Meghana Sathe, M.D.

Pediatrics - Gastroenterology
Liver Disease

Biography

Dr. Meghana Sathe is a graduate of Wellesley College and the University of Miami Miller School of Medicine. She completed her internship and residency in Pediatrics and her fellowship in Pediatric Gastroenterology and Nutrition at the University of Texas Southwestern and Children's Medical Center Dallas. Dr. Sathe's clinical interests are general gastroenterology, hepatology and nutrition. She has a special interest in cystic fibrosis and is the co-medical director of the Claude Prestidge Cystic Fibrosis Foundation Clinic at Children's Medical Center Dallas. She also serves on the Medical Advisory Board of The Alagille Syndrome Alliance.

In addition to clinical care, Dr. Sathe is the Associate Fellowship Director for Division of Pediatric Gastroenterology and Nutrition. In this capacity, she is actively involved in the education of medical students, residents and fellows through lectures, conferences and curriculum development.

Dr. Sathe has been included in D Magazine's Best Doctors list, and was named a Super Doctor by Texas Monthly.

Education & Training

Medical School - University of Miami School of Medicine (1999-2003)
Internship - UT Southwestern/Children's Medical Center (2003-2004), Pediatrics
Residency - UT Southwestern/Children's Medical Center (2004-2006), Pediatrics
Fellowship - UT Southwestern/Children's Medical Center (2006-2009), Pediatric Gastroenterology

Professional Associations & Affiliations

Dallas County Medical Society/Texas Medical Society (2012)
Pediatric Society of Greater Dallas (2012)
American Board of Pediatrics, Gastroenterology (2009)
American Board of Pediatrics (2006)
North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (2006)
Texas Medical Board (2005)

Honors & Awards

D Magazine Best Doctor 2023-2025
D Magazine Best Pediatric Specialist, (2013-2017, 2020-2022)
Texas Super Doctor, Texas Monthly Magazine 2017-2017
Top Doctors in Dallas 2017, D Magazine
Texas Rising Stars 2016, Texas Monthly Magazine
Teaching and Tomorrow Program, 2nd World Congress, Paris, France 2004, NASPGHAN
Magna Cum Laude, Phi Beta Kappa, Sigma Chi, Wellesley College 1999

Books & Publications

Books
- Congenital enzyme and transport defects in Sondheimer J, Hurtado C, eds. The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition.
  Sathe M. (2011), New York: Castle Connolly.
- Liver Disease in Allen J, Panitch H, Rubenstein R, eds. Cystic Fibrosis: Lung Biology in Health and Disease. Vol 242.
  Sathe M, Feranchak AP. (2010), New York: Informa Healthcare USA.
- Pediatric Cystic Fibrosis and Fat-Soluble Vitamins in Watson RS, ed. Diet and Exercise in Cystic Fibrosis. 1st ed.
  Sathe M, Feranchak AP. (2015), Elsevier Inc.
- Cystic Fibrosis Associated Liver Disease in Suchy F, Sokol R, Balistreri W, eds. Liver Disease in Children. 4th ed.
  Sathe M, Feranchak AP. (2014), Cambridge University Press.
Publications
- Corrigendum to “Results of a clinical trial of ANG003, a non-porcine pancreatic enzyme replacement therapy, in people with cystic fibrosis”(Journal of Cystic Fibrosis, (2025), 24, 6, (1043-1050), (S1569199325015292), 10.1016/j.jcf.2025.07.008)
  Sathe M, Freedman SD, Putman MS, Gallotto R, Clarkin M, Gallotto D, Pierzynowska K, Borowitz D Journal of Cystic Fibrosis 2026 Jan 25 185
- Characterization of Pancreatic Cystosis Phenotype in People With Cystic Fibrosis
  Daves G, Polachek A, Troendle DM, Sathe M Pancreas 2026 55 e323-e324
- Results of a clinical trial of ANG003, a non-porcine pancreatic enzyme replacement therapy, in people with cystic fibrosis
  Sathe M, Freedman SD, Putman MS, Gallotto R, Clarkin M, Gallotto D, Pierzynowska K, Borowitz D Journal of Cystic Fibrosis 2025 Nov 24 1043-1050
- Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
  Wood W, Pottorff A, Lazar L, Sathe M Journal of Visualized Experiments 2025 Aug 2025-August
- Improving Modulator Management and Side Effect Screening: A CF Learning Network Innovation Lab
  Author Collaboration Ft, Lonabaugh KP, Saulitis A, Boettinger E, Brighton D, Akers M, Barber AT, Gifford AH, Kubiak SE, McNamara SC, Ries O, Schulke DF, List R, Shen S, Horton BJ, Albon D, Ong T, Linnemann RW, Dangel G, Gordon R, Joseph M, Lemieux A, Sawicki G, Tran V, Lawrence M, McMahon L, Uluer A, Baxter B, Hazen M, House M, McKinnon M, Pendley S, Robinson W, Amin R, Hjelm M, Miller J, Moore S, Mullen L, Proffitt J, Roach J, Selker N, Siracusa C, Traver K, Wacker M, Garbarz J, Newman E, Pancham K, Poonawala-Manjee S, Renner K, Sathe M, Sharma P Pediatric pulmonology 2025 Jul 60
- Cystic Fibrosis Learning Network Telehealth Innovation Lab During the COVID-19 Pandemic: Impact on Access to Care, Outcomes, and a New CF Care Model
  Albon D, Ong T, Horton B, Brighton D, Shen S, List R, Antos N, Asfour F, Balasa E, Beachler D, Daines C, Froh D, Kier C, Nasr S, Sathe M, Sawicki G, Schechter M, Solomon G, Powers M Pediatric pulmonology 2025 May 60
- Validation of dietary whey protein substrate challenge absorption test as an indicator of proteolysis
  Pierzynowska K, Pierzynowski S, Zaworski K, Gallotto R, Sathe M, Freedman SD, Borowitz D PloS one 2025 May 20
- Estimating minimal clinically important difference (MCID) for gastrointestinal symptoms in cystic fibrosis
  Lee MJ, Sathe M, Moshiree B, Vu PT, Heltshe SL, Schwarzenberg SJ, Freedman SD, Freeman AJ Journal of Cystic Fibrosis 2024 Sep 23 991-999
- Remaining barriers to normalcy in cystic fibrosis: Considerations in GI, liver, and nutrition
  Sathe M, Stein A Pediatric pulmonology 2024 Sep 59 S5
- Cystic fibrosis hepatobiliary involvement: an update on imaging in diagnosis and monitoring
  Wood W, Tinich T, Lazar L, Schooler GR, Sathe M Pediatric radiology 2024 Aug 54 1416-1427
- Association of in-line digestive enzyme cartridge with enteral feeds on improvement in anthropometrics among pediatric patients with cystic fibrosis
  Shrivastava S, Shaw K, Lee M, Reitich P, Hunter S, Klosterman M, Sathe M Nutrition in Clinical Practice 2024 Aug 39 903-910
- Guiding caregivers of infants with CF in understanding differences in pediatric growth charts
  Bass R, Ren C, Kordunova D, Schindler T, Salzedo S, Omori M, Leonard A, Scandurro N, Yavelow M, Borowitz D, Powers KE, Maguiness K, Sathe M Journal of Cystic Fibrosis 2024 Jul 23 771-773
- Interventions to improve system-level coproduction in the Cystic Fibrosis Learning Network
  Author Collaboration TC, Gamel B, Albon D, Bandla S, Davison DW, Flath J, Sabadosa KA, Seid M, Silva L, Ong T, Powers M, Amin R, Britto M, Saulitis A, Bailey J, Moore E, Daines C, Drake G, Lucero A, Miller D, Sharpe A, Sawicki G, Barnico K, Gordon R, Murphy C, Lemieux A, Dangel G, O’Leary L, Uluer A, McMahon L, Lawrence M, Murray M, Goetz D, Woerner D, Whelan M, Violanti K, Sathe M, Sharma P, Attel S, Liberto T, Varghese P, Linnemann R, Hernández Cargal A, Clute K, Ries O, Tirakitsoontorn P, Gage S, Kominek B, Lawrence K, Poulin D, Sou M BMJ Open Quality 2024 Jul 13
- Remote endpoints for clinical trials in cystic fibrosis: Report from the U.S. CF foundation remote endpoints task force
  Hoppe JE, Sjoberg J, Hong G, Poch K, Zemanick ET, Thee S, Edmondson C, Patel D, Sathe M, Borowitz D, Putman MS, Lechtzin N, Riekert KA, Basile M, Goss CH, Jarosz ME, Rosenfeld M Journal of Cystic Fibrosis 2024 Jul 23 725-733
- Cystic fibrosis screening, evaluation, and management of hepatobiliary disease consensus recommendations
  Sellers ZM, Assis DN, Paranjape SM, Sathe M, Bodewes F, Bowen M, Cipolli M, Debray D, Green N, Hughan KS, Hunt WR, Leey J, Ling SC, Morelli G, Peckham D, Pettit RS, Philbrick A, Stoll J, Vavrina K, Allen S, Goodwin T, Hempstead SE, Narkewicz MR Hepatology 2024 May 79 1220-1238
- Cross-Cutting mHealth Behavior Change Techniques to Support Treatment Adherence and Self-Management of Complex Medical Conditions: Systematic Review
  Eaton CK, McWilliams E, Yablon D, Kesim I, Ge R, Mirus K, Sconiers T, Donkoh A, Lawrence M, George C, Morrison ML, Muther E, Oates GR, Sathe M, Sawicki GS, Snell C, Riekert K JMIR mHealth and uHealth 2024 12
- Intrahepatic Cholangiolitis in Cystic Fibrosis (ICCF): An Under-Appreciated Cause of Persistent Cholestasis in Infancy
  Bernieh A, Bove K, Garcia V, Tiao G, Lazar L, Sathe M, Sanchez J, Gonzalez R, Gonzalez-Gomez I Pediatric and Developmental Pathology 2024 Jan 27 13-22
- Evaluating Feasibility, Acceptability, and Effectiveness of a Digital Behavioral Nutrition Intervention in Cystic Fibrosis Care
  Opipari-Arrigan L, Kouril M, Connor J, Ford C, McWilliams E, Green A, Siracusa C, Milla C, Muther E, Nasr SZ, Sathe M, Sawicki GS, Schechter MS, Snell C, Stark LJ Clinical Practice in Pediatric Psychology 2024
- Female Excellence and Leadership in Pediatrics Subspecialties (FLEXPeds): Creating a Network for Women Across Academic Pediatrics
  Author Collaboration F, Dammann CE, Kieran K, Fromme HB, Espinosa C, Tarantino CA, Trent M, Lightdale JR, Bline K, Alcorta C, Asaki SY, Balasubramanian S, Barral R, Bauer A, Bernardo E, Boomer L, Bowman J, Bryant T, Capal J, Chumpitazi C, D'Souza J, Emrick B, Flannery A, Giel D, Gilbert T, Gillispie-Taylor M, Granberg C, Haq H, Hawryluk E, Herce H, Hernandez-Trujillo V, Janow G, Jones-Betancourt M, Kim J, Kimball-Eayrs C, Kriel H, Landrigan-Ossar M, Lau M, Machut K, Malone LD, Mann M, Mastrandrea L, Montgomery A, Nalk-Mathuria B, Niazi T, Prather H, Rahmandar M, Reardon J, Rigsby C, Riley A, Sathe M Journal of Pediatrics 2023 Dec 263
- Evaluation of the Use of Appetite Stimulants in Pediatric Patients with Cystic Fibrosis
  Kennedy K, Lee MJ, Sathe M, Ueng CS, Sharma P Journal of pediatric gastroenterology and nutrition 2023 Oct 77 565-572
- Food for thought: The revolution stirring within nutritional care priorities in cystic fibrosis
  Sathe MN, King SJ Journal of Cystic Fibrosis 2023 Sep 22 785-787
- Standardizing and optimizing nutrition evaluation frequency of enterally fed patients in an ambulatory pediatric gastroenterology practice: A single-center study
  Ngai D, Kotamraju S, Do P, Luffy R, Winser-Bean C, Rockwell J, Hollaway L, Wright V, Barlow S, Sathe M Nutrition in Clinical Practice 2023 Aug 38 863-870
- Patient Attitudes Regarding Health Care Clinician Communication in Adolescents with Cystic Fibrosis
  Woolley JC, Edmondson SN, Sathe MN, Rodriguez Francis JK Journal of pediatric gastroenterology and nutrition 2023 Aug 77 E23-E28
- Validation of an omega-3 substrate challenge absorption test as an indicator of global fat lipolysis
  Freedman SD, Zaworski K, Pierzynowska K, Pierzynowski S, Gallotto R, Sathe M, Borowitz DS PloS one 2023 May 18
- The use of DXA for early detection of pediatric cystic fibrosis-related bone disease
  Chadwick C, Arcinas R, Ham M, Huang R, Hunter S, Mehta M, Sharma P, Varghese PA, Williams K, Troendle DM, Sathe M Pediatric pulmonology 2023 Apr 58 1136-1144
- Need to study simplification of gastrointestinal medication regimen in cystic fibrosis in the era of highly effective modulators
  Sathe M, Moshiree B, Aliaj E, Lee MJ, Hudson J, Gifford A, Attel S, Gamel B, Freedman SD, Schwarzenberg SJ, Freeman AJ Pediatric pulmonology 2023 Mar 58 811-818
- Multicenter prospective study showing a high gastrointestinal symptom burden in cystic fibrosis
  Author Collaboration GS, Moshiree B, Freeman AJ, Vu PT, Khan U, Ufret-Vincenty C, Heltshe SL, Goss CH, Schwarzenberg SJ, Freedman SD, Borowitz D, Sathe M Journal of Cystic Fibrosis 2023 Mar 22 266-274
- Association between stool consistency and clinical variables among infants with cystic fibrosis: Findings from the BONUS study
  Author Collaboration BS, Freeman AJ, Huang R, Heltshe SL, Gelfond D, Leung DH, Ramsey BR, Borowitz D, Sathe M Journal of Cystic Fibrosis 2022 Sep 21 830-836
- The mammalian SKIV2L RNA exosome is essential for early B cell development
  Yang K, Han J, Gill JG, Park JY, Sathe MN, Gattineni J, Wright T, Wysocki C, de la Morena MT, Yan N Science Immunology 2022 May 7
- A step back in time: The basics of CF care still matter!
  Sathe M, Paul GR, Faro A Pediatric pulmonology 2022 Mar 57 597-599
- Understanding Cystic Fibrosis Comorbidities and Their Impact on Nutritional Management
  Patel D, Shan A, Mathews S, Sathe M Nutrients 2022 Mar 14
- Cytoplasmic RNA quality control failure engages mTORC1-mediated autoinflammatory disease
  Yang K, Han J, Asada M, Gill JG, Park JY, Sathe MN, Gattineni J, Wright T, Wysocki CA, Teresa de la Morena M, Garza LA, Yan N Journal of Clinical Investigation 2022 Jan 132
- Variations in Nutrition Practices in Cystic Fibrosis: A Survey of the DIGEST Program
  Shaikhkhalil AK, Freeman AJ, Sathe M Nutrition in Clinical Practice 2021 Dec 36 1247-1251
- Hypoplasia of Extrahepatic Biliary Tree and Intrahepatic Cholangiolopathy in Cystic Fibrosis Imperfectly Mimic Biliary Atresia in 4 Infants With Cystic Fibrosis and Kasai Portoenterostomy
  Bove KE, Bernieh A, Picarsic J, Cox JP, Yang E, Mantor PC, Thaker A, Lazar L, Sathe M, Megison S American Journal of Surgical Pathology 2021 Nov 45 1499-1508
- Year in review 2020: Nutrition and gastrointestinal disease in cystic fibrosis
  Sathe M, Sharma PB, Savant AP Pediatric pulmonology 2021 Oct 56 3120-3125
- Year in Review 2020: Multisystemic impact of cystic fibrosis
  Sharma PB, Sathe M, Savant AP Pediatric pulmonology 2021 Oct 56 3110-3119
- Gastrointestinal Factors Associated With Hospitalization in Infants With Cystic Fibrosis: Results From the Baby Observational and Nutrition Study
  Sathe M, Huang R, Heltshe S, Eng A, Borenstein E, Miller SI, Hoffman L, Gelfond D, Leung DH, Borowitz D, Ramsey B, Jay Freeman A Journal of pediatric gastroenterology and nutrition 2021 Sep 73 395-402
- Utilization of electronic patient-reported outcome measures in cystic fibrosis research: Application to the GALAXY study
  Sathe M, Moshiree B, Vu PT, Khan U, Heltshe SL, Romasco M, Freedman SD, Schwarzenberg SJ, Goss CH, Freeman AJ Journal of Cystic Fibrosis 2021 Jul 20 605-611
- Designing the GALAXY study: Partnering with the cystic fibrosis community to optimize assessment of gastrointestinal symptoms
  Freeman AJ, Sathe M, Aliaj E, Borowitz D, Fogarty B, Goss CH, Freedman S, Heltshe SL, Khan U, Riva D, Roman C, Romasco M, Schwarzenberg SJ, Ufret-Vincenty CA, Moshiree B Journal of Cystic Fibrosis 2021 Jul 20 598-604
- Use of proton pump inhibitors is associated with lower hemoglobin levels in people with cystic fibrosis
  Gifford AH, Sanville JL, Sathe M, Heltshe SL, Goss CH Pediatric pulmonology 2021 Jul 56 2048-2056
- Cystic Fibrosis Liver Disease in Children
  Lazar L, Sathe M, Feranchak D 2021 Jan 437-454
- Gender-affirming hormone therapy in cystic fibrosis – A case of new Pseudomonas infection
  Shaffer L, Bozkanat K, Lau M, Sharma P, Sathe M, Lopez X, Jain R Respiratory Medicine Case Reports 2021 Jan 32
- Evaluation of the effectiveness of in-line immobilized lipase cartridge in enterally fed patients with cystic fibrosis
  Sathe MN, Patel D, Stone A, First E Journal of pediatric gastroenterology and nutrition 2021 Jan 72 18-23
- From pancreatitis to Puestow: The winding path of cystic fibrosis
  Chadwick CB, Megison S, Troendle DM, Sathe M Journal of Pediatric Surgery Case Reports 2020 Feb 53
- Is meconium ileus associated with worse outcomes in cystic fibrosis?
  Sathe M, Houwen R Journal of Cystic Fibrosis 2019 Nov 18 746
- Acute Recurrent and Chronic Pancreatitis as Initial Manifestations of Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator-Related Disorders
  Baldwin C, Zerofsky M, Sathe M, Troendle DM, Perito ER Pancreas 2019 Aug 48 888-893
- Meconium ileus in Cystic Fibrosis
  Sathe M, Houwen R Journal of Cystic Fibrosis 2017 Nov 16 S32-S39
- Gastrointestinal, Pancreatic, and Hepatobiliary Manifestations of Cystic Fibrosis
  Sathe MN, Freeman AJ Pediatric clinics of North America 2016 Aug 63 679-698
- Liver disease
  Sathe MN, Feranchak AP 2016 Apr 285-307
- Pediatric Cystic Fibrosis and Fat-Soluble Vitamins
  Beckett K, Shaw K, Sathe M 2015 125-130
- An 18-month-old boy with severe dermatitis, edema, muscle wasting
  Mittal VS, Sathe M, Troendle D, Cox M Pediatric annals 2011 Aug 40 393-396
- Regulation of purinergic signaling in biliary epithelial cells by exocytosis of SLC17A9-dependent ATP-enriched vesicles
  Sathe MN, Woo K, Kresge C, Bugde A, Luby-Phelps K, Lewis MA, Feranchak AP Journal of Biological Chemistry 2011 Jul 286 25363-25376
- Cystic fibrosis liver disease
  Sathe M, Feranchak AP 2011 Jan 419-434
- Adenosine triphosphate release and purinergic (P2) receptor-mediated secretion in small and large mouse cholangiocytes
  Woo K, Sathe M, Kresge C, Esser V, Ueno Y, Venter J, Glaser SS, Alpini G, Feranchak AP Hepatology 2010 Nov 52 1819-1828
- Update in pediatrics: Focus on fat-soluble vitamins
  Sathe MN, Patel AS Nutrition in Clinical Practice 2010 Aug 25 340-346
- Initiation of purinergic signaling by exocytosis of ATP-containing vesicles in liver epithelium
  Feranchak AP, Lewis MA, Kresge C, Sathe M, Bugde A, Luby-Phelps K, Antich PP, Fitz JG Journal of Biological Chemistry 2010 Mar 285 8138-8147
- Identification and functional characterization of the intermediate- conductance Ca²⁺-activated K⁺ channel (IK-1) in biliary epithelium
  Dutta AK, Khimji AK, Sathe M, Kresge C, Parameswara V, Esser V, Rockey DC, Feranchak AP American Journal of Physiology - Gastrointestinal and Liver Physiology 2009 Nov 297 G1009-G1018

Research

Nutrition
Cystic fibrosis associated liver disease
Cystic fibrosis and nutrition

Clinical Focus

Liver Disease

Links

New Patient Appointment

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Meghana Sathe, M.D.

Biography

Education & Training

Professional Associations & Affiliations

Honors & Awards

Books & Publications

Research

Clinical Focus

Links

Children's Medical Center of Dallas

Meghana Sathe, M.D.

Biography

Education & Training

Professional Associations & Affiliations

Honors & Awards

Books & Publications

Research

Clinical Focus

Links

Children's Medical Center of Dallas

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