Nicolas Madsen, M.D.

Chief, Division of Pediatric Cardiology

Pogue Family Distinguished Chair in Pediatric Cardiology

Pediatrics - Cardiology
Pediatric acute care cardiology
Congenital Heart Disease

Biography

Nicolas L. Madsen, M.D., M.P.H., is a Professor in the Department of Pediatrics at UT Southwestern Medical Center. He specializes in pediatric cardiology and congenital heart disease, with a particular focus on hospital-based management.

Dr. Madsen earned his medical degree at the University of Washington, where he also completed a residency in pediatrics and received advanced training through a pediatric cardiology fellowship. Additionally, he holds a master’s degree in public health from the University of Washington.

Certified by the American Board of Pediatrics in pediatric cardiology, Dr. Madsen joined the UT Southwestern faculty in 2021. Previously, he served as Medical Director of the Heart Institute and the Acute Care Cardiology Unit at Cincinnati Children’s Hospital Medical Center.

Dr. Madsen is a nationally recognized clinician and researcher in acute care cardiology and congenital heart disease. He is co-founder and Executive Director of the Pediatric Acute Care Cardiology Collaborative (PAC3), an organization that enables medical professionals across North America to collaborate to improve care of and outcomes in children who are hospitalized with heart conditions.

He serves as Chief of the Division of Pediatric Cardiology as well as Co-Director of the Heart Center at Children’s Health. A Fellow of the American Academy of Pediatrics, he is a member of numerous professional societies, including the American College of Cardiology, the Pediatric Congenital Heart Association, and the American Heart Association.

Dr. Madsen is an Adjunct Professor at Aarhus University in the Department of Clinical Epidemiology. In addition, he has a dual appointment at UT Southwestern as Associate Professor in the Department of Data Science and Population Health.

He has delivered scores of presentations, contributed to books such as Common Cardiac

Issues in Pediatrics, and published a number of academic articles related to his areas of expertise.

“I can think of no greater profession than pediatric cardiology,” Dr. Madsen says. “The opportunities for positive and lasting impact are evident everywhere and across the lifespan. It is a privilege to provide the most advanced clinical care for the benefit of our patients, from the newborn period and throughout their potentially complex journey to adulthood.”

Personal Note

Dr. Madsen enjoys spending time with his family and discovering new trails in the great outdoors. In addition to English, he speaks Danish.

Education & Training

Medical School - University of Washington School of Medicine (2001-2005)
Residency - University of Washington/Seattle Children's Hospital (2005-2008), Pediatrics
Other Post Graduate Training - University of Washington School of Public Health (2008-2011)
Fellowship - University of Washington/Seattle Children's Hospital (2009-2012), Pediatric Cardiology

Professional Associations & Affiliations

American Academy of Pediatrics
American College of Cardiology
American Heart Association
Dallas County Medical Society
Pediatric Cardiac Critical Care Consortium
Pediatric Congenital Heart Association
Pediatric Heart Network

Honors & Awards

Cincinnati Top Doctors 2020
Top Abstract (CVDY) 2019, American Heart Association Scientific Sessions
Cincinnati Top Doctors 2019
Patient Education Advocacy Award 2018, Home Care for Heart Health
Clinical Care Achievement Award 2017, Cincinnati Children’s Hospital
Heart Hero Award 2017, Pediatric Congenital Heart Association
Make a Difference Award 2016, Cincinnati Children’s Hospital
Early Bird Career (Specialty Focus) Best Poster 2015, American Heart Association Scientific Sessions
Advocacy Day Training Scholarship Award 2015, AAP Section on Cardiology and Cardiac Surgery
Third Place Abstract 2014, 24th Annual Symposium on the Adult with Congenital Heart Disease
Outstanding Fellow Teaching Award 2012, Seattle Children’s Hospital
Young Investigator Award Finalist 2011, AAP Section on Cardiology and Cardiac Surgery
Education Travel Grant Recipient 2011, AAP Section on Cardiology and Cardiac Surgery
Corkey Travel Award 2011, Seattle Children’s Hospital, University of Washington School of Medicine
Fellow’s Teaching Award 2011, Seattle Children’s Hospital
Cardiology Outstanding Investigator Award 2010, Children’s Hospital of Philadelphia
Young Investigator’s Travel Award 2010, Pediatric Academic Society Annual Meeting
Loan Repayment Program Recipient 2009-2011, National Institute of Health
Outstanding Clinical Research Award 2010-2012, Seattle Children’s Fellow’s College Research Day
Travel Grant 2009, Department of Clinical Epidemiology, University of Aarhus, Denmark

Books & Publications

Books
- Chapter 19, Congenital heart lesions, Pulmonary Stenosis in Common Cardiac Issues in Pediatrics
  Anderson H, Madsen NL, Batlivala S, Kyle WB, Putschoegl A, Johnson J. (2018), Itasca, IL, American Academy of Pediatrics
- Chapter 19, Congenital heart lesions, Tetralogy of Fallot in Common Cardiac Issues in Pediatrics
  Madsen NL, Batlivala S, Kyle WB, Putschoegl A, Johnson J (2018), Itasca, IL, American Academy of Pediatrics
- Chapter 19, Congenital heart lesions, Atrial Septal Defects in Common Cardiac Issues in Pediatrics
  Thompson AJ, Madsen NL, Batlivala S, Kyle WB, Putschoegl A, Johnson J (2018), Itasca, IL, American Academy of Pediatrics
- Pediatric Critical Care Medicine: Respiratory, Cardiovascular and Central Nervous Systems in Long-Term Outcomes in Congenital Heart Disease
  Heydarian H, Madsen NL, Marino BS (2014), London, UK, Springer
Publications
- Comparison of Economic Self-Sufficiency and Educational Attainment in Adults With Congenital Heart Disease Versus Siblings Without Heart Disease and to General Population.
  Madsen NL, Marino BS, Woo JG, Olsen M, The American journal of cardiology 2020 11 135 135-142
- Effectiveness and Safety of Statin Therapy in Children: A Real-World Clinical Practice Experience.
  Kavey RW, Manlhiot C, Runeckles K, Collins T, Gidding SS, Demczko M, Clauss S, Harahsheh AS, Mietus-Syder M, Khoury M, Madsen N, McCrindle BW, CJC open 2020 Nov 2 6 473-482
- Health literacy and caregiver understanding in the CHD population.
  Rodts ME, Unaka NI, Statile CJ, Madsen NL, Cardiology in the young 2020 Oct 30 10 1439-1444
- Intensive Care Unit and Acute Care Unit Length of Stay After Congenital Heart Surgery.
  Hart SA, Tanel RE, Kipps AK, Hoerst AK, Graupe MA, Cassidy SC, Hlavacek AM, Clabby ML, Bush LB, Zhang W, Banerjee MM, Pasquali SK, Gaies M, Madsen N, The Annals of thoracic surgery 2020 10 110 4 1396-1403
- Time series evaluation of improvement interventions to reduce alarm notifications in a paediatric hospital.
  Pater CM, Sosa TK, Boyer J, Cable R, Egan M, Knilans TK, Schondelmeyer AC, Schuler CL, Madsen NL, BMJ quality & safety 2020 09 29 9 717-726
- Center Variation in Chest Tube Duration and Length of Stay After Congenital Heart Surgery.
  Bates KE, Madsen NL, Khadr L, Gao Z, Crawford K, Gaies M, Graupe M, Hanke SP, Hlavacek AM, Morell E, Pasquali SK, Russell JL, Schachtner SK, Tanel RE, Ware AL, Kipps AK, The Annals of thoracic surgery 2020 07 110 1 221-227
- The Pediatric Heart Network Residual Lesion Score Study: Design and objectives.
  Nathan M, Trachtenberg FL, Van Rompay MI, Gaynor W, Kanter K, Ohye R, Bacha EA, Tweddell J, Schwartz SM, Minich LL, Mery CM, Colan SD, Levine J, Lambert LM, Newburger JW, The Journal of thoracic and cardiovascular surgery 2020 07 160 1 218-223.e1
- Congenital Heart Disease and Risk of Central Nervous System Infections: A Nationwide Cohort Study.
  Bagge CN, Smit J, Madsen NL, Olsen M, Pediatric cardiology 2020 Jun 41 5 869-876
- Reduction in myocardial strain is evident in adolescents and young adults with obesity and type 2 diabetes.
  Haley JE, Zhiqian G, Philip KR, Nicolas ML, Thomas KR, Lawrence DM, Elaine UM, Pediatric diabetes 2020 03 21 2 243-250
- Reaching the paediatric chest pain audience outside of ambulatory clinic using internet-based education.
  Powell AW, Ritzenthaler Z, Powell KW, Camper R, Madsen NL, BMJ paediatrics open 2020 4 1 e000778
- Development of a clinician-parent home care education intervention.
  Lane B, Hanke SP, Giambra B, Madsen NL, Staveski SL, Cardiology in the young 2019 Oct 29 10 1230-1235
- Ischemic Stroke in Adults With Congenital Heart Disease: A Population-Based Cohort Study.
  Pedersen MGB, Olsen MS, Schmidt M, Johnsen SP, Learn C, Laursen HB, Madsen NL, Journal of the American Heart Association 2019 08 8 15 e011870
- Variation in care practices across pediatric acute care cardiology units: Results of the Pediatric Acute Care Cardiology Collaborative (PAC³ ) hospital survey.
  Hoerst A, Bakar A, Cassidy SC, Clabby M, Grippo ED, Graupe M, Harahsheh AS, Hlavacek AM, Hart SA, Kipps AK, Madsen NL, O'Neil DD, Patel SS, Strohacker CM, Tanel RE, Congenital heart disease 2019 May 14 3 419-426
- Cardiac Networks United: an integrated paediatric and congenital cardiovascular research and improvement network.
  Gaies M, Anderson J, Kipps A, Lorts A, Madsen N, Marino B, Costello JM, Brown D, Jacobs JP, Kasnic D, Lihn S, Lannon C, Margolis P, Pearson GD, Kaltman J, Charpie JR, Redington AN, Pasquali SK, Cardiology in the young 2019 Feb 29 2 111-118
- Screening and Management of High Blood Pressure in Children and Adolescents.
  Khoury M, Madsen N, JAMA pediatrics 2018 11 172 11 1087-1088
- Collective quality improvement in the paediatric cardiology acute care unit: establishment of the Pediatric Acute Care Cardiology Collaborative (PAC3).
  Kipps AK, Cassidy SC, Strohacker CM, Graupe M, Bates KE, McLellan MC, Harahsheh AS, Hanke SP, Tanel RE, Schachtner SK, Gaies M, Madsen N, Cardiology in the young 2018 Aug 28 8 1019-1023
- Longitudinal Health Care Cost in Hypoplastic Left Heart Syndrome Palliation.
  Hansen JE, Madsen NL, Bishop L, Morales DLS, Anderson JB, Pediatric cardiology 2018 Aug 39 6 1210-1215
- Incidence and Mortality of Adults With Pulmonary Hypertension and Congenital Heart Disease.
  Schwartz SS, Madsen N, Laursen HB, Hirsch R, Olsen MS, The American journal of cardiology 2018 06 121 12 1610-1616
- Risk of Dementia in Adults With Congenital Heart Disease: Population-Based Cohort Study.
  Bagge CN, Henderson VW, Laursen HB, Adelborg K, Olsen M, Madsen NL, Circulation 2018 05 137 18 1912-1920
- Optimizing patient care and outcomes through the congenital heart center of the 21st century.
  Anderson JB, Chowdhury D, Connor JA, Daniels CJ, Fleishman CE, Gaies M, Jacobs J, Kugler J, Madsen N, Beekman RH, Lihn S, Stewart-Huey K, Vincent R, Campbell R, Congenital heart disease 2018 Mar 13 2 167-180
- Utilizing a transfer of care bundle to reduce unplanned readmissions to the cardiac intensive care unit.
  Storey J, Byrnes JW, Anderson J, Brown J, Clarke-Myers K, Kimball M, Meyer C, Mustin L, Schoenling G, Madsen N, BMJ quality & safety 2018 01 27 1 66-72
- Arterial Thickness and Stiffness Are Independently Associated with Left Ventricular Strain.
  Mehta S, Khoury PR, Madsen NL, Dolan LM, Kimball TR, Urbina EM, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2018 01 31 1 99-104
- Myocardial Infarction in Adults With Congenital Heart Disease.
  Olsen M, Marino B, Kaltman J, Laursen H, Jakobsen L, Mahle W, Pearson G, Madsen N, The American journal of cardiology 2017 Dec 120 12 2272-2277
- Cardiac surgery in patients with congenital heart disease is associated with acute kidney injury and the risk of chronic kidney disease.
  Madsen NL, Goldstein SL, Frøslev T, Christiansen CF, Olsen M, Kidney international 2017 09 92 3 751-756
- Congenital heart disease and the prevalence of underweight and obesity from age 1 to 15 years: data on a nationwide sample of children.
  Schwartz S, Olsen M, Woo JG, Madsen N, BMJ paediatrics open 2017 1 1 e000127
- Congenital Heart Defects and Risk of Epilepsy: A Population-Based Cohort Study.
  Leisner MZ, Madsen NL, Ostergaard JR, Woo JG, Marino BS, Olsen MS, Circulation 2016 11 134 21 1689-1691
- Congenital Heart Disease With and Without Cyanotic Potential and the Long-term Risk of Diabetes Mellitus: A Population-Based Follow-up Study.
  Madsen NL, Marino BS, Woo JG, Thomsen RW, Videbœk J, Laursen HB, Olsen M, Journal of the American Heart Association 2016 07 5 7
- A 14-Year-Old Boy with Unusual Presentation of Respiratory Distress.
  Powell AW, Hanke S, Tweddell JS, Madsen N, Case reports in pediatrics 2016 2016 7313942
- Melody Valve Bartonella henselae Endocarditis in an Afebrile Teen: A Case Report.
  Sosa T, Goldstein B, Cnota J, Bryant R, Frenck R, Washam M, Madsen N, Pediatrics 2016 Jan 137 1
- Usefulness of combined history, physical examination, electrocardiogram, and limited echocardiogram in screening adolescent athletes for risk for sudden cardiac death.
  Anderson JB, Grenier M, Edwards NM, Madsen NL, Czosek RJ, Spar DS, Barnes A, Pratt J, King E, Knilans TK, The American journal of cardiology 2014 Dec 114 11 1763-7
- The preparticipation physical evaluation: an analysis of clinical practice.
  Madsen NL, Drezner JA, Salerno JC, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine 2014 Mar 24 2 142-9
- Prepregnancy body mass index and congenital heart defects among offspring: a population-based study.
  Madsen NL, Schwartz SM, Lewin MB, Mueller BA, Congenital heart disease 2013 Mar-Apr 8 2 131-41
- Sudden cardiac death screening in adolescent athletes: an evaluation of compliance with national guidelines.
  Madsen NL, Drezner JA, Salerno JC, British journal of sports medicine 2013 Feb 47 3 172-7

Research

Pediatric acute care cardiology
Long-term outcomes in congenital heart disease
Quality improvement science

Clinical Focus

Pediatric acute care cardiology
Congenital Heart Disease
Post-operative surgical care