Jeffrey Cadeddu, M.D.

Jeffrey Cadeddu, M.D.

  • Ralph C. Smith, M.D., Distinguished Chair in Minimally Invasive Urologic Surgery
  • Urology
  • Kidney Cancer
  • Genitourinary Surgery


Jeffrey Cadeddu, M.D., is one of Texas’ leading urologists in the surgical treatment of prostate and kidney disorders. As Director of the UT Southwestern Clinical Center for Minimally Invasive Treatment of Urologic Cancer, he has performed more than 500 robotic/laparoscopic procedures on the prostate and introduced a number of firsts in the minimally invasive surgical treatment of kidney cancer and kidney disease.

His training and extensive experience with kidney cancers in particular allow him to offer patients the full gamut of options in managing the disease without losing the kidney. Those options include ablation, an outpatient procedure in which the tumor is destroyed with a heated probe, rather than removed surgically. Dr. Cadeddu was the first in Texas to perform the procedure. He also has the most experience in North Texas with laparoscopic and robotic partial nephrectomy to remove kidney cancers.

Along with an active clinical practice focused on minimally invasive procedures, Dr. Cadeddu maintains a robust research program aimed at developing new technologies and techniques that will make kidney surgery even less invasive while also maximizing kidney function better than what has traditionally been done.

Dr. Cadeddu joined the faculty of UT Southwestern Medical Center, where he is a Professor of Urology and Radiology, in 1999 after receiving his initial medical training and completing residencies in urology and surgery at Johns Hopkins School of Medicine in Baltimore. 

As an expert in the treatment of kidney and prostate diseases, Dr. Cadeddu regularly lectures and educates other medical professionals on the latest developments in managing urologic conditions. In 2007, he received the Gold Cystoscope Award from the American Urological Association for his contributions to advances in kidney cancer treatment and the training of numerous academic urologists. 

In 2018, he was included in D Magazine's Best Doctors list and was named a Texas Monthly Super Doctor.

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Meet Dr. Cadeddu

Dallas Urologist and Pioneering Laparoscopic Surgeon

When Jeffrey Cadeddu, M.D., was recruited to UT Southwestern Medical Center in 1999, he came because he thought it would be a good place to practice medicine and offer opportunities to do groundbreaking work in the field of urology. He hasn’t been disappointed, nor have his patients, who have gained access to leading-edge procedures pioneered by Dr. Cadeddu.

"We’re not resting on our laurels. We’re continuing to develop new technologies and new techniques. My goal is to continue to push the envelope.”

A recognized expert in laparoscopic and robotic surgery, Dr. Cadeddu was the first surgeon in the U.S. to successfully remove a patient’s kidney through the belly button, reducing both scarring and recovery time; the first in North Texas to repair a malfunctioning kidney laparoscopically through the belly button; the first in North Texas to perform laparoscopic prostatectomy for prostate cancer; and the first in Texas to destroy kidney tumors by burning them – known as radiofrequency ablation – rather than removing them through surgery.

“I do a lot of research in novel technologies for treating patients with kidney problems and kidney cancer,” he says.

With 20 years’ experience as a urologist, Dr. Cadeddu treats both kidney and prostate conditions. “The kidney and the prostate are the two most complex, challenging operations we do, but both are particularly amenable to minimally invasive techniques,” he says. “With the kidney, the difference between minimally invasive and regular surgery is three to four less days in the hospital and a month to a month-and-a-half quicker recovery.”

Developing groundbreaking techniques and producing good outcomes and quicker recoveries keep Dr. Cadeddu at the forefront of his field. But, he says, it’s grateful patients who ultimately are the source of his greatest satisfaction.

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Education & Training
  • Medical School - Johns Hopkins University (1989-1993)
  • Internship - Johns Hopkins School of Medicine (1993-1994), General Surgery
  • Residency - Johns Hopkins School of Medicine (1994-1995), General Surgery
  • Residency - Johns Hopkins School of Medicine (1995-1998), Urology
Professional Associations & Affiliations
  • American Urological Association
  • Endourological Society
  • Society for Urologic Oncology
Honors & Awards
  • Texas Super Doctors, Urology 2012
  • Gold Cystoscope Award 2007, For Significant Contributions to the Field of Urology within 10 Years of Residency
  • Ralph C. Smith, MD, Distinguished Chair in Minimally Invasive Urologic Surgery 2006
  • Alpha Omega National Medical Honor Society 1998, The Johns Hopkins University School of Medicine
  • Best Doctors in Dallas, 2007 - 2012
Books & Publications
  • Surgical Education
  • Prostate Cancer
  • Laparoscopic Techniques
  • Kidney Cancer

Clinical Focus

  • Kidney Cancer
  • Genitourinary Surgery
  • Genitourinary Cancer
  • Prostate Cancer
  • Testicular Cancer
  • Stones

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Q&A by Dr. Cadeddu

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Urology Clinic

at West Campus Building 3 2001 Inwood Road, 4th Floor
Dallas, Texas 75390
214-645-8765 Directions Parking Info