- Fellowship - Ohio State University Hospital (2005-2007), Infectious Diseases
- Graduate School - The Ohio State University College of Public Health (2007-2009)
- Other Post Graduate Training - Ohio State University College of Public Health (2007-2009)
- Residency - Mount Carmel Medical Center (2002-2005), Internal Medicine
- Medical School - Sri Venkateswara University (1992-1999)
Madhuri Sopirala, M.D.
- Internal Medicine - Infectious Diseases and Geographic Medicine
Biography
Madhuri Sopirala, M.D., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of its Division of Infectious Diseases and Geographic Medicine. She serves as Director of Infection Prevention at Parkland Health & Hospital System.
Dr. Sopirala received her medical education at Sri Venkatesvara Medical College in Andhra Pradesh, India. She obtained internal medicine residency training at Mount Carmel Medical Center in Columbus, Ohio, followed by advanced training through a fellowship program in infectious diseases at The Ohio State University Medical Center, where she also earned a master's of public health degree in clinical investigation.
Board certified in internal medicine and in infectious diseases, she joined the UT Southwestern faculty in 2017 as the Chief of Infection Prevention at the VA North Texas Healthcare System. Previously, she served for five years as the Associate Chief of the Department of Clinical Epidemiology/Infection Prevention and Control at the Ohio State University Medical Center, and for six years as the Chief of IPC at the University of Cincinnati Healthcare System, where she successfully led system-wide performance improvement in prevention of hospital-acquired infections (HAI), with particular expertise in central line associated blood stream infections. At both institutions, she implemented her signature program – Infection Control Link Nurse Program – which brought multiple disciplines together in infection prevention efforts for sustained improvements.
Much of her work in HAI prevention is documented in peer-reviewed publications. While at University of Cincinnati Healthcare System, she also served as the Chief of Antimicrobial Stewardship, implementing several innovative patient safety initiatives. As a result of her work in HAI reduction, she received an IMPACT award, granted to the most impactful physician in the health system from the medical directors at the University of Cincinnati. She was awarded a New Investigator award at the VAMC-North Texas for a novel study focused on the epidemiology of multidrug resistant Gram-negative colonization and infection. Her research interests focus on healthcare associated infections and multidrug resistant Gram-negative organisms.
Dr. Sopirala has mentored numerous fellows, residents and medical students throughout her career. Her work with the trainees has resulted in multiple peer reviewed publications. She is recognized as a leader in the field by national organizations and serves on the editorial boards for several reputed journals.
Education & Training
Professional Associations & Affiliations
- Society for Healthcare Epidemiology of America
- Society of Healthcare Epidemiology Long Term Care Interest Group
- Infectious Diseases Society of America
- American College of Physicians
Honors & Awards
- Fellow 2012, American College of Physicians
- Fellow 2016, Infectious Diseases Society of America
- Honorable mention for partnership in prevention - SHEA-APIC Partnership in Prevention Award 2010, Fifth Decennial International Conference on Healthcare-Associated Infections
- IMPACT award 2015, University of Cincinnati Medical Center
Books & Publications
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Books
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Lung Abscesses and Pleural Abscesses in Infectious Diseases Third Edition
Sopirala MM, Mangino, JE (2009), United Kingdom, Elsevier -
Tuberculosis in Treatment Strategies for Common Medical Problems Second Edition
Sopirala MM, Mangino, JE. (2009), United Kingdom, Elsevier
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Lung Abscesses and Pleural Abscesses in Infectious Diseases Third Edition
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Publications
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Central Line-Associated Bloodstream Infection Misclassifications - Rethinking the Centers for Disease Control and Prevention's Central Line-Associated Bloodstream Infection Definition and Its Implications
Sopirala MM, Estelle CD, Houston L Critical care medicine 2024 Mar 52 357-361 -
Investigation of the first reported outbreak of New Delhi metallo-β-lactamase-1-producing Pseudomonas aeruginosa in Texas
Sopirala MM, Hartless K, Reid S, Christie-Smith A, Fiveash J, Badejogbin A, Psenicka AO Antimicrobial Stewardship and Healthcare Epidemiology 2024 Jan 3 -
Effect of serious infectious threat response initiative (SITRI) during the coronavirus disease 2019 (COVID-19) pandemic at the Veterans Affairs North Texas Health Care System
Sopirala M, Hartless K, Reid S, Christie-Smith A, Fiveash J, Badejogbin A, Omoola I, Psenicka AO, Jandarov R, Kazadi I, Barriento R American Journal of Infection Control 2023 Sep 51 980-987 -
Build upon basics: An intervention utilizing safety huddles to achieve near-zero incidence of catheter associated urinary tract infection at a department of Veterans Affairs long-term care facility
Fiveash JM, Smith ML, Moore AK, Jandarov R, Sopirala MM American Journal of Infection Control 2021 Nov 49 1419-1422 -
Predisposition of COVID-19 patients to secondary infections: set in stone or subject to change?
Sopirala MM Current Opinion in Infectious Diseases 2021 Aug 34 357-364 -
Out of sight—out of mind: Impact of cascade reporting on antimicrobial usage
Liao S, Rhodes J, Jandarov R, DeVore Z, Sopirala MM Open Forum Infectious Diseases 2020 Feb 7 -
Impact of a change in surveillance definition on performance assessment of a catheter-associated urinary tract infection prevention program at a tertiary care medical center
Sopirala MM, Syed A, Jandarov R, Lewis M American Journal of Infection Control 2018 Jul 46 743-746 -
Effect of automated ultraviolet C–emitting device on decontamination of hospital rooms with and without real-time observation of terminal room disinfection
Penno K, Jandarov RA, Sopirala MM American Journal of Infection Control 2017 Nov 45 1208-1213 -
Does the Centers for Disease Control and Prevention's Ventilator-Associated Event Definition Unintentionally Contradict Its Antimicrobial Stewardship Initiative?
Sopirala MM Clinical Infectious Diseases 2017 Oct 65 1248-1249 -
Infection control link nurse program: An interdisciplinary approach in targeting health care-acquired infection
Sopirala MM, Yahle-Dunbar L, Smyer J, Wellington L, Dickman J, Zikri N, Martin J, Kulich P, Taylor D, Mekhjian H, Nash M, Mansfield J, Pancholi P, Howard M, Chase L, Brown S, Kipp K, Lefeld K, Myers A, Pan X, Mangino JE American Journal of Infection Control 2014 Apr 42 353-359 -
A quality improvement imperative: Achieving command over hospital acquired infections in intensive care units
Exline MC, Masood S, Sopirala MM 2014 Jan 76 1-20 -
Beyond the bundle - journey of a tertiary care medical intensive care unit to zero central line-associated bloodstream infections
Exline MC, Ali NA, Zikri N, Mangino JE, Torrence K, Vermillion B, St Clair J, Lustberg ME, Pancholi P, Sopirala MM Critical Care 2013 Mar 17 -
Sustained reduction of central line-associated bloodstream infections in an intensive care unit using a top-down and bottom-up approach
Sopirala MM, Smyer J, Fawley L, Mangino JE, Lustberg ME, Lu J, Chucta S, Crouser ED American Journal of Infection Control 2013 Feb 41 183-184 -
Effect of fever on hospital presentation, diagnosis, and treatment in patients with H1N1/09 influenza
Sopirala MM, Haas DM, Ali NA, Mangino JE, Pan X, Turner AN Journal of hospital medicine 2013 Jan 8 20-24 -
Carbapenem-hydrolyzing gram-negative bacteria: Current options for treatment and review of drugs in development
Abandeh FI, Drew ME, Sopirala MM Recent Patents on Anti-Infective Drug Discovery 2012 Apr 7 19-27 -
Assessment beyond central line bundle: Audits for line necessity in infected central lines in a surgical intensive care unit
Rotz S, Sopirala MM American Journal of Infection Control 2012 Feb 40 88-89 -
Acute leprosy in Ohio during treatment of HIV-AIDS
Sopirala MM, Wininger DA, Ayers LW New England Journal of Medicine 2011 Oct 365 1549-1551 -
An assessment of H1N1 influenza-associated acute respiratory distress syndrome severity after adjustment for treatment characteristics
Riscili BP, Anderson TB, Prescott HC, Exline MC, Sopirala MM, Phillips GS, Ali NA PloS one 2011 6 -
Synergy testing by etest, microdilution checkerboard, and time-kill methods for pan-drug-resistant Acinetobacter baumannii
Sopirala MM, Mangino JE, Gebreyes WA, Biller B, Bannerman T, Balada-Llasat JM, Pancholi P Antimicrobial agents and chemotherapy 2010 Nov 54 4678-4683 -
Lung abscesses and pleural abscesses
Sopirala MM, Mangino JE 2010 Jan 1 300-308 -
Multidrug-resistant Acinetobacter baumannii Pneumonia in Lung Transplant Recipients
Sopirala MM, Pope-Harman A, Nunley DR, Moffatt-Bruce S, Ross P, Martin SI Journal of Heart and Lung Transplantation 2008 Jul 27 804-807
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Central Line-Associated Bloodstream Infection Misclassifications - Rethinking the Centers for Disease Control and Prevention's Central Line-Associated Bloodstream Infection Definition and Its Implications
Research
- Process improvement
- Multidrug resistant Gram-negative organisms
- Healthcare acquired infections