- Residency - Govt. Stanley Medical College Hospital (1993-1995), Internal Medicine & Pediatrics
- Medical School - Stanley Medical College and Hospital (1988-1994)
- Residency - The Royal Bolton Hospital (1996-2003), Pediatrics
- Residency - Driscoll Children's Hospital - GME (2003-2005), Pediatrics
- Fellowship - UT Southwestern/Children's Medical Center (2005-2008), Pediatric Nephrology
- Fellowship - UT Southwestern Medical Center (2008-2009), Nephrology
Jyothsna Gattineni, M.D.
Chief, Division of Pediatric Nephrology
- Pediatrics - Nephrology
- Chronic Kidney Disease
- Cardiorenal syndromes
Jyothsna Gattineni, M.D., is an Associate Professor in the Department of Pediatrics at UT Southwestern Medical Center. She specializes in kidney disease, especially disorders of phosphate regulation, nephrolithiasis, hemolytic uremic syndrome, dialysis modalities, mineral and bone disorders in chronic kidney disease, and cardiorenal syndromes.
Dr. Gattineni earned her medical degree at Stanley Medical College and Hospital in Chennai, India. She also received postdoctoral training at Booth Hall Children’s Hospital, Royal Manchester Children’s Hospital, and Royal Bolton Hospital in the United Kingdom and earned a Membership of the Royal Colleges of Physicians (MRCP) from the Royal College of Physicians of Edinburgh. She completed a residency in pediatrics at Driscoll Children’s Hospital at Texas A&M University and gained advanced training through a fellowship in pediatric nephrology at UT Southwestern.
Certified by the American Board of Pediatrics in general pediatrics and pediatric nephrology, she joined the UT Southwestern faculty in 2009.
Among her other roles at UTSW, Dr. Gattineni serves as Chief of the Division of Pediatric Nephrology and Medical Director of Dialysis for the Department of Pediatrics.
She is also a physician-scientist, and her laboratory’s research focuses on identifying the role of fibroblast growth factor 23 (FGF23) in cardiovascular disease, both with and without kidney disease. She has delivered scores of presentations, contributed to five books, and published numerous academic articles related to her areas of expertise.
Dr. Gattineni is on the editorial board for Pediatric Nephrology and the American Academy of Pediatrics’s Prep Pediatric Nephrology. She is a member of the American Society of Nephrology, the International Society of Nephrology, the American Society of Pediatric Nephrology, the International Pediatric Nephrology Association, the American Academy of Pediatrics, and the Society for Pediatric Research.
In 2020, she received UT Southwestern’s Best Pediatric Faculty Teaching Award.
- American Academy of Pediatrics
- American Society of Nephrology
- American Society of Pediatric Nephrology
- International Pediatric Nephrology Association
- International Society of Nephrology
- Society for Pediatric Research
- DFW Child Mom-Approved Pediatric Specialist 2021
- Best Doctors 2017-2021, D Magazine
- Best Pediatric Faculty Teaching Award 2020, UT Southwestern
- Top 5 Capstone Projects 2019, UT Southwestern’s Leadership Emerging in Academic Departments Program
Postnatal Renal Development. in Alpern RJ, Caplan MJ, Moe OW, eds. Seldin and Giebisch's The Kidney: Physiology and Pathophysiology. 5th ed.
Baum M, Gattineni J, Satlin LM. (2013), Elsevier; 911-932.
Regulation of Hormone-Sensitive Renal Phosphate Transport in Litwack G, ed. Hormones and Transport Systems: Vitamins and Hormones. Vol 98.
Gattineni J, Friedman PA. (2015), Elsevier; 249-306.
Inherited Disorders of Calcium, Phosphate and Magnesium in Nephrology and Fluid /Electrolytes Physiology: Neonatology Questions and Controversies
Gattineni J, Wolf MT (2018)
Assessing Kidney Function in Pediatric Nephrology, 8th Edition
Filler G, Ferris M, Gattineni J (2020), In submission
Kidney Stone in the Non-Ambulatory Child in Diagnosis and Management of Pediatric Nephrolithiasis
Passoni, N, Gattineni, J and Baker, L (2020), In writing
- Postnatal Renal Development. in Alpern RJ, Caplan MJ, Moe OW, eds. Seldin and Giebisch's The Kidney: Physiology and Pathophysiology. 5th ed.
Genetic disorders of phosphate regulation.
Gattineni J, Baum M Pediatric nephrology (Berlin, Germany) 2012 Sep 27 9 1477-87
Effect of metabolic acidosis on neonatal proximal tubule acidification.
Twombley K, Gattineni J, Bobulescu IA, Dwarakanath V, Baum M American journal of physiology. Regulatory, integrative and comparative physiology 2010 Nov 299 5 R1360-8
Cytoplasmic RNA quality control failure engages mTORC1-mediated autoinflammatory disease.
Yang K, Han J, Asada M, Gill JG, Park JY, Sathe MN, Gattineni J, Wright T, Wysocki CA, de la Morena MT, Garza LA, Yan N, The Journal of clinical investigation 2022 Jan 132 2
Phenotypic Severity Scoring System and Categorization for Prune Belly Syndrome: Application to a Pilot Cohort of 50 Living Patients.
Wong DG, Arevalo MK, Passoni NM, Iqbal NS, Jascur T, Kern AJ, Sanchez EJ, Satyanarayan A, Gattineni J, Baker LA BJU international 2018 Aug
Effect of sex on glomerular filtration rate in programmed rats by prenatal dexamethasone.
Jain J, Legan SK, Alhamoud I, Gattineni J, Baum M, Physiological reports 2019 Jul 7 12 e14154
Donation after cardiac death kidneys are suitable for pediatric recipients.
MacConmara M, El Mokdad A, Gattineni J, Hwang CS, Pediatric transplantation 2019 Jul e13540
Utilizing increased risk for disease transmission (IRD) kidneys for pediatric renal transplant recipients.
Hwang CS, Gattineni J, MacConmara M, Pediatric nephrology (Berlin, Germany) 2019 Jun
Regulation of Renal Phosphate Transport by FGF23 is Mediated by FGFR1 and FGFR4.
Gattineni J, Alphonse P, Zhang Q, Mathews N, Bates CM, Baum M American journal of physiology. Renal physiology 2013 Nov
Effect of Postnatal Maternal Protein Intake on Prenatal Programming of Hypertension.
Siddique K, Guzman GL, Gattineni J, Baum M Reproductive sciences (Thousand Oaks, Calif.) 2014 Apr
Regulation of hormone-sensitive renal phosphate transport.
Gattineni J, Friedman PA Vitamins and hormones 2015 98 249-306
Sex differences in prenatal programming of hypertension by dexamethasone.
Alhamoud I, Legan SK, Gattineni J, Baum M, Experimental biology and medicine (Maywood, N.J.) 2021 Apr 15353702211003294
Clinicopathological features of C3 glomerulopathy in children: a single-center experience.
Drake KA, Ellington N, Gattineni J, Torrealba JR, Hendricks AR, Pediatric nephrology (Berlin, Germany) 2019 Oct
Proliferative Glomerulonephritis with Monoclonal Immunoglobulin G Lambda Deposits: Report of the First Pediatric Case.
Torrealba J, Gattineni J, Hendricks AR Case reports in nephrology and dialysis 2018 Jan-Apr 8 1 70-75
Proximal tubule Na+/H+ exchanger activity in adult NHE8-/-, NHE3-/-, and NHE3-/-/NHE8-/- mice.
Baum M, Twombley K, Gattineni J, Joseph C, Wang L, Zhang Q, Dwarakanath V, Moe OW American journal of physiology. Renal physiology 2012 Dec 303 11 F1495-502
Transient enalapril attenuates the reduction in glomerular filtration rate in prenatally programmed rats.
Mansuri A, Elmaghrabi A, Alhamoud I, Legan SK, Gattineni J, Baum M Physiological reports 2017 Apr 5 8
Familial hyperkalemic hypertension: hyperkalemia not hypertension defines dominant KLHL3 disease and may permit earlier recognition and tailored therapy.
Sambharia M, Gattineni J, Noureddine L, Mansilla MA, Thomas CP, Journal of nephrology 2022 Jan
Accidental and iatrogenic causes of acute kidney injury.
Twombley K, Baum M, Gattineni J Current opinion in pediatrics 2011 Apr 23 2 208-14
Prenatal programming of rat thick ascending limb chloride transport by low-protein diet and dexamethasone.
Dagan A, Habib S, Gattineni J, Dwarakanath V, Baum M American journal of physiology. Regulatory, integrative and comparative physiology 2009 Jul 297 1 R93-9
Pediatric nephrology: highlights for the general practitioner.
Seikaly M, Habib S, Barakat AJ, Gattineni J, Quigley R, Desi D International journal of pediatrics 2012 2012 270725
Prenatal programming of rat proximal tubule Na+/H+ exchanger by dexamethasone.
Dagan A, Gattineni J, Cook V, Baum M American journal of physiology. Regulatory, integrative and comparative physiology 2007 Mar 292 3 R1230-5
Effect of renal denervation on urine angiotensinogen excretion in prenatally programmed rats.
Mansuri A, Legan SK, Jain J, Alhamoud I, Gattineni J, Baum M Physiological reports 2017 Nov 5 20
FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.
Gattineni J, Bates C, Twombley K, Dwarakanath V, Robinson ML, Goetz R, Mohammadi M, Baum M American journal of physiology. Renal physiology 2009 Aug 297 2 F282-91
Effect of prenatal dexamethasone on postnatal serum and urinary angiotensin II levels.
Dagan A, Gattineni J, Habib S, Baum M American journal of hypertension 2010 Apr 23 4 420-4
Evidence that prenatal programming of hypertension by dietary protein deprivation is mediated by fetal glucocorticoid exposure.
Habib S, Gattineni J, Twombley K, Baum M American journal of hypertension 2011 Jan 24 1 96-101
Nucleotide Sequence of the Na+/H+ Exchanger-8 (NHE8) in Patients with Congenital Sodium Diarrhea.
Baum M, Martin MG, Booth IW, Holmberg C, Twombley K, Zhang Q, Gattineni J, Moe O Journal of pediatric gastroenterology and nutrition 2011 Jun
Regulation of Serum 1,25(OH)2Vitamin D3 levels by Fibroblast Growth Factor 23 is Mediated by FGF Receptors 3 and 4.
Gattineni J, Twombley K, Goetz R, Mohammadi M, Baum M American journal of physiology. Renal physiology 2011 May F371-7
Acid increases NHE8 surface expression and activity in NRK cells.
Joseph C, Twombley K, Gattineni J, Zhang Q, Dwarakanath V, Baum M American journal of physiology. Renal physiology 2012 Feb 302 4 F495-503
Effect of Prenatal Programming and Postnatal Rearing on Glomerular Filtration Rate in Adult Rats.
Lozano G, Elmaghrabi A, Salley J, Siddique K, Gattineni J, Baum M American journal of physiology. Renal physiology 2014 Dec ajprenal.00593.2014
Transient Exposure of Enalapril Normalizes Prenatal Programming of Hypertension and Urinary Angiotensinogen Excretion.
Mansuri A, Elmaghrabi A, Legan SK, Gattineni J, Baum M PloS one 2015 10 12 e0146183
Mercury intoxication: lack of correlation between symptoms and levels.
Gattineni J, Weiser S, Becker AM, Baum M Clinical pediatrics 2007 Nov 46 9 844-6
Effect of thyroid hormone on the postnatal renal expression of NHE8.
Gattineni J, Sas D, Dagan A, Dwarakanath V, Baum M American journal of physiology. Renal physiology 2008 Jan 294 1 F198-204
Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): implications for disorders of phosphate metabolism.
Gattineni J, Baum M Pediatric nephrology (Berlin, Germany) 2010 Apr 25 4 591-601
Glucocorticoids Reduce Renal NHE8 Expression.
Joseph C, Gattineni J, Dwarakanath V, Baum M Physiological reports 2013 Aug 1 2
Complement disorders and hemolytic uremic syndrome.
Joseph C, Gattineni J Current opinion in pediatrics 2013 Feb
Renal NHE Expression and Activity in Neonatal NHE3 and NHE8 Null Mice.
Pirojsakul K, Gattineni J, Dwarakanath V, Baum M American journal of physiology. Renal physiology 2014 Nov ajprenal.00492.2014
Proteinuria and hematuria in the neonate.
Joseph C, Gattineni J Current opinion in pediatrics 2016 Feb
Developmental changes in renal tubular transport-an overview.
Gattineni J, Baum M Pediatric nephrology (Berlin, Germany) 2013 Nov
Highlights for the management of a child with proteinuria and hematuria.
Gattineni J International journal of pediatrics 2012 2012 768142
Inherited disorders of calcium and phosphate metabolism.
Gattineni J Current opinion in pediatrics 2014 Feb
- Genetic disorders of phosphate regulation.
- Fibroblast Growth Factor 23 and its receptors
- Fibroblast Growth Factor 23 and cardiovascular disease
- Tubular Transport
- Chronic Kidney Disease
- Cardiorenal syndromes
- Mineral and bone disorders
- Dialysis modalities
- Disorders of phosphate regulation
- Hemolytic uremic syndrome