- American Society of Clinical Oncology
- American Society of Hematology
- American Society of Pediatric Hematology/Oncology
- Children’s Oncology Group
Kathleen Ludwig, M.D.
- Pediatrics - Hematology-Oncology
- Pediatric Hematology/Oncology
Biography
Kathleen Ludwig, M.D., is an Associate Professor in the Department of Pediatrics at UT Southwestern Medical Center. She specializes in pediatric hematology and oncology.
Dr. Ludwig earned her medical degree at the Loyola University Chicago Stritch School of Medicine. She completed her residency in pediatrics at UT Southwestern, where she also received advanced training through a fellowship in pediatric hematology and oncology.
Certified by the American Board of Pediatrics, she joined the UT Southwestern faculty in 2015.
Dr. Ludwig’s clinical and research interests include leukemia and vascular anomalies. She is a member of the American Society of Clinical Oncology, the American Society of Hematology, the American Society of Pediatric Hematology/Oncology, and the Children’s Oncology Group.
Education & Training
- Medical School - Loyola University Chicago Stritch School of Medicine (2005-2009)
- Residency - UT Southwestern/Children's Medical Center (2009-2012), Pediatrics
- Fellowship - UT Southwestern/Children's Medical Center (2012-2015), Pediatric Hematology/oncology
Professional Associations & Affiliations
Honors & Awards
- D Magazine Best Doctor 2022-2025
- D Magazine Best Pediatric Specialist 2021
- Best Basic Science Award 2014, Annual Surgical Research Forum, UT Southwestern
- Best Poster Award 2015, UT Southwestern Pediatric Fellow's Research Symposium
- Above-and-Beyond Recognition for Excellence 2010, UT Southwestern Pediatric Residency Program
Books & Publications
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Publications
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Interplay between Genetic Ancestry, Self-reported Race and Ethnicity, and Clinical Factors in Pediatric Acute Lymphoblastic Leukemia: A REDIAL Consortium Report
Kore P, Geris JM, Leon-Camarena M, Castellanos MI, Taylor OA, Garcia-Morales V, Brown AL, Sok P, Schraw JM, Huynh V, Ludwig KF, Klesse LJ, Pruitt SL, Hughes AE, Tien K, Heym KM, Griffin T, Erana R, Bernini JC, Gramatges MM, Atkinson EG, Lupo PJ, Scheurer ME, Rabin KR Cancer Epidemiology Biomarkers and Prevention 2026 May 35 710-717 -
A Case Series of Peritoneal Mesothelioma in Pediatric Patients
Merritt A, Ludwig K, Polanco PM, Sengupta A, Sadanand A Journal of Pediatric Hematology/Oncology 2026 Mar 48 e105-e108 -
An analysis of diagnostic metabolomic profiles associated with hepatotoxicity during childhood ALL induction therapy
Mason EJ, Crain AM, Scheurer ME, Lupo PJ, Rabin KR, Taylor OA, Roberts M, Woodhouse JP, Chavana A, Ludwig K, Klesse L, Heym K, Griffin T, Erana R, Bernini JC, Gramatges MM, Yi JS, Pruitt SL, Bernhardt MB, Zhu H, Mittelman SD, Huynh V, Orgel E, Schraw JM, Brown AL Blood Advances 2025 Nov 9 5802-5810 -
Prediction of methotrexate neurotoxicity using clinical, sociodemographic, and area-based information in children with acute lymphoblastic leukemia
Harris RD, Taylor OA, Gramatges MM, Hughes AE, Zobeck M, Pruitt S, Bernhardt MB, Chavana A, Huynh V, Ludwig K, Klesse L, Heym K, Griffin T, Erana R, Bernini JC, Choi A, Ohno Y, Richard MA, Morrison AC, Chen H, Yu B, Lupo PJ, Rabin KR, Scheurer ME, Brown AL Oncologist 2025 Jun 30 -
Larotrectinib for Newly Diagnosed Infantile Fibrosarcoma and Other Pediatric NTRK Fusion-Positive Solid Tumors (Children's Oncology Group ADVL1823)
Laetsch TW, Voss S, Ludwig K, Hall D, Barkauskas DA, Dubois SG, Ronan J, Rudzinski ER, Memken A, Robinson K, Sorger J, Reid JM, Bhatla T, Crompton BD, Church AJ, Fox E, Weigel BJ Journal of Clinical Oncology 2025 Apr 43 1188-1197 -
Evaluation of methotrexate Pharmacogenomic variation to predict acute neurotoxicity in children with acute lymphoblastic leukemia
Harris RD, Taylor OA, Gramatges MM, Hughes AE, Zobeck M, Pruitt S, Bernhardt MB, Chavana A, Huynh V, Ludwig K, Klesse L, Heym K, Griffin T, Erana R, Bernini JC, Choi A, Ohno Y, Richard MA, Morrison AC, Chen H, Yu B, Lupo PJ, Rabin K, Scheurer ME, Brown AL Pharmacotherapy 2025 Jan 45 4-11 -
Phase II Study of Samotolisib in Children and Young Adults With Tumors Harboring Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Pathway Alterations: Pediatric MATCH APEC1621D
Laetsch TW, Ludwig K, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey B, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Mhlanga J, Fox E, Weigel BJ, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW JCO Precision Oncology 2024 Sep 8 -
Early therapy with sirolimus reduces size of a large solid renal mass but not seizure activity in an infant with tuberous sclerosis
Hani SB, Artunduaga M, Ludwig K, Bissler JJ, Wolf MT Journal of Nephrology 2024 Jan 37 203-205 -
Genomic heterogeneity within B/T mixed phenotype acute leukemia in a context of an immunophenotype
Zheng R, Fuda F, Gagan JR, Weinberg OK, Koduru P, Cantu M, Ludwig K, Truscott JM, Collins R, Chung S, Madanat YF, Chen W Leukemia Research Reports 2024 Jan 21 -
Recent progress in the treatment of cancer in children
Butler E, Ludwig K, Pacenta HL, Klesse LJ, Watt TC, Laetsch TW CA Cancer Journal for Clinicians 2021 Jul 71 315-332 -
Giant congenital melanocytic nevus treated with trametinib
Mir A, Agim NG, Kane AA, Josephs SC, Park JY, Ludwig K Pediatrics 2019 Mar 143 -
Small-molecule inhibition of Axl targets tumor immune suppression and enhances chemotherapy in pancreatic cancer
Ludwig KF, Du W, Sorrelle NB, Wnuk-Lipinska K, Topalovski M, Toombs JE, Cruz VH, Yabuuchi S, Rajeshkumar NV, Maitra A, Lorens JB, Brekken RA Cancer research 2018 Jan 78 246-255 -
A new case and review of chylothorax in generalized lymphatic anomaly and gorham-stout disease
Ludwig KF, Slone T, Cederberg KB, Silva AT, Dellinger MT Lymphology 2016 49 73-84 -
Warfarin blocks Gas6-mediated Axl activation required for pancreatic cancer epithelial plasticity and metastasis
Kirane A, Ludwig KF, Sorrelle N, Haaland G, Sandal T, Ranaweera R, Toombs JE, Wang M, Dineen SP, Micklem D, Dellinger MT, Lorens JB, Brekken RA Cancer research 2015 Sep 75 3699-3705
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Interplay between Genetic Ancestry, Self-reported Race and Ethnicity, and Clinical Factors in Pediatric Acute Lymphoblastic Leukemia: A REDIAL Consortium Report
Research
- Leukemia
- Vascular Anomalies
Clinical Focus
- Pediatric Hematology/Oncology
Children's Medical Center of Dallas
1935 Medical District DriveDallas, Texas 75235 214-730-5437 Directions to Children's Medical Center of Dallas at Children's Medical Center of Dallas, Dallas