Kurt Kleinschmidt, M.D.

Emergency Medicine

Biography

Kurt C. Kleinschmidt, M.D., FACMT, DABAM is a Professor of Emergency Medicine at the University of Texas Southwestern Medical Center in Dallas, Texas. He is the Division Chief and Program Director for Medical Toxicology. He also works with Parkland Health and Hospital System Maternal Fetal Medicine in optimizing the care of pregnant women who have substance use disorders. His areas of interest include drugs of abuse and addiction and withdrawal issues. He graduated from the University of South Florida College of Medicine in 1986, completed his Emergency Medicine residency at Madigan Army Medical Center in 1990, and finished a clinical fellowship in Toxicology at the University of Texas Southwestern Medical Center in 1999. He is board certified in Emergency Medicine, Medical Toxicology, and Addiction Medicine. In 2016, he became the Medical Director of the Perinatal Intervention Program with the Department of Obstetrics and Gynecology; providing addiction care to pregnant patients who have substance use disorders.

In 2018, Dr. Kleinschmidt received UT Southwestern's Program Development Award.

Education & Training

Medical School - University of South Florida College of Medicine (1982-1986)
Internship - Letterman Army Medical Center (1986-1987), Internal Medicine
Fellowship - UT Southwestern Medical Center (1994-1999), Toxicology
Residency - Madigan Army Medical Center (1987-1990), Emergency Medicine

Professional Associations & Affiliations

American Academy Clinical Toxicology (2002), Largest physician and non-physician toxicology society in North America
American Society of Addiction Medicine (2015), Largest physician society focused on addiction
American College of Medical Toxicology (2002), Largest Physician Medical Toxicologist society in North America

Honors & Awards

Program Development Award – UT Southwestern 2018
Teaching Excellence Award 2002, From the Parkland Emergency Medicine Residents 2001/2002
Teaching Excellence Award 2015 2015, UTSW Class of 2017 award for being a top faculty
American College of Medical Toxicology (ACMT) - Education Award 2015, Award from ACMT for lifetime contributions to the educational pursuits of medical toxicology

Books & Publications

Books
- Hydrocarbons in Textbook of Critical Care Medicine, 6th Ed
  Sharma K and Kleinschmidt K. (2011), Elsevier
- Toxic Inhalations in Textbook of Critical Care Medicine, 6th Ed. ; Editor Jean-Louis Vincent
  Schwarz E and Kleinschmidt K (2011), Elsevier
- Toxicology in the Critical Care Unit in The Evidence Based Practice of Critical Care. Editors: Deutschman & Neligan
  Weier A and Kleinschmidt K. (2010), Saunders Elsevier
- Adult Education Principles. in Practical Teaching in Emergency Medicine, 2nd Ed.
  O'Connell, Ellen and Kleinschmidt Kurt (2012), Wiley-Blackwell Publishing
- Hydrocarbons and Halogenated Hydrocarbons in Critical Care Toxicology: the Diagnosis and Management of the Critically Poisoned Patient
  27. Furmaga J, Kleinschmidt K, Sharma K (2016), Springer
- Biochemical and Metabolic Principles in Goldfrank?s Toxicologic Emergencies
  Kleinschmidt KC and Delaney KD (2010), New York, McGraw-Hill
Publications
- Cottonmouth snake bites reported to the ToxIC North American snakebite registry 2013-2017.
  Domanski K, Kleinschmidt KC, Greene S, Ruha AM, Berbata V, Onisko N, Campleman S, Brent J, Wax P, Clinical toxicology (Philadelphia, Pa.) 2019 Jun 1-5
- Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation.
  Freiermuth CE, Lavonas EJ, Anderson VE, Kleinschmidt KC, Sharma K, Rapp-Olsson M, Gerardo C, The western journal of emergency medicine 2019 May 20 3 497-505
- The validity, reliability and minimal clinically important difference of the patient specific functional scale in snake envenomation.
  Gerardo CJ, Vissoci JRN, de Oliveira LP, Anderson VE, Quackenbush E, Lewis B, Rose SR, Greene S, Toschlog EA, Charlton NP, Mullins ME, Schwartz R, Denning D, Sharma K, Kleinschmidt K, Bush SP, Brandehoff NP, Lavonas EJ, PloS one 2019 14 3 e0213077
- Adverse Events in the Efficacy of Crotalidae Polyvalent Immune Fab Antivenom vs Placebo in Recovery from Copperhead Snakebite Trial.
  Mullins ME, Gerardo CJ, Bush SP, Rose SR, Greene S, Quackenbush EB, Lewis B, Anderson VE, Kleinschmidt KC, Schwarz RB, Charlton NP, Toschlog EA, Sharma K, Denning DA, Lavonas EJ Southern medical journal 2018 Dec 111 12 716-720
- Acute adverse events associated with the administration of Crotalidae polyvalent immune Fab antivenom within the North American Snakebite Registry.
  Kleinschmidt K, Ruha AM, Campleman S, Brent J, Wax P, Clinical toxicology (Philadelphia, Pa.) 2018 11 56 11 1115-1120
- Early administration of Fab antivenom resulted in faster limb recovery in copperhead snake envenomation patients.
  Anderson VE, Gerardo CJ, Rapp-Olsson M, Bush SP, Mullins ME, Greene S, Toschlog EA, Quackenbush E, Rose SR, Schwartz RB, Charlton NP, Lewis B, Kleinschmidt KC, Sharma K, Lavonas EJ Clinical toxicology (Philadelphia, Pa.) 2018 Sep 1-6
- Epidemiology and clinical outcomes of snakebite in the elderly: a ToxIC database study^.
  Spyres MB, Ruha AM, Kleinschmidt K, Vohra R, Smith E, Padilla-Jones A, Clinical toxicology (Philadelphia, Pa.) 2018 02 56 2 108-112
- Differences Between Snakebites with Concomitant Use of Alcohol or Drugs and Single Snakebites.
  Schulte J, Kleinschmidt KC, Domanski K, Smith EA, Haynes A, Roth B Southern medical journal 2018 Feb 111 2 113-117
- The Epidemiology, Clinical Course, and Management of Snakebites in the North American Snakebite Registry.
  Ruha AM, Kleinschmidt KC, Greene S, Spyres MB, Brent J, Wax P, Padilla-Jones A, Campleman S Journal of medical toxicology : official journal of the American College of Medical Toxicology 2017 Oct
- U-47700: A Clinical Review of the Literature.
  Rambaran KA, Fleming SW, An J, Burkhart S, Furmaga J, Kleinschmidt KC, Spiekerman AM, Alzghari SK The Journal of emergency medicine 2017 Sep
- A little "dab" will do ya' in: a case report of neuro-and cardiotoxicity following use of cannabis concentrates.
  Rickner SS, Cao D, Kleinschmidt K, Fleming S Clinical toxicology (Philadelphia, Pa.) 2017 Jun 1-3
- The Efficacy of Crotalidae Polyvalent Immune Fab (Ovine) Antivenom Versus Placebo Plus Optional Rescue Therapy on Recovery From Copperhead Snake Envenomation: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial.
  Gerardo CJ, Quackenbush E, Lewis B, Rose SR, Greene S, Toschlog EA, Charlton NP, Mullins ME, Schwartz R, Denning D, Sharma K, Kleinschmidt K, Bush SP, Ryan S, Gasior M, Anderson VE, Lavonas EJ Annals of emergency medicine 2017 Jun
- Analysis of U-47700, a Novel Synthetic Opioid, in Human Urine by LC-MS-MS and LC-QToF.
  Fleming SW, Cooley JC, Johnson L, Frazee CC, Domanski K, Kleinschmidt K, Garg U Journal of analytical toxicology 2017 Apr 41 3 173-180
- Childhood Victims of Snakebites: 2000-2013.
  Schulte J, Domanski K, Smith EA, Menendez A, Kleinschmidt KC, Roth BA Pediatrics 2016 Nov 138 5
- Two cases of intoxication with new synthetic opioid, U-47700.
  Domanski K, Kleinschmidt KC, Schulte JM, Fleming S, Frazee C, Menendez A, Tavakoli K Clinical toxicology (Philadelphia, Pa.) 2016 Jul 1-5
- Missed opportunities?: an evaluation of potentially preventable poisoning deaths.
  Srisuma S, Cao D, Kleinschmidt K, Heffner AC, Lavonas EJ Clinical toxicology (Philadelphia, Pa.) 2016 Mar 1-6
- Comparison of Unintentional Exposures to Codeine and Hydrocodone Reported to Texas Poison Centers.
  Day L, Kleinschmidt K, Forrester MB, Feng SY The Journal of emergency medicine 2016 Feb
- Trends in analgesic exposures reported to Texas Poison Centers following increased regulation of hydrocodone.
  Haynes A, Kleinschmidt K, Forrester MB, Young A Clinical toxicology (Philadelphia, Pa.) 2016 Feb 1-7
- Cluster of Acute Toxicity from Ingestion of Synthetic Cannabinoid-Laced Brownies.
  Obafemi AI, Kleinschmidt K, Goto C, Fout D Journal of medical toxicology : official journal of the American College of Medical Toxicology 2015 May
- N-Acetylcysteine (NAC)-Induced Hyponatremia Caused by an Electronic Medical Record (EMR) Order Error.
  Furmaga J, Wax P, Kleinschmidt K Journal of medical toxicology : official journal of the American College of Medical Toxicology 2015 Jan
- Electronic Cigarette Exposures Reported to Texas Poison Centers.
  Ordonez JE, Kleinschmidt KC, Forrester MB Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2014 Oct
- Diphenhydramine's role in death investigations: an examination of diphenhydramine prevalence in 2 US geographical areas.
  Botch-Jones SR, Johnson R, Kleinschmidt K, Bashaw S, Ordonez J The American journal of forensic medicine and pathology 2014 Sep 35 3 181-5
- Emergency department patients with acute severe hypertension: a comparison of those admitted versus discharged in studying the treatment of acute hypertension registry.
  Kleinschmidt K, Levy P, Wyman A, Dasta JF, Mayer SA, Amin A, Pollack C, Shorr AF, Froehlich JB, Multz AS, Peacock WF Critical pathways in cardiology 2014 Jun 13 2 66-72
- Multiple Poisonings with Sodium Azide at a Local Restaurant.
  Schwarz ES, Wax PM, Kleinschmidt KC, Sharma K, Chung WM, Cantu G, Spargo E, Todd E The Journal of emergency medicine 2013 Nov
- Successful management of olanzapine-induced anticholinergic agitation and delirium with a continuous intravenous infusion of physostigmine in a pediatric patient.
  Hail SL, Obafemi A, Kleinschmidt KC Clinical toxicology (Philadelphia, Pa.) 2013 Mar 51 3 162-6
- Guide to Clinical Trials in Thrombosis Management: Year 2002-2003 Update
  Kleinschmidt K, Miller A, Pollack C, Bosker G. 2002 2nd Ed
- Acute Coronary Syndromes: Clinical Pathophysiology
  Kleinschmidt K Adult and Pediatric Emergency Medicine 2002 2nd ed 869-882
- Pharmacology of Low Molecular Weight Heparins
  Kleinschmidt KC, Charles RC Emergency Medicine Clinics of North America November 2001 19(4) 1025-1049
- Acute Myocardial Infarction: Optimizing selection of reperfusion therapies in the coronary care unit and emergency department
  Brady WJ, Kleinschmidt K, Bosker G Emergency Medicine Consensus Reports September 2001 1-17
- Fluids and Electrolytes in Toxicology
  Kleinschmidt KC, Delaney KD Clinical Toxicology 2000 1st Ed. Saunders
- Opioids
  Kleinschmidt KC, Wainscott MP, Ford M Clinical Toxicology 2000 1st Ed

Research

Drugs of Abuse
Addiction Medicine
Snakebites