- American Academy of Pediatrics
- American Association of Immunologists
- Perinatal Research Society
- Society for Pediatric Research
- Southern Society for Pediatric Research
Julie Mirpuri-Hathiramani, M.D.
- Pediatrics - Neonatal-Perinatal
- Neonatal-Perinatal Medicine
Biography
Julie Mirpuri-Hathiramani, M.D., is an Associate Professor in the Department of Pediatrics at UT Southwestern Medical Center. She specializes in neonatal-perinatal medicine.
Dr. Mirpuri-Hathiramani earned her medical degree at the University of Hong Kong. She completed her residency in pediatrics at Atlantic Health’s Goryeb Children’s Hospital in Morristown, New Jersey, followed by a fellowship in neonatal-perinatal medicine at Grady Memorial Hospital in Atlanta.
Certified by the American Board of Pediatrics in pediatrics and neonatal-perinatal medicine, she joined the UT Southwestern faculty in 2010.
A physician-scientist, Dr. Mirpuri-Hathiramani’s research focuses on neonatal mucosal immunology, neonatal microbiome development, and necrotizing enterocolitis with a goal of developing novel therapies to improve the health of babies. She has delivered national and regional invited lectures and published numerous academic articles related to her areas of expertise.
She is a member of the American Academy of Pediatrics, the Southern Society for Pediatric Research, the American Association of Immunologists, the Society for Pediatric Research, and the Perinatal Research Society.
Personal Note
When she’s not at work, Dr. Mirpuri-Hathiramani enjoys reading, doing advocacy work, cooking, and watching all things “Star Wars.”
Education & Training
- Residency - Goryeb Children's Hospital - Atlantic Health (2004-2007), Pediatrics
- Internship - Hospital Authority of Hong Kong (2000-2001), Rotating
- Fellowship - Emory University School of Medicine/Grady Memorial Hospital (2007-2010), Neonatal-perinatal Medicine
- Medical School - Univeristy of Hong Kong (1995-2000)
Professional Associations & Affiliations
Honors & Awards
- First Place Basic Science Young Investigator Award: Mentor for fellow Tuan Tran, M.D. 2023, Southern Society for Pediatric Research
- Early Career Faculty Travel Grant 2019, American Association of Immunologists
- NIH Young Investigator Award 2018, Perinatal Research Society
- Dean’s LEAD Program Capstone Project Recognition Award 2016, UT Southwestern Office of Faculty Diversity & Development
- Travel Scholarship 2011, Federation of American Societies for Experimental Biology
- Basic Science Young Investigator Award 2010, Southern Society for Pediatric Research
- Fellow Basic Science Research Award 2010, Society for Pediatric Research
- Travel Award 2009, Southern Society for Pediatric Research
Books & Publications
-
Publications
-
Gut Microbiome Composition and Variance Are Modified by Degree of Growth Failure in Preterm Infants: A Prospective Study
Stumpf KA, Green M, Niu X, Lu D, Gan S, Zhan X, Maxey MN, Boren M, Nayak SP, Jaleel S, Brown LS, Foster JA, Mirpuri J Nutrients 2025 Dec 17 -
Maternal body mass index and necrotizing enterocolitis: A case-control study
Stumpf K, Sharma P, Brown LS, Brion LP, Mirpuri J PloS one 2024 Jan 19 -
Maternal high fat diet exposure modifies amniotic fluid metabolites and expands group 3 innate lymphoid cells dependent on the maternal microbiome and MyD88-signaling
Niu X, Lu D, Jaleel S, Palmer SN, Mahendroo M, Zhan X, Mirpuri J Frontiers in immunology 2024 15 -
Maternal Macro- and Micronutrient Intake During Pregnancy: Does It Affect Allergic Predisposition in Offspring?
Stumpf K, Mirpuri J Immunology and Allergy Clinics of North America 2023 Feb 43 27-42 -
Tachygastria in Preterm Infants: A Longitudinal Cohort Study
Ortigoza EB, Cagle J, Brown LS, Mansi S, Gosser SP, Montgomery AD, Foresman Z, Boren ML, Pettit PS, Thompson TD, Vasil DM, Chien JH, Neu J, Koh AY, Sanghavi R, Mirpuri J Journal of pediatric gastroenterology and nutrition 2022 Nov 75 564-571 -
Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet
Daniel S, Phillippi D, Schneider LJ, Nguyen KN, Mirpuri J, Lund AK Particle and Fibre Toxicology 2021 Dec 18 -
Maternal microbial factors that affect the fetus and subsequent offspring
Mirpuri J, Neu J Seminars in Perinatology 2021 Oct 45 -
Traffic generated emissions alter the lung microbiota by promoting the expansion of Proteobacteria in C57Bl/6 mice placed on a high-fat diet
Daniel S, Pusadkar V, McDonald J, Mirpuri J, Azad RK, Goven A, Lund AK Ecotoxicology and Environmental Safety 2021 Apr 213 -
Evidence for maternal diet-mediated effects on the offspring microbiome and immunity: implications for public health initiatives
Mirpuri J Pediatric Research 2021 Jan 89 301-306 -
Transient neonatal antibiotic exposure increases susceptibility to late-onset sepsis driven by microbiota-dependent suppression of type 3 innate lymphoid cells
Niu X, Daniel S, Kumar D, Ding EY, Savani RC, Koh AY, Mirpuri J Scientific reports 2020 Dec 10 -
Maternal high-fat diet results in microbiota-dependent expansion of ILC3s in mice offspring
Babu ST, Niu X, Raetz M, Savani RC, Hooper LV, Mirpuri J JCI Insight 2018 Oct 3 -
Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi
Song J, Wilhelm CL, Wangdi T, Maira-Litran T, Lee SJ, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Bäumler AJ, Pier GB, Galán JE, Yarovinsky F Cell 2016 Feb 164 827-828 -
The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia
Liao J, Kapadia VS, Brown LS, Cheong N, Longoria C, Mija D, Ramgopal M, Mirpuri J, McCurnin DC, Savani RC Nature communications 2015 Nov 6 -
Short-term outcomes for preterm infants with surgical necrotizing enterocolitis
Murthy K, Yanowitz TD, Digeronimo R, Dykes FD, Zaniletti I, Sharma J, Sullivan KM, Mirpuri J, Evans JR, Wadhawan R, Piazza A, Adams-Chapman I, Asselin JM, Short BL, Padula MA, Durand DJ, Pallotto EK, Reber KM Journal of Perinatology 2014 Oct 34 736-740 -
Proteobacteria-specific IgA regulates maturation of the intestinal microbiota
Mirpuri J, Raetz M, Sturge CR, Wilhelm CL, Benson A, Savani RC, Hooper LV, Yarovinsky F Gut Microbes 2013 Sep 5 28-39 -
TLR-independent neutrophil-derived IFN-γ is important for host resistance to intracellular pathogens
Sturge CR, Benson A, Raetz M, Wilhelm CL, Mirpuri J, Vitetta ES, Yarovinsky F Proceedings of the National Academy of Sciences of the United States of America 2013 Jun 110 10711-10716 -
Parasite-induced T H 1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells
Raetz M, Hwang SH, Wilhelm CL, Kirkland D, Benson A, Sturge CR, Mirpuri J, Vaishnava S, Hou B, Defranco AL, Gilpin CJ, Hooper LV, Yarovinsky F Nature immunology 2013 Feb 14 136-142 -
Lactobacillus rhamnosus (LGG) Regulates IL-10 Signaling in the Developing Murine Colon through Upregulation of the IL-10R2 Receptor Subunit
Mirpuri J, Sotnikov I, Myers L, Denning TL, Yarovinsky F, Parkos CA, Denning PW, Louis NA PloS one 2012 Dec 7 -
Prolonged persistent patent ductus arteriosus: Potential perdurable anomalies in premature infants
Saldeño YP, Favareto V, Mirpuri J Journal of Perinatology 2012 Dec 32 953-958 -
Therapeutic Helminth Infection of Macaques with Idiopathic Chronic Diarrhea Alters the Inflammatory Signature and Mucosal Microbiota of the Colon
Broadhurst MJ, Ardeshir A, Kanwar B, Mirpuri J, Gundra UM, Leung JM, Wiens KE, Vujkovic-Cvijin I, Kim CC, Yarovinsky F, Lerche NW, McCune JM, Loke P PLoS pathogens 2012 Nov 8 -
Trefoil factor 2 negatively regulates type 1 immunity against Toxoplasma gondii
McBerry C, Egan CE, Rani R, Yang Y, Wu D, Boespflug N, Boon L, Butcher B, Mirpuri J, Hogan SP, Denkers EY, Aliberti J, Herbert DR Journal of Immunology 2012 Sep 189 3078-3084 -
B Cell-Intrinsic MyD88 Signaling Prevents the Lethal Dissemination of Commensal Bacteria during Colonic Damage
Kirkland D, Benson A, Mirpuri J, Pifer R, Hou B, DeFranco AL, Yarovinsky F Immunity 2012 Feb 36 228-238 -
IL-6 signaling SOCS critical for IL-12 host response to Toxoplasma gondii
Mirpuri J, Yarovinsky F Future Microbiology 2012 Jan 7 13-16 -
Issues of prematurity and HIV infection
Mirpuri J, Jain L Clinics in Perinatology 2010 Dec 37 887-905 -
Commensal Escherichia coli reduces epithelial apoptosis through IFN-αA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine
Mirpuri J, Brazil JC, Berardinelli AJ, Nasr TR, Cooper K, Schnoor M, Lin PW, Parkos CA, Louis NA Journal of Immunology 2010 Jun 184 7186-7195
-
Gut Microbiome Composition and Variance Are Modified by Degree of Growth Failure in Preterm Infants: A Prospective Study
Research
- Neonatal mucosal immunology
- Neonatal microbiome
- Necrotizing enterocolitis
Clinical Focus
- Neonatal-Perinatal Medicine