- Infectious Disease Society of America
- American Academy of Pediatrics
Natasha Hanners, M.D.
- Pediatrics - Infectious Disease
Biography
Dr. Hanners is an early career physician-scientist. As a pediatric resident, chief resident, pediatric infectious disease fellow, and now as a faculty member, Dr. Hanners developed and pursued her interest in encephalitis. She is interested in the pathophysiology and immune response to viral central nervous system (CNS) infections. Dr. Hanners’ research involves the investigation of interferon-stimulated genes (ISGs) for antiviral effects on neurotropic viruses including Venezuelan equine encephalitis (VEEV), yellow fever (YFV), West Nile (WNV) and Zika (ZIKV) viruses. She has also pursued her interest in CNS infections by investigating the effects of Zika virus infection on neural progenitor cells.
Dr. Hanners has focused her research career on elucidating the molecular pathogenesis of Flavivirus CNS infections, as well as the innate immune response to such infections. She will also continue her clinical work in Pediatric Infectious Diseases, and have a particular interest in patients with CNS infections.
Education & Training
- Residency - UT Southwestern/Children's Medical Center (2009-2012), Pediatrics
- Chief Resident - UT Southwestern/Children's Medical Center (2012-2013), Pediatrics
- Fellowship - UT Southwestern/Children's Medical Center (2013-2016), Pediatric Infectious Diseases
- Medical School - UT Southwestern Medical School (2005-2009)
Professional Associations & Affiliations
Honors & Awards
- D Magazine Best Doctor 2025
- Excellence in Research Award 2016, UT Southwestern and Children's Health Department of Pediatrics
- W.W. Caruth Scholar Fellow Research Award 2015-2017
- Fellow of the Year Award, Pediatric Residency Program Award 2013-2014
- Provider of the Month Award 2010, Family-Centered Care Committee, Parkland Hospital's Neonatal Intensive Care Unit
- Southwestern Medical Foundation Competitive Scholar Award 2005-2009
Books & Publications
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Publications
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STT3A-mediated mega protein complex assembly during dengue and Zika virus infection
Liu T, Hanners NW, Tao H, Szabo C, Xu D, Lin W, Schoggins JW, Yan N, Wu J iScience 2025 Jun 28 -
Challenges and advances in the medical treatment of granulomatous amebic encephalitis
Spottiswoode N, Haston JC, Hanners NW, Gruenberg K, Kim A, DeRisi JL, Wilson MR Therapeutic Advances in Infectious Disease 2024 Jan 11 -
Gastrointestinal Manifestations Are Associated with Severe COVID-19 in Children
Akkoyun EB, Ashraf B, Hanners N, Kahn J, Most Z Healthcare (Switzerland) 2024 Jan 12 -
LY6E is a pan-coronavirus restriction factor in the respiratory tract
Mar KB, Wells AI, Caballero Van Dyke MC, Lopez AH, Eitson JL, Fan W, Hanners NW, Evers BM, Shelton JM, Schoggins JW Nature microbiology 2023 Aug 8 1587-1599 -
Shiftless inhibits flavivirus replication in vitro and is neuroprotective in a mouse model of Zika virus pathogenesis
Hanners NW, Mar KB, Boys IN, Eitson JL, De La Cruz-Rivera PC, Richardson RB, Fan W, Wight-Carter M, Schoggins JW Proceedings of the National Academy of Sciences of the United States of America 2021 Dec 118 -
SARS-CoV-2 infection associated with hepatitis in an infant with X-linked severe combined immunodeficiency
van Oers NS, Hanners NW, Sue P, Aquino V, Li QZ, Schoggins JW, Wysocki CA Clinical Immunology 2021 Mar 224 -
LY6E impairs coronavirus fusion and confers immune control of viral disease
Pfaender S, Mar KB, Michailidis E, Kratzel A, Boys IN, V’kovski P, Fan W, Kelly JN, Hirt D, Ebert N, Stalder H, Kleine-Weber H, Hoffmann M, Hoffmann HH, Saeed M, Dijkman R, Steinmann E, Wight-Carter M, McDougal MB, Hanners NW, Pöhlmann S, Gallagher T, Todt D, Zimmer G, Rice CM, Schoggins JW, Thiel V Nature microbiology 2020 Nov 5 1330-1339 -
Evolving Peri-Anal Mass in 2-Year-Old
Yang A, Hanners NW, Dakil S, Evans AS, Rakheja D, Lee M Pediatric Infectious Disease Journal 2020 Sep 39 873-875 -
Case 1: Apnea and hypotonia in a i-month-old infant
Hoge M, Thomas JM, Hanners NW, Castro DP, Ali N Pediatrics in Review 2019 Oct 20 e592-e593 -
A NIK–SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB
Liu Z, Mar KB, Hanners NW, Perelman SS, Kanchwala M, Xing C, Schoggins JW, Alto NM Nature 2019 Apr 568 249-253 -
Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects
Hanners NW, Eitson JL, Usui N, Richardson RB, Wexler EM, Konopka G, Schoggins JW Cell Reports 2016 Jun 15 2315-2322 -
A persistently fussy, febrile infant
Cantey JB, Hanners N, Mittal V Clinical Pediatrics 2012 Jan 51 93-95
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STT3A-mediated mega protein complex assembly during dengue and Zika virus infection
Research
- Virus-host interactions
- Type I Interferon responses
- Neurovirology
- Flavivirus infections, including Zika virus neurotropism
Children's Medical Center of Dallas
1935 Medical District DriveDallas, Texas 75235 214-730-5437 Directions to Children's Medical Center of Dallas at Children's Medical Center of Dallas, Dallas