- Residency - Goryeb Children's Hospital - Atlantic Health (2004-2007), Pediatrics
- Medical School - Univeristy of Hong Kong (1995-2000)
- Internship - Hospital Authority of Hong Kong (2000-2001), Rotating
- Fellowship - Emory University School of Medicine/Grady Memorial Hospital (2007-2010), Neonatal-perinatal Medicine
Julie Mirpuri-Hathiramani, M.D.
- Pediatrics - Neonatal-Perinatal
Education & Training
Professional Associations & Affiliations
- Medical Council of Hong Kong
- American Academy of Pediatrics (2004)
- Southern Society for Pediatric Research (2007)
- The American Association of Immunologists (2013)
Honors & Awards
- Travel Grant, Pediatric Academic Societies 2009
- Trainee Travel Award, Southern Society for Pediatric Research 2009
- SPR Fellow Basic Science Research Award 2010
- Basic Science Young Investigator Award, Southern Society for Pediatric Research 2010
- FASEB Travel Scholarship 2011
Books & Publications
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Publications
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The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia.
Liao J, Kapadia VS, Brown LS, Cheong N, Longoria C, Mija D, Ramgopal M, Mirpuri J, McCurnin DC, Savani RC Nature communications 2015 6 8977 -
Trefoil factor 2 negatively regulates type 1 immunity against Toxoplasma gondii.
McBerry C, Egan CE, Rani R, Yang Y, Wu D, Boespflug N, Boon L, Butcher B, Mirpuri J, Hogan SP, Denkers EY, Aliberti J, Herbert DR Journal of immunology (Baltimore, Md. : 1950) 2012 Sep 189 6 3078-84 -
Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi.
Song J, Wilhelm CL, Wangdi T, Maira-Litran T, Lee SJ, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Bäumler AJ, Pier GB, Galán JE, Yarovinsky F Cell 2016 Feb 164 5 827-8 -
TLR-independent neutrophil-derived IFN-? is important for host resistance to intracellular pathogens.
Sturge CR, Benson A, Raetz M, Wilhelm CL, Mirpuri J, Vitetta ES, Yarovinsky F Proceedings of the National Academy of Sciences of the United States of America 2013 Jun 110 26 10711-6 -
Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-?-dependent elimination of Paneth cells.
Raetz M, Hwang SH, Wilhelm CL, Kirkland D, Benson A, Sturge CR, Mirpuri J, Vaishnava S, Hou B, Defranco AL, Gilpin CJ, Hooper LV, Yarovinsky F Nature immunology 2013 Feb 14 2 136-42 -
B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage.
Kirkland D, Benson A, Mirpuri J, Pifer R, Hou B, DeFranco AL, Yarovinsky F Immunity 2012 Feb 36 2 228-38 -
Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine.
Mirpuri J, Brazil JC, Berardinelli AJ, Nasr TR, Cooper K, Schnoor M, Lin PW, Parkos CA, Louis NA Journal of immunology (Baltimore, Md. : 1950) 2010 Jun 184 12 7186-95 -
Issues of prematurity and HIV infection.
Mirpuri J, Jain L Clinics in perinatology 2010 Dec 37 4 887-905, xi -
Maternal high-fat diet results in microbiota-dependent expansion of ILC3s in mice offspring.
Babu ST, Niu X, Raetz M, Savani RC, Hooper LV, Mirpuri J JCI insight 2018 Oct 3 19 -
Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.
Broadhurst MJ, Ardeshir A, Kanwar B, Mirpuri J, Gundra UM, Leung JM, Wiens KE, Vujkovic-Cvijin I, Kim CC, Yarovinsky F, Lerche NW, McCune JM, Loke P PLoS pathogens 2012 8 11 e1003000 -
Proteobacteria-specific IgA regulates maturation of the intestinal microbiota.
Mirpuri J, Raetz M, Sturge CR, Wilhelm CL, Benson A, Savani RC, Hooper LV, Yarovinsky F Gut microbes 2013 Sep 5 1 -
Lactobacillus rhamnosus (LGG) regulates IL-10 signaling in the developing murine colon through upregulation of the IL-10R2 receptor subunit.
Mirpuri J, Sotnikov I, Myers L, Denning TL, Yarovinsky F, Parkos CA, Denning PW, Louis NA PloS one 2012 7 12 e51955 -
IL-6 signaling SOCS critical for IL-12 host response to Toxoplasma gondii.
Mirpuri J, Yarovinsky F Future microbiology 2012 Jan 7 1 13-6
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The NLRP3 inflammasome is critically involved in the development of bronchopulmonary dysplasia.
Research
- Probiotics/Commensal organisms and their effects on immune mediators in the developing gut