- Fellowship - UT Southwestern Medical Center (1995-1997), Cytogenetics
- Fellowship - UT Southwestern Medical Center (1994-1995), Hematopathology
- Residency - UT Southwestern Medical Center (1992-1994), Pathology
- Internship - UT Southwestern Medical Center (1991-1992), Pathology
- Medical School - UT Southwestern Medical School (1986-1991)
Kathleen Wilson, M.D.
Director, Cytogenomic Microarray Analysis Laboratory; Chair, UT Southwestern Medical School Admissions Committee; Co-director, Medical School Genetics Course
- Pathology
Biography
Dr. Kathleen S. Wilson is the Director of the Cytogenomic Microarray Analysis (CMA) laboratory in the Genetic Diagnostics Laboratories. She established the first CMA Laboratory for patient diagnostics in North Texas in 2008, bringing this technologically advanced form of high resolution chromosome analysis for clinical care to U.T. Southwestern and the North Texas region. She completed her undergraduate education at Amherst College and graduated with honors in 1986. She received her medical degree in 1991 from The University of Texas Southwestern Medical Center at Dallas. She subsequently completed pathology residency and genetics fellowship training also at UT Southwestern.
Dr. Wilson is a faculty member in the Department of Pathology and the McDermott (Genetics) Center for Human Growth and Development. She is board-certified by the American Board of Pathology (ABP) in Clinical Pathology and the American Board of Medical Genetics (ABMG) in Clinical Cytogenetics. She is also a fellow of the College of American Pathologists (CAP) and the American College of Medical Genetics (ACMG).
She has served on the Cytogenetics Resource Committee (CyRC) of the CAP and ACMG for over a decade and was involved in setting national policy for cytogenetics and molecular cytogenomics by developing accreditation guidelines and issuing proficiency testing. She has served as chair of the Economics of Genetic Services Committee for ACMG and has also been an active participant nationally in policy related to reimbursement for high complexity genetic testing. She is currently involved in multiple medical school administrative and educational activities in her roles as Chair of the UT Southwestern Medical School Admissions Committee and Co-Director of the Medical Student Genetics Course.
Dr. Wilson’s interest and experience in molecular genetics and genomics have been longstanding with recent publications in The Journal of Pediatric Hematology Oncology and Pediatric and Developmental Pathology, and book chapters in Abeloff: Clinical Oncology, 4th ed., Clinical Laboratory Hematology, 3rd ed. and Rosenberg’s Molecular and Genetic Basis of Neurological and Psychiatric Disease, 5th ed.
Dr. Wilson has won teaching awards and has been actively involved in the teaching and mentorship of medical and graduate students, house staff, and junior faculty for over twenty-five years.
Education & Training
Professional Associations & Affiliations
- Texas Medical Association (1991)
- Dallas County Medical Society (1991)
- American Medical Association (1991)
- College of American Pathologists (1993)
- American College of Medical Genetics (2002)
Honors & Awards
- Guide to America's Top Pathologists 2007, Consumers' Research Council of America (2007-present)
- Outstanding Teacher in Pathology 2007, UT Southwestern Class of 2009
- Small Group Teaching Award in Pathology 2007, UT Southwestern Class of 2009
- Doximity Recognition 2017, Top M.D. by Consumers Checkbook
- Outstanding Teacher in Genetics: Pre-Clinical Teaching Award 2012, UT Southwestern Class of 2015
- Aston L. Clarke Research Fellowship 1985, UT Southwestern Medical Center at Dallas
- Amherst College: Graduation with Honors 1986, B.A., magna cum laude
- Guide to America's Top Physicians 2004, Consumers' Research Council of America (2004-present)
- Favorite Teacher Recognition in Pathology 2005, UT Southwestern Class of 2007
Books & Publications
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Publications
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Cytogenetic and Cytogenomic Microarray Characterization of Chromothripsis in Chromosome 8 Affecting MOZ/NCOA2 (TIF2), FGFR1, RUNX1T1, and RUNX1 in a Pediatric Acute Myeloid Leukemia.
Koduru PR, Wilson K, Wen J, Garcia R, Patel S, Monaghan SA Journal of pediatric hematology/oncology 2017 Jan -
JAK-STAT6 Pathway Inhibitors Block Eotaxin-3 Secretion by Epithelial Cells and Fibroblasts from Esophageal Eosinophilia Patients: Promising Agents to Improve Inflammation and Prevent Fibrosis in EoE.
Cheng E, Zhang X, Wilson KS, Wang DH, Park JY, Huo X, Yu C, Zhang Q, Spechler SJ, Souza RF PloS one 2016 11 6 e0157376 -
Novel r(2)(p25q31) Cytogenetic Abnormality in a Pediatric Patient With Acute Leukemia of Ambiguous Lineage.
Kim J, Bu L, Koduru PR, Wilson KS, Fuda FS, Kumar KR, Timmons CF, Slone TL, Luu HS Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2014 Dec -
Therapy-induced Secondary Acute Myeloid Leukemia With t(11;19)(q23;p13.1) in a Pediatric Patient With Relapsed Acute Promyelocytic Leukemia.
Dang DN, Morris HD, Feusner JH, Koduru P, Wilson K, Timmons CF, Cavalier M, Luu HS Journal of pediatric hematology/oncology 2014 Jun -
Response to Mariani Et al.: A second report of PARK2 duplication and developmental delay.
Scheuerle AE, Wilson KS American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2013 Jul 162 5 484 -
The clinical consequences of hemizygosity across 2 MB of 10q23 are restricted to Cowden syndrome.
Lewis CM, Bu D, Sarode V, Robinson L, Wilson KS, Viscusi RK, Eng C, Euhus DM Breast cancer research and treatment 2012 Dec 136 3 911-8 -
High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis.
Paulson V, Chandler G, Rakheja D, Galindo RL, Wilson K, Amatruda JF, Cameron S Genes, chromosomes & cancer 2011 Jun 50 6 397-408 -
PARK2 copy number aberrations in two children presenting with autism spectrum disorder: Further support of an association and possible evidence for a new microdeletion/microduplication syndrome.
Scheuerle A and Wilson K. Am J Med Genet Part B Neuropsychiatr Genet 2011 156B 413-420. -
High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis.
Paulson V, Chandler G, Rakheja D, Galindo R, Wilson K, Amatruda JF, Cameron S. Genes Chromosom Cancer 2011 50 397-408. -
College of American Pathologists/American College of Medical Genetics proficiency testing for constitutional cytogenomic microarray analysis.
Brothman AR, Dolan MM, Goodman BK, Park JP, Persons DL, Saxe DF, Tepperberg JH, Tsuchiya KD, Van Dyke DL, Wilson KS, Wolff DJ, Theil KS. Genet in Med 2011 13 765-769. -
The interface of Medicare coverage decision-making and emerging molecular-based laboratory testing.
Burken MI, Wilson KS, Heller K, Pratt VM, Schoonmaker MM, Seifter E. Genet in Med 2009 11 225-231. -
A bcr3/short form PML/RARα transcript in an acute promyelocytic leukemia resulted from a derivative chromosome 17 due to submicroscopic insertion of PML gene into RARα locus.
Wang H-Y, Ding J, Vasef MA, Wilson KS. Am J Clin Path 2009 131 64-71. -
An extranodal nasal natural killer/T-cell lymphooma with isochromosome 7q10 as the sole cytogenetic aberration was initially diagnosed via bone marrow biopsy.
Wang H-Y, Wilson KS, McKenna RW, Karandikar N, Xu Y. Arch Pathol Lab Med 2007 131 1709-1714. -
HER-2 fluorescence in situ hybridization: results from the survey program of the College of American Pathologists.
Persons DL, Tubbs RR, Cooley LD, Dewald GW, Dowling PK, Du E, Mascarello JT, Rao KW, Wilson KS, Wolff DJ, Habegger-Vance G. Arch Pathol Lab Med 2006 130 325-331. -
Immunophenotypic identification of acute myeloid leukemia with monocytic differentiation.
Xu Y, McKenna RW, Wilson KS, Karandikar NJ, Schultz RA, Kroft SH. Leukemia 2006 20 1321-1324. -
Chronic myelogenous leukemia [review].
Willis MS and Wilson KS. Lab Med 2002 33 203-207. -
Primary effusion lymphomas (PEL) exhibit complex and recurrent cytogenetic abnormalities.
Wilson KS, McKenna RW, Kroft SH, Dawson DB, Ansari Q, Schneider NR. Br J Haematol 2002 116 113-121.
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Cytogenetic and Cytogenomic Microarray Characterization of Chromothripsis in Chromosome 8 Affecting MOZ/NCOA2 (TIF2), FGFR1, RUNX1T1, and RUNX1 in a Pediatric Acute Myeloid Leukemia.
Research
- My research interests are focused on the clinical utilization of multiple genetic diagnostic technologies (next generation sequencing, cytogenomic microarray analysis, fluorescence in situ hybridization and conventional cytogenetics) in an integrated approach to elucidate the pathogenetic events of both constitutional and acquired (neoplastic) disorders.