John Beckham, M.D.

John Beckham, M.D.

  • Jay P. Sanford Professorship in Infectious Diseases
  • Internal Medicine - Infectious Diseases and Geographic Medicine
  • General Infectious Diseases
  • Neurological Infections

Appointment New Patient Appointment or 214-645-2800

Appointment New Patient Appointment or 214-645-2800

Biography

John Beckham, M.D., is a Professor in the Department of Internal Medicine and Chief of the Division of Infectious Diseases & Geographic Medicine at UT Southwestern Medical Center. He specializes in general infectious diseases, neurological infections, and human immunodeficiency virus (HIV).

Dr. Beckham earned his medical degree and completed a residency in internal medicine at Baylor College of Medicine. He completed a clinical fellowship in infectious disease and postdoctoral research training in neurovirology at the University of Colorado School of Medicine.

Board certified in internal medicine and infectious disease, he joined the UT Southwestern faculty in 2023.

Dr. Beckham is a Fellow of the American College of Physicians and the Infectious Diseases Society of America. He is also a member of the American Society for Virology, the American Society for Microbiology, the American Association for the Advancement of Science, the American Association of Immunologists, and the American Society of Tropical Medicine and Hygiene.

His laboratory studies the virology and vaccine approaches associated with emerging RNA viruses, as well as the unique immune responses in the brain that prevent infections but may also contribute to neurodegenerative diseases such as Parkinson’s disease.

A prolific writer and lecturer, Dr. Beckham has contributed to 11 books and published numerous academic articles related to his areas of expertise. He serves on the editorial board of Journal of Neuroimmunology, as an ad hoc reviewer for several scholarly journals, and as a member of several National Institutes of Health grant review committees.

Personal Note

When he is not at work, Dr. Beckham enjoys running, biking, hiking, and mountain climbing.

Education & Training
  • Medical School - Baylor College of Medicine (1997-2001)
  • Fellowship - University of Colorado School of Medicine (2004-2007), Infectious Diseases
  • Residency - Baylor College of Medicine (2001-2004), Internal Medicine
Professional Associations & Affiliations
  • American Association for the Advancement of Science
  • American Association of Immunologists
  • American Society for Clinical Investigation
  • American Society for Microbiology
  • American Society for Virology
  • American Society of Tropical Medicine and Hygiene
  • Infectious Diseases Society of America
Honors & Awards
  • Merit Scholar 2017-2023, Veterans Affairs
  • Young Practitioner Award 2008, American Society for Clinical Investigation
  • Career Development Award 2007, Veterans Affairs
  • Medical Virology Club Award 2008, American Society for Virology
  • Research Grant 2000, American Cancer Society
Books & Publications
  • Books
    • Viral encephalitis in Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases (10th ed.)
      Beckham JD, Tyler KL (2023, In Press), Philadelphia, PA, Elsevier Churchill Livingstone
    • Arboviruses causing fever, rash, and neurologic syndromes in Goldman-Cecil Medicine (27th ed.)
      Beckham JD (2022)
    • Infections of the nervous system in Bradley and Daroff’s Neurology in Clinical Practice (8th ed.)
      Beckham JD, Solbrig MV, Tyler KL (2020), Elsevier
    • Neurologic manifestations of West Nile virus disease in Clinical Neurovirology (2nd ed.)
      Smith DE, Beckham JD, Pastula DM, Tyler KL (2019), Boca Raton, FL, CRC Press
    • Arbovirus dermatology in Fitzpatrick’s Dermatology
      Asturias E, Beckham JD (2018), New York, NY, McGraw Hill Medical
    • Infections and inflammatory disorders in Practical Surgical Neuropathology
      Kleinschmidt-DeMasters BK, Beckham JD, Tyler KL (2018), Amsterdam, Netherlands, Elsevier
    • West Nile virus and St. Louis virus encephalitis in Handbook of Clinical Neurology
      Oyer R, Beckham JD, Tyler KL (2014), Amsterdam, Netherlands, Elsevier B.V.
    • Viral myelitis in Infections of the Central Nervous System (4th ed.)
      Beckham JD, Tyler KL (2014), Philadelphia, PA, LWW
    • Infections of the nervous system in Neurology in Clinical Practice (6th ed.)
      Beckham JD, Solbrig MV, Tyler KL (2012), Amsterdam, Netherlands, Elsevier
    • Viral encephalitis in Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases (7th-9th eds.)
      Beckham JD, Tyler KL (2009. Revised 2022), Philadelphia, PA, Elsevier Churchill Livingstone
    • Clinical manifestations of neurological disease in West Nile Encephalitis Virus Infection: Viral Pathogenesis and the Host Immune Response
      Beckham JD, Tyler KL (2008), New York, NY, Springer Publishers
  • Publications
    • Brain Abscesses in the Tropics
      Corbisiero MF, Ripperton RA, Creighton EG, Smyth AM, Beckham JD, Henao-Martínez AF Current Tropical Medicine Reports 2023 Dec 10 235-243
    • A functional role for alpha-synuclein in neuroimmune responses
      Heiden DL, Monogue B, Ali MD, Beckham JD Journal of Neuroimmunology 2023 Mar 376
    • Severely ill and high-risk COVID-19 patients exhibit increased peripheral circulation of CD62L+ and perforin+ T cells
      Lesteberg KE, Araya P, Waugh KA, Chauhan L, Espinosa JM, Beckham JD Frontiers in immunology 2023 Feb 14
    • Activation and pro-inflammatory cytokine production by unswitched memory B cells during SARS-CoV-2 infection
      Castleman MJ, Santos AL, Lesteberg KE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM Frontiers in immunology 2023 14
    • Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19 (Scientific Reports, (2022), 12, 1, (5207), 10.1038/s41598-022-09133-9)
      Bai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan ED Scientific reports 2022 Dec 12
    • Nervous System Manifestations of Arboviral Infections
      Chauhan L, Matthews E, Piquet AL, Henao-Martinez A, Franco-Paredes C, Tyler KL, Beckham D, Pastula DM Current Tropical Medicine Reports 2022 Dec 9 107-118
    • Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19
      Bai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan ED Scientific reports 2022 Dec 12
    • Clinical and Economic Impact of COVID-19 on Agricultural Workers, Guatemala1
      Olson D, Calvimontes DM, Lamb MM, Guzman G, Barrios E, Chacon A, Rojop N, Arias K, Gomez M, Bolanos GA, Monzon J, Chard AN, Iwamoto C, Duca LM, Vuong N, Fineman M, Lesteberg K, Beckham D, Santiago ML, Quicke K, Ebel G, Gutierrez EZ, Azziz-Baumgartner E, Hayden FG, Mansour H, Edwards K, Newman LS, Asturias EJ Emerging Infectious Diseases 2022 Dec 28 S277-S287
    • Alpha-synuclein supports type 1 interferon signalling in neurons and brain tissue
      Monogue B, Chen Y, Sparks H, Behbehani R, Chai A, Rajic AJ, Massey A, Kleinschmidt-Demasters BK, Vermeren M, Kunath T, Beckham JD Brain 2022 Oct 145 3622-3636
    • Neurology of Acute Viral Infections
      Krett JD, Beckham JD, Tyler KL, Piquet AL, Chauhan L, Wallace CJ, Pastula DM, Kapadia RK The Neurohospitalist 2022 Oct 12 632-646
    • Herpesvirus-Associated Encephalitis: an Update
      Matthews E, Beckham JD, Piquet AL, Tyler KL, Chauhan L, Pastula DM Current Tropical Medicine Reports 2022 Sep 9 92-100
    • Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells
      Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM Frontiers in immunology 2022 Sep 13
    • High SARS-CoV-2 Seroprevalence and Rapid Neutralizing Antibody Decline among Agricultural Workers in Rural Guatemala, June 2020–March 2021
      Iwamoto C, Lesteberg KE, Lamb MM, Calvimontes DM, Guo K, Barrett BS, Mickens KL, Duca LM, Monzon J, Chard AN, Guzman G, Barrios E, Rojop N, Arias K, Gomez M, Paiz C, Bolanos GA, Edwards KM, Zielinski Gutierrez E, Azziz-Baumgartner E, Asturias EJ, Santiago ML, Beckham JD, Olson D Vaccines 2022 Jul 10
    • A Multicenter, Prospective, Observational, Cohort-Controlled Study of Clinical Outcomes Following Coronavirus Disease 2019 (COVID-19) Convalescent Plasma Therapy in Hospitalized Patients with COVID-19
      Chauhan L, Pattee J, Ford J, Thomas C, Lesteberg K, Richards E, Bernas CA, Loi M, Dumont L, Annen K, Berg M, Zirbes M, Knight V, Miller A, Jenkins TC, Bennett TD, Monkowski D, Boxer RS, Beckham JD Clinical Infectious Diseases 2022 Jul 75 E466-E472
    • SARS-CoV-2 infection relaxes peripheral B cell tolerance
      Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, David Beckham J, Pelanda R, Torres RM Journal of Experimental Medicine 2022 Jun 219
    • Two Cases of Monkeypox-Associated Encephalomyelitis — Colorado and the District of Columbia, July–August 2022
      Pastula DM, Copeland MJ, Hannan MC, Rapaka S, Kitani T, Kleiner E, Showler A, Yuen C, Ferriman EM, House J, O’Brien S, Burakoff A, Gupta B, Money KM, Matthews E, Beckham JD, Chauhan L, Piquet AL, Kumar RN, Tornatore CS, Padgett K, O’Laughlin K, Mangla AT, Kumar PN, Tyler KL, O’Connor SM Morbidity and Mortality Weekly Report 2022 71 1212-1215
    • Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication
      Akiyama BM, Graham ME, O′donoghue Z, Beckham JD, Kieft JS Nucleic acids research 2021 Jul 49 7122-7138
    • Arboviral central nervous system infections
      Schultz JS, Sparks H, Beckham JD Current Opinion in Infectious Diseases 2021 Jun 34 264-271
    • Infections, immunodeficiency, and complications of immunomodulatory therapies in neuroimmunology
      Piquet AL, Pastula DM, Beckham JD, Tyler KL 2021 Apr 405-415
    • Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19
      Bai X, Hippensteel J, Leavitt A, Maloney JP, Beckham D, Garcia C, Li Q, Freed BM, Ordway D, Sandhaus RA, Chan ED Medical Hypotheses 2021 Jan 146
    • Pregnancy alters innate and adaptive immune responses to zika virus infection in the reproductive tract
      Lesteberg KE, Fader DS, David Beckham J Journal of Immunology 2020 Dec 205 3107-3121
    • Is COVID-19 a Perfect Storm for Parkinson's Disease?
      Brundin P, Nath A, Beckham JD Trends in Neurosciences 2020 Dec 43 931-933
    • Disruption of zika virus xrRNA1-dependent sfRNA1 production results in tissue-specific attenuated viral replication
      Sparks H, Monogue B, Akiyama B, Kieft J, David Beckham J Viruses 2020 Oct 12
    • Global perspectives on arbovirus outbreaks: a 2020 snapshot
      Kading RC, Brault AC, Beckham JD Tropical Medicine and Infectious Disease 2020 Sep 5
    • Usutu virus disease: a potential problem for North America?
      Gill CM, Kapadia RK, Beckham JD, Piquet AL, Tyler KL, Pastula DM Journal of NeuroVirology 2020 Apr 26 149-154
    • The struggling infectious diseases fellow: Remediation challenges and opportunities
      Melia MT, Paez A, Reid G, Chirch LM, Luther VP, Blackburn BG, Perez F, Abdoler E, Kaul DR, Rehm S, Harik N, Barsoumian A, Person AK, Yun H, David Beckham J, Boruchoff S, Cariello PF, Cutrell JB, Graber CJ, Lee DH, Maziarz E, Paras ML, Razonable RR, Ressner R, Chen A, Chow B, Escota G, Herc E, Johnson A, Maves RC, Nnedu O, Clauss H, Kulkarni P, Pottinger PS, Serpa JA, Bhowmick T, Bittner M, Wooten D, Casanas B, Shnekendorf R, Blumberg EA Open Forum Infectious Diseases 2020 Mar 7
    • An Overview of Powassan Virus Disease
      Khan M, Beckham JD, Piquet AL, Tyler KL, Pastula DM The Neurohospitalist 2019 Oct 9 181-182
    • Infectious causes and outcomes in patients presenting with cerebral spinal fluid pleocytosis
      Brown BL, Fidell A, Ingolia G, Murad E, Beckham JD Journal of NeuroVirology 2019 Aug 25 448-456
    • Immunology of West Nile Virus Infection and the Role of Alpha-Synuclein as a Viral Restriction Factor
      Lesteberg KE, Beckham JD Viral Immunology 2019 Jan 32 38-47
    • Five Emerging Neuroinvasive Arboviral Diseases: Cache Valley, Eastern Equine Encephalitis, Jamestown Canyon, Powassan, and Usutu
      Gill CM, Beckham JD, Piquet AL, Tyler KL, Pastula DM Seminars in Neurology 2019 39 419-427
    • Defining diagnostic approaches and outcomes in patients with inflammatory CSF: A retrospective cohort study
      Brown B, Fidell A, Ingolia G, Murad E, Beckham JD Clinical Neurology and Neurosurgery 2018 Sep 172 105-111
    • Cryptococcosis and cryptococcal meningitis: New predictors and clinical outcomes at a United States academic medical centre
      Kashef Hamadani BH, Franco-Paredes C, McCollister B, Shapiro L, Beckham JD, Henao-Martínez AF Mycoses 2018 May 61 314-320
    • 23 - Infections and Inflammatory Disorders
      Kleinschmidt-DeMasters BK, Beckham JD, Tyler KL 2018 547-579
    • Molecular mechanisms of neuroinflammation and injury during acute viral encephalitis
      Shives KD, Tyler KL, Beckham JD Journal of Neuroimmunology 2017 Jul 308 102-111
    • Zika Virus Disease for the Neurointensivist
      Pastula DM, Durrant JC, Smith DE, Beckham JD, Tyler KL Neurocritical Care 2017 Jun 26 457-463
    • Zika virus, a novel mosquito-borne congenital virus infection
      Beckham JD Journal of NeuroVirology 2017 Jun 23 339-340
    • Zika Virus Disease and Associated Neurologic Complications
      Duca LM, Beckham JD, Tyler KL, Pastula DM Current Infectious Disease Reports 2017 Jan 19
    • Zika virus disease for neurologists
      Smith DE, Beckham JD, Tyler KL, Pastula DM Neurology: Clinical Practice 2016 Dec 6 515-522
    • Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease
      Akiyama BM, Laurence HM, Massey AR, Costantino DA, Xie X, Yang Y, Shi PY, Nix JC, Beckham JD, Kieft JS Science 2016 Dec 354 1148-1152
    • Risk Factors for Cryptococcal Meningitis: A Single United States Center Experience
      Henao-Martínez AF, Gross L, Mcnair B, McCollister B, DeSanto K, Montoya JG, Shapiro L, Beckham JD Mycopathologia 2016 Dec 181 807-814
    • Alpha-synuclein, a novel viral restriction factor hiding in plain sight
      Massey AR, Beckham JD DNA and Cell Biology 2016 Nov 35 643-645
    • Zika virus: An emergent neuropathological agent
      White MK, Wollebo HS, David Beckham J, Tyler KL, Khalili K Annals of Neurology 2016 Oct 80 479-489
    • 4EBP-dependent signaling supports west nile virus growth and protein expression
      Shives KD, Massey AR, May NA, Morrison TE, Beckham JD Viruses 2016 Oct 8
    • Zika virus as an emerging global pathogen: Neurological complications of zika virus
      Beckham JD, Pastula DM, Massey A, Tyler KL JAMA neurology 2016 Jul 73 875-879
    • Four emerging arboviral diseases in North America: Jamestown Canyon, Powassan, chikungunya, and Zika virus diseases
      Pastula DM, Smith DE, Beckham JD, Tyler KL Journal of NeuroVirology 2016 Jun 22 257-260
    • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
      Klionsky DJ, Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Aguirre-Ghiso J, Airoldi EM, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Bianchi MW, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San-Pedro JM, Bravosan-Pedro JM, Bravosan-Pedro JM, Bravosan-Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bulavin DV, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cecconi F, Cecconi F, Cederbaum AI, Ceña V, Ceña V, Cenci S, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chiariello M, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi EK, Choi EK, Choi EK, Choi J, Choi ME, Choi SI, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Claerhout S, Clague MJ, Clària J, Clarke PG, Clarke R, Clementi E, Clementi E, Cleyrat C, Cnop M, Coccia EM, Cocco T, Codogno P, Coers J, Cohen EE, Colecchia D, Colecchia D, Colecchia D, Coletto L, Coll NS, Colucci-Guyon E, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corral-Ramos C, Corti O, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Cottet S, Couve E, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Crespo JL, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, Dahmen U, Dai C, Dai W, Dai Y, Dalby KN, Valle LD, Dalmasso G, D'amelio M, Damme M, Darfeuille-Michaud A, Dargemont C, Darley-Usmar VM, Dasarathy S, Dasgupta B, Dash S, Dass CR, Davey HM, Davids LM, Dávila D, Davis RJ, Dawson TM, Dawson TM, Dawson VL, Daza P, de Belleroche J, de Figueiredo P, de Figueiredo P, de Figueiredo RC, de la Fuente J, De Martino L, De Matteis A, De Meyer GR, De Milito A, De Santi M, de Souza W, De Tata V, De Zio D, Debnath J, Dechant R, Decuypere JP, Decuypere JP, Deegan S, Dehay B, Del Bello B, Del Re DP, Delage-Mourroux R, Delbridge LM, Deldicque L, Delorme-Axford E, Deng Y, Dengjel J, Denizot M, Dent P, Der CJ, Deretic V, Derrien B, Deutsch E, Devarenne TP, Devenish RJ, Di Bartolomeo S, Di Daniele N, Di Domenico F, Di Nardo A, Di Paola S, Di Pietro A, Di Renzo L, Di Antonio A, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dickey CA, Dickson RC, Diederich M, Digard P, Dikic I, Dinesh-Kumar SP, Ding C, Ding WX, Ding Z, Dini L, Distler JH, Diwan A, Djavaheri-Mergny M, Dmytruk K, Dobson RC, Doetsch V, Dokladny K, Dokudovskaya S, Donadelli M, Dong XC, Dong X, Dong Z, Donohue TM, Donohue-Jr TM, Doran KS, D'orazi G, Dorn GW, Dosenko V, Dridi S, Drucker L, Du J, Du LL, Du L, du Toit A, Dua P, Duan L, Duann P, Dubey VK, Duchen MR, Duchosal MA, Duez H, Dugail I, Dumit VI, Duncan MC, Dunlop EA, Dunn WA, Dupont N, Dupuis L, Dupuis L, Durán RV, Durcan TM, Duvezin-Caubet S, Duvvuri U, Eapen V, Ebrahimi-Fakhari D, Echard A, Eckhart L, Edelstein CL, Edinger AL, Eichinger L, Eisenberg T, Eisenberg-Lerner A, Eissa NT, El-Deiry WS, El-Khoury V, Elazar Z, Eldar-Finkelman H, Elliott CJ, Emanuele E, Emmenegger U, Engedal N, Engelbrecht AM, Engelender S, Enserink JM, Erdmann R, Erenpreisa J, Eri R, Eriksen JL, Erman A, Escalante R, Eskelinen EL, Espert L, Esteban-Martínez L, Evans TJ, Fabri M, Fabrias G, Fabrizi C, Facchiano A, Færgeman NJ, Faggioni A, Fairlie WD, Fairlie WD, Fairlie WD, Fan C, Fan D, Fan J, Fang S, Fanto M, Fanzani A, Farkas T, Faure M, Favier FB, Favier FB, Fearnhead H, Federici M, Fei E, Felizardo TC, Feng H, Feng Y, Feng Y, Feng Y, Ferguson TA, Fernández ÁF, Fernandez-Barrena MG, Fernandez-Checa JC, Fernandez-Checa JC, Fernández-López A, Fernandez-Zapico ME, Feron O, Ferraro E, Ferreira-Halder CV, Fesus L, Feuer R, Fiesel FC, Filippi-Chiela EC, Filomeni G, Filomeni G, Fimia GM, Fimia GM, Fingert JH, Fingert JH, Finkbeiner S, Finkbeiner S, Finkel T, Fiorito F, Fiorito F, Fisher PB, Flajolet M, Flamigni F, Florey O, Florio S, Floto RA, Folini M, Follo C, Fon EA, Fornai F, Fornai F, Fortunato F, Fraldi A, Franco R, Francois A, Francois A, François A, Frankel LB, Fraser ID, Frey N, Freyssenet DG, Frezza C, Friedman SL, Frigo DE, Frigo DE, Fu D, Fuentes JM, Fueyo J, Fujitani Y, Fujiwara Y, Fujiya M, Fukuda M, Fulda S, Fusco C, Gabryel B, Gaestel M, Gailly P, Gajewska M, Galadari S, Galadari S, Galili G, Galindo I, Galindo MF, Galliciotti G, Galluzzi L, Galluzzi L, Galluzzi L, Galluzzi L, Galluzzi L, Galy V, Gammoh N, Gandy S, Gandy S, Ganesan AK, Ganesan S, Ganley IG, Gannagé M, Gao FB, Gao F, Gao JX, Nannig LG, Véscovi EG, Garcia-Macía M, Garcia-Ruiz C, Garg AD, Garg PK, Gargini R, Gassen NC, Gatica D, Gatica D, Gatti E, Gatti E, Gatti E, Gavard J, Gavathiotis E, Ge L, Ge P, Ge S, Gean PW, Gelmetti V, Genazzani AA, Geng J, Genschik P, Gerner L, Gestwicki JE, Gewirtz DA, Ghavami S, Ghigo E, Ghosh D, Giammarioli AM, Giammarioli AM, Giampieri F, Giampietri C, Giatromanolaki A, Gibbings DJ, Gibellini L, Gibson SB, Ginet V, Giordano A, Giordano A, Giorgini F, Giovannetti E, Giovannetti E, Girardin SE, Gispert S, Giuliano S, Giuliano S, Gladson CL, Glavic A, Gleave M, Godefroy N, Gogal RM, Gokulan K, Goldman GH, Goletti D, Goligorsky MS, Gomes AV, Gomes LC, Gomez H, Gomez-Manzano C, Gómez-Sánchez R, Gonçalves DA, Goncu E, Gong Q, 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    • Arbovirus Infections
      Beckham JD, Tyler KL CONTINUUM Lifelong Learning in Neurology 2015 Dec 21 1599-1611
    • West Nile virus encephalitis 16 years later
      Kleinschmidt-DeMasters BK, Beckham JD Brain Pathology 2015 Sep 25 625-633
    • Cryptococcosis in solid organ transplant recipients
      Henao-Martínez AF, Beckham JD Current Opinion in Infectious Diseases 2015 Aug 28 300-307
    • Encephalitis
      Beckham JD, Tyler KL 2014 Aug 1 1144-1163
    • Acute viral myelitis
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    • Microbial exposure alters HIV-1-induced mucosal CD4+ T cell death pathways Ex vivo
      Steele AK, Lee EJ, Manuzak JA, Dillon SM, Beckham JD, McCarter MD, Santiago ML, Wilson CC Retrovirology 2014 Feb 11
    • Death receptor-mediated apoptotic signaling is activated in the brain following infection with west nile virus in the absence of a peripheral immune response
      Clarke P, Leser JS, Quick ED, Dionne KR, Beckham JD, Tyler KL Journal of virology 2014 Jan 88 1080-1089
    • West Nile and St. Louis encephalitis viruses
      Oyer RJ, Beckham JD, Tyler KL 2014 433-447
    • West Nile virus-induced activation of mammalian target of rapamycin complex 1 supports viral growth and viral protein expression
      Shives KD, Beatman EL, Chamanian M, O'Brien C, Hobson-Peters J, Beckham JD Journal of virology 2014 88 9458-9471
    • Elevated CSF cytokines in the jarisch-herxheimer reaction of general paresis
      Davis LE, Oyer R, Beckham JD, Tyler KL JAMA neurology 2013 Aug 70 1060-1064
    • West Nile virus growth is independent of autophagy activation
      Beatman E, Oyer R, Shives KD, Hedman K, Brault AC, Tyler KL, David Beckham J Virology 2012 Nov 433 262-272
    • Neuro-Intensive Care of Patients with Acute CNS Infections
      Beckham JD, Tyler KL Neurotherapeutics 2012 Jan 9 124-138
    • Our thanks to reviewers in 2011
      Ault KA, Balon R, Barber K, Basha M, Becker P, Beckham JD, Bharath S, Blereau RP, Brady WJ, Bryan CS, Buckley RM, Calianno C, Caplan LS, Cardarelli R, Carnethon MR, Chancellor MB, Cherner R, Connolly JF, Costanza ME, Cummings JL, Effron D, Enam SA, Fareed J, Farmer RG, Fitzgerald FT, Frank P, Garr DR, Ghaemi SN, Gleich P, Glendenning C, Golestaneh L, Grin CM, Hagensee ME, Hallett R, Harmon GS, Harrigan R, Heffron WA, Herrera JL, Holroyd S, Hopp RJ, Huffman GB, Huneycutt B, Iliffe S, Ilowite JS, Ismail MS, Jain M, Jhaveri KD, Jones M, Kamat DM, Kaplan DL, Kaplan LI, Kirchner JT, Kramer HM, Lanspa SJ, Leach RE, Lerma EV, Leung AK, Levine DP, Lieberman JA, Louie S, Maddox DE, Mandell BF, Mathys M, McBride BF, McCarron R, McConnell RY, Mopala PR, Mosby J, Murphy DP, Nelson A, Nash DB, Nash DT, Papernik M, Parthemore JG, Petty TL, Picco MF, Pollart SM, Pregerson DB, Prisant LM, Rakel RE, Ramesh S, Reisman RE, Reynolds W, Rice D, Rinkevich D, Robinson WD, Rogers RJ, Rosen T, Roth M, Rothe MJ, Rubin RN, Rutecki GW, Schmidt JD, Segraves RT, Self TH, Shahady EJ, Skorin L, Smith C, Smith C, Snell C, Sofair AN, Someshwar J, Stitik TP, Strauss MB, Sulavik SB, Touchet N, Trimble EL, Urban RJ, Vella A, Vidt DG, Volochayev R, Weaver EM, Weisman MH, Weiss S, White H, White RD, Willerson JT, Wolfson RJ, Yaakob W, Yaffe K, Yawn BP, Yellumahanthi DK, Zimmer RJ, Zimmerman D, Zonszein J Consultant 2011 Dec 51 872
    • A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition
      Dionne KR, Leser JS, Lorenzen KA, Beckham JD, Tyler KL Experimental Neurology 2011 Apr 228 222-231
    • Caspase-3 activation is required for reovirus-induced encephalitis in vivo
      Beckham JD, Tuttle KD, Tyler KL Journal of NeuroVirology 2010 Aug 16 307-318
    • Fas-mediated apoptotic signaling in the mouse brain following reovirus infection
      Clarke P, Beckham JD, Leser JS, Hoyt CC, Tyler KL Journal of virology 2009 Jun 83 6161-6170
    • Reovirus activates transforming growth factor β and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection
      Beckham JD, Tuttle K, Tyler KL Journal of virology 2009 May 83 5035-5045
    • North American Encephalitic Arboviruses
      Davis LE, Beckham JD, Tyler KL Neurologic Clinics 2008 Aug 26 727-757
    • Management of acute shingles (herpes zoster)
      Tyler KL, Beckham JD Reviews in Neurological Diseases 2007 Sep 4 203-208
    • JAK-STAT signaling pathways are activated in the brain following reovirus infection
      Goody RJ, Beckham JD, Rubtsova K, Tyler KL Journal of NeuroVirology 2007 Jul 13 373-383
    • Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-jun N-terminal kinase
      Beckham JD, Goody RJ, Clarke P, Bonny C, Tyler KL Journal of virology 2007 Jul 81 6984-6992
    • Initial management of acute bacterial meningitis in adults: Summary of IDSA guidelines
      Beckham JD, Tyler KL Reviews in Neurological Diseases 2006 Mar 3 57-60
    • Multiple sclerosis treatment complications
      Beckham JD, Tyler KL Reviews in Neurological Diseases 2005 Jun 2 158-163
    • Respiratory viral infections in patients with chronic, obstructive pulmonary disease
      Beckham JD, Cadena A, Lin J, Piedra PA, Glezen WP, Greenberg SB, Atmar RL Journal of Infection 2005 May 50 322-330
Research
  • Virology and vaccine approaches associated with emerging RNA viruses
  • Unique immune responses in the brain that prevent infections but may also contribute to neurodegenerative diseases such as Parkinson’s disease

Clinical Focus

  • General Infectious Diseases
  • Neurological Infections
  • Human Immunodeficiency Virus

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Appointment New Patient Appointment or 214-645-2800