Khashayar Sakhaee, M.D.

Laura Kim Pak Professorship in Mineral Metabolism Research
BeautiControl Cosmetics Inc. Professorship in Mineral Metabolism and Osteoporosis

Internal Medicine - Mineral Metabolism
Osteoporosis
Kidney Stones

New Patient Appointment Accepting Virtual Visits or 214-645-2870

Biography

Khashayar Sakhaee, M.D., is a Professor in the Department of Internal Medicine and Chief of the Division of Mineral Metabolism at UT Southwestern Medical Center. He specializes in metabolic bone disease (osteoporosis, osteomalacia, Paget’s disease of the bone, metabolic bone disorders resulting from chronic kidney disease), magnesium disorders (hypomagnesemia, hypermagnesemia), phosphate disorders (hyperphosphatemia, hypophosphatemia), and calcium disorders (hypercalcemia, hypocalcemia).

Dr. Sakhaee earned his medical degree at Pahlavi University Medical School in Iran, where he also performed a residency in internal medicine. After performing a separate residency at University Hospitals Cleveland Medical Center, he received advanced training in nephrology through a fellowship at UT Health Science Center at Dallas.

He joined the UT Southwestern faculty in 1982.

Dr. Sakhaee is Director of the Mineral Metabolism Clinic at Parkland Memorial Hospital and a member of the Ambulatory High-Performance Team for the Parkland Health & Hospital System. At UT Southwestern, he holds the Laura Kim Pak Professorship in Mineral Metabolism Research, and he is an active participant in the Clinical Operations Work Group Meeting, among other roles.

His research interests include uric acid stones, post-renal transplantation hypophosphatemia, and osteoporosis.

An editorial board member of the journal Urolithiasis, Dr. Sakhaee has published countless academic articles and delivered a number of international, national, and regional invited lectures.

He is a member of the National Kidney Foundation, the American Urological Association, and the Dallas County Medical Society, among many other professional organizations.

Education & Training

Fellowship - UT Southwestern Medical Center (1977-1979), Nephrology
Residency - University Hospitals of Cleveland (1976-1977), Internal Medicine
Internship/Residency - Pahlavi University Medical School (1972-1976), Internal Medicine
Medical School - Pahlavi University Medical School

Professional Associations & Affiliations

National Kidney Foundation
Dallas County Medical Society
American Urological Association
Association for Patient-Oriented Research
Endocrine Society
American Society for Bone and Mineral Research
International Society of Nephrology
American Society of Nephrology
American Federation for Medical Research

Honors & Awards

Laura Kim Pak Professorship in Mineral Metabolism Research 2010-2020, UT Southwestern Medical Center
BeautiControl Cosmetics Inc. Professorship in Mineral Metabolism and Osteoporosis 1994-2020, UT Southwestern Medical Center
Best Doctors in America 2005-2020, Nephrology, Mineral Metabolism
Best Reviewer Award 2012, American Urological Association—Journal of Urology
America’s Top Physicians 2007-2008, Consumer’s Research Council of America
Internal Medicine House Staff Outstanding Teacher Award 1995-1996, UT Southwestern Medical Center

Books & Publications

Books
- Uric Acid Stones: Epidemiology, Pathophysiology and Treatment in Kidney Stones Medical and Surgical Management. (Eds: Coe, F.L, Worcester, E.M., Evan, A.P, Lingeman, J.E.) 2nd Edition
  Sakhaee, K. (2020), Jaypee Brothers Medical Publisher
- Renal stone disease, hypercalciuria, and Osteoporosis: use of thiazides and alkali for osteoporosis in Marcus and Feldman’s Osteoporosis. (Eds: Dempster, D., Cauley, J., Bouxsein, M., and Cosman, F.), Fifth Edition, Volume 2
  Sakhaee, K., Maalouf, N.M., Academic Press
- Urolithiasis in Brenner and Rector’s the Kidney. (Eds; Yu, A., Chertow, G, Marsden, Luyckx, V., Philip, M., Skorecki, K., and Taal, M.), Eleventh Edition
  Sakhaee K., Moe OW. (2019), Philadelphia, Elseveir
- Medical Management of Nephrocalcinosis and Nephrolithiasis in Oxford Textbook of Clinical Nephrology (Ed. Marc E. De Broe). Fourth Edition
  Sinnott B., Maalouf N., Sakhaee K. Moe OW (2015), Oxford University Press
- Urolithiasis in Brenner and Rector’s the Kidney. (Eds; Skorski, K., Chertow, G, Marsden, P., Taal, M., and Yu, M.), Tenth Edition
  Sakhaee K. Moe OW (2015), Philadelphia, Elseveir
- Uric Acid Nephrolithiasis: Uric Acid or Urine pH? in Practical Controversies in Medical Management of Stone Disease. (Eds) Pearle MS, Nakada SY
  Sakhaee K. (2014), New York, Springer Publishing, Springer Science + Business Media
- Uric Acid Nephrolithiasis: Basic and Clinical Aspects in Urolithiasis: Basic Science and Clinical Practice. (Eds) Talati, J, Tiselius HG, Albala D, Ye Z
  Sakhaee K. (2012), London, Springer Publishing, Springer-London
- Medical Management: Uric Acid and Cystine Stones in Urinary Tract Stone Disease. (Eds) Rao NP, Preminger G, Kavanaugh J
  Sakhaee K. (2011), London, BC Decker Publishing, Springer-Verlag
Publications
- Metabolic syndrome and uric acid nephrolithiasis
  Sakhaee K, NM Maalouf Sem Nephrol 2008 28 174-180
- Nephrolithiasis as a systemic disorder
  Sakhaee K Curr Opin Nephrol Hypertens 2008 17 304-309
- The role of RANK/RANKL/OPG: Clinical implications
  Vega D, NM Maalouf, and K Sakhaee J Clin Endocrinol Metab 2007 92 4514-4521
- Increased propensity for calcium phosphate kidney stones with topiramate use
  Vega D, NM Maalouf, and K Sakhaee Expert Opin Drug Saf 2007 6 547-557
- Osteoporosis following solid organ transplantation
  Vega D, K Sakhaee Future Rheumatol 2007 2 341-345
- Low Urine pH: A Novel Feature of the Metabolic Syndrome
  NM Maalouf, MA Cameron, OW Moe, B Adams-Huet, and K Sakhaee Clin J Am Soc Nephrol 2007 5 883-888
- Urine composition in Type 2 Diabetes: Predisposition to Uric Acid Nephrolithiasis
  Cameron MA, NM Maalouf, B Adams-Huet B, OW Moe, K Sakhaee J Am Soc Nephrol 2006 17 1422-1428
- Effects of potassium alkali and calcium supplementation on bone turnover in postmenopausal women
  Sakhaee K, NM Maalouf, SA Abrams and CYC Pak J Clin Endocrinol Metab 2005 90 3528-3533
- Effect of dietary modification on urinary stone risk factors
  Pak CYC, CV Odvina, M Pearle, K Sakhaee, R Peterson, JR Poindexter and L Brinkley Kidney Int 2005 68 2264-2273
- Pathophysiologic basis for normouricosuric uric acid nephrolithiasis
  Sakhaee K, Adams-Huet B, Moe OW, Pak CYC Kid. Int. 2002 62 971-979

Research

Uric Acid Stones
Post-Renal Transplantation
Osteoporosis
Nephrolithiasis
Bone Loss

Clinical Focus

Osteoporosis
Kidney Stones
Chronic Kidney Disease—Metabolic Bone Disease
Osteomalacia
Paget’s Disease of the Bone
Management of Magnesium Disorders (Hypomagnesemia, Hypermagnesemia)
Management of Phosphate Disorders (Hyperphosphatemia, Hypophosphatemia)
Management of Calcium Disorders (Hypercalcemia, Hypocalcemia)