- Child Neurology Society
- The Epilepsy Study Consortium (TESC)
Mayank Verma, M.D., Ph.D.
- Pediatric Neurology
- Pediatric Epilepsy
- Neurogenetic Disorders
Biography
Mayank Verma, M.D., Ph.D., is an Assistant Professor in the Department of Pediatrics at UT Southwestern Medical Center. He specializes in pediatric epilepsies, neurogenetic disorders, and pediatric neuromuscular disorders.
After earning his medical degree and a doctorate in integrative biology and physiology at the University of Minnesota Medical School, Dr. Verma completed an internship in pediatrics at Children’s Medical Center Dallas. He completed his residency in child neurology at UT Southwestern, and gained advanced training through a research fellowship in gene therapy as part of his child neurology basic neuroscience pathway under Berge Minassian, M.D. Dr. Verma joined the UT Southwestern faculty in 2025.
His lab studies progressive myoclonic epilepsy and neuronal glycogen storage disorders; rare neurological disease that have no treatment; and the high burden of disease. As both a physician and a scientist, he works to translate discoveries from animal models into improved natural history and biomarker studies, with the goal of developing gene therapy clinical trials.
Dr. Verma sees patients in the neuromuscular clinic and the epilepsy clinic.
He presents regularly on genetic testing and gene therapy programs for rare neurological diseases. Dr. Verma has published and co-authored many articles, reviews, and book chapters.
Personal Note
When he’s not at work, Dr. Verma enjoys gardening and taking walks with his family.
Education & Training
- Medical School - , Medicine
Professional Associations & Affiliations
Honors & Awards
- Dean’s Scholar in Clinical Research 2026, UT Southwestern
- Award of Excellence 2025, Children’s Health Pediatric Neurology Clinic Nurses
- Resident Excellence in Care 2025, Children’s Health Neurosciences Floor Nurses
- First Place in Basic Science 2024, Dr. Susan Iannaccone Research Day
Books & Publications
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Publications
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Generation of Friedreich’s ataxia induced pluripotent stem cells carrying the FXN c.165 + 5G>C splicing mutation
Yameogo P, Gerhart BJ, Sentmanat MF, Neilson A, Cui X, Verma M, Lynch DR, Napierala JS, Napierala M Stem Cell Research 2026 Jun 93 -
Lafora disease gene therapy: EPM2A but not EPM2B overexpression results in Lafora body formation
Alao EO, Sheibani M, Wu J, Marriam U, Evans D, Kasiri S, Verma M, Nitschke S, Nitschke F, Gray SJ, Mitra S, Minassian BA Neurotherapeutics 2026 Mar 23 -
Neurofilament Light Chain as a Biomarker of Disease Progression in Lafora Disease
Muccioli L, Ganceviciute B, Becker F, Minardi R, Tappatà M, Bachhuber F, Alkhatib M, Cirak S, Weishaupt J, Verma M, Tumani H, Wagner J, Messahel S, Nitschke F, Minassian BA, Bisulli F, Brenner D Neurology: Genetics 2025 Dec 11 e200319 -
Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies
Fogel BL, Klopstock T, Lynch DR, Maltecca F, Verma M, Minassian BA, Platt FM, Gonçalves DF, Puccio H, Roos A, Synofzik M Annals of Neurology 2025 Sep 98 448-470 -
Focused ultrasound widely broadens AAV-delivered Cas9 distribution and activity
Gumusgoz E, Kasiri S, Youssef I, Verma M, Chopra R, Villarreal Acha D, Wu J, Marriam U, Alao E, Chen X, Guisso DR, Gray SJ, Shah BR, Minassian BA Gene Therapy 2025 May 32 237-245 -
Glycogen synthase GYS1 overactivation contributes to glycogen insolubility and malto-oligoglucan-associated neurodegenerative disease
Nitschke S, Montalbano AP, Whiting ME, Smith BH, Mukherjee-Roy N, Marchioni CR, Sullivan MA, Zhao X, Wang P, Mount H, Verma M, Minassian BA, Nitschke F EMBO Journal 2025 Mar 44 1379-1413 -
Protocol for the three-dimensional analysis of rodent skeletal muscle
Karthikeyan S, Asakura Y, Verma M, Asakura A STAR Protocols 2025 Mar 6 -
Myofiber-type-dependent ‘boulder’ or ‘multitudinous pebble’ formations across distinct amylopectinoses
Mitra S, Chen B, Shelton JM, Nitschke S, Wu J, Covington L, Dear M, Lynn T, Verma M, Nitschke F, Fuseya Y, Iwai K, Evers BM, Minassian BA Acta Neuropathologica 2024 Jun 147 -
Three-dimensional imaging studies in mice identify cellular dynamics of skeletal muscle regeneration
Collins BC, Shapiro JB, Scheib MM, Musci RV, Verma M, Kardon G Developmental cell 2024 Jun 59 1457-1474.e5 -
CSTB gene replacement improves neuroinflammation, neurodegeneration and ataxia in murine type 1 progressive myoclonus epilepsy
Gumusgoz E, Kasiri S, Verma M, Wu J, Villarreal Acha D, Marriam U, Fyffe-Maricich S, Lin A, Chen X, Gray SJ, Minassian BA Gene Therapy 2024 May 31 234-241 -
Unverricht-Lundborg disease
Verma M, Minassian BA, Andrade DM 2023 Jun 375-381 -
Tissue Clearing and Confocal Microscopic Imaging for Skeletal Muscle
Karthikeyan S, Asakura Y, Verma M, Asakura A 2023 453-462 -
Three-Dimensional Imaging Analysis for Skeletal Muscle
Karthikeyan S, Kim K, Asakura Y, Verma M, Asakura A 2023 463-477 -
VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy
Bosco J, Zhou Z, Gabriëls S, Verma M, Liu N, Miller BK, Gu S, Lundberg DM, Huang Y, Brown E, Josiah S, Meiyappan M, Traylor MJ, Chen N, Asakura A, De Jonge N, Blanchetot C, de Haard H, Duffy HS, Keefe D Molecular Therapy Methods and Clinical Development 2021 Jun 21 369-381 -
Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice
Bosnakovski D, Shams AS, Yuan C, da Silva MT, Ener ET, Baumann CW, Lindsay AJ, Verma M, Asakura A, Lowe DA, Kyba M Journal of Clinical Investigation 2020 May 130 2465-2477 -
Inhibition of microRNA-92a increases blood vessels and satellite cells in skeletal muscle but does not improve duchenne muscular dystrophy–related phenotype in mdx mice
Verma M, Asakura Y, Asakura A Muscle and Nerve 2019 May 59 594-602 -
Isometric resistance training increases strength and alters histopathology of dystrophin-deficient mouse skeletal muscle
Lindsay A, Larson AA, Verma M, Ervasti JM, Lowe DA Journal of Applied Physiology 2019 Feb 126 363-375 -
Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy
Verma M, Shimizu-Motohashi Y, Asakura Y, Ennen JP, Bosco J, Zhou Z, Fong GH, Josiah S, Keefe D, Asakura A PLoS genetics 2019 15 -
Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling
Verma M, Asakura Y, Murakonda BS, Pengo T, Latroche C, Chazaud B, McLoon LK, Asakura A Cell Stem Cell 2018 Oct 23 530-543.e9 -
CD301b/MGL2+ mononuclear phagocytes orchestrate autoimmune cardiac valve inflammation and fibrosis
Meier LA, Auger JL, Engelson BJ, Cowan HM, Breed ER, Gonzalez-Torres MI, Boyer JD, Verma M, Marath A, Binstadt BA Circulation 2018 137 2478-2493 -
Extraocular Muscle Repair and Regeneration
Verma M, Fitzpatrick KR, McLoon LK Current Ophthalmology Reports 2017 Sep 5 207-215 -
Skeletal muscle tissue clearing for LacZ and fluorescent reporters, and immunofluorescence staining
Verma M, Murkonda BS, Asakura Y, Asakura A Methods in Molecular Biology 2016 1460 129-140 -
Acute failure of action potential conduction in mdx muscle reveals new mechanism of contraction-induced force loss
Call JA, Warren GL, Verma M, Lowe DA Journal of Physiology 2013 Aug 591 3765-3776 -
Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5
Shi H, Verma M, Zhang L, Dong C, Flavell RA, Bennett AM Journal of Clinical Investigation 2013 May 123 2064-2077 -
Vascular-targeted therapies for Duchenne muscular dystrophy
Ennen JP, Verma M, Asakura A Skeletal Muscle 2013 Apr 3 -
Increased angiogenesis and improved left ventricular function after transplantation of myoblasts lacking the MyoD gene into infarcted myocardium
Nakamura Y, Asakura Y, Piras BA, Hirai H, Tastad CT, Verma M, Christ AJ, Zhang J, Yamazaki T, Yoshiyama M, Asakura A PloS one 2012 Jul 7 -
MyoD gene suppression by Oct4 is required for reprogramming in myoblasts to produce induced pluripotent stem cells
Watanabe S, Hirai H, Asakura Y, Tastad C, Verma M, Keller C, Dutton JR, Asakura A STEM CELLS 2011 Mar 29 505-516 -
Efficient single muscle fiber isolation from alcohol-fixed adult muscle following β-galactosidase staining for satellite cell detection
Verma M, Asakura A Journal of Histochemistry and Cytochemistry 2011 Jan 59 60-67 -
MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3
Hirai H, Verma M, Watanabe S, Tastad C, Asakura Y, Asakura A Journal of Cell Biology 2010 Oct 191 347-365 -
Flt-1 haploinsufficiency ameliorates muscular dystrophy phenotype by developmentally increased vasculature in mdx mice
Verma M, Asakura Y, Hirai H, Watanabe S, Tastad C, Fong GH, Ema M, Call JA, Lowe DA, Asakura A Human molecular genetics 2010 Aug 19 4145-4159 -
Post-mitotic role of nucleostemin as a promoter of skeletal muscle cell differentiation
Hirai H, Romanova L, Kellner S, Verma M, Rayner S, Asakura A, Kikyo N Biochemical and Biophysical Research Communications 2010 Jan 391 299-304 -
Increased survival of muscle stem cells lacking the MyoD gene after transplantation into regenerating skeletal muscle
Asakura A, Hirai H, Kablar B, Morita S, Ishibashi J, Piras BA, Christ AJ, Verma M, Vineretsky KA, Rudnicki MA Proceedings of the National Academy of Sciences of the United States of America 2007 Oct 104 16552-16557
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Generation of Friedreich’s ataxia induced pluripotent stem cells carrying the FXN c.165 + 5G>C splicing mutation
Research
- Neurogenetic disorders
- Antisense oligonucleotide (ASO) therapy for Lafora disease
- Natural history for progressive myoclonic epilepsy type 1
- MRI biomarkers for neuronal glycogen storage disorder
Clinical Focus
- Pediatric Epilepsy
- Neurogenetic Disorders
- Pediatric Neuromuscular Disorders
Children's Medical Center of Dallas
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