Jean-Antoine Ribeil, M.D., Ph.D.

Jean-Antoine Ribeil, M.D., Ph.D.

Director, Comprehensive Adult Sickle Cell Disease Program

  • Internal Medicine - Hematology/Oncology
  • Hematology
  • Red Blood Cell Disorders

Biography

Jean-Antoine Ribeil, M.D., Ph.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He is an internationally recognized hematologist and scientific investigator who specializes in red blood cell disorders such as sickle cell disease and thalassemia.

Dr. Ribeil earned his medical degree at the University of Limoges in France and his doctorate in blood cell biology at Paris VII University. He completed a residency in hematology and oncology at the University of Limoges. He gained advanced training through clinical fellowships in intensive care, internal medicine, and hematology at the University of Limoges and Necker-Enfants Malades Hospital/Paris V Descartes University in Paris. He also completed a research fellowship in hematopoiesis and immunology at the French National Centre for Scientific Research in Paris.

He joined the UT Southwestern faculty in 2025 and serves as Director of UT Southwestern’s Comprehensive Adult Sickle Cell Disease Center. Before joining UT Southwestern, Dr. Ribeil served as an associate professor at Boston University School of Medicine and was clinical director and then director of the Sickle Cell Center of Excellence, co-director of the Hereditary Hemorrhagic Telangiectasia Clinic, and principal investigator of the GLOB Lab at Boston Medical Center.

Dr. Ribeil has a strong focus on translational research and the development of gene therapy for hemoglobinopathies such as sickle cell disease and thalassemia. He has served as principal investigator or co-investigator on numerous industry- and foundation-supported studies and clinical trials evaluating novel pharmacologic agents, red blood cell exchange strategies, and innovative care models for people living with sickle cell disease. He is the former medical director of the gene therapy sickle cell disease program at Bluebird Bio in Cambridge, Massachusetts, and the founder and CEO of GLOB Therapy Consulting. He has delivered numerous regional and international invited lectures, contributed to textbooks, and published more than 80 academic articles related to his areas of expertise.

Dr. Ribeil is a member of the American Society of Gene & Cell Therapy and the American Society of Hematology. He serves on the editorial board of the American Journal of Hematology. He previously served on French national committees for the Sickle Cell Disease Centers of Excellence and the Thrombotic Microangiopathy Centers of Excellence.

Personal Note

When he’s not at work, Dr. Ribeil enjoys travelling with his family, bicycling with friends, and cooking.

  • Graduate School - Aix-Marseille University: Faculty of Medical and Paramedical Sciences (1991-1995)
  • Medical School - University of Limoges, France (1995-2001)
  • Internship - University of Limoges, France (1995-2001), Hematology Oncology
  • Clinical Fellowship - Necker-Enfants Malades Hospital, France (2001-2001), Hematology
  • American Society of Gene & Cell Therapy
  • American Society of Hematology
  • Integrated Pilot Award Program 2024-2025, Boston University and Translational Science Institute
  • Translational research for hemoglobinopathies such as sickle cell disease and thalassemia
  • The development of gene therapy for hemoglobinopathies

Clinical Focus

  • Hematology
  • Red Blood Cell Disorders
  • Sickle Cell Disease
  • Thalassemia

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