- American Society of Gene & Cell Therapy
- American Society of Hematology
Jean-Antoine Ribeil, M.D., Ph.D.
Director, Comprehensive Adult Sickle Cell Disease Program
- Internal Medicine - Hematology/Oncology
- Hematology
- Red Blood Cell Disorders
Biography
Jean-Antoine Ribeil, M.D., Ph.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He is an internationally recognized hematologist and scientific investigator who specializes in red blood cell disorders such as sickle cell disease and thalassemia.
Dr. Ribeil earned his medical degree at the University of Limoges in France and his doctorate in blood cell biology at Paris VII University. He completed a residency in hematology and oncology at the University of Limoges. He gained advanced training through clinical fellowships in intensive care, internal medicine, and hematology at the University of Limoges and Necker-Enfants Malades Hospital/Paris V Descartes University in Paris. He also completed a research fellowship in hematopoiesis and immunology at the French National Centre for Scientific Research in Paris.
He joined the UT Southwestern faculty in 2025 and serves as Director of UT Southwestern’s Comprehensive Adult Sickle Cell Disease Center. Before joining UT Southwestern, Dr. Ribeil served as an associate professor at Boston University School of Medicine and was clinical director and then director of the Sickle Cell Center of Excellence, co-director of the Hereditary Hemorrhagic Telangiectasia Clinic, and principal investigator of the GLOB Lab at Boston Medical Center.
Dr. Ribeil has a strong focus on translational research and the development of gene therapy for hemoglobinopathies such as sickle cell disease and thalassemia. He has served as principal investigator or co-investigator on numerous industry- and foundation-supported studies and clinical trials evaluating novel pharmacologic agents, red blood cell exchange strategies, and innovative care models for people living with sickle cell disease. He is the former medical director of the gene therapy sickle cell disease program at Bluebird Bio in Cambridge, Massachusetts, and the founder and CEO of GLOB Therapy Consulting. He has delivered numerous regional and international invited lectures, contributed to textbooks, and published more than 80 academic articles related to his areas of expertise.
Dr. Ribeil is a member of the American Society of Gene & Cell Therapy and the American Society of Hematology. He serves on the editorial board of the American Journal of Hematology. He previously served on French national committees for the Sickle Cell Disease Centers of Excellence and the Thrombotic Microangiopathy Centers of Excellence.
Personal Note
When he’s not at work, Dr. Ribeil enjoys travelling with his family, bicycling with friends, and cooking.
Education & Training
- Graduate School - Aix-Marseille University: Faculty of Medical and Paramedical Sciences (1991-1995)
- Medical School - University of Limoges, France (1995-2001)
- Internship - University of Limoges, France (1995-2001), Hematology Oncology
- Clinical Fellowship - Necker-Enfants Malades Hospital, France (2001-2001), Hematology
Professional Associations & Affiliations
Honors & Awards
- Integrated Pilot Award Program 2024-2025, Boston University and Translational Science Institute
Books & Publications
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Books
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French Edition of the Guidelines for the Management of Transfusion-Dependent Thalassemia
Ribeil J-A, Chevillon F, Joseph L (2022), Nicosia, Cyprus, Thalassemia International Federation -
Pregnancy and sickle cell disease in Maternal Pathologies and Pregnancy (2nd ed.)
Ribeil J-A, Benachi A (2022), Paris, France, Elsevier Masson -
French Edition of the Guidelines for the Management of Non–Transfusion-Dependent Thalassemia
Ribeil J-A, Chevillon F, Joseph L (2017), Nicosia, Cyprus, Thalassemia International Federation -
French Edition of the Guidelines for the Management of Transfusion-Dependent Thalassemia
Ribeil J-A, Delville M, Joseph L (2016), Nicosia, Cyprus, Thalassemia International Federation -
Thalassemic syndromes in Encyclopédie Medico-Chirurgicale
De Montalembert M, Ribeil J-A (2016) -
Pregnancy and sickle cell disease in Maternal Pathologies and Pregnancy
Ribeil J-A, Benachi A (2014), Paris, France, Elsevier Masson -
How I treat hemoglobinopathies in Livre de l’Interne: Hématologie
Ribeil J-A (2012), Paris, France, Lavoisier -
Hematopoiesis in Blood Transfusion
Lefrere F, Ribeil J-A (2011), Paris, France, Elsevier Masson -
Regulation of erythropoiesis in Handbook: Disorders of Erythropoiesis, Erythrocytes and Iron Metabolism
Vandekerkove J, Courtois G, Coulon S, Ribeil J-A, Hermine O (2009), European School of Haematology
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French Edition of the Guidelines for the Management of Transfusion-Dependent Thalassemia
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Publications
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Selective AMPKβ1 activation induces fetal hemoglobin in human erythroid cells and sickle cell mice via the noncanonical NRF2 pathway.
Hara Y, Lemgart VT, Lessard S, Mercadante CJ, Ribeil JA, Hicks A, Rimmele P, Light DR, Science advances 2025 Nov 11 47 eadx1144 -
From Where It Stems.
Shapira-Daniels A, Pareek K, Cozzolino M, Ribeil JA, Awtry E, The New England journal of medicine 2025 Jun 392 21 2151-2158 -
Initial outcomes in a sickle cell disease transition clinic.
Madrazo-Aguirre K, Ribeil JA, Sobota AE, Health care transitions 2024 2 100056 -
Gene-addition/editing therapy in sickle cell disease.
Pollock G, Negre O, Ribeil JA, Presse medicale (Paris, France : 1983) 2023 Dec 52 4 104214 -
An integrated therapeutic approach to sickle cell disease management beyond infancy.
Ribeil JA, Pollock G, Frangoul H, Steinberg MH, American journal of hematology 2023 Jul 98 7 1087-1096 -
SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells.
Hara Y, Lemgart VT, Halland N, Mahdaviani K, Ribeil JA, Lessard S, Hicks A, Light DR, Blood advances 2023 Jun 7 11 2317-2323 -
Lovo-cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB-206 study.
Kanter J, Thompson AA, Pierciey FJ, Hsieh M, Uchida N, Leboulch P, Schmidt M, Bonner M, Guo R, Miller A, Ribeil JA, Davidson D, Asmal M, Walters MC, Tisdale JF, American journal of hematology 2023 Jan 98 1 11-22 -
Pregnancy outcome in women with transfused beta-thalassemia in France.
Virot E, Thuret I, Jardel S, Herbrecht R, Lachenal F, Lionnet F, Lucchini MJ, Machin J, Nimubona S, Ribeil JA, Galacteros F, Cannas G, Hot A, Annals of hematology 2022 Feb 101 2 289-296 -
Biologic and Clinical Efficacy of LentiGlobin for Sickle Cell Disease.
Kanter J, Walters MC, Krishnamurti L, Mapara MY, Kwiatkowski JL, Rifkin-Zenenberg S, Aygun B, Kasow KA, Pierciey FJ, Bonner M, Miller A, Zhang X, Lynch J, Kim D, Ribeil JA, Asmal M, Goyal S, Thompson AA, Tisdale JF, The New England journal of medicine 2022 Feb 386 7 617-628 -
Primary myelofibrosis in untreated sickle cell disease: Are adult patients at higher risk for developing hematological myeloid neoplasms?
Ribeil JA, American journal of hematology 2022 Jan 97 1 4-6 -
Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial.
Magrin E, Semeraro M, Hebert N, Joseph L, Magnani A, Chalumeau A, Gabrion A, Roudaut C, Marouene J, Lefrere F, Diana JS, Denis A, Neven B, Funck-Brentano I, Negre O, Renolleau S, Brousse V, Kiger L, Touzot F, Poirot C, Bourget P, El Nemer W, Blanche S, Tréluyer JM, Asmal M, Walls C, Beuzard Y, Schmidt M, Hacein-Bey-Abina S, Asnafi V, Guichard I, Poirée M, Monpoux F, Touraine P, Brouzes C, de Montalembert M, Payen E, Six E, Ribeil JA, Miccio A, Bartolucci P, Leboulch P, Cavazzana M, Nature medicine 2022 Jan 28 1 81-88 -
Effect of hydroxyurea exposure before puberty on sperm parameters in males with sickle cell disease.
Joseph L, Jean C, Manceau S, Chalas C, Arnaud C, Kamdem A, Pondarré C, Habibi A, Bernaudin F, Allali S, de Montalembert M, Boutonnat-Faucher B, Arlet JB, Koehl B, Cavazzana M, Ribeil JA, Lionnet F, Berthaut I, Brousse V, Blood 2021 Feb 137 6 826-829 -
Sickle Cell Trait Modulates the Proteome and Phosphoproteome of Plasmodium falciparum-Infected Erythrocytes.
Chauvet M, Chhuon C, Lipecka J, Dechavanne S, Dechavanne C, Lohezic M, Ortalli M, Pineau D, Ribeil JA, Manceau S, Le Van Kim C, Luty AJF, Migot-Nabias F, Azouzi S, Guerrera IC, Merckx A, Frontiers in cellular and infection microbiology 2021 11 637604 -
Safety and feasibility of hematopoietic progenitor stem cell collection by mobilization with plerixafor followed by apheresis vs bone marrow harvest in patients with sickle cell disease in the multi-center HGB-206 trial.
Tisdale JF, Pierciey FJ, Bonner M, Thompson AA, Krishnamurti L, Mapara MY, Kwiatkowski JL, Shestopalov I, Ribeil JA, Huang W, Asmal M, Kanter J, Walters MC, American journal of hematology 2020 Sep 95 9 E239-E242 -
A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease.
McArthur JG, Svenstrup N, Chen C, Fricot A, Carvalho C, Nguyen J, Nguyen P, Parachikova A, Abdulla F, Vercellotti GM, Hermine O, Edwards D, Ribeil JA, Belcher JD, Maciel TT, Haematologica 2020 Mar 105 3 623-631 -
Primary Hyperparathyroidism in Sickle Cell Disease: An Unknown Complication of the Disease in Adulthood.
Denoix E, Bomahou C, Clavier L, Ribeil JA, Lionnet F, Bartolucci P, Courbebaisse M, Pouchot J, Arlet JB, Journal of clinical medicine 2020 Jan 9 2 -
Innovative Curative Treatment of Beta Thalassemia: Cost-Efficacy Analysis of Gene Therapy Versus Allogenic Hematopoietic Stem-Cell Transplantation.
Coquerelle S, Ghardallou M, Rais S, Taupin P, Touzot F, Boquet L, Blanche S, Benaouadi S, Brice T, Tuchmann-Durand C, Ribeil JA, Magrin E, Lissillour E, Rochaix L, Cavazzana M, Durand-Zaleski I, Human gene therapy 2019 Jun 30 6 753-761 -
Sotatercept, a novel transforming growth factor β ligand trap, improves anemia in β-thalassemia: a phase II, open-label, dose-finding study.
Cappellini MD, Porter J, Origa R, Forni GL, Voskaridou E, Galactéros F, Taher AT, Arlet JB, Ribeil JA, Garbowski M, Graziadei G, Brouzes C, Semeraro M, Laadem A, Miteva D, Zou J, Sung V, Zinger T, Attie KM, Hermine O, Haematologica 2019 Mar 104 3 477-484 -
Sickle SCAN™ (BioMedomics) fulfills analytical conditions for neonatal screening of sickle cell disease.
Nguyen-Khoa T, Mine L, Allaf B, Ribeil JA, Remus C, Stanislas A, Gauthereau V, Enouz S, Kim JS, Yang X, Gluckman E, Beaudeux JL, Munnich A, Girot R, Cavazzana M, Annales de biologie clinique 2018 Aug 76 4 416-420 -
Transfusion-related adverse events are decreased in pregnant women with sickle cell disease by a change in policy from systematic transfusion to prophylactic oxygen therapy at home: A retrospective survey by the international sickle cell disease observatory.
Ribeil JA, Labopin M, Stanislas A, Deloison B, Lemercier D, Habibi A, Albinni S, Charlier C, Lortholary O, Lefrere F, De Montalembert M, Blanche S, Galactéros F, Tréluyer JM, Gluckman E, Ville Y, Joseph L, Delville M, Benachi A, Cavazzana M, American journal of hematology 2018 Jun 93 6 794-802 -
Plerixafor enables safe, rapid, efficient mobilization of hematopoietic stem cells in sickle cell disease patients after exchange transfusion.
Lagresle-Peyrou C, Lefrère F, Magrin E, Ribeil JA, Romano O, Weber L, Magnani A, Sadek H, Plantier C, Gabrion A, Ternaux B, Félix T, Couzin C, Stanislas A, Tréluyer JM, Lamhaut L, Joseph L, Delville M, Miccio A, André-Schmutz I, Cavazzana M, Haematologica 2018 May 103 5 778-786 -
High bone mineral density in sickle cell disease: Prevalence and characteristics.
De Luna G, Ranque B, Courbebaisse M, Ribeil JA, Khimoud D, Dupeux S, Silvera J, Offredo L, Pouchot J, Arlet JB, Bone 2018 May 110 199-203 -
Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia.
Thompson AA, Walters MC, Kwiatkowski J, Rasko JEJ, Ribeil JA, Hongeng S, Magrin E, Schiller GJ, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Bourget P, Magnani A, Caccavelli L, Diana JS, Suarez F, Monpoux F, Brousse V, Poirot C, Brouzes C, Meritet JF, Pondarré C, Beuzard Y, Chrétien S, Lefebvre T, Teachey DT, Anurathapan U, Ho PJ, von Kalle C, Kletzel M, Vichinsky E, Soni S, Veres G, Negre O, Ross RW, Davidson D, Petrusich A, Sandler L, Asmal M, Hermine O, De Montalembert M, Hacein-Bey-Abina S, Blanche S, Leboulch P, Cavazzana M, The New England journal of medicine 2018 Apr 378 16 1479-1493 -
Indications and outcome of splenectomy in hematologic disease.
Bonnet S, Guédon A, Ribeil JA, Suarez F, Tamburini J, Gaujoux S, Journal of visceral surgery 2017 Dec 154 6 421-429 -
Roles of APOL1 G1 and G2 variants in sickle cell disease patients: kidney is the main target.
Kormann R, Jannot AS, Narjoz C, Ribeil JA, Manceau S, Delville M, Joste V, Prié D, Pouchot J, Thervet E, Courbebaisse M, Arlet JB, British journal of haematology 2017 Oct 179 2 323-335 -
[Gene therapy for sickle cell disease].
Ribeil JA, Blanche S, Cavazzana M, Medecine sciences : M/S 2017 May 33 5 463-465 -
Gene Therapy in a Patient with Sickle Cell Disease.
Ribeil JA, Hacein-Bey-Abina S, Payen E, Magnani A, Semeraro M, Magrin E, Caccavelli L, Neven B, Bourget P, El Nemer W, Bartolucci P, Weber L, Puy H, Meritet JF, Grevent D, Beuzard Y, Chrétien S, Lefebvre T, Ross RW, Negre O, Veres G, Sandler L, Soni S, de Montalembert M, Blanche S, Leboulch P, Cavazzana M, The New England journal of medicine 2017 Mar 376 9 848-855 -
Carboxy-terminal fragment of fibroblast growth factor 23 induces heart hypertrophy in sickle cell disease.
Courbebaisse M, Mehel H, Petit-Hoang C, Ribeil JA, Sabbah L, Tuloup-Minguez V, Bergerat D, Arlet JB, Stanislas A, Souberbielle JC, Le Clésiau H, Fischmeister R, Friedlander G, Prié D, Haematologica 2017 Feb 102 2 e33-e35 -
Arterio-venous fistula for automated red blood cells exchange in patients with sickle cell disease: Complications and outcomes.
Delville M, Manceau S, Ait Abdallah N, Stolba J, Awad S, Damy T, Gellen B, Sabbah L, Debbache K, Audard V, Beaumont JL, Arnaud C, Chantalat-Auger C, Driss F, Lefrère F, Cavazzana M, Franco G, Galacteros F, Ribeil JA, Gellen-Dautremer J, American journal of hematology 2017 Feb 92 2 136-140 -
Cardiac iron overload in chronically transfused patients with thalassemia, sickle cell anemia, or myelodysplastic syndrome.
de Montalembert M, Ribeil JA, Brousse V, Guerci-Bresler A, Stamatoullas A, Vannier JP, Dumesnil C, Lahary A, Touati M, Bouabdallah K, Cavazzana M, Chauzit E, Baptiste A, Lefebvre T, Puy H, Elie C, Karim Z, Ernst O, Rose C, PloS one 2017 12 3 e0172147 -
Gene Therapy with Hematopoietic Stem Cells: The Diseased Bone Marrow's Point of View.
Cavazzana M, Ribeil JA, Lagresle-Peyrou C, André-Schmutz I, Stem cells and development 2017 Jan 26 2 71-76 -
Cytoplasmic proliferating cell nuclear antigen connects glycolysis and cell survival in acute myeloid leukemia.
Ohayon D, De Chiara A, Chapuis N, Candalh C, Mocek J, Ribeil JA, Haddaoui L, Ifrah N, Hermine O, Bouillaud F, Frachet P, Bouscary D, Witko-Sarsat V, Scientific reports 2016 Oct 6 35561 -
Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β(A(T87Q))-Globin Gene.
Negre O, Eggimann AV, Beuzard Y, Ribeil JA, Bourget P, Borwornpinyo S, Hongeng S, Hacein-Bey S, Cavazzana M, Leboulch P, Payen E, Human gene therapy 2016 Feb 27 2 148-65 -
Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis.
Millet A, Martin KR, Bonnefoy F, Saas P, Mocek J, Alkan M, Terrier B, Kerstein A, Tamassia N, Satyanarayanan SK, Ariel A, Ribeil JA, Guillevin L, Cassatella MA, Mueller A, Thieblemont N, Lamprecht P, Mouthon L, Perruche S, Witko-Sarsat V, The Journal of clinical investigation 2015 Nov 125 11 4107-21 -
[French guidelines for the management of adult sickle cell disease: 2015 update].
Habibi A, Arlet JB, Stankovic K, Gellen-Dautremer J, Ribeil JA, Bartolucci P, Lionnet F, La Revue de medecine interne 2015 May 36 5 Suppl 1 5S3-84 -
A biomimetic microfluidic chip to study the circulation and mechanical retention of red blood cells in the spleen.
Picot J, Ndour PA, Lefevre SD, El Nemer W, Tawfik H, Galimand J, Da Costa L, Ribeil JA, de Montalembert M, Brousse V, Le Pioufle B, Buffet P, Le Van Kim C, Français O, American journal of hematology 2015 Apr 90 4 339-45 -
[HSP70 regulates ineffective erythropoiesis in beta-thalassaemia].
Arlet JB, Ribeil JA, Guillem F, Hermine O, Courtois G, Medecine sciences : M/S 2015 Jan 31 1 9-11 -
HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia.
Arlet JB, Ribeil JA, Guillem F, Negre O, Hazoume A, Marcion G, Beuzard Y, Dussiot M, Moura IC, Demarest S, de Beauchêne IC, Belaid-Choucair Z, Sevin M, Maciel TT, Auclair C, Leboulch P, Chretien S, Tchertanov L, Baudin-Creuza V, Seigneuric R, Fontenay M, Garrido C, Hermine O, Courtois G, Nature 2014 Oct 514 7521 242-6 -
An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia.
Dussiot M, Maciel TT, Fricot A, Chartier C, Negre O, Veiga J, Grapton D, Paubelle E, Payen E, Beuzard Y, Leboulch P, Ribeil JA, Arlet JB, Coté F, Courtois G, Ginzburg YZ, Daniel TO, Chopra R, Sung V, Hermine O, Moura IC, Nature medicine 2014 Apr 20 4 398-407 -
[HSP70, an erythropoiesis regulator that determines the fate of erythroblasts between death and differentiation].
Hermine O, Arlet JB, Ribeil JA, Guillerm F, Vandekerkhove J, Courtois G, Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 2013 May 20 2 144-7 -
A specific time course for mobilization of peripheral blood CD34+ cells after plerixafor injection in very poor mobilizer patients: impact on the timing of the apheresis procedure.
Lefrère F, Mauge L, Réa D, Ribeil JA, Dal Cortivo L, Brignier AC, Aoun C, Larghéro J, Cavazzana-Calvo M, Micléa JM, Transfusion 2013 Mar 53 3 564-9 -
Relationship between vitamin D deficiency and bone fragility in sickle cell disease: a cohort study of 56 adults.
Arlet JB, Courbebaisse M, Chatellier G, Eladari D, Souberbielle JC, Friedlander G, de Montalembert M, Prié D, Pouchot J, Ribeil JA, Bone 2013 Jan 52 1 206-11 -
Ineffective erythropoiesis in β -thalassemia.
Ribeil JA, Arlet JB, Dussiot M, Moura IC, Courtois G, Hermine O, TheScientificWorldJournal 2013 2013 394295 -
Extensive chronic GVHD is associated with donor blood CD34+ cell count after G-CSF mobilization in non-myeloablative allogeneic PBSC transplantation.
Dhédin N, Prébet T, De Latour RP, Katsahian S, Kuentz M, Piard N, Réa D, Norol F, Jouet JP, Ribeil JA, Tabrizi R, Rio B, Lioure B, Tiberghien P, Bourhis JH, Sirvent A, Bordigoni P, Blaise D, Michallet M, Vernant JP, Bone marrow transplantation 2012 Dec 47 12 1564-8 -
Determination of the best method to estimate glomerular filtration rate from serum creatinine in adult patients with sickle cell disease: a prospective observational cohort study.
Arlet JB, Ribeil JA, Chatellier G, Eladari D, De Seigneux S, Souberbielle JC, Friedlander G, de Montalembert M, Pouchot J, Prié D, Courbebaisse M, BMC nephrology 2012 Aug 13 83 -
[Abnormal tongue].
Arlet JB, Pouchot J, Ribeil JA, La Revue de medecine interne 2012 Apr 33 4 227-8 -
Thrombotic microangiopathy and Purtscher-like retinopathy as a rare presentation of juvenile dermatomyositis.
Bader-Meunier B, Monnet D, Barnerias C, Halphen I, Lambot-Juhan K, Chalumeau M, Costedoat-Chalumeau N, Ribeil JA, Bodemer C, Gherardi R, Pediatrics 2012 Mar 129 3 e821-4 -
Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes.
Frisan E, Vandekerckhove J, de Thonel A, Pierre-Eugène C, Sternberg A, Arlet JB, Floquet C, Gyan E, Kosmider O, Dreyfus F, Gabet AS, Courtois G, Vyas P, Ribeil JA, Zermati Y, Lacombe C, Mayeux P, Solary E, Garrido C, Hermine O, Fontenay M, Blood 2012 Feb 119 6 1532-42 -
[Hyperuricemia in sickle cell disease in France].
Arlet JB, Ribeil JA, Chatellier G, Pouchot J, de Montalembert M, Prié D, Courbebaisse M, La Revue de medecine interne 2012 Jan 33 1 13-7 -
Protective effect of systemic administration of erythropoietin on auditory brain stem response and compound action potential thresholds in an animal model of cochlear implantation.
Quesnel S, Nguyen Y, Campo P, Hermine O, Ribeil JA, Elmaleh M, Grayeli AB, Ferrary E, Sterkers O, Couloigner V, The Annals of otology, rhinology, and laryngology 2011 Nov 120 11 737-47 -
Vitronectin dictates intraglomerular fibrinolysis in immune-mediated glomerulonephritis.
Mesnard L, Rafat C, Vandermeersch S, Hertig A, Cathelin D, Xu-Dubois YC, Jouanneau C, Keller AC, Ribeil JA, Leite-de-Moraes MC, Rondeau E, FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Oct 25 10 3543-53 -
Downregulation of basophil-derived IL-4 and in vivo T(H)2 IgE responses by serotonin and other organic cation transporter 3 ligands.
Schneider E, Machavoine F, Bricard-Rignault R, Levasseur M, Petit-Bertron AF, Gautron S, Ribeil JA, Launay JM, Mecheri S, Côté F, Dy M, The Journal of allergy and clinical immunology 2011 Oct 128 4 864-871.e2 -
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia.
Coulon S, Dussiot M, Grapton D, Maciel TT, Wang PH, Callens C, Tiwari MK, Agarwal S, Fricot A, Vandekerckhove J, Tamouza H, Zermati Y, Ribeil JA, Djedaini K, Oruc Z, Pascal V, Courtois G, Arnulf B, Alyanakian MA, Mayeux P, Leanderson T, Benhamou M, Cogné M, Monteiro RC, Hermine O, Moura IC, Nature medicine 2011 Oct 17 11 1456-65 -
First experience of autologous peripheral blood stem cell mobilization with biosimilar granulocyte colony-stimulating factor.
Lefrère F, Brignier AC, Elie C, Ribeil JA, Bernimoulin M, Aoun C, Dal Cortivo L, Delarue R, Hermine O, Cavazzana-Calvo M, Advances in therapy 2011 Apr 28 4 304-10 -
Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling.
Gabet AS, Coulon S, Fricot A, Vandekerckhove J, Chang Y, Ribeil JA, Lordier L, Zermati Y, Asnafi V, Belaid Z, Debili N, Vainchenker W, Varet B, Hermine O, Courtois G, Cell death and differentiation 2011 Apr 18 4 678-89 -
Proliferating cell nuclear antigen acts as a cytoplasmic platform controlling human neutrophil survival.
Witko-Sarsat V, Mocek J, Bouayad D, Tamassia N, Ribeil JA, Candalh C, Davezac N, Reuter N, Mouthon L, Hermine O, Pederzoli-Ribeil M, Cassatella MA, The Journal of experimental medicine 2010 Nov 207 12 2631-45 -
HSP27 controls GATA-1 protein level during erythroid cell differentiation.
de Thonel A, Vandekerckhove J, Lanneau D, Selvakumar S, Courtois G, Hazoume A, Brunet M, Maurel S, Hammann A, Ribeil JA, Zermati Y, Gabet AS, Boyes J, Solary E, Hermine O, Garrido C, Blood 2010 Jul 116 1 85-96 -
Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia.
Callens C, Coulon S, Naudin J, Radford-Weiss I, Boissel N, Raffoux E, Wang PH, Agarwal S, Tamouza H, Paubelle E, Asnafi V, Ribeil JA, Dessen P, Canioni D, Chandesris O, Rubio MT, Beaumont C, Benhamou M, Dombret H, Macintyre E, Monteiro RC, Moura IC, Hermine O, The Journal of experimental medicine 2010 Apr 207 4 731-50 -
[Anemia in adult sickle cell disease].
Arlet JB, Bartolucci P, Habibi A, Ribeil JA, Stankovic K, Lionnet F, La Revue de medecine interne 2009 Dec 30 Suppl 4 S319-22 -
Fanconi syndrome due to deferasirox.
Rafat C, Fakhouri F, Ribeil JA, Delarue R, Le Quintrec M, American journal of kidney diseases : the official journal of the National Kidney Foundation 2009 Nov 54 5 931-4 -
[Guidelines for management of adult sickle cell disease].
Lionnet F, Arlet JB, Bartolucci P, Habibi A, Ribeil JA, Stankovic K, La Revue de medecine interne 2009 Sep 30 Suppl 3 S162-223 -
Selective reduction of JAK2V617F-dependent cell growth by siRNA/shRNA and its reversal by cytokines.
Jedidi A, Marty C, Oligo C, Jeanson-Leh L, Ribeil JA, Casadevall N, Galy A, Vainchenker W, Villeval JL, Blood 2009 Aug 114 9 1842-51 -
Serum-free culture medium and IL-7 costimulation increase the sensitivity of ELISpot detection.
Martinuzzi E, Scotto M, Enée E, Brezar V, Ribeil JA, van Endert P, Mallone R, Journal of immunological methods 2008 Apr 333 1-2 61-70 -
[Hsp 70, guardian angel of GATA-1 during erythroid differentiation].
Vandekerckhove J, Ribeil JA, Zermati Y, Garrido C, Courtois G, Solary E, Hermine O, Medecine sciences : M/S 2008 Jan 24 1 37-40 -
Evaluation of an algorithm based on peripheral blood hematopoietic progenitor cell and CD34+ cell concentrations to optimize peripheral blood progenitor cell collection by apheresis.
Lefrère F, Zohar S, Beaudier S, Audat F, Ribeil JA, Ghez D, Varet B, Cavazzana-Calvo M, Dal Cortivo L, Letestu R, McIntyre E, Brouzes C, Transfusion 2007 Oct 47 10 1851-7 -
Decreased transfusion needs associated with hydroxyurea therapy in Algerian patients with thalassemia major or intermedia.
Bradai M, Pissard S, Abad MT, Dechartres A, Ribeil JA, Landais P, de Montalembert M, Transfusion 2007 Oct 47 10 1830-6 -
Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1.
Ribeil JA, Zermati Y, Vandekerckhove J, Cathelin S, Kersual J, Dussiot M, Coulon S, Moura IC, Zeuner A, Kirkegaard-Sørensen T, Varet B, Solary E, Garrido C, Hermine O, Nature 2007 Jan 445 7123 102-5 -
Overexpression of the heat-shock protein 70 is associated to imatinib resistance in chronic myeloid leukemia.
Pocaly M, Lagarde V, Etienne G, Ribeil JA, Claverol S, Bonneu M, Moreau-Gaudry F, Guyonnet-Duperat V, Hermine O, Melo JV, Dupouy M, Turcq B, Mahon FX, Pasquet JM, Leukemia 2007 Jan 21 1 93-101 -
CD34 stem cell top-ups without conditioning after initial haematopoietic stem cell transplantation for correction of incomplete haematopoietic and immunological recovery in severe congenital immunodeficiencies.
Booth C, Ribeil JA, Audat F, Dal-Cortivo L, Veys PA, Thrasher AJ, Davies EG, Lefrère F, Fischer A, Cavazzana-Calvo M, Gaspar HB, British journal of haematology 2006 Nov 135 4 533-7 -
The VAD chemotherapy regimen plus a G-CSF dose of 10 microg/kg is as effective and less toxic than high-dose cyclophosphamide plus a G-CSF dose of 5 microg/kg for progenitor cell mobilization: results from a monocentric study of 82 patients.
Lefrère F, Zohar S, Ghez D, Delarue R, Audat F, Suarez F, Hermine O, Damaj G, Maillard N, Ribeil JA, Azagury M, Misbahi R, Jondeau K, Cavazzana-Calvo M, Dal Cortivo L, Varet B, Bone marrow transplantation 2006 Apr 37 8 725-9 -
[Erythropoiesis: a paradigm for the role of caspases in cell death and differentiation].
Ribeil JA, Zermati Y, Vandekerckhove J, Dussiot M, Kersual J, Hermine O, Journal de la Societe de biologie 2005 199 3 219-31 -
[Cerebral glioblastoma complicating the course of myeloma].
Gisserot O, de Jaureguiberry JP, Ribeil JA, Villemagne B, Jaubert D, Presse medicale (Paris, France : 1983) 1997 Sep 26 25 1197 -
[Meningeal tumor].
Galzin M, de Jaureguiberry JP, Ribeil JA, Pujol A, Lescout JM, Calvet A, Billant JB, Jaubert D, La Revue de medecine interne 1997 18 11 906-7
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Selective AMPKβ1 activation induces fetal hemoglobin in human erythroid cells and sickle cell mice via the noncanonical NRF2 pathway.
Research
- Translational research for hemoglobinopathies such as sickle cell disease and thalassemia
- The development of gene therapy for hemoglobinopathies
Clinical Focus
- Hematology
- Red Blood Cell Disorders
- Sickle Cell Disease
- Thalassemia