he joined the UT Southwestern faculty in 2021.
Previously, Dr. Harbour held the Dr. Mark J. Daily, M.D., Endowed Chair at the Bascom Palmer Eye Institute, where he also served as Director of Ocular Oncology and Vice Chair for Translational Research. He also served as Associate Director for Basic Science at the Sylvester Comprehensive Cancer Center of the University of Miami.
Dr. Harbour’s clinical interests focus on ocular tumors such as uveal melanoma, retinoblastoma, and lymphoma. He has trained many residents and fellows and pioneered new surgical methods in fine needle biopsy, laser treatment, and brachytherapy of ocular tumors. He also has been awarded patents for innovations in genetic prognostic testing for uveal melanoma.
His research interests include the use of genetic and genomic technologies to better understand, diagnose, and treat eye cancers. His team discovered three of the most important genomic drivers of metastasis in uveal melanoma, as well as key genomic events in retinoblastoma. His contributions to the field have been recognized by the Association for Research in Vision and Ophthalmology’s Cogan Award and the Macula Society’s Paul Henkind and Rosenthal Awards, among many others.
Dr. Harbour has delivered more than 300 invited scientific lectures and published more than 200 peer-reviewed scientific articles and book chapters.
He is an Associate Editor for Melanoma Research and has served on the editorial boards of Archives of Ophthalmology, Translational Vision Science & Technology, Melanoma Management, Expert Review of Ophthalmology, and Faculty of 1000.
Dr. Harbour is a member of numerous professional organizations, including the Association of American Physicians, American Academy of Ophthalmology, American Association for Cancer Research, and American Association of Ophthalmic Oncologists and Pathologists, and he is the founder of the Collaborative Ocular Oncology Group.
Education & Training
Professional Associations & Affiliations
- American Academy of Ophthalmology
- American Association for Cancer Research
- American Association of Ophthalmic Oncologists and Pathologists
- American Ophthalmological Society
- American Society of Retina Specialists
- Association of American Physicians
- Association for Research in Vision and Ophthalmology
- Children’s Oncology Group
- Collaborative Ocular Oncology Group (Founder)
- International Society of Ocular Oncology
- J. Donald M. Gass Society
- Macula Society
- Retina Society
- Society of Heed Fellows
- Society for Melanoma Research
Honors & Awards
- Alcon Research Institute Award 2016
- Retina Research Foundation/Kayser Global Award 2015, Pan-American Association of Ophthalmology
- Silver Fellow 2014, Association for Research in Vision and Ophthalmology
- Senior Scientific Investigator 2014, Research to Prevent Blindness, Inc.
- Paul Henkind Memorial Award and Lecture 2014, Macula Society
- Honor Award 2013, American Society of Retina Specialists
- Shaler Richardson, MD Service to Medicine Award 2013, Florida Society of Ophthalmology
- Senior Achievement Award 2012, American Academy of Ophthalmology
- Research Award 2011, Ocular Melanoma Foundation
- Rosenthal Award 2008, Macula Society
- Cogan Award 2005, Association for Research in Vision and Ophthalmology
- Achievement Award 2003, American Academy of Ophthalmology
- Physician-Scientist Award 2002, Research to Prevent Blindness, Inc.
- Heed-Knapp Ophthalmic Fellowship 1995-1996, University of California, San Francisco
- Heed Ophthalmic Foundation Fellowship 1994-1995, Bascom Palmer Eye Institute
Books & Publications
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Publications
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15-Gene Expression Profile and PRAME as Integrated Prognostic Test for Uveal Melanoma: First Report of Collaborative Ocular Oncology Group Study No. 2 (COOG2.1)
Harbour JW, Correa ZM, Schefler AC, Mruthyunjaya P, Materin MA, Aaberg TA, Skalet AH, Reichstein DA, Weis E, Kim IK, Fuller TS, Demirci H, Piggott KD, Williams BK, Shildkrot E, Capone A, Oliver SC, Walter SD, Mason J, Char DH, Altaweel M, Wells JR, Duker JS, Hovland PG, Gombos DS, Tsai T, Javid C, Marr BP, Gao A, Decatur CL, Dollar JJ, Kurtenbach S, Zhang S Journal of Clinical Oncology 2024 Oct 42 3319-3329 -
Do Short Delays in Treatment Affect Uveal Melanoma Prognosis?
Harbour JW, Correa ZM, Stacey AW Ophthalmology 2024 Sep 131 1105-1106 -
BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system
Schneider S, Anderson JB, Bradley RP, Beigel K, Wright CM, Maguire BA, Yan G, Taylor DM, Harbour JW, Heuckeroth RO Journal of Clinical Investigation 2024 May 134 -
PRAME induces genomic instability in uveal melanoma
Kurtenbach S, Sanchez MI, Kuznetsoff J, Rodriguez DA, Weich N, Dollar JJ, Cruz A, Kurtenbach S, Field MG, Durante MA, Decatur C, Sorouri M, Lai F, Yenisehirli G, Fang B, Shiekhattar R, Pelaez D, Correa ZM, Verdun RE, Harbour JW Oncogene 2024 Feb 43 555-565 -
Vitreous metastasis from cutaneous melanoma: diagnosis and management
Ashkenazy N, Harbour JW, Dubovy SR, Albini TA, Sridhar J, Patel N, Hansen ED, Uchiyama E, Rubsamen PE, Correa ZM Arquivos Brasileiros de Oftalmologia 2024 87 -
Correction: Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis (Oncogene, (2023), 42, 35, (2629-2640), 10.1038/s41388-023-02792-6)
Richards JR, Shin D, Pryor R, Sorensen LK, Sun Z, So WM, Park G, Wolff R, Truong A, McMahon M, Grossmann AH, Harbour JW, Zhu W, Odelberg SJ, Yoo JH Oncogene 2023 Sep 42 3015 -
Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis
Richards JR, Shin D, Pryor R, Sorensen LK, Sun Z, So WM, Park G, Wolff R, Truong A, McMahon M, Grossmann AH, Harbour JW, Zhu W, Odelberg SJ, Yoo JH Oncogene 2023 Aug 42 2629-2640 -
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth
Han A, Mukha D, Chua V, Purwin TJ, Tiago M, Modasia B, Baqai U, Aumiller JL, Bechtel N, Hunter E, Danielson M, Terai M, Wedegaertner PB, Sato T, Landreville S, Davies MA, Kurtenbach S, Harbour JW, Schug ZT, Aplin AE Cancers 2023 Jul 15 -
IRIS METASTASIS from BREAST CANCER SUCCESSFULLY TREATED with ABEMACICLIB and LETROZOLE
Goduni L, Ashkenazy N, Hansen E, Soyano-Muller A, Correa ZM, Harbour JW Retinal Cases and Brief Reports 2023 Mar 17 123-125 -
Advances in the clinical management of uveal melanoma
Carvajal RD, Sacco JJ, Jager MJ, Eschelman DJ, Olofsson Bagge R, Harbour JW, Chieng ND, Patel SP, Joshua AM, Piperno-Neumann S Nature Reviews Clinical Oncology 2023 Feb 20 99-115 -
Post-Radiation Cataract Management: Outcomes in Individuals with Uveal Melanoma
Sepulveda-Beltran PA, Levine H, Gibbons AG, Maharaj A, Choi DS, Martinez JD, Correa ZM, Amescua G, Harbour JW Current Ophthalmology Reports 2022 Dec 10 218-227 -
HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma
Sriramareddy SN, Faião-Flores F, Emmons MF, Saha B, Chellappan S, Wyatt C, Smalley I, Licht JD, Durante MA, Harbour JW, Smalley KS Cancer Gene Therapy 2022 Dec 29 1840-1846 -
Predictors of Local Recurrence and Progression-Free Survival in Iodine-125 Brachytherapy-Treated Uveal Melanomas: A Modern Institutional Study
Gurayah AA, Peters VA, Jin W, Kalahasty K, Kwon D, Zhao W, Patel NV, Markoe AM, Correa ZM, Studenski MT, Harbour JW, Samuels SE Ocular Oncology and Pathology 2022 Nov 8 175-180 -
Clinical characteristics and postoperative complications as predictors of radiation toxicity after treatment with I125 Eye Plaque Brachytherapy for Uveal Melanomas
Peters V, Gurayah A, Jin W, Kwon D, Zhao W, Patel NV, Markoe A, Correa Z, Studenski MT, Harbour JW, Samuels SE Brachytherapy 2022 Nov 21 896-903 -
Early Mechanisms of Chemoresistance in Retinoblastoma
Zhang MG, Kuznetsoff JN, Owens DA, Gallo RA, Kalahasty K, Cruz AM, Kurtenbach S, Correa ZM, Pelaez D, Harbour JW Cancers 2022 Oct 14 -
Translational Epidemiology: An Integrative Approach to Determine the Interplay between Genetic Ancestry and Neighborhood Socioeconomic Status on Triple Negative Breast Cancer
Goel N, Yadegarynia S, Kwon D, Kesmodel SB, Harbour JW, Kobetz E, Merchant N, Rodriguez DA Annals of surgery 2022 Sep 276 430-440 -
DIAGNOSING EXOPHYTIC RETINAL CAPILLARY HEMANGIOBLASTOMA
Russell JF, Villegas VM, Rosenfeld PJ, Harbour JW Retina Today 2022 Sep 2022 21-61 -
Pseudoangiomatous retinal gliosis (PARG) treated with iodine plaque in patient with chronic retinal detachment
Marquez MA, Fortun J, Iyer P, Harbour JW, Haddock LJ American Journal of Ophthalmology Case Reports 2022 Sep 27 -
Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma
Baqai U, Purwin TJ, Bechtel N, Chua V, Han A, Hartsough EJ, Kuznetsoff JN, Harbour JW, Aplin AE Molecular Cancer Research 2022 Aug 20 1260-1271 -
Adjuvant crizotinib in high-risk uveal melanoma following definitive therapy
Khan S, Lutzky J, Shoushtari AN, Jeter J, Marr B, Olencki TE, Cebulla CM, Abdel-Rahman M, Harbour JW, Sender N, Nesson A, Singh-Kandah S, Hernandez S, King J, Katari MS, Dimapanat L, Izard S, Ambrosini G, Surriga O, Rai AJ, Chiuzan C, Schwartz GK, Carvajal RD Frontiers in Oncology 2022 Aug 12 -
BAP1 Loss Promotes Suppressive Tumor Immune Microenvironment via Upregulation of PROS1 in Class 2 Uveal Melanomas
Kaler CJ, Dollar JJ, Cruz AM, Kuznetsoff JN, Sanchez MI, Decatur CL, Licht JD, Smalley KS, Correa ZM, Kurtenbach S, Harbour JW Cancers 2022 Aug 14 -
RB1 loss triggers dependence on ESRRG in retinoblastoma
Field MG, Kuznetsoff JN, Zhang MG, Dollar JJ, Durante MA, Sayegh Y, Decatur CL, Kurtenbach S, Pelaez D, Harbour JW Science Advances 2022 Aug 8 -
The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries
Author Collaboration TG, Fabian ID, Abdallah E, Abdullahi SU, Abdulqader RA, Abdulrahaman AA, Abouelnaga S, Ademola-Popoola DS, Adio A, Afifi MA, Afshar AR, Aggarwal P, Aghaji AE, Ahmad A, Akib MN, Akinsete A, Al Harby L, Al Mesfer S, Al Ani MH, Alarcón Portabella S, Al-Badri SA, Alcasabas AP, Al-Dahmash SA, Alejos A, Alemany-Rubio E, Alfa Bio AI, Alfonso Carreras Y, Al-Haddad CE, Al-Hussaini HH, Ali AM, Alia DB, Al-Jadiry MF, Al-Jumaily U, Alkatan HM, All-Eriksson C, Al-Mafrachi AA, Almeida AA, Alsawidi KM, Al-Shaheen AA, Al-Shammary EH, Amankwaa-Frempong D, Amiruddin PO, Armytasari I, Astbury NJ, Atalay HT, Ataseven E, Atchaneeyasakul Lo, Atsiaya R, Autrata R, Balaguer J, Harbour JW The Lancet Global Health 2022 Aug 10 e1128-e1140 -
Hematologic Complications Associated with Intra-arterial Chemotherapy for Retinoblastoma Treatment: A Single Institution Experience
Sanati-Mehrizy A, Ghosh T, Peterson E, Starke RM, Harbour JW, Corrales-Medina FF Journal of Pediatric Hematology/Oncology 2022 May 44 181-185 -
Gain of Chromosome 6p Correlates with Severe Anaplasia, Cellular Hyperchromasia, and Extraocular Spread of Retinoblastoma
Stålhammar G, Yeung A, Mendoza P, Dubovy SR, William Harbour J, Grossniklaus HE Ophthalmology Science 2022 Mar 2 -
Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma
Han A, Chua V, Baqai U, Purwin TJ, Bechtel N, Hunter E, Tiago M, Seifert E, Speicher DW, Schug ZT, Harbour JW, Aplin AE Oncogene 2022 Feb 41 1129-1139 -
Multiple genetically distinct uveal melanomas arise in the same eye of two patients with melanosis oculi
Wagley S, Belin PJ, Dollar JJ, Harbour JW, Maltry AC, Mruthyunjaya P, Schefler AC, Tang PH American journal of ophthalmology 2022 Feb 234 1-5 -
The AMP-dependent kinase pathway is upregulated in BAP1 mutant uveal melanoma
Chua V, Han A, Bechtel N, Purwin TJ, Hunter E, Liao C, Harbour JW, Aplin AE Pigment Cell and Melanoma Research 2022 Jan 35 78-87 -
Intraocular Lymphoma
Echegaray JJ, Harbour JW 2022 Jan 7783-7793 -
Functional impact of titin (TTN) mutations in ocular surface squamous neoplasia
Djulbegovic MB, Uversky VN, Karp CL, Harbour JW International Journal of Biological Macromolecules 2022 Jan 195 93-101 -
Secondary Glaucoma Associated with Intraocular Metastatic Cutaneous Melanoma
Greenfield JA, Rowlands M, Harbour JW Ophthalmology Glaucoma 2022 Jan 5 119-120 -
Choroidal Nevus and Melanocytoma
Alhumaid S, Harbour JW 2022 Jan 7795-7805 -
Waking up with Cloudy Vision
Khine KT, Clark WM, Harbour JW JAMA Ophthalmology 2021 Dec 139 1321-1322 -
Uphyloplot2: visualizing phylogenetic trees from single-cell RNA-seq data
Kurtenbach S, Cruz AM, Rodriguez DA, Durante MA, Harbour JW BMC Genomics 2021 Dec 22 -
Multiregional genetic evolution of metastatic uveal melanoma
Rodriguez DA, Yang J, Durante MA, Shoushtari AN, Moschos SJ, Wrzeszczynski KO, Harbour JW, Carvajal RD npj Genomic Medicine 2021 Dec 6 -
Analytical Validation and Performance of a 7-Gene Next-Generation Sequencing Panel in Uveal Melanoma
Alsina KM, Sholl LM, Covington KR, Arnal SM, Durante MA, Decatur CL, Stone JF, Oelschlager KM, Harbour JW, Monzon FA, Cook RW, Borman S Ocular Oncology and Pathology 2021 Dec 7 428-436 -
Comprehensive assessment of the effect of eye plaque tilt on tumor dosimetry
Studenski MT, Markoe A, Samuels SE, Correa ZM, Bossart E, Harbour JW Brachytherapy 2021 Nov 20 1289-1295 -
Structural protein analysis of driver gene mutations in conjunctival melanoma
Djulbegovic MB, Uversky VN, Harbour JW, Galor A, Karp CL Genes 2021 Oct 12 -
Iris Mass in a 14-Month-Old Boy
Ashkenazy N, Walter SD, Harbour JW JAMA Ophthalmology 2021 Jul 139 802-803 -
Kinetic characterization of ASXL1/2-mediated allosteric regulation of the BAP1 deubiquitinase
Peng H, Cassel J, McCracken DS, Prokop JW, Sementino E, Cheung M, Collop PR, Polo A, Joshi S, Mandell JP, Ayyanathan K, Hinds D, Malkowicz SB, Harbour JW, Bowcock AM, Salvino J, Kennedy EJ, Testa JR, Rauscher FJ Molecular Cancer Research 2021 Jul 19 1099-1112 -
Therapeutic escape in gaq-mutant uveal melanoma: It's a FAK
Harbour JW Clinical Cancer Research 2021 Jun 27 2967-2969 -
Multimodal Imaging in the Diagnosis of Exophytic Juxtapapillary Retinal Capillary Hemangioblastoma
Russell JF, Villegas VM, Schwartz SG, Weng CY, Davis JL, Flynn HW, Harbour JW American journal of ophthalmology 2021 May 225 128-136 -
PieParty: visualizing cells from scRNA-seq data as pie charts
Kurtenbach S, Dollar JJ, Cruz AM, Durante MA, Decatur CL, Harbour JW Life Science Alliance 2021 May 4 -
Correction to: BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors (Oncogene, (2021), 40, 3, (618-632), 10.1038/s41388-020-01554-y)
Han A, Purwin TJ, Bechtel N, Liao C, Chua V, Seifert E, Sato T, Schug ZT, Speicher DW, Harbour JW, Aplin AE Oncogene 2021 Mar 40 1753 -
Dual screen for efficacy and toxicity identifies HDAC inhibitor with distinctive activity spectrum for BAP1-mutant uveal melanoma
Kuznetsoff JN, Owens DA, Lopez A, Rodriguez DA, Chee NT, Kurtenbach S, Bilbao D, Roberts ER, Volmar CH, Wahlestedt C, Brothers SP, Harbour JW Molecular Cancer Research 2021 Feb 19 215-222 -
RETINOCYTOMA WITH VITREOUS SEEDING: NEW INSIGHTS FROM ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY AND HIGH-RESOLUTION POSTERIOR SEGMENT ULTRASONOGRAPHY
Garoon RB, Medina CA, Scelfo C, Harbour JW Retinal Cases and Brief Reports 2021 15 68-70 -
Chimerism involving a RB1 pathogenic variant in monochorionic dizygotic twins with twin–twin transfusion syndrome
Armitage AM, Kundra MA, Ghiam N, Atwal PS, Morel D, Hruska KS, Torene R, Harbour JW, Forghani I American Journal of Medical Genetics, Part A 2021 Jan 185 208-212 -
Molecular Basis of Uveal Melanoma and Emerging Therapeutic Targets
Harbour JW, Correa ZM 2021 Jan 3-12 -
BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors
Han A, Purwin TJ, Bechtel N, Liao C, Chua V, Seifert E, Sato T, Schug ZT, Speicher DW, William Harbour J, Aplin AE Oncogene 2021 Jan 40 618-632 -
Single-cell analysis reveals new evolutionary complexity in uveal melanoma
Durante MA, Rodriguez DA, Kurtenbach S, Kuznetsov JN, Sanchez MI, Decatur CL, Snyder H, Feun LG, Livingstone AS, Harbour JW Nature communications 2020 Dec 11 -
A novel cardiomyogenic role for Isl1+ neural crest cells in the inflow tract
Hatzistergos KE, Durante MA, Valasaki K, Wanschel AC, William Harbour J, Hare JM Science Advances 2020 Dec 6 -
Use of a modified plastic viewing system for safer general anesthesia care in pediatric ophthalmic surgery during the covid-19 pandemic
Ashkenazy N, Orihuela G, Rodriguez LI, Negron CI, William Harbour J, Berrocal AM Ophthalmic Surgery Lasers and Imaging Retina 2020 Nov 51 651-652 -
Impact of genetic ancestry on prognostic biomarkers in uveal melanoma
Rodriguez DA, Sanchez MI, Decatur CL, Correa ZM, Martin ER, Harbour JW Cancers 2020 Nov 12 1-13 -
Bilateral uveitis associated with nivolumab therapy for metastatic non-small cell lung cancer
Dermarkarian CR, Patel NA, Villegas VM, Harbour JW American Journal of Ophthalmology Case Reports 2020 Jun 18 -
Decitabine limits escape from MEK inhibition in uveal melanoma
Gonçalves J, Emmons MF, Faião-Flores F, Aplin AE, Harbour JW, Licht JD, Wink MR, Smalley KS Pigment Cell and Melanoma Research 2020 May 33 507-514 -
Global Retinoblastoma Presentation and Analysis by National Income Level
Fabian ID, Abdallah E, Abdullahi SU, Abdulqader RA, Adamou Boubacar S, Ademola-Popoola DS, Adio A, Afshar AR, Aggarwal P, Aghaji AE, Ahmad A, Akib MN, Al Harby L, Al Ani MH, Alakbarova A, Portabella SA, Al-Badri SA, Alcasabas AP, Al-Dahmash SA, Alejos A, Alemany-Rubio E, Alfa Bio AI, Alfonso Carreras Y, Al-Haddad C, Al-Hussaini HH, Ali AM, Alia DB, Al-Jadiry MF, Al-Jumaly U, Alkatan HM, All-Eriksson C, Al-Mafrachi AA, Almeida AA, Alsawidi KM, Al-Shaheen AA, Al-Shammary EH, Amiruddin PO, Antonino R, Astbury NJ, Atalay HT, Atchaneeyasakul LO, Atsiaya R, Attaseth T, Aung TH, Ayala S, Baizakova B, Balaguer J, Balayeva R, Balwierz W, Barranco H, Bascaran C, Beck Popovic M, Benavides R, Benmiloud S, Bennani Guebessi N, Berete RC, Berry JL, Bhaduri A, Bhat S, Biddulph SJ, Biewald EM, Bobrova N, Boehme M, Boldt HC, Bonanomi MT, Bornfeld N, Bouda GC, Bouguila H, Boumedane A, Brennan RC, Brichard BG, Buaboonnam J, Calderón-Sotelo P, Calle Jara DA, Camuglia JE, Cano MR, Capra M, Cassoux N, Castela G, Castillo L, Català-Mora J, Chantada GL, Chaudhry S, Chaugule SS, Chauhan A, Chawla B, Chernodrinska VS, Chiwanga FS, Chuluunbat T, Cieslik K, Cockcroft RL, Comsa C, Correa ZM, Correa Llano MG, Corson TW, Cowan-Lyn KE, Csóka M, Cui X, Da Gama IV, Dangboon W, Das A, Das S, Davanzo JM, Davidson A, De Potter P, Delgado KQ, Demirci H, Desjardins L, Diaz Coronado RY, Dimaras H, Dodgshun AJ, Donaldson C, Donato Macedo CR, Dragomir MD, Du Y, Du Bruyn M, Edison KS, Eka Sutyawan IW, El Kettani A, Elbahi AM, Elder JE, Elgalaly D, Elhaddad AM, Elhassan MM, Elzembely MM, Essuman VA, Evina TG, Fadoo Z, Fandiño AC, Faranoush M, Fasina O, Fernández DD, Fernández-Teijeiro A, Foster A, Frenkel S, Fu LD, Fuentes-Alabi SL, Gallie BL, Gandiwa M, Garcia JL, García Aldana D, Gassant PY, Geel JA, Ghassemi F, Girón AV, Gizachew Z, Goenz MA, Gold AS, Goldberg-Lavid M, Gole GA, Gomel N, Gonzalez E, Gonzalez Perez G, González-Rodríguez L, Garcia Pacheco HN, Graells J, Green L, Gregersen PA, Grigorovski ND, Guedenon KM, Gunasekera DS, Gündüz AK, Gupta H, Gupta S, Hadjistilianou T, Hamel P, Hamid SA, Hamzah N, Hansen ED, Harbour JW, Hartnett ME, Hasanreisoglu M, Hassan S, Hassan S, Hederova S, Hernandez J, Hernandez LM, Hessissen L, Hordofa DF, Huang LC, Hubbard GB, Hummlen M, Husakova K, Hussein Al-Janabi AN, Ida R, Ilic VR, Jairaj V, Jeeva I, Jenkinson H, Ji X, Jo DH, Johnson KP, Johnson WJ, Jones MM, Kabesha TB, Kabore RL, Kaliki S, Kalinaki A, Kantar M, Kao LY, Kardava T, Kebudi R, Kepak T, Keren-Froim N, Khan ZJ, Khaqan HA, Khauv P, Kheir WJ, Khetan V, Khodabande A, Khotenashvili Z, Kim JW, Kim JH, Kiratli H, Kivelä TT, Klett A, Komba Palet JE, Krivaitiene D, Kruger M, Kulvichit K, Kuntorini MW, Kyara A, Lachmann ES, Lam CP, Lam GC, Larson SA, Latinović S, Laurenti KD, Le BH, Lecuona K, Leverant AA, Li C, Limbu B, Long QB, López JP, Lukamba RM, Lumbroso L, Luna-Fineman S, Lutfi D, Lysytsia L, Magrath GN, Mahajan A, Majeed AR, Maka E, Makan M, Makimbetov EK, Manda C, Martín Begue N, Mason L, Mason JO, Matende IO, Materin M, Mattosinho CC, Matua M, Mayet I, Mbumba FB, McKenzie JD, Medina-Sanson A, Mehrvar A, Mengesha AA, Menon V, Mercado GJ, Mets MB, Midena E, Mishra DK, Mndeme FG, Mohamedani AA, Mohammad MT, Moll AC, Montero MM, Morales RA, Moreira C, Mruthyunjaya P, Msina MS, Msukwa G, Mudaliar SS, Muma KI, Munier FL, Murgoi G, Murray TG, Musa KO, Mushtaq A, Mustak H, Muyen OM, Naidu G, Nair AG, Naumenko L, Ndoye Roth PA, Nency YM, Neroev V, Ngo H, Nieves RM, Nikitovic M, Nkanga ED, Nkumbe H, Nuruddin M, Nyaywa M, Obono-Obiang G, Oguego NC, Olechowski A, Oliver SC, Osei-Bonsu P, Ossandon D, Paez-Escamilla MA, Pagarra H, Painter SL, Paintsil V, Paiva L, Pal BP, Palanivelu MS, Papyan R, Parrozzani R, Parulekar M, Pascual Morales CR, Paton KE, Pawinska-Wasikowska K, Pe'Er J, Peña A, Perić S, Pham CT, Philbert R, Plager DA, Pochop P, Polania RA, Polyakov VG, Pompe MT, Pons JJ, Prat D, Prom V, Purwanto I, Qadir AO, Qayyum S, Qian J, Rahman A, Rahman S, Rahmat J, Rajkarnikar P, Ramanjulu R, Ramasubramanian A, Ramirez-Ortiz MA, Raobela L, Rashid R, Reddy MA, Reich E, Renner LA, Reynders D, Ribadu D, Riheia MM, Ritter-Sovinz P, Rojanaporn D, Romero L, Roy SR, Saab RH, Saakyan S, Sabhan AH, Sagoo MS, Said AM, Saiju R, Salas B, San Román Pacheco S, Sánchez GL, Sayalith P, Scanlan TA, Schefler AC, Schoeman J, Sedaghat A, Seregard S, Seth R, Shah AS, Shakoor SA, Sharma MK, Sherief ST, Shetye NG, Shields CL, Siddiqui SN, Sidi Cheikh S, Silva S, Singh AD, Singh N, Singh U, Singha P, Sitorus RS, Skalet AH, Soebagjo HD, Sorochynska T, Ssali G, Stacey AW, Staffieri SE, Stahl ED, Stathopoulos C, Stirn Kranjc B, Stones DK, Strahlendorf C, Suarez ME, Sultana S, Sun X, Sundy M, Superstein R, Supriyadi E, Surukrattanaskul S, Suzuki S, Svojgr K, Sylla F, Tamamyan G, Tan D, Tandili A, Tarrillo Leiva FF, Tashvighi M, Tateshi B, Tehuteru ES, Teixeira LF, Teh KH, Theophile T, Toledano H, Trang DL, Traoré F, Trichaiyaporn S, Tuncer S, Tyau-Tyau H, Umar AB, Unal E, Uner OE, Urbak SF, Ushakova TL, Usmanov RH, Valeina S, Van Hoefen Wijsard M, Varadisai A, Vasquez L, Vaughan LO, Veleva-Krasteva NV, Verma N, Victor AA, Viksnins M, Villacís Chafla EG, Vishnevskia-Dai V, Vora T, Wachtel AE, Wackernagel W, Waddell K, Wade PD, Wali AH, Wang YZ, Weiss A, Wilson MW, Wime AD, Wiwatwongwana A, Wiwatwongwana D, Wolley Dod C, Wongwai P, Xiang D, Xiao Y, Yam JC, Yang H, Yanga JM, Yaqub MA, Yarovaya VA, Yarovoy AA, Ye H, Yousef YA, Yuliawati P, Zapata López AM, Zein E, Zhang C, Zhang Y, Zhao J, Zheng X, Zhilyaeva K, Zia N, Ziko OA, Zondervan M, Bowman R JAMA Oncology 2020 May 6 685-695 -
Influence of tumor shape and location in eye plaque brachytherapy dosimetry
Studenski MT, Patel NV, Markoe A, Harbour JW, Samuels SE Brachytherapy 2020 Mar 19 249-254 -
Single-cell analysis of olfactory neurogenesis and differentiation in adult humans
Durante MA, Kurtenbach S, Sargi ZB, Harbour JW, Choi R, Kurtenbach S, Goss GM, Matsunami H, Goldstein BJ Nature neuroscience 2020 Mar 23 323-326 -
Multi-center analysis of intraocular biopsy technique and outcomes for uveal melanoma: Ocular Oncology Study Consortium report 4
Author Collaboration OO, Seider MI, Berry DE, Schefler AC, Materin M, Stinnett S, Mruthyunjaya P, Raufi NN, Harbour JW, Berry JL, Kim J, Skalet A, Miller A, Liu T, Demirci H, Ozkurt ZG, Hovland P, Aaberg T, Kim RS, Tann A Graefe's Archive for Clinical and Experimental Ophthalmology 2020 Feb 258 427-435 -
Biological mechanisms and clinical signifi cance of BAP1 mutations in human cancer
Carbone M, Harbour JW, Brugarolas J, Bononi A, Pagano I, Dey A, Krausz T, Pass HI, Yang H, Gaudino G Cancer discovery 2020 10 1103-1120 -
Vitreoretinal lymphoma followed by systemic diffuse large B cell lymphoma
Fan KC, Tran KD, Harbour JW, Dubovy SA, Patel NA, Albini TA Journal of Ophthalmic Inflammation and Infection 2019 Dec 9 -
Intraocular Metastasis in Unilateral Multifocal Uveal Melanoma Without Melanocytosis or Germline BAP1 Mutations
Durante MA, Walter SD, Paez-Escamilla M, Tokarev J, Decatur CL, Dubovy SR, Schefler AC, Harbour JW JAMA Ophthalmology 2019 Dec 137 1434-1439 -
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma
Faião-Flores F, Emmons MF, Durante MA, Kinose F, Saha B, Fang B, Koomen JM, Chellappan SP, Maria-Engler SS, Rix U, Licht JD, Harbour JW, Smalley KS Clinical Cancer Research 2019 Sep 25 5686-5701 -
BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers
Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA, Rodriguez DA, King ML, William Harbour J Science Advances 2019 Sep 5 -
BAP1 loss is associated with DNA methylomic repatterning in highly aggressive class 2 uveal melanomas
Field MG, Kuznetsov JN, Bussies PL, Cai LZ, Alawa KA, Decatur CL, Kurtenbach S, Harbour JW Clinical Cancer Research 2019 Sep 25 5663-5673 -
Integrative copy number analysis of uveal melanoma reveals novel candidate genes involved in tumorigenesis including a tumor suppressor role for PHF10/BAF45A
Anbunathan H, Verstraten R, Singh AD, William Harbour J, Bowcock AM Clinical Cancer Research 2019 Aug 25 5156-5166 -
Dosimetric comparison of circular Eye Physics and Collaborative Ocular Melanoma Study plaques to treat uveal melanoma
Dean MK, Studenski MT, Paez-Escamilla MA, Walter SD, Kwon D, Markoe AM, Harbour JW, Samuels SE Brachytherapy 2019 May 18 404-410 -
Bilateral radiation therapy followed by methotrexate-based chemotherapy for primary vitreoretinal lymphoma
de la Fuente MI, Alderuccio JP, Reis IM, Omuro A, Markoe A, Echegaray JJ, Davis JL, Harbour JW, Lossos IS American Journal of Hematology 2019 Apr 94 455-460 -
CD4+/CD8+ immunophenotype switching as a marker for intraocular and CNS involvement in mycosis fungoides
Husnain M, Mackrides N, Vega F, Paez-Escamilla M, Markoe AM, Harbour JW, Lossos IS Leukemia and Lymphoma 2019 Apr 60 1308-1311 -
Persistent fetal vasculature presenting with axial elongation and platyphakia
Lin J, Paez-Escamilla M, Teira LE, Fallas B, Harbour JW Journal of AAPOS 2019 Feb 23 51-53 -
An eight-year-old girl presents with two weeks of vision loss and nightly headaches
Scott NL, Tran KD, Cernichiaro-Espinosa LA, Russell JF, Hinkle JW, Harbour JW, Dubovy SR, Berrocal AM Ophthalmic Surgery Lasers and Imaging Retina 2019 50 314-317 -
Are Risk Factors for Growth of Choroidal Nevi Associated With Malignant Transformation? Assessment With a Validated Genomic Biomarker
Harbour JW, Paez-Escamilla M, Cai L, Walter SD, Augsburger JJ, Correa ZM American journal of ophthalmology 2019 Jan 197 168-179 -
Longitudinal examination of fellow-eye vascular anomalies in coats’ disease with widefield fluorescein angiography: A multicenter study
Jeng-Miller KW, Soomro T, Scott NL, Rao P, Marlow E, Chang EY, Ells A, Chau F, Nudleman E, Calvo CM, Patel N, Schwartz R, Cernichiaro-Espinosa LA, Montoya AG, Goldstein J, Harper CA, Baumal CR, Hartnett ME, Harbour JW, Besirli CG, Gupta MP, Chan RV, Drenser KA, Capone A, Murray TG, Mukai S, Trese MT, Berrocal AM, Wong SC, Yonekawa Y Ophthalmic Surgery Lasers and Imaging Retina 2019 50 221-227 -
Genomic evolution of uveal melanoma arising in ocular melanocytosis
Durante MA, Field MG, Sanchez MI, Covington KR, Decatur CL, Dubovy SR, Harbour JW Cold Spring Harbor Molecular Case Studies 2019 5 -
ChIPprimersDB: A public repository of verified qPCR primers for chromatin immunoprecipitation (ChIP)
Kurtenbach S, Reddy R, Harbour JW Nucleic acids research 2019 Jan 47 D46-D49 -
Follow the nevus: The cost-utility of monitoring for growth of choroidal nevi
Barsam AS, Gibbons A, McClellan AJ, Harbour JW, Smiddy WE International Journal of Ophthalmology 2019 12 1456-1464 -
Intraocular dissemination of uveal melanoma cells following radiotherapy: Evolving management over the past decade
Paez-Escamilla M, Walter SD, Mohsenin A, Decatur CL, Harocopos GJ, Dubovy S, Harbour JW Ophthalmic Surgery Lasers and Imaging Retina 2019 50 573-579 -
Drug and disease signature integration identifies synergistic combinations in glioblastoma
Stathias V, Jermakowicz AM, Maloof ME, Forlin M, Walters W, Suter RK, Durante MA, Williams SL, Harbour JW, Volmar CH, Lyons NJ, Wahlestedt C, Graham RM, Ivan ME, Komotar RJ, Sarkaria JN, Subramanian A, Golub TR, Schürer SC, Ayad NG Nature communications 2018 Dec 9 -
Comprehensive study of the clinical phenotype of germline BAP1 variant-carrying families worldwide
Walpole S, Pritchard AL, Cebulla CM, Pilarski R, Stautberg M, Davidorf FH, de la Fouchardière A, Cabaret O, Golmard L, Stoppa-Lyonnet D, Garfield E, Njauw CN, Cheung M, Turunen JA, Repo P, Järvinen RS, van Doorn R, Jager MJ, Luyten GP, Marinkovic M, Chau C, Potrony M, Höiom V, Helgadottir H, Pastorino L, Bruno W, Andreotti V, Dalmasso B, Ciccarese G, Queirolo P, Mastracci L, Wadt K, Kiilgaard JF, Speicher MR, van Poppelen N, Kilic E, Al-Jamal RT, Dianzani I, Betti M, Bergmann C, Santagata S, Dahiya S, Taibjee S, Burke J, Poplawski N, O’Shea SJ, Newton-Bishop J, Adlard J, Adams DJ, Lane AM, Kim I, Klebe S, Racher H, Harbour JW, Nickerson ML, Murali R, Palmer JM, Howlie M, Symmons J, Hamilton H, Warrier S, Glasson W, Johansson P, Robles-Espinoza CD, Ossio R, de Klein A, Puig S, Ghiorzo P, Nielsen M, Kivelä TT, Tsao H, Testa JR, Gerami P, Stern MH, Bressac-De Paillerets B, Abdel-Rahman MH, Hayward NK Journal of the National Cancer Institute 2018 Dec 110 -
Punctuated evolution of canonical genomic aberrations in uveal melanoma
Field MG, Durante MA, Anbunathan H, Cai LZ, Decatur CL, Bowcock AM, Kurtenbach S, Harbour JW Nature communications 2018 Dec 9 -
Gene Expression Profiling and PRAME Status Versus Tumor-Node-Metastasis Staging for Prognostication in Uveal Melanoma
Cai L, Paez-Escamilla M, Walter SD, Tarlan B, Decatur CL, Perez BM, Harbour JW American journal of ophthalmology 2018 Nov 195 154-160 -
Diagnosis of bilateral retinocytoma in an adolescent patient using multimodal imaging and genetic testing
Paez-Escamilla M, Walter SD, Ramaiya KJ, Harbour JW Ophthalmic Surgery Lasers and Imaging Retina 2018 Oct 49 812-814 -
Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo
Guo Y, Yang H, Chen S, Zhang P, Li R, Nimer SD, Harbour JW, Xu M, Yang FC Leukemia 2018 Aug 32 1834-1837 -
Anterior Chamber Chemotherapy in Retinoblastoma-Necessary But Not Sufficient for Aqueous Seeding Control-Reply
Harbour JW, Paez-Escamilla M JAMA Ophthalmology 2018 May 136 597 -
In reply
William Harbour J, Paez-Escamilla M JAMA Ophthalmology 2018 May 136 597 -
Congenital hypertrophy of the retinal pigment epithelium presenting with secondary choroidal neovascularization
Garoon RB, William Harbour J Ophthalmic Surgery Lasers and Imaging Retina 2018 Apr 49 276-277 -
Familial and somatic BAP1 mutations inactivate ASXL1/2-mediated allosteric regulation of BAP1 deubiquitinase by targeting multiple independent domains
Peng H, Prokop J, Karar J, Park K, Cao L, Harbour JW, Bowcock AM, Malkowicz SB, Cheung M, Testa JR, Rauscher FJ Cancer research 2018 Mar 78 1200-1213 -
Retinoblastoma with endophytic and exophytic features
Paez-Escamilla M, Bagheri N, Harbour JW JAMA Ophthalmology 2018 Jan 136 -
Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies
Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, Zhou Y, Nimer SD, William Harbour J, Wahlestedt C, Xu M, Yang FC Blood 2018 Jan 131 328-341 -
Molecular characteristics of conjunctival melanoma using whole-exome sequencing
Swaminathan SS, Field MG, Sant D, Wang G, Galor A, Dubovy SR, Harbour JW, Karp CL JAMA Ophthalmology 2017 Dec 135 1434-1437 -
Intracameral topotecan hydrochloride for anterior chamber seeding of retinoblastoma
Paez-Escamilla M, Bagheri N, Teira LE, Corrales-Medina FF, Harbour JW JAMA Ophthalmology 2017 Dec 135 1453-1455 -
Liquid biopsy in retinoblastoma
Harbour JW JAMA Ophthalmology 2017 Nov 135 1231 -
Letter to the editor: Comparison of alternative tumor size classifications for posterior uveal melanomas
Harbour JW, Paez-Escamilla M Investigative Ophthalmology and Visual Science 2017 Oct 58 5444 -
Association between Tumor Regression Rate and Gene Expression Profile after Iodine 125 Plaque Radiotherapy for Uveal Melanoma
Author Collaboration OO, Mruthyunjaya P, Seider MI, Stinnett S, Schefler A, Seider M, Raufi NN, Berry D, Stinnett S, Harbour JW, Berry J, Kim J, Skalet A, Miller A, Materin MA, Liu T, Demirci H, Ozkurt ZG, Hovland P, Aaberg T, Schefler A, Kim RS, Tann A Ophthalmology 2017 Oct 124 1532-1539 -
Multimodal imaging of astrocytic hamartomas associated with tuberous sclerosis
Schwartz SG, Harbour JW Ophthalmic Surgery Lasers and Imaging Retina 2017 Sep 48 756-758 -
Fluorescein angiography findings in diffuse retinoblastoma: two case reports with clinicopathologic correlation
Fernandez MP, Al-Holou SN, Fischer O, Murray T, Harbour JW, Dubovy SR, Berrocal AM Journal of AAPOS 2017 Aug 21 337-339.e2 -
Incorporating clinical, histological, and genetic parameters for choroidal melanoma prognostication: In reply
Harbour JW JAMA Ophthalmology 2017 Jul 135 819-820 -
An international survey of classification and treatment choices for group D retinoblastoma
Scelfo C, Francis JH, Khetan V, Jenkins T, Marr B, Abramson DH, Shields CL, Pe’er J, Munier F, Berry J, Harbour JW, Yarovoy A, Lucena E, Murray TG, Bhagia P, Paysse E, Tuncer S, Chantada GL, Moll AC, Ushakova T, Plager DA, Ziyovuddin I, Leal CA, Materin MA, Ji XD, Cursino JW, Polania R, Kiratli H, All-Ericsson C, Kebudi R, Honavar SG, Vishnevskia-Dai V, Epelman S, Daniels AB, Ling JD, Traore F, Ramirez-Ortiz MA International Journal of Ophthalmology 2017 Jun 10 961-967 -
PRAME as a potential target for immunotherapy in metastatic uveal melanoma
Gezgin G, Luk SJ, Cao J, Dogrusöz M, Van Der Steen DM, Hagedoorn RS, Krijgsman D, Van Der Velden PA, Field MG, Luyten GP, Szuhai K, Harbour JW, Jordanova ES, Heemskerk MH, Jager MJ JAMA Ophthalmology 2017 Jun 135 541-549 -
In reply
Harbour JW JAMA Ophthalmology 2017 Feb 135 175-176 -
Preclinical acute ocular safety study of combined intravitreal carboplatin and etoposide phosphate for retinoblastoma
Mohney BG, Elner VM, Smith AB, William Harbour J, Smith BD, Musch DC, Smith SJ Ophthalmic Surgery Lasers and Imaging Retina 2017 Feb 48 151-159 -
ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis
Li Z, Zhang P, Yan A, Guo Z, Ban Y, Li J, Chen S, Yang H, He Y, Li J, Guo Y, Zhang W, Hajiramezanali E, An H, Fajardo D, William Harbour J, Ruan Y, Nimer SD, Yu P, Chen X, Xu M, Yang FC Science Advances 2017 Jan 3 -
An iris tumor
Rao RC, Harbour JW JAMA Ophthalmology 2016 Sep 134 1063-1064 -
The state of melanoma: challenges and opportunities
Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, Atkins MB, Bosenberg MW, Dummer R, Gershenwald JE, Halpern AC, Herlyn D, Karakousis GC, Kirkwood JM, Krauthammer M, Lo RS, Long GV, McArthur G, Ribas A, Schuchter L, Sosman JA, Smalley KS, Steeg P, Thomas NE, Tsao H, Tueting T, Weeraratna A, Xu G, Lomax R, Martin A, Silverstein S, Turnham T, Ronai ZA Pigment Cell and Melanoma Research 2016 Jul 29 404-416 -
Driver mutations in uveal melanoma associations with gene expression profile and patient outcomes
Decatur CL, Ong E, Garg N, Anbunathan H, Bowcock AM, Field MG, Harbour JW JAMA Ophthalmology 2016 Jul 134 728-733 -
Prognostic implications of tumor diameter in association with gene expression profile for uveal melanoma
Walter SD, Chao DL, Feuer W, Schiffman J, Char DH, Harbour JW JAMA Ophthalmology 2016 Jul 134 734-740 -
ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma
Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong ZZ, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY Cancer Cell 2016 Jun 29 889-904 -
PRAME as an independent biomarker for metastasis in uveal melanoma
Field MG, Decatur CL, Kurtenbach S, Gezgin G, Van Der Velden PA, Jager MJ, Kozak KN, Harbour JW Clinical Cancer Research 2016 Mar 22 1234-1242 -
Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and Class 2 uveal melanomas
Field MG, Durante MA, Decatur CL, Tarlan B, Oelschlager KM, Stone JF, Kuznetsov J, Bowcock AM, Kurtenbach S, Harbour JW Oncotarget 2016 7 59209-59219 -
A rare case of leptomeningeal carcinomatosis in a patient with uveal melanoma: Case report and review of literature
Fedorenko IV, Evernden B, Kenchappa RS, Sahebjam S, Ryzhova E, Puskas J, McIntosh L, Caceres G, Magliocco A, Etame A, Harbour JW, Smalley KS, Forsyth PA Melanoma research 2016 26 481-486 -
Uveal and Conjunctival Melanoma: Close Together-but Only Distantly Related
Harbour JW Oncology (Williston Park, N.Y.) 2016 Jan 30 44, 48 -
Retinoblastoma: Clinical and molecular perspectives
William Harbour J 2016 Jan 355-361 -
EMT-associated factors promote invasive properties of uveal melanoma cells
Asnaghi L, Gezgin G, Tripathy A, Handa JT, Merbs SL, van der Velden PA, Jager MJ, Harbour JW, Eberhart CG Molecular Vision 2015 Aug 21 919-929 -
Spectral-domain optical coherence tomography of presumed solitary circumscribed retinal astrocytic proliferation versus astrocytic hamartoma
Schwartz SG, Harbour JW Ophthalmic Surgery Lasers and Imaging Retina 2015 May 46 586-588 -
Serous macular detachment following a systemic corticosteroid injection
Weng CY, William Harbour J JAMA Ophthalmology 2015 Apr 133 473-474 -
Hydroxyapatite versus polyethylene orbital implants for patients undergoing enucleation for uveal melanoma
Chao DL, Harbour JW Canadian Journal of Ophthalmology 2015 Apr 50 151-154 -
Gene expression profiling and regression rate of irradiated uveal melanomas
Rao RC, Khan M, Badiyan SN, Harbour JW Ophthalmic Surgery Lasers and Imaging Retina 2015 Mar 46 333-337 -
Skewed expression of the genes encoding epigenetic modifiers in high-risk uveal melanoma
Herlihy N, Dogrusöz M, Van Essen TH, William Harbour J, Van Der Velden PA, Van Eggermond MC, Haasnoot GW, Van Den Elsen PJ, Jager MJ Investigative Ophthalmology and Visual Science 2015 56 1447-1458 -
Retinoblastoma Tumorigenesis
Dyer MA, Dyer MA, Harbour JW, Harbour JW, Harbour JW 2015 Jan 61-68 -
Second primary tumors in retinoblastoma
Harbour JW, Mohsenin A 2015 Jan 37-41 -
Molecular Biology of Retinoblastoma
Walter SD, William Harbour J Clinical and Translational Oncology 2015 10 1-13 -
Epigenetic reprogramming of melanoma cells by vitamin C treatment
Gustafson CB, Yang C, Dickson KM, Shao H, Van Booven D, Harbour JW, Liu ZJ, Wang G Clinical Epigenetics 2015 7 -
Prognostic parameters in uveal melanoma and their association with bap1 expression
Van Essen TH, Van Pelt S, Versluis M, Bronkhorst IH, Van Duinen SG, Marinkovic M, Kroes WG, Ruivenkamp CA, Shukla S, De Klein A, Kiliç E, Harbour JW, Luyten GP, Van Der Velden PA, Verdijk RM, Jager MJ British Journal of Ophthalmology 2014 Dec 98 1738-1743 -
Rapid regression of a subset of class 1 uveal melanomas after Iodine-125 plaque radiotherapy suggests an inflammatory mechanism
Chen RW, Harbour JW Graefe's Archive for Clinical and Experimental Ophthalmology 2014 Dec 252 2021-2022 -
Combined PKC and MEK inhibition for treating metastatic uveal melanoma
Sagoo MS, Harbour JW, Stebbing J, Bowcock AM Oncogene 2014 Sep 33 4722-4723 -
GNAQ/11 mutations in uveal melanoma: Is YAP the key to targeted therapy?
Field MG, Harbour JW Cancer Cell 2014 Jun 25 714-715 -
A molecular revolution in uveal melanoma: Implications for patient care and targeted therapy
William Harbour J, Chao DL Ophthalmology 2014 Jun 121 1281-1288 -
Recent developments in prognostic and predictive testing in uveal melanoma
Field MG, Harbour JW Current Opinion in Ophthalmology 2014 May 25 234-239 -
Outcomes of iodine-125 plaque brachytherapy for uveal melanoma with intraoperative ultrasonography and supplemental transpupillary thermotherapy
Badiyan SN, Rao RC, Apicelli AJ, Acharya S, Verma V, Garsa AA, Dewees T, Speirs CK, Garcia-Ramirez J, Esthappan J, Grigsby PW, Harbour JW International Journal of Radiation Oncology Biology Physics 2014 Mar 88 801-805 -
Distinguishing torpedo maculopathy from similar lesions of the posterior segment
Villegas VM, Schwartz SG, Flynn HW, Capó H, Berrocal AM, Murray TG, Harbour JW Ophthalmic Surgery Lasers and Imaging Retina 2014 45 222-226 -
A prognostic test to predict the risk of metastasis in uveal melanoma based on a 15-gene expression profile
Harbour JW 2014 427-440 -
Cancer genetics
William Harbour J, Chao DL 2014 Jan 63-68 -
Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-Obstruction
Fu M, Landreville S, Agapova OA, Wiley LA, Shoykhet M, Harbour JW, Heuckeroth RO Journal of Clinical Investigation 2013 Dec 123 5152-5164 -
BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma
Matatall KA, Agapova OA, Onken MD, Worley LA, Bowcock AM, Harbour JW BMC Cancer 2013 Aug 13 -
Erratum: Gene expression profiling versus TNM classification (Ophthalmology (2013) 120 (1109))
Harbour JW, Augsburger JJ, Char DH Ophthalmology 2013 Jul 120 e52-e53 -
Author reply
Harbour JW, Augsburger JJ, Char DH Ophthalmology 2013 Jul 120 e51 -
Patient-derived xenografts recapitulate molecular features of human uveal melanomas
Laurent C, Gentien D, Piperno-Neumann S, Némati F, Nicolas A, Tesson B, Desjardins L, Mariani P, Rapinat A, Sastre-Garau X, Couturier J, Hupé P, de Koning L, Dubois T, Roman-Roman S, Stern MH, Barillot E, Harbour JW, Saule S, Decaudin D Molecular oncology 2013 Jun 7 625-636 -
Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration
Sene A, Khan AA, Cox D, Nakamura RE, Santeford A, Kim BM, Sidhu R, Onken MD, Harbour JW, Hagbi-Levi S, Chowers I, Edwards PA, Baldan A, Parks JS, Ory DS, Apte RS Cell Metabolism 2013 Apr 17 549-561 -
The DecisionDx-UM Gene Expression Profile Test Provides Risk Stratification and Individualized Patient Care in Uveal Melanoma
Harbour JW, Chen R PLoS Currents 2013 Apr -
Molecular testing prognostic of low risk in epithelioid uveal melanoma in a child
Dimaras H, Parulekar MV, Kwok G, Simpson ER, Ali A, Halliday W, Shago M, Harbour JW, Héon E, Gallie BL, Chan HS British Journal of Ophthalmology 2013 Mar 97 323-326 -
Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma
Harbour JW, Roberson ED, Anbunathan H, Onken MD, Worley LA, Bowcock AM Nature genetics 2013 Feb 45 133-135 -
Gene expressing profiling of iris melanomas
Harbour JW, Wilson D, Finger PT, Worley LA, Onken MD Ophthalmology 2013 Jan 120 213-213.e3 -
Genomic, prognostic, and cell-signaling advances in uveal melanoma
Harbour JW American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting 2013 388-391 -
Multimodal imaging of sarcoid choroidal granulomas
Modi YS, Epstein A, Bhaleeya S, Harbour JW, Albini T Journal of Ophthalmic Inflammation and Infection 2013 3 1-4 -
A role for Jag2 in promoting uveal melanoma dissemination and growth
Asnaghi L, Handa JT, Merbs SL, Harbour JW, Eberhart CG Investigative Ophthalmology and Visual Science 2013 Jan 54 295-306 -
High throughput mass spectrometry-based mutation profiling of primary uveal melanoma
Daniels AB, Lee JE, MacConaill LE, Palescandolo E, Van Hummelen P, Adams SM, DeAngelis MM, Hahn WC, Gragoudas ES, William Harbour J, Garraway LA, Kim IK Investigative Ophthalmology and Visual Science 2012 Oct 53 6991-6996 -
Collaborative ocular oncology group report number 1: Prospective validation of a multi-gene prognostic assay in uveal melanoma
Onken MD, Worley LA, Char DH, Augsburger JJ, Correa ZM, Nudleman E, Aaberg TM, Altaweel MM, Bardenstein DS, Finger PT, Gallie BL, Harocopos GJ, Hovland PG, McGowan HD, Milman T, Mruthyunjaya P, Simpson ER, Smith ME, Wilson DJ, Wirostko WJ, Harbour JW Ophthalmology 2012 Aug 119 1596-1603 -
Uveal melanoma: Molecular pattern, clinical features, and radiation response
Chappell MC, Char DH, Cole TB, Harbour JW, Mishra K, Weinberg VK, Phillips TL American journal of ophthalmology 2012 Aug 154 227-332.e2 -
Update in uveal melanoma
William Harbour J Clinical Advances in Hematology and Oncology 2012 Jul 10 459-461 -
The genetics of uveal melanoma: An emerging framework for targeted therapy
Harbour JW Pigment Cell and Melanoma Research 2012 Mar 25 171-181 -
Notch signaling promotes growth and invasion in uveal melanoma
Asnaghi L, Ebrahimi KB, Schreck KC, Bar EE, Coonfield ML, Bell WR, Handa J, Merbs SL, Harbour JW, Eberhart CG Clinical Cancer Research 2012 Feb 18 654-665 -
Retinoblastoma
Lee TC, Gombos DS, William Harbour J, Mansfield NC, Linn Murphree A 2012 Jan 2104-2149 -
Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma
Landreville S, Agapova OA, Matatall KA, Kneass ZT, Onken MD, Lee RS, Bowcock AM, Harbour JW Clinical Cancer Research 2012 Jan 18 408-416 -
A new mutation with staggering effects
Harbour JW Pigment Cell and Melanoma Research 2011 Dec 24 1081-1082 -
ABCB1 identifies a subpopulation of uveal melanoma cells with high metastatic propensity
Landreville S, Agapova OA, Kneass ZT, Salesse C, William Harbour J Pigment Cell and Melanoma Research 2011 Jun 24 430-437 -
Diagnostic testing and treatment choices in primary vitreoretinal lymphoma
Rajagopal R, Harbour JW Retina 2011 Mar 31 435-440 -
P38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis
Delston RB, Matatall KA, Sun Y, Onken MD, Harbour JW Oncogene 2011 Feb 30 588-599 -
Primary vitreoretinal lymphoma: A report from an international primary central nervous system Lymphoma Collaborative group symposium
Chan CC, Rubenstein JL, Coupland SE, Davis JL, Harbour JW, Johnston PB, Cassoux N, Touitou V, Smith JR, Batchelor TT, Pulido JS Oncologist 2011 16 1589-1599 -
Frequent mutation of BAP1 in metastasizing uveal melanomas
Harbour JW, Onken MD, Roberson ED, Duan S, Cao L, Worley LA, Council ML, Matatall KA, Helms C, Bowcock AM Science 2010 Dec 330 1410-1413 -
Genomic research in uveal melanoma: Recent genetic discoveries have provided clues about how to improve prognostic testing of the disease
William Harbour J Retina Today 2010 Nov 67-69 -
Association between gene expression profile, proliferation and metastasis in uveal melanoma
Onken MD, Worley LA, Harbour JW Current Eye Research 2010 Sep 35 857-863 -
Review of 676 second primary tumors in patients with retinoblastoma: Association between age at onset and tumor type
Woo KI, Harbour JW Archives of Ophthalmology 2010 Jul 128 865-870 -
An accurate, clinically feasible multi-gene expression assay for predicting metastasis in uveal melanoma
Onken MD, Worley LA, Tuscan MD, Harbour JW Journal of Molecular Diagnostics 2010 Jul 12 461-468 -
Loss of Id2 potentiates the tumorigenic effect of Rb inactivation in a mouse model of retinoblastoma
Landreville S, Ma D, Wu J, Harbour JW Current Eye Research 2010 May 35 435-439 -
Molecular basis of low-penetrance retinoblastoma
Matatall K, Harbour JW 2010 Mar 377-382 -
A transformation in ocular oncology: From megacenter to multicenter
Harbour JW Archives of Ophthalmology 2010 Mar 128 367-368 -
Id2 deficiency promotes metastasis in a mouse model of ocular cancer
Agapova OA, Person E, Harbour JW Clinical and Experimental Metastasis 2010 Feb 27 91-96 -
Retina Congress 2009: Ocular oncology
Corrêa Zm, Harbour jW Expert Review of Ophthalmology 2010 Feb 5 13-14 -
Uveal melanoma
Corrêa ZM, Harbour JW 2010 362-368 -
Molecular basis of low-penetrance retinoblastoma
Matatall K, Harbour JW 2010 377-382 -
Molecular Prognostic Testing and Individualized Patient Care in Uveal Melanoma
Harbour JW American journal of ophthalmology 2009 Dec 148 823-829.e1 -
Pearls for imaging and diagnosis in ocular oncology: The use of new imaging modalities can help clinicians better understand the pathophysiology of intraocular tumors
Harbour JW, Corrêa ZM Retina Today 2009 Jul 61-65 -
Hepatic metastasis from uveal melanoma: Angiographic pattern predictive of survival after hepatic arterial chemoembolization
Dayani PN, Gould JE, Brown DB, Sharma KV, Linette GP, Harbour JW Archives of Ophthalmology 2009 May 127 628-632 -
Comment on "Low-penetrant RB allele in small-cell cancer shows geldanamycin instability and discordant expression with mutant ras" by Park et al.
Harbour JW Cell Cycle 2008 Aug 7 2276-2277 -
Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling
Worley LA, Long MD, Onken MD, Harbour JW Melanoma research 2008 Jun 18 184-190 -
Prognostic biomarkers in uveal melanoma: Evidence for a stem cell-like phenotype associated with metastasis
Chang SH, Worley LA, Onken MD, Harbour JW Melanoma research 2008 Jun 18 191-200 -
A metastasis modifier locus on human chromosome 8p in uveal melanoma identified by integrative genomic analysis
Onken MD, Worley LA, Harbour JW Clinical Cancer Research 2008 Jun 14 3737-3745 -
Oncogenic mutations in GNAQ occur early in uveal melanoma
Onken MD, Worley LA, Long MD, Duan S, Council ML, Bowcock AM, Harbour JW Investigative Ophthalmology and Visual Science 2008 49 5230-5234 -
Integrative genomic analysis of aneuploidy in uveal melanoma
Ehlers JP, Worley L, Onken MD, Harbour JW Clinical Cancer Research 2008 Jan 14 115-122 -
Correlation study of benign cytomorphology and final clinical diagnosis
Zhai J, Harbour JW, Smith ME, Dávila RM Acta Cytologica 2008 52 196-200 -
Tilting of radioactive plaques after initial accurate placement for treatment of uveal melanoma
Almony A, Breit S, Zhao H, Garcia-Ramirez J, Mansur DB, Harbour JW Archives of Ophthalmology 2008 Jan 126 65-70 -
Hepatic arterial chemoembolization for management of metastatic melanoma
Sharma KV, Gould JE, Harbour JW, Linette GP, Pilgram TK, Dayani PN, Brown DB American Journal of Roentgenology 2008 Jan 190 99-104 -
Current management of uveal melanoma
Ramaiya KJ, Harbour jW Expert Review of Ophthalmology 2007 Dec 2 939-946 -
Treatment outcomes for primary intraocular lymphoma: Implications for external beam radiotherapy
Berenbom A, Davila RM, Lin HS, Harbour JW Eye 2007 Sep 21 1198-1201 -
Molecular prognostic testing in uveal melanoma: Has it finally come of age?
Harbour JW Archives of Ophthalmology 2007 Aug 125 1122-1123 -
Inhibiting angiogenesis in retinoblastoma
Apte RS, Harbour JW Ophthalmic Research 2007 Aug 39 188-190 -
Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma
Onken MD, Worley LA, Person E, Char DH, Bowcock AM, Harbour JW Clinical Cancer Research 2007 May 13 2923-2927 -
Transcriptomic versus chromosomal prognostic markers and clinical outcome in uveal melanoma
Worley LA, Onken MD, Person E, Robirds D, Branson J, Char DH, Perry A, Harbour JW Clinical Cancer Research 2007 Mar 13 1466-1471 -
Cellular and genetic events in retinoblastoma tumorigenesis
Dyer MA, Harbour JW 2007 Mar 405-409 -
Cancer genetics
Harbour JW, Onken MD 2007 Mar 31-33 -
Cancer Genetics
Harbour JW, Onken MD 2007 31-33 -
Molecular pathobiology of uveal melanoma
Ehlers JP, Harbour JW International ophthalmology clinics 2006 Dec 46 167-180 -
Prognostic testing in uveal melanoma by transcriptomic profiling of fine needle biopsy specimens
Onken MD, Worley LA, Dávilla RM, Char DH, Harbour JW Journal of Molecular Diagnostics 2006 Nov 8 567-573 -
Rb at the interface between cell cycle and apoptotic decisions
Delston RB, Harbour JW Current molecular medicine 2006 Nov 6 713-718 -
Eye cancer: Unique insights into oncogenesis: The Cogan lecture
Harbour JW Investigative Ophthalmology and Visual Science 2006 May 47 1737-1745 -
Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas
Onken MD, Ehlers JP, Worley LA, Makita J, Yokota Y, Harbour JW Cancer research 2006 May 66 4602-4609 -
Lipid exudation following plaque radiotherapy for posterior uveal melanoma
Mills MD, Harbour JW American journal of ophthalmology 2006 Mar 141 594-595.e1 -
Association between microarray gene expression signature and extravascular matrix patterns in primary uveal melanomas
Onken MD, Lin AY, Worley LA, Folberg R, Harbour JW American journal of ophthalmology 2005 Oct 140 748-749 -
Retinoblastoma
Murphree AL, Samuel MA, Harbour JW, Mansfield NC 2005 Sep 1-3 557-607 -
DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma
Ehlers JP, Worley L, Onken MD, Harbour JW Clinical Cancer Research 2005 May 11 3609-3613 -
Uveal melanoma: Genetic aspects
Singh AD, Damato B, Howard P, Harbour JW Ophthalmology Clinics of North America 2005 Mar 18 85-97 -
NBS1 expression as a prognostic marker in uveal melanoma
Ehlers JP, Harbour JW Clinical Cancer Research 2005 Mar 11 1849-1853 -
Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase
Lieman JH, Worley LA, Harbour JW Journal of Biological Chemistry 2005 Mar 280 10484-10490 -
Functional analysis of the p53 pathway in response to ionizing radiation in uveal melanoma
Sun Y, Tran BN, Worley LA, Delston RB, Harbour JW Investigative Ophthalmology and Visual Science 2005 46 1561-1564 -
MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A
Loercher AE, Tank EM, Delston RB, Harbour JW Journal of Cell Biology 2005 Jan 168 35-40 -
Fine needle aspiration biopsy with adjunct immunohistochemistry in intraocular tumor management
Faulkner-Jones BE, Foster WJ, Harbour JW, Smith ME, Dávila RM Acta Cytologica 2005 49 297-308 -
Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death
Onken MD, Worley LA, Ehlers JP, Harbour JW Cancer research 2004 Oct 64 7205-7209 -
What is the best treatment for retinoblastoma?
Harbour JW American journal of ophthalmology 2004 Sep 138 471-473 -
Photodynamic therapy for choroidal metastasis from carcinoid tumor
Harbour JW American journal of ophthalmology 2004 Jun 137 1143-1145 -
For whom the bell tolls: Susceptibility to common adult cancers in retinoblastoma survivors
Kay FJ, Harbour JW Journal of the National Cancer Institute 2004 Mar 96 342-343 -
Association between choroidal pigmentation and posterior uveal melanoma in a white population
Harbour JW, Brantley MA, Hollingsworth H, Gordon M British Journal of Ophthalmology 2004 Jan 88 39-43 -
Cytologic diagnosis of intraocular lymphoma in vitreous aspirates
Farkas T, Harbour JW, Dávila RM Acta Cytologica 2004 48 487-491 -
Association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi
Harbour JW, Brantley MA, Hollingsworth H, Gordon M British Journal of Ophthalmology 2004 Jan 88 36-38 -
Optical coherence tomography in the evaluation of retinal changes associated with suspicious choroidal melanocytic tumors
Espinoza G, Rosenblatt B, Harbour JW American journal of ophthalmology 2004 Jan 137 90-95 -
Transpupillary Thermotherapy versus Plaque Radiotherapy for Suspected Choroidal Melanomas
Harbour JW, Meredith TA, Thompson PA, Gordon ME Ophthalmology 2003 Nov 110 2207-2214 -
Status of the NF1 tumor suppressor locus in uveal melanoma
Foster WJ, Fuller CE, Perry A, Harbour JW Archives of Ophthalmology 2003 Sep 121 1311-1315 -
Pars plana vitrectomy in eyes containing a treated posterior uveal melanoma
Foster WJ, Harbour JW, Holekamp NM, Shah GK, Thomas MA American journal of ophthalmology 2003 Sep 136 471-476 -
Molecular genetics of uveal melanoma
Loercher AE, Harbour JW Current Eye Research 2003 Aug 27 69-74 -
Ocular melanoma: A review and the relationship to cutaneous melanoma
Hurst EA, Harbour JW, Cornelius LA Archives of Dermatology 2003 Aug 139 1067-1073 -
Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb
Ma D, Zhou P, Harbour JW Journal of Biological Chemistry 2003 May 278 19358-19366 -
Rate of resolution of exudative retinal detachment after plaque radiotherapy for uveal melanoma
Harbour JW, Ahmad S, El-Bash M Archives of Ophthalmology 2002 Nov 120 1463-1469 -
Transducible peptide therapy for uveal melanoma and retinoblastoma
Harbour JW, Worley L, Ma D, Cohen M Archives of Ophthalmology 2002 Oct 120 1341-1346 -
Altered expression of Rb and p53 in uveal melanomas following plaque radiotherapy
Brantley MA, Worley L, Harbour JW American journal of ophthalmology 2002 133 242-248 -
Photodynamic therapy for circumscribed choroidal hemangioma
Sheidow TG, Harbour JW Canadian Journal of Ophthalmology 2002 37 314-317 -
Risk factors for metastasis in retinoblastoma
Finger PT, Harbour JW, Karcioglu ZA Survey of Ophthalmology 2002 47 1-16 -
Control of exit from g1 and s phases of the cell cycle by histone deacetylase–rb-hswi/snf and rb-hswi/snf repressor complexes
Gavin M, Zhang S, Dahiya A, Luo R, Postigo A, Ma D, Harbour W, Dean D Nature genetics 2001 Apr 27 55 -
Molecular basis of low-penetrance retinoblastoma
Harbour JW Archives of Ophthalmology 2001 119 1699-1704 -
The molecular biology of retinoblastoma
Brantley J, Harbour JW Ocular Immunology and Inflammation 2001 9 1-8 -
The Rb/E2F pathway: Expanding roles and emerging paradigms
Harbour JW, Dean DC Genes and Development 2000 Oct 14 2393-2409 -
Inactivation of retinoblastoma protein in uveal melanoma by phosphorylation of sites in the COOH-terminal region
Brantley J, Harbour JW Cancer research 2000 Aug 60 4320-4323 -
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and RB-hSWI/SNF
Zhang HS, Gavin M, Dahiya A, Postigo AA, Ma D, Luo RX, Harbour JW, Dean DC Cell 2000 Mar 101 79-89 -
Rb function in cell-cycle regulation and apoptosis
Harbour JW, Dean DC Nature cell biology 2000 2 E65-E67 -
Chromatin remodeling and Rb activity
Harbour JW, Dean DC Current Opinion in Cell Biology 2000 12 685-689 -
Deregulation of the Rb and p53 pathways in uveal melanoma
Brantley J, Harbour JW American Journal of Pathology 2000 157 1795-1801 -
Corepressors and retinoblastoma protein function
Harbour JW, Dean DC Current topics in microbiology and immunology 2000 254 137-144 -
Tumor suppressor genes in ophthalmology
Harbour JW Survey of Ophthalmology 1999 Nov 44 235-246 -
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1
Harbour JW, Luo RX, Dei Santi A, Postigo AA, Dean DC Cell 1999 Sep 98 859-869 -
Overview of RB gene mutations in patients with retinoblastoma: Implications for clinical genetic screening
Harbour JW Ophthalmology 1998 Aug 105 1442-1447 -
Solitary fibrous tumor of the orbit
Char D, Weidner N, Ahn J, Harbour JW Orbit 1997 16 113-118 -
Regulation of retinoblastoma protein activity by the c terminal domain
Harbour JW, Luo RX Investigative Ophthalmology and Visual Science 1997 38 S384 -
Metastatic risk for distinct patterns of postirradiation local recurrence of posterior uveal melanoma
Harbour JW, Char DH, Kroll S, Quivey JM, Castro J, Gragoudas ES, Egan KM Ophthalmology 1997 104 1785-1793 -
Langerhans cell histiocytosis diagnosed by fine needle biopsy
Harbour JW, Char DH, Ljung BM, Luna-Fineman S Archives of Ophthalmology 1997 115 1212 -
Pars plana vitrectomy in the management of phakic and pseudophakic malignant glaucoma
William Harbour J, Rubsamen PE, Palmberg P Archives of Ophthalmology 1996 Sep 114 1073-1078 -
Local carboplatin therapy in transgenic murine retinoblastoma
Harbour JW, Murray TG, Hamasaki D, Cicciarelli N, Hernández E, Smith B, Windle J, O'Brien JM Investigative Ophthalmology and Visual Science 1996 Aug 37 1892-1898 -
Intraoperative echographic localization of iodine 125 episcleral radioactive plaques for posterior uveal melanoma
William Harbour J, Murray TG, Byrne SF, Randall Hughes J, Kym Gendron E, Ehlies FJ, Markoe AM Retina 1996 16 129-134 -
Vitrectomy for diabetic macular edema associated with a thickened and taut posterior hyaloid membrane
Harbour JW, Smiddy WE, Flynn HW, Rubsamen PE American journal of ophthalmology 1996 121 405-413 -
Pars plana vitrectomy for chronic pseudophakic cystoid macular edema
Harbour JW, Smiddy WE, Rubsamen PE, Murray TG, Davis JL, Flynn HW American journal of ophthalmology 1995 120 302-307 -
Initial Management and Follow-up of Melanocytic Iris Tumors
Harbour JW, Augsburger JJ, Eagle RC Ophthalmology 1995 102 1987-1993 -
Uveal Metastasis from Carcinoid Tumor: Clinical Observations in Nine Cases
Harbour JW, De Potter P, Shields CL, Shields JA Ophthalmology 1994 101 1084-1090 -
Expression in lung cancer of a transcribed sequence at the DNF15S2 locus at chromosome 3P21
Harbour JW, Lai SL, Gazdar AF, Minna JD, Kaye FJ Anticancer Research 1990 10 23-27 -
Loss of heterozygosity in a gene coding for a thyroid hormone receptor in lung cancers
Leduc F, Brauch H, Hajj C, Dobrovic A, Kaye F, Gazdar A, Harbour JW, Pettengill OS, Sorenson GD, Van Den Berg A, Kok K, Campling B, Paquin F, Bradley WE, Zbar B, Minna J, Buys C, Ayoub J American Journal of Human Genetics 1989 44 282-287 -
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC
Harbour JW, Lai SL, Whang-Peng J, Gazdar AF, Minna JD, Kaye FJ Science 1988 241 353-357
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15-Gene Expression Profile and PRAME as Integrated Prognostic Test for Uveal Melanoma: First Report of Collaborative Ocular Oncology Group Study No. 2 (COOG2.1)
Research
- Genetics and genomics of ocular cancer
- Prognostic biomarkers for ocular cancer
- Mechanisms of metastasis in ocular cancer
- Molecular targeted therapies for ocular cancer
Clinical Focus
- Ocular oncology
- Retinoblastoma
- Uveal melanoma
- Ocular Lymphoma
Articles by Dr. Harbour
Results: 1 Locations
Ophthalmology Clinic
at James W. Aston Ambulatory Care Center 5303 Harry Hines Blvd., 6th FloorDallas, Texas 75390 214-645-2020 Monday-Friday: 7 a.m. to 6 p.m. Directions to Ophthalmology Clinic Parking Info for Ophthalmology Clinic