- Other Post Graduate Training - Ohio State University College of Public Health (2007-2009)
- Graduate School - The Ohio State University College of Public Health (2007-2009)
- Fellowship - Ohio State University Hospital (2005-2007), Infectious Diseases
- Residency - Mount Carmel Medical Center (2002-2005), Internal Medicine
- Medical School - Sri Venkateswara University (1992-1999)
Madhuri Sopirala, M.D.
- Internal Medicine - Infectious Diseases and Geographic Medicine
Madhuri Sopirala, M.D., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of its Division of Infectious Diseases and Geographic Medicine. She serves as Director of Infection Preventon at Parkland Health & Hospital System.
Dr. Sopirala received her medical education at Sri Venkatesvara Medical College in Andhra Pradesh, India. She obtained internal medicine residency training at Mount Carmel Medical Center in Columbus, Ohio, followed by advanced training through a fellowship program in infectious diseases at The Ohio State University Medical Center, where she also earned a master's of public health degree in clinical investigation.
Board certified in internal medicine and in infectious diseases, she joined the UT Southwestern faculty in 2017 as the Chief of Infection Prevention at the VA North Texas Healthcare System. Previously, she served for five years as the Associate Chief of the Department of Clinical Epidemiology/Infection Prevention and Control at the Ohio State University Medical Center, and for six years as the Chief of IPC at the University of Cincinnati Healthcare System, where she successfully led system-wide performance improvement in prevention of hospital-acquired infections (HAI), with particular expertise in central line associated blood stream infections. At both institutions, she implemented her signature program – Infection Control Link Nurse Program – which brought multiple disciplines together in infection prevention efforts for sustained improvements.
Much of her work in HAI prevention is documented in peer-reviewed publications. While at University of Cincinnati Healthcare System, she also served as the Chief of Antimicrobial Stewardship, implementing several innovative patient safety initiatives. As a result of her work in HAI reduction, she received an IMPACT award, granted to the most impactful physician in the health system from the medical directors at the University of Cincinnati. She was awarded a New Investigator award at the VAMC-North Texas for a novel study focused on the epidemiology of multidrug resistant Gram-negative colonization and infection. Her research interests focus on healthcare associated infections and multidrug resistant Gram-negative organisms.
Dr. Sopirala has mentored numerous fellows, residents and medical students throughout her career. Her work with the trainees has resulted in multiple peer reviewed publications. She is recognized as a leader in the field by national organizations and serves on the editorial boards for several reputed journals.
Education & Training
Professional Associations & Affiliations
- Society of Healthcare Epidemiology Long Term Care Interest Group
- Society for Healthcare Epidemiology of America
- Infectious Diseases Society of America
- American College of Physicians
Honors & Awards
- Honorable mention for partnership in prevention - SHEA-APIC Partnership in Prevention Award 2010, Fifth Decennial International Conference on Healthcare-Associated Infections
- Fellow 2012, American College of Physicians
- IMPACT award 2015, University of Cincinnati Medical Center
- Fellow 2016, Infectious Diseases Society of America
Books & Publications
Lung Abscesses and Pleural Abscesses in Infectious Diseases Third Edition
Sopirala MM, Mangino, JE (2009), United Kingdom, Elsevier
Tuberculosis in Treatment Strategies for Common Medical Problems Second Edition
Sopirala MM, Mangino, JE. (2009), United Kingdom, Elsevier
- Lung Abscesses and Pleural Abscesses in Infectious Diseases Third Edition
Infection control link nurse program: an interdisciplinary approach in targeting health care-acquired infection.
Sopirala MM, Yahle-Dunbar L, Smyer J, Wellington L, Dickman J, Zikri N, Martin J, Kulich P, Taylor D, Mekhjian H, Nash M, Mansfield J, Pancholi P, Howard M, Chase L, Brown S, Kipp K, Lefeld K, Myers A, Pan X, Mangino JE American journal of infection control 2014 Apr 42 4 353-9
Impact of a change in surveillance definition on performance assessment of a catheter-associated urinary tract infection prevention program at a tertiary care medical center.
Sopirala MM, Syed A, Jandarov R, Lewis M American journal of infection control 2018 Mar
Build upon basics: An intervention utilizing safety huddles to achieve near-zero incidence of catheter associated urinary tract infection at a department of Veterans Affairs long-term care facility.
Fiveash JM, Smith ML, Moore AK, Jandarov R, Sopirala MM, American journal of infection control 2021 Mar
Predisposition of COVID-19 patients to secondary infections: set in stone or subject to change?
Sopirala MM, Current opinion in infectious diseases 2021 May
Effect of automated ultraviolet C-emitting device on decontamination of hospital rooms with and without real-time observation of terminal room disinfection.
Penno K, Jandarov RA, Sopirala MM American journal of infection control 2017 Nov 45 11 1208-1213
An assessment of H1N1 influenza-associated acute respiratory distress syndrome severity after adjustment for treatment characteristics.
Riscili BP, Anderson TB, Prescott HC, Exline MC, Sopirala MM, Phillips GS, Ali NA PloS one 2011 Mar 6 3 e18166
Synergy testing by Etest, microdilution checkerboard, and time-kill methods for pan-drug-resistant Acinetobacter baumannii.
Sopirala MM, Mangino JE, Gebreyes WA, Biller B, Bannerman T, Balada-Llasat JM, Pancholi P Antimicrobial agents and chemotherapy 2010 Nov 54 11 4678-83
Preventing Catheter Related Blood Stream Infections Through a Multidisciplinary Team Effort
Exline MC, Sopirala MM Infectious Disease Special Edition 2012
Out of Sight-Out of Mind: Impact of Cascade Reporting on Antimicrobial Usage.
Liao S, Rhodes J, Jandarov R, DeVore Z, Sopirala MM, Open forum infectious diseases 2020 Feb 7 2 ofaa002
Does CDC's Ventilator Associated Event Definition Unintentionally Contradict its Antimicrobial Stewardship Initiative?
Sopirala MM Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2017 Jun
Prevention of Catheter-related Bloodstream Infections. An Overview of Current Approaches in Diagnosis, Management, and Prevention
Exline MC, Sopirala MM Infectious Disease Special Edition 2017 Spring
Prevention of Catheter-related Bloodstream Infections: An Overview of Current Approaches in Diagnosis, Management, and Prevention
Exline MC, Sopirala MM Infectious Disease Special Edition 2015 Fall
Effect of fever on hospital presentation, diagnosis, and treatment in patients with H1N1/09 influenza.
Sopirala MM, Haas DM, Ali NA, Mangino JE, Pan X, Turner AN Journal of hospital medicine 2013 Jan 8 1 20-4
Carbapenem-hydrolyzing gram-negative bacteria: current options for treatment and review of drugs in development.
Abandeh FI, Drew ME, Sopirala MM Recent patents on anti-infective drug discovery 2012 Apr 7 1 19-27
Beyond the bundle--journey of a tertiary care medical intensive care unit to zero central line-associated bloodstream infections.
Exline MC, Ali NA, Zikri N, Mangino JE, Torrence K, Vermillion B, St Clair J, Lustberg ME, Pancholi P, Sopirala MM Critical care (London, England) 2013 Mar 17 2 R41
Multidrug-resistant Acinetobacter baumannii pneumonia in lung transplant recipients.
Sopirala MM, Pope-Harman A, Nunley DR, Moffatt-Bruce S, Ross P, Martin SI The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2008 Jul 27 7 804-7
Acute leprosy in Ohio during treatment of HIV-AIDS.
Sopirala MM, Wininger DA, Ayers LW The New England journal of medicine 2011 Oct 365 16 1549-51
Assessment beyond central line bundle: audits for line necessity in infected central lines in a surgical intensive care unit.
Rotz S, Sopirala MM American journal of infection control 2012 Feb 40 1 88-9
Sustained reduction of central line-associated bloodstream infections in an intensive care unit using a top-down and bottom-up approach.
Sopirala MM, Smyer J, Fawley L, Mangino JE, Lustberg ME, Lu J, Chucta S, Crouser ED American journal of infection control 2013 Feb 41 2 183-4
- Infection control link nurse program: an interdisciplinary approach in targeting health care-acquired infection.
- Process improvement
- Multidrug resistant Gram-negative organisms
- Healthcare acquired infections