Jacobo Santolaya, M.D.

Pediatrics - Gastroenterology
Autoimmune conditions of the gastrointestinal tract
Diagnosis and treatment of inflammatory bowel disease in pediatric patients

Biography

Jacobo Santolaya, M.D., is an Assistant Professor in the Department of Pediatrics at UT Southwestern Medical Center. He specializes in pediatric gastroenterology.

Dr. Santolaya earned his medical degree at Rutgers Robert Wood Johnson Medical School. He completed a residency in pediatrics at the Children’s Hospital of Philadelphia and gained advanced training through a fellowship in pediatric gastroenterology at UT Southwestern.

Board certified in general pediatrics, he joined the UT Southwestern faculty in 2022.

Dr. Santolaya's clinical interests include inflammatory bowel disease in pediatric patients, autoimmune conditions of the gastrointestinal tract, and microbiome associations with intestinal inflammation. He also sees patients with various general gastroenterology disorders, including constipation, gastroesophageal reflux disease, and nutritional deficiencies.

He is a member of the American Academy of Pediatrics and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.

Education & Training

Medical School - Rutgers Robert Wood Johnson Medical School (2012-2016)
Residency - Children's Hospital of Philadelphia (2016-2019), Pediatrics
Fellowship - UT Southwestern/Children's Medical Center (2019-2022), Pediatric Gastroenterology

Professional Associations & Affiliations

American Academy of Pediatrics
North American Society for Pediatric Gastroenterology, Hepatology and Nutrition

Honors & Awards

Senior Fellow Research Day - Top 5 Abstract / Oral Presentation 2022, UT Southwestern Medical Center Department of Pediatrics
Outstanding Advocate Achievement 2019, Children’s Hospital of Philadelphia Community Pediatrics & Advocacy Program for Senior Residency Advocacy Project
Alpha Omega Alpha Honor Medical Society 2015, Rutgers Robert Wood Johnson Medical School
Gold Humanism Honor Society 2015, Rutgers Robert Wood Johnson Medical School
Volunteer Award 2014, Department of Obstetrics and Gynecology at Rutgers Robert Wood Johnson Medical School
Distinction in Research 2012-2013, Department of Obstetrics and Gynecology at Rutgers Robert Wood Johnson Medical School

Books & Publications

Publications
- CAPTURE IBD: Advancing Precision Medicine in Pediatric IBD
  Subedi S, Albenbergl LG, Bass JA, Bauman L, Chevalier R, Egberg M, Goyal A, Hoffenberg E, Huang J, Kelsen JR, Kugathasan S, Minar P, Niklinska-Schirtz BJ, Ouahed J, Perry CE, Rabizadeh S, Rosen MJ, Santolaya J, Sauer CG, Shapiro JM, Sifuentes-Domingue L, Sylvester F, Villarreal M, Weaver SA, Whaley KG, Ziring D, De Zoeten EF, Kahn SA Inflammatory bowel diseases 2026 Jan 32 188-190
- Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism
  Tan S, Santolaya JL, Wright TF, Liu Q, Fujikawa T, Chi S, Bergstrom CP, Lopez A, Chen Q, Vale G, McDonald JG, Schmidt A, Vo N, Kim J, Baniasadi H, Li L, Zhu G, He TC, Zhan X, Obata Y, Jin A, Jia D, Elmquist JK, Sifuentes-Dominguez L, Burstein E Nature Metabolism 2024 Jun 6 1076-1091
- Bioavailability of the tumor necrosis factor alpha/regulated on activation, normal T cell expressed and secreted (RANTES) biosystem inside the gestational sac during the pre-immune stages of embryo development
  Santolaya JL, Schweer DS, Cardenas-Goicoechea J, Bukowski R, Santolaya-Forgas J Journal of Perinatal Medicine 2023 Sep 51 891-895
- Enhancing Residents' Warmth in Greeting Caregivers: An Inpatient Intervention to Improve Family-Centered Communication
  Bayer ND, Taylor A, Atabek Z, Santolaya JL, Bamat TW, Washington N Journal for Healthcare Quality 2021 May 43 183-193
- Pediatric Residents’ Sense of Meaning in Their Work: Is This Value Related to Higher Specialty Satisfaction and Reduced Burnout?
  Bayer ND, Taylor A, Fallon A, Wang H, Santolaya JL, Bamat TW, Washington N Academic Pediatrics 2021 Apr 21 557-563
- Should we call you mom and dad? Caregiver preferences and pediatric physician and nurse manner in greetings
  Bayer ND, Taylor A, Atabek Z, Santolaya J, Bamat TW, Washington N Hospital Pediatrics 2019 Dec 9 989-992
- Association of histological chorioamnionitis and magnesium sulfate treatment in singleton and dichorionic twin pregnancies with preterm premature rupture of membranes: Preliminary observations
  O'Brien JM, Santolaya JL, Palomares K, Blitzer D, Santolaya-Forgas J Journal of Perinatal Medicine 2018 Oct 46 839-844
- The Microbiota and Transgenomic Networks: Potential Implications for Maternal-Fetal Medicine
  Santolaya-Forgas J, Townsend R, Santolaya JL, Patel P, Herrera-Garcia G, Castracane VD Fetal Diagnosis and Therapy 2016 Jan 39 1-3
- A pressing need for culturally relevant preconception programs for obese patients in the USA
  O'Brien J, Santolaya JL, Townsend R, Matta P, Canterino J, Santolaya-Forgas J Journal of Neonatal-Perinatal Medicine 2015 Jul 8 169-170
- Risk factors for perinatal mortality in patients admitted to the hospital with the diagnosis of placental abruption
  Atkinson AL, Santolaya-Forgas J, Blitzer DN, Santolaya JL, Matta P, Canterino J, Oyelese Y Journal of Maternal-Fetal and Neonatal Medicine 2015 Mar 28 594-597
- Ebola viral infection in pregnancy: A plea for specific clinical recommendations
  Santolaya JL, Santolaya-Forgas J Journal of Perinatal Medicine 2015 Jan 43 123-124
- Screening for Down syndrome in dichorionic twin pregnancies conceived by in vitro fertilization (IVF): A clinical pilot study to confirm the laboratory methods
  Francois L, Kugler L, Santolaya JL, Faro R, Di Stefano V, Merjanian L, Santolaya-Forgas J Journal of assisted reproduction and genetics 2014 Jan 31 125-128
- Baseline TNFα operational capacity in fetal and maternal circulation prior to the onset of labor: "tuned for different purposes"
  Santolaya JL, Kugler L, Francois L, Stefano VD, Ebert GA, Wolf R, Wang B, Santolaya-Forgas J Reproductive Sciences 2013 Jul 20 838-844
- Candidate Biomarkers for Acute Rejection of Pregnancy After in-utero Cell-Based Therapy in Pre-Immune Embryos via Ultrasound-Guided Celocentesis
  Santolaya JL, Galan I, Stefano VD, Jasani S, De Leon-Luis J, Wolf R, Santolaya-Forgas J American Journal of Reproductive Immunology 2012 Aug 68 181-184
- Acute changes in the embryonic heart rate: A response to environmental challenges?
  Santolaya JL, Di Stefano V, Deleon Luis J, Santolaya-Forgas J Ultrasound in Obstetrics and Gynecology 2012 Apr 39 480-481

Research

Clinical and quality improvement research related to inflammatory bowel disease in pediatric patients
Basic science research on colonic enteroendocrine cells and their effect on host metabolism and microbiome

Clinical Focus

Autoimmune conditions of the gastrointestinal tract
Diagnosis and treatment of inflammatory bowel disease in pediatric patients
General gastroenterology disorders in pediatric patients
Microbiome associations with intestinal inflammation

New Patient Appointment