Madhuri Sopirala, M.D.

Madhuri Sopirala, M.D.

  • Internal Medicine - Infectious Diseases and Geographic Medicine


Madhuri Sopirala, M.D., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of its Division of Infectious Diseases and Geographic Medicine. She serves as Director of Infection Prevention at Parkland Health & Hospital System. 

Dr. Sopirala received her medical education at Sri Venkatesvara Medical College in Andhra Pradesh, India. She obtained internal medicine residency training at Mount Carmel Medical Center in Columbus, Ohio, followed by advanced training through a fellowship program in infectious diseases at The Ohio State University Medical Center, where she also earned a master's of public health degree in clinical investigation.

Board certified in internal medicine and in infectious diseases, she joined the UT Southwestern faculty in 2017 as the Chief of Infection Prevention at the VA North Texas Healthcare System. Previously, she served for five years as the Associate Chief of the Department of Clinical Epidemiology/Infection Prevention and Control at the Ohio State University Medical Center, and for six years as the Chief of IPC at the University of Cincinnati Healthcare System, where she successfully led system-wide performance improvement in prevention of hospital-acquired infections (HAI), with particular expertise in central line associated blood stream infections. At both institutions, she implemented her signature program – Infection Control Link Nurse Program – which brought multiple disciplines together in infection prevention efforts for sustained improvements.

Much of her work in HAI prevention is documented in peer-reviewed publications. While at University of Cincinnati Healthcare System, she also served as the Chief of Antimicrobial Stewardship, implementing several innovative patient safety initiatives. As a result of her work in HAI reduction, she received an IMPACT award, granted to the most impactful physician in the health system from the medical directors at the University of Cincinnati. She was awarded a New Investigator award at the VAMC-North Texas for a novel study focused on the epidemiology of multidrug resistant Gram-negative colonization and infection. Her research interests focus on healthcare associated infections and multidrug resistant Gram-negative organisms.

Dr. Sopirala has mentored numerous fellows, residents and medical students throughout her career. Her work with the trainees has resulted in multiple peer reviewed publications. She is recognized as a leader in the field by national organizations and serves on the editorial boards for several reputed journals.

Education & Training
  • Fellowship - Ohio State University Hospital (2005-2007), Infectious Diseases
  • Graduate School - The Ohio State University College of Public Health (2007-2009)
  • Other Post Graduate Training - Ohio State University College of Public Health (2007-2009)
  • Residency - Mount Carmel Medical Center (2002-2005), Internal Medicine
  • Medical School - Sri Venkateswara University (1992-1999)
Professional Associations & Affiliations
  • Society for Healthcare Epidemiology of America
  • Society of Healthcare Epidemiology Long Term Care Interest Group
  • Infectious Diseases Society of America
  • American College of Physicians
Honors & Awards
  • Fellow 2012, American College of Physicians
  • Fellow 2016, Infectious Diseases Society of America
  • Honorable mention for partnership in prevention - SHEA-APIC Partnership in Prevention Award 2010, Fifth Decennial International Conference on Healthcare-Associated Infections
  • IMPACT award 2015, University of Cincinnati Medical Center
Books & Publications
  • Process improvement
  • Multidrug resistant Gram-negative organisms
  • Healthcare acquired infections