- Residency - UT Southwestern Medical School (2009-2011), Internal Medicine
- Fellowship - UT Southwestern Medical Center (2011-2014), Endocrinology & Metabolism
- Medical School - Albert Ludwigs Universitat (1995-2003)
Peter Gerhard Zechner, M.D., Ph.D.
- Internal Medicine - Endocrinology
Dr. Zechner is originally from Germany and completed his medical school and research doctorate at the University of Freiburg, combined with a research fellowship at Yale University. After a medical internship at the University of Würzburg, he completed a postdoctoral fellowship in the laboratory of Dr. Daniel P. Kelly at Washington University in St. Louis and the Sanford-Burnham Medical Research Institute at Lake Nona. Subsequently, he moved to UT Southwestern to complete his clinical training in internal medicine and endocrinology as a member of the Physician-Scientist Training Program. He joined the laboratory of Drs. David J. Mangelsdorf and Steven A. Kliewer to study intestinal hormones and their actions on energy and phosphate metabolism. In his spare time, Dr. Zechner enjoys biking in the Texas heat, playing and watching soccer, and taking advantage of the great cultural opportunities that Dallas offers, especially the symphony.
- Texas Medical Association (2009), Member
- American Medical Association (2010), Member
- Endocrine Society (2011), Member
- American Diabetes Association (2011), Member
- American Society for Bone and Mineral Research (2013), Member
- Best Presentation by an Endocrinology Fellow 2013, UT Southwestern, Department of Internal Medicine, Division of Endocrinology
- Research Productivity and Accomplishment Award 2014, UT Southwestern, Department of Internal Medicine, Division of Endocrinology
- Scholarship for Participation in the Biomedical Sciences Exchange Program (BMEP) 2000-2001, German Academic Exchange Service
- Research Scholarship 2006-2008, German Research Foundation
Discrepancy between GLUT4 translocation and glucose uptake after ischemia.
Zaha V, Nitschke R, Göbel H, Fischer-Rasokat U, Zechner C, Doenst T Molecular and cellular biochemistry 2005 Oct 278 1-2 129-37
Hyperglycemia during cardiopulmonary bypass is an independent risk factor for mortality in patients undergoing cardiac surgery.
Doenst T, Wijeysundera D, Karkouti K, Zechner C, Maganti M, Rao V, Borger MA The Journal of thoracic and cardiovascular surgery 2005 Oct 130 4 1144
A role for the transcriptional coactivator PGC-1alpha in muscle refueling.
Wende AR, Schaeffer PJ, Parker GJ, Zechner C, Han DH, Chen MM, Hancock CR, Lehman JJ, Huss JM, McClain DA, Holloszy JO, Kelly DP The Journal of biological chemistry 2007 Dec 282 50 36642-51
Uncoupling protein downregulation in doxorubicin-induced heart failure improves mitochondrial coupling but increases reactive oxygen species generation.
Bugger H, Guzman C, Zechner C, Palmeri M, Russell KS, Russell RR Cancer chemotherapy and pharmacology 2011 Jun 67 6 1381-8
Functional protein expression of multiple sodium channel alpha- and beta-subunit isoforms in neonatal cardiomyocytes.
Kaufmann SG, Westenbroek RE, Zechner C, Maass AH, Bischoff S, Muck J, Wischmeyer E, Scheuer T, Maier SK Journal of molecular and cellular cardiology 2010 Jan 48 1 261-9
Structural insights into gene repression by the orphan nuclear receptor SHP.
Zhi X, Zhou XE, He Y, Zechner C, Suino-Powell KM, Kliewer SA, Melcher K, Mangelsdorf DJ, Xu HE Proceedings of the National Academy of Sciences of the United States of America 2014 Jan 111 2 839-44
Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity.
Zechner C, Lai L, Zechner JF, Geng T, Yan Z, Rumsey JW, Collia D, Chen Z, Wozniak DF, Leone TC, Kelly DP Cell metabolism 2010 Dec 12 6 633-42
Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart.
Lai L, Leone TC, Zechner C, Schaeffer PJ, Kelly SM, Flanagan DP, Medeiros DM, Kovacs A, Kelly DP Genes & development 2008 Jul 22 14 1948-61
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury.
Russell RR, Li J, Coven DL, Pypaert M, Zechner C, Palmeri M, Giordano FJ, Mu J, Birnbaum MJ, Young LH The Journal of clinical investigation 2004 Aug 114 4 495-503
The role of calcium in the regulation of glucose uptake in isolated working rat heart.
Zechner C, Beyersdorf F, Doenst T Molecular and cellular biochemistry 2002 Mar 232 1-2 75-80
- Discrepancy between GLUT4 translocation and glucose uptake after ischemia.
- Phosphate Metabolism
- Gut Hormones
- Energy Metabolism