- Fellowship - Harvard Medical School/Massachusetts General Hospital (1990-1994), Endocrinology & Metabolism
- Residency - Harvard Medical School/Massachusetts General Hospital (1988-1990), Internal Medicine
- Medical School - UT Southwestern Medical School (1984-1988)
Perry Bickel, M.D.
- Daniel W. Foster, M.D., Distinguished Chair in Internal Medicine
- Internal Medicine - Endocrinology
Biography
Perry E. Bickel, M.D., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He serves as Chief of the Division of Endocrinology and holds the Daniel W. Foster, M.D., Distinguished Chair in Internal Medicine. He specializes in endocrinology.
Dr. Bickel earned his medical degree at UT Southwestern Medical School. He completed both his residency in internal medicine and fellowship in endocrinology and metabolism at Massachusetts General Hospital. He also performed a research fellowship at Harvard Medical School and served as a visiting scientist at the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts.
Certified by the American Board of Internal Medicine in endocrinology, diabetes, and metabolism, Dr. Bickel joined the UT Southwestern faculty in 2012.
Among his other roles, Dr. Bickel is the Associate Program Director of UT Southwestern’s Endocrine and Metabolism Training Grant. His research lab investigates how cells store and use fat and the underlying mechanisms that could be targeted to develop safe and effective treatments for diabetes and obesity.
Dr. Bickel is a member of the American Diabetes Association, the Dallas County Medical Society, the Endocrine Society, and the Obesity Society.
He is a D Magazine Best Doctor.
Education & Training
Honors & Awards
- D Magazine Best Doctor 2020-2022
Books & Publications
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Publications
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Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance.
Gallardo-Montejano VI, Yang C, Hahner L, McAfee JL, Johnson JA, Holland WL, Fernandez-Valdivia R, Bickel PE, Nature communications 2021 06 12 1 3320 -
Deciphering the Role of Lipid Droplets in Cardiovascular Disease: A Report From the 2017 National Heart, Lung, and Blood Institute Workshop.
Goldberg IJ, Reue K, Abumrad NA, Bickel PE, Cohen S, Fisher EA, Galis ZS, Granneman JG, Lewandowski ED, Murphy R, Olive M, Schaffer JE, Schwartz-Longacre L, Shulman GI, Walther TC, Chen J Circulation 2018 Jul 138 3 305-315 -
Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1a/SIRT1-dependent transcriptional regulation of mitochondrial function.
Gallardo-Montejano VI, Saxena G, Kusminski CM, Yang C, McAfee JL, Hahner L, Hoch K, Dubinsky W, Narkar VA, Bickel PE Nature communications 2016 7 12723 -
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores.
Bickel PE, Tansey JT, Welte MA Biochimica et biophysica acta 2009 Jun 1791 6 419-40 -
Lipid droplets in lipogenesis and lipolysis.
Ducharme NA, Bickel PE Endocrinology 2008 Mar 149 3 942-9 -
OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization.
Wolins NE, Quaynor BK, Skinner JR, Tzekov A, Croce MA, Gropler MC, Varma V, Yao-Borengasser A, Rasouli N, Kern PA, Finck BN, Bickel PE Diabetes 2006 Dec 55 12 3418-28 -
A proposed model of fat packaging by exchangeable lipid droplet proteins.
Wolins NE, Brasaemle DL, Bickel PE FEBS letters 2006 Oct 580 23 5484-91 -
Insulin promotes shedding of syndecan ectodomains from 3T3-L1 adipocytes: a proposed mechanism for stabilization of extracellular lipoprotein lipase.
Reizes O, Goldberger O, Smith AC, Xu Z, Bernfield M, Bickel PE Biochemistry 2006 May 45 18 5703-11 -
OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis.
Wolins NE, Quaynor BK, Skinner JR, Tzekov A, Park C, Choi K, Bickel PE Journal of lipid research 2006 Feb 47 2 450-60 -
S3-12, Adipophilin, and TIP47 package lipid in adipocytes.
Wolins NE, Quaynor BK, Skinner JR, Schoenfish MJ, Tzekov A, Bickel PE The Journal of biological chemistry 2005 May 280 19 19146-55 -
Adipocyte protein S3-12 coats nascent lipid droplets.
Wolins NE, Skinner JR, Schoenfish MJ, Tzekov A, Bensch KG, Bickel PE The Journal of biological chemistry 2003 Sep 278 39 37713-21 -
CAP defines a second signalling pathway required for insulin-stimulated glucose transport.
Baumann CA, Ribon V, Kanzaki M, Thurmond DC, Mora S, Shigematsu S, Bickel PE, Pessin JE, Saltiel AR Nature 2000 Sep 407 6801 202-7 -
A detergent-insoluble membrane compartment contains A beta in vivo.
Lee SJ, Liyanage U, Bickel PE, Xia W, Lansbury PT, Kosik KS Nature medicine 1998 Jun 4 6 730-4 -
Cloning of cell-specific secreted and surface proteins by subtractive antibody screening.
Scherer PE, Bickel PE, Kotler M, Lodish HF Nature biotechnology 1998 Jun 16 6 581-6 -
Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins.
Bickel PE, Scherer PE, Schnitzer JE, Oh P, Lisanti MP, Lodish HF The Journal of biological chemistry 1997 May 272 21 13793-802 -
Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cells.
Bickel PE, Freeman MW The Journal of clinical investigation 1992 Oct 90 4 1450-7
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Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance.