- American Academy of Pediatrics
- American Society of Nephrology
- American Society of Pediatric Nephrology
- International Pediatric Nephrology Association
- International Society of Nephrology
- Society for Pediatric Research
Jyothsna Gattineni, M.D.
Chief, Division of Pediatric Nephrology
- Pediatrics - Nephrology
- Chronic Kidney Disease
- Cardiorenal syndromes
Biography
Jyothsna Gattineni, M.D., is an Associate Professor in the Department of Pediatrics at UT Southwestern Medical Center. She specializes in kidney disease, especially disorders of phosphate regulation, nephrolithiasis, hemolytic uremic syndrome, dialysis modalities, mineral and bone disorders in chronic kidney disease, and cardiorenal syndromes.
Dr. Gattineni earned her medical degree at Stanley Medical College and Hospital in Chennai, India. She also received postdoctoral training at Booth Hall Children’s Hospital, Royal Manchester Children’s Hospital, and Royal Bolton Hospital in the United Kingdom and earned a Membership of the Royal Colleges of Physicians (MRCP) from the Royal College of Physicians of Edinburgh. She completed a residency in pediatrics at Driscoll Children’s Hospital at Texas A&M University and gained advanced training through a fellowship in pediatric nephrology at UT Southwestern.
Certified by the American Board of Pediatrics in general pediatrics and pediatric nephrology, she joined the UT Southwestern faculty in 2009.
Among her other roles at UTSW, Dr. Gattineni serves as Chief of the Division of Pediatric Nephrology and Medical Director of Dialysis for the Department of Pediatrics.
She is also a physician-scientist, and her laboratory’s research focuses on identifying the role of fibroblast growth factor 23 (FGF23) in cardiovascular disease, both with and without kidney disease. She has delivered scores of presentations, contributed to five books, and published numerous academic articles related to her areas of expertise.
Dr. Gattineni is on the editorial board for Pediatric Nephrology and the American Academy of Pediatrics’s Prep Pediatric Nephrology. She is a member of the American Society of Nephrology, the International Society of Nephrology, the American Society of Pediatric Nephrology, the International Pediatric Nephrology Association, the American Academy of Pediatrics, and the Society for Pediatric Research.
In 2020, she received UT Southwestern’s Best Pediatric Faculty Teaching Award.
Education & Training
- Residency - Govt. Stanley Medical College Hospital (1993-1995), Internal Medicine & Pediatrics
- Medical School - Stanley Medical College and Hospital (1988-1994)
- Residency - The Royal Bolton Hospital (1996-2003), Pediatrics
- Residency - Driscoll Children's Hospital - GME (2003-2005), Pediatrics
- Fellowship - UT Southwestern/Children's Medical Center (2005-2008), Pediatric Nephrology
- Fellowship - UT Southwestern Medical Center (2008-2009), Nephrology
Professional Associations & Affiliations
Honors & Awards
- DFW Child Mom-Approved Pediatric Specialist 2021
- D Magazine Best Doctor 2017-2025
- Best Pediatric Faculty Teaching Award 2020, UT Southwestern
- Top 5 Capstone Projects 2019, UT Southwestern’s Leadership Emerging in Academic Departments Program
Books & Publications
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Books
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Postnatal Renal Development. in Alpern RJ, Caplan MJ, Moe OW, eds. Seldin and Giebisch's The Kidney: Physiology and Pathophysiology. 5th ed.
Baum M, Gattineni J, Satlin LM. (2013), Elsevier; 911-932. -
Regulation of Hormone-Sensitive Renal Phosphate Transport in Litwack G, ed. Hormones and Transport Systems: Vitamins and Hormones. Vol 98.
Gattineni J, Friedman PA. (2015), Elsevier; 249-306. -
Inherited Disorders of Calcium, Phosphate and Magnesium in Nephrology and Fluid /Electrolytes Physiology: Neonatology Questions and Controversies
Gattineni J, Wolf MT (2018) -
Assessing Kidney Function in Pediatric Nephrology, 8th Edition
Filler G, Ferris M, Gattineni J (2020), In submission -
Kidney Stone in the Non-Ambulatory Child in Diagnosis and Management of Pediatric Nephrolithiasis
Passoni, N, Gattineni, J and Baker, L (2020), In writing
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Postnatal Renal Development. in Alpern RJ, Caplan MJ, Moe OW, eds. Seldin and Giebisch's The Kidney: Physiology and Pathophysiology. 5th ed.
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Publications
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Updates in atypical hemolytic syndrome
Drake K, Gattineni J Current opinion in pediatrics 2026 Apr 38 219-225 -
Pediatric Nephrology Practice in the United States: Survey of Pediatric Nephrology Division Directors
Author Collaboration AD, Verghese PS, Bobrowski A, Carter C, Dharnidharka VR, Gattineni J, Goodwin JE, Kershaw DB, Mauch TJ, Nelson R, Subtirelu M, Flynn J, Feig D American Journal of Kidney Diseases 2025 Jul 86 74-83 -
Acetaminophen induced high anion gap metabolic acidosis: a potentially under-recognized consequence from a common medication
Gaur D, Michalopulos MG, Drake KA, Gattineni J Pediatric Nephrology 2025 Jan 40 99-101 -
The role of fibroblast growth factor 23 in regulation of phosphate balance
Wilson R, Mukherjee-Roy N, Gattineni J Pediatric Nephrology 2024 Dec 39 3439-3451 -
Correction: Use of ClearGuard HD caps in pediatric hemodialysis patients (Pediatric Nephrology, (2024), 39, 7, (2171-2175), 10.1007/s00467-023-06273-6)
Nau A, Richardson T, Cardwell D, Ehrlich J, Gattineni J, Hanna M, Keswani M, Neibauer E, Nitz K, Quigley R, Rheault M, Sims R, Woo M, Warady BA Pediatric Nephrology 2024 Aug 39 2541 -
Use of ClearGuard HD caps in pediatric hemodialysis patients
Nau A, Richardson T, Cardwell D, Ehrlich J, Gattineni J, Hanna M, Keswani M, Neibauer E, Nitz K, Quigley R, Rheault M, Sims R, Woo M, Warady BA Pediatric Nephrology 2024 Jul 39 2171-2175 -
C3 glomerulopathy in a patient with a history of post-infectious glomerulonephritis
Nnadi N, Hendricks AR, Torrealba JR, Drake KA, Gattineni J Pediatric Nephrology 2024 Mar 39 745-748 -
Familial hyperkalemic hypertension: hyperkalemia not hypertension defines dominant KLHL3 disease and may permit earlier recognition and tailored therapy
Sambharia M, Gattineni J, Noureddine L, Mansilla MA, Thomas CP Journal of Nephrology 2022 Jul 35 1737-1742 -
The mammalian SKIV2L RNA exosome is essential for early B cell development
Yang K, Han J, Gill JG, Park JY, Sathe MN, Gattineni J, Wright T, Wysocki C, de la Morena MT, Yan N Science Immunology 2022 May 7 -
Assessment of Kidney Function in Children, Adolescents, and Young Adults
Filler G, Ferris M, Gattineni J 2022 Jan 145-171 -
Cytoplasmic RNA quality control failure engages mTORC1-mediated autoinflammatory disease
Yang K, Han J, Asada M, Gill JG, Park JY, Sathe MN, Gattineni J, Wright T, Wysocki CA, Teresa de la Morena M, Garza LA, Yan N Journal of Clinical Investigation 2022 Jan 132 -
Papers presented at the fall 2020 Pediatric Urologic Oncology Work Group of the Societies of Pediatric Urology meetingNeonatal Serum Electrolyte and Proteinuria Screening on 46,XY Ambiguous Genitalia Patients May Allow Early Diagnosis of Denys-Drash Syndrome: A Case Report
Edwards A, Passoni NM, Collins R, Vidi S, Gattineni J, Baker LA Urology 2021 Jul 153 312-316 -
Sex differences in prenatal programming of hypertension by dexamethasone
Alhamoud I, Legan SK, Gattineni J, Baum M Experimental Biology and Medicine 2021 Jul 246 1554-1562 -
Clinicopathological features of C3 glomerulopathy in children: a single-center experience
Drake KA, Ellington N, Gattineni J, Torrealba JR, Hendricks AR Pediatric Nephrology 2020 Jan 35 153-162 -
Donation after cardiac death kidneys are suitable for pediatric recipients
MacConmara M, El Mokdad A, Gattineni J, Hwang CS Pediatric Transplantation 2019 Nov 23 -
Utilizing increased risk for disease transmission (IRD) kidneys for pediatric renal transplant recipients
Hwang CS, Gattineni J, MacConmara M Pediatric Nephrology 2019 Oct 34 1743-1751 -
Effect of sex on glomerular filtration rate in programmed rats by prenatal dexamethasone
Jain J, Legan SK, Alhamoud I, Gattineni J, Baum M Physiological Reports 2019 Jul 7 -
Phenotypic severity scoring system and categorisation for prune belly syndrome: application to a pilot cohort of 50 living patients
Wong DG, Arevalo MK, Passoni NM, Iqbal NS, Jascur T, Kern AJ, Sanchez EJ, Satyanarayan A, Gattineni J, Baker LA BJU International 2019 Jan 123 130-139 -
Inherited Disorders of Calcium, Phosphate, and Magnesium
Gattineni J, Wolf MT 2018 Jan 345-389 -
Proliferative Glomerulonephritis with Monoclonal Immunoglobulin G Lambda Deposits: Report of the First Pediatric Case
Torrealba J, Gattineni J, Hendricks AR Case Reports in Nephrology and Dialysis 2018 Jan 8 70-75 -
Effect of renal denervation on urine angiotensinogen excretion in prenatally programmed rats
Mansuri A, Legan SK, Jain J, Alhamoud I, Gattineni J, Baum M Physiological Reports 2017 Nov 5 -
Transient enalapril attenuates the reduction in glomerular filtration rate in prenatally programmed rats
Mansuri A, Elmaghrabi A, Alhamoud I, Legan SK, Gattineni J, Baum M Physiological Reports 2017 Apr 5 -
Proteinuria and hematuria in the neonate
Joseph C, Gattineni J Current opinion in pediatrics 2016 Apr 28 202-208 -
Transient exposure of enalapril normalizes prenatal programming of hypertension and urinary angiotensinogen excretion
Mansuri A, Elmaghrabi A, Legan SK, Gattineni J, Baum M PloS one 2015 Dec 10 -
Developmental changes in renal tubular transport—an overview
Gattineni J, Baum M Pediatric Nephrology 2015 Dec 30 2085-2098 -
Effect of prenatal programming and postnatal rearing on glomerular filtration rate in adult rats
Lozano G, Elmaghrabi A, Salley J, Siddique K, Gattineni J, Baum M American Journal of Physiology - Renal Physiology 2015 308 F411-F419 -
Regulation of hormone-sensitive renal phosphate transport
Gattineni J, Friedman PA Vitamins and Hormones 2015 98 249-306 -
Renal NHE expression and activity in neonatal NHE3- and NHE8-null mice
Pirojsakul K, Gattineni J, Dwarakanath V, Baum M, Baum M American Journal of Physiology - Renal Physiology 2015 Jan 308 F31-F38 -
Effect of postnatal maternal protein intake on prenatal programming of hypertension
Siddique K, Guzman GL, Gattineni J, Baum M Reproductive Sciences 2014 Dec 21 1499-1507 -
Inherited disorders of calcium and phosphate metabolism
Gattineni J Current opinion in pediatrics 2014 Apr 26 215-222 -
Regulation of renal phosphate transport by FGF23 is mediated by FGFR1 and FGFR4
Gattineni J, Alphonse P, Zhang Q, Mathews N, Bates CM, Baum M American Journal of Physiology - Renal Physiology 2014 Feb 306 F351-F358 -
Glucocorticoids reduce renal NHE8 expression
Joseph C, Gattineni J, Dwarakanath V, Baum M Physiological Reports 2013 Jul 1 -
Complement disorders and hemolytic uremic syndrome
Joseph C, Gattineni J Current opinion in pediatrics 2013 Apr 25 209-215 -
Postnatal Renal Development
Baum M, Gattineni J, Satlin LM 2013 1 911-931 -
Proximal tubule Na+/H+ exchanger activity in adult NHE8-/-, NHE3-/-, and NHE3-/-/NHE8-/- mice
Baum M, Twombley K, Gattineni J, Joseph C, Wang L, Zhang Q, Dwarakanath V, Moe OW American Journal of Physiology - Renal Physiology 2012 Dec 303 F1495-F1502 -
Postnatal Renal Development
Baum M, Gattineni J, Satlin LM 2012 Dec 911-931 -
Genetic disorders of phosphate regulation
Gattineni J, Baum M Pediatric Nephrology 2012 Sep 27 1477-1487 -
Acid increases NHE8 surface expression and activity in NRK cells
Joseph C, Twombley K, Gattineni J, Zhang Q, Dwarakanath V, Baum M American Journal of Physiology - Renal Physiology 2012 Feb 302 F495-F503 -
Nucleotide sequence of the Na +/H + exchanger-8 in patients with congenital sodium diarrhea
Baum M, Martin MG, Booth IW, Holmberg C, Twombley K, Zhang Q, Gattineni J, Moe O Journal of pediatric gastroenterology and nutrition 2011 Nov 53 474-477 -
Regulation of serum 1,25(OH)2vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4
Gattineni J, Twombley K, Goetz R, Mohammadi M, Baum M American Journal of Physiology - Renal Physiology 2011 Aug 301 F371-F377 -
Accidental and iatrogenic causes of acute kidney injury
Twombley K, Baum M, Gattineni J Current opinion in pediatrics 2011 Apr 23 208-214 -
Evidence that prenatal programming of hypertension by dietary protein deprivation is mediated by fetal glucocorticoid exposure
Habib S, Gattineni J, Twombley K, Baum M American Journal of Hypertension 2011 Jan 24 96-101 -
Effect of metabolic acidosis on neonatal proximal tubule acidification
Twombley K, Gattineni J, Bobulescu IA, Dwarakanath V, Baum M American Journal of Physiology - Regulatory Integrative and Comparative Physiology 2010 Nov 299 R1360-R1368 -
Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): Implications for disorders of phosphate metabolism
Gattineni J, Baum M Pediatric Nephrology 2010 Apr 25 591-601 -
Effect of prenatal dexamethasone on postnatal serum and urinary angiotensin II levels
Dagan A, Gattineni J, Habib S, Baum M American Journal of Hypertension 2010 Apr 23 420-424 -
FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1
Gattineni J, Bates C, Twombley K, Dwarakanath V, Robinson ML, Goetz R, Mohammadi M, Baum M American Journal of Physiology - Renal Physiology 2009 Aug 297 F282-F291 -
Prenatal programming of rat thick ascending limb chloride transport by low-protein diet and dexamethasone
Dagan A, Habib S, Gattineni J, Dwarakanath V, Baum M American Journal of Physiology - Regulatory Integrative and Comparative Physiology 2009 Jul 297 R93-R99 -
Effect of thyroid hormone on the postnatal renal expression of NHE8
Gattineni J, Sas D, Dagan A, Dwarakanath V, Baum M American Journal of Physiology - Renal Fluid and Electrolyte Physiology 2008 Jan 294 F198-F204 -
Mercury intoxication: Lack of correlation between symptoms and levels
Gattineni J, Weiser S, Becker AM, Baum M Clinical Pediatrics 2007 Nov 46 844-846 -
Prenatal programming of rat proximal tubule Na+/H+ exchanger by dexamethasone
Dagan A, Gattineni J, Cook V, Baum M American Journal of Physiology - Regulatory Integrative and Comparative Physiology 2007 Mar 292 R1230-R1235
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Updates in atypical hemolytic syndrome
Research
- Fibroblast Growth Factor 23 and its receptors
- Fibroblast Growth Factor 23 and cardiovascular disease
- Tubular Transport
Clinical Focus
- Chronic Kidney Disease
- Cardiorenal syndromes
- Mineral and bone disorders
- Dialysis modalities
- Disorders of phosphate regulation
- Hemolytic uremic syndrome
- Nephrolithiasis
Children's Medical Center of Dallas
1935 Medical District DriveDallas, Texas 75235 214-730-5437 Directions to Children's Medical Center of Dallas at Children's Medical Center of Dallas, Dallas