Kartik Rajagopalan, M.D., Ph.D.

Internal Medicine - Pulmonary and Critical Care Medicine
Medical Critical Care

Biography

Kartik Rajagopalan, M.D., Ph.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He specializes in medical critical care.

Dr. Rajagopalan earned his doctoral degree in cancer biology and his medical degree at UT Southwestern through the Medical Scientist Training Program. He completed a residency in internal medicine and a fellowship in pulmonary and critical care at NewYork-Presbyterian Columbia University Medical Center.

He joined the UT Southwestern faculty in 2023.

Dr. Rajagopalan directs a research lab studying energy regulation during infection.

Personal Note

When he’s not at work, Dr. Rajagopalan enjoys reading, doing Brazilian jiu-jitsu, and hanging out with his wife and two daughters.

Education & Training

Medical School - UT Southwestern Medical School (2007-2016)
Residency - New York Presbyterian Hospital (Columbia Campus)) (2016-2018), Internal Medicine
Fellowship - New York - Presbyterian Hospital - Columbia Campus (2018-2021), Pulmonary & Critical Care Medicine

Honors & Awards

Stony Wold-Herbert Fellowship Grant Recipient 2021-2022
Rockefeller Clinical Scholars Program (KL2 grant) 2021-2023
T32 Training Grant 2020-2021, National Heart, Lung, and Blood Institute

Books & Publications

Books
- Sleep apnea in Netter’s Integrated Review of Medicine
  Rajagopalan KN, Augelli DM (2020), Philadelphia, PA, Elsevier
Publications
- Leptin signaling maintains autonomic stability during severe influenza infection in mice
  Muñoz-Rojas AR, Wang AC, Pomeranz LE, Reizis EL, Stout-Delgado HW, Miranda IC, Rajagopalan K, Gwatiringa T, Fan RR, Huda AA, Maskey N, Olumuyide RP, Patel AS, Friedman JM, Mathis D, Rajagopalan KN Journal of Clinical Investigation 2025 Jan 135
- Leptin signaling maintains autonomic stability during severe influenza infection in mice
  Munoz-Rojas AR, Wang AC, Pomeranz LE, Reizis EL, Stout-Delgado HW, Miranda I, Rajagopalan K, Gwatiringa T, Fan RR, Huda AA, Maskey N, Olumuyide RP, Patel AS, Friedman J, Mathis D, Rajagopalan KN Journal of Clinical Investigation 2024 Oct
- Cryptococcus neoformans Infective Endocarditis After Lung Transplantation: A Case Report and Review of the Literature
  Fountain JH, Rajagopalan KN, Carroll M, Robbins H, Benvenuto LJ, Shimbo D, Marboe CC, Arcasoy SM, Pereira MR Infectious Diseases in Clinical Practice 2021 Nov 29 E457-E461
- A randomized double-blind controlled trial of convalescent plasma in adults with severe COVID-19
  O'Donnell MR, Grinsztejn B, Cummings MJ, Justman JE, Lamb MR, Eckhardt CM, Philip NM, Cheung YK, Gupta V, João E, Pilotto JH, Diniz MP, Cardoso SW, Abrams D, Rajagopalan KN, Borden SE, Wolf A, Sidi LC, Vizzoni A, Veloso VG, Bitan ZC, Scotto DE, Meyer BJ, Jacobson SD, Kantor A, Mishra N, Chauhan LV, Stone EF, Zotti FD, La Carpia F, Hudson KE, Ferrara SA, Schwartz J, Stotler BA, Lin WH, Wontakal SN, Shaz B, Briese T, Hod EA, Spitalnik SL, Eisenberger A, Lipkin WI Journal of Clinical Investigation 2021 Jul 131
- Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation
  Rajagopalan KN, Chen X, Weinberg DN, Chen H, Majewski J, Allis CD, Lu C Proceedings of the National Academy of Sciences of the United States of America 2021 Mar 118
- Correction to: Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: A structured summary of a study protocol for a randomized controlled trial (Trials, (2020), 21, 1, (499), 10.1186/s13063-020-04422-y)
  Eckhardt CM, Cummings MJ, Rajagopalan KN, Borden S, Bitan ZC, Wolf A, Kantor A, Briese T, Meyer BJ, Jacobson SD, Scotto D, Mishra N, Philip NM, Stotler BA, Schwartz J, Shaz B, Spitalnik SL, Eisenberger A, Hod Jessica Justman EA, Cheung K, Lipkin WI, O’Donnell MR Trials 2020 Dec 21
- Body mass index and risk for intubation or death in SARS-CoV-2 infection: A retrospective cohort study
  Anderson MR, Geleris J, Anderson DR, Zucker J, Nobel YR, Freedberg D, Small-Saunders J, Rajagopalan KN, Greendyk R, Chae SR, Natarajan K, Roh D, Edwin E, Gallagher D, Podolanczuk A, Barr RG, Ferrante AW, Baldwin MR Annals of internal medicine 2020 Nov 173 782-790
- Erratum: Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: A structured summary of a study protocol for a randomized controlled trial (Trials (2020) 21 (499) DOI: 10.1186/s13063-020-04422-y)
  Eckhardt CM, Cummings MJ, Rajagopalan KN, Borden S, Bitan ZC, Wolf A, Kantor A, Briese T, Meyer BJ, Jacobson SD, Scotto D, Mishra N, Philip NM, Stotler BA, Schwartz J, Shaz B, Spitalnik SL, Eisenberger A, Hod EA, Justman J, Cheung K, Lipkin WI, O'Donnell MR Trials 2020 Jun 21
- Evalua ting the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: A structured summary of a study protocol for a randomized controlled trial
  Eckhardt CM, Cummings MJ, Rajagopalan KN, Borden S, Bitan ZC, Wolf A, Kantor A, Briese T, Meyer BJ, Jacobson SD, Scotto D, Mishra N, Philip NM, Stotler BA, Schwartz J, Shaz B, Spitalnik SL, Eisenberg A, Hod EA, Justman J, Cheung K, Lipkin WI, O'donnell MR Trials 2020 Jun 21
- The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape
  Weinberg DN, Papillon-Cavanagh S, Chen H, Yue Y, Chen X, Rajagopalan KN, Horth C, McGuire JT, Xu X, Nikbakht H, Lemiesz AE, Marchione DM, Marunde MR, Meiners MJ, Cheek MA, Keogh MC, Bareke E, Djedid A, Harutyunyan AS, Jabado N, Garcia BA, Li H, Allis CD, Majewski J, Lu C Nature 2019 Sep 573 281-286

Research

Respiratory viral infection
Energy regulation
Immune response
Leptin signaling

Clinical Focus

Medical Critical Care

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