- Fellowship - Ohio State University Hospitals (1997-1999), Nephrology
- Residency - Aultman Hospital - NEOUCOM (1995-1997), Internal Medicine
- Internship - Aultman Hospital - NEOUCOM (1994-1995), Internal Medicine
- Medical School - Delhi University/Maulana Azad Medical College (1980-1986)

Ramesh Saxena, M.D., Ph.D.
- Internal Medicine - Nephrology
- Chronic Kidney Disease
- Glomerulonephritis
New Patient Appointment Accepting Virtual Visits or 214-645-8300
Biography
Ramesh Saxena, M.D., Ph.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center. He specializes in the treatment of lupus nephritis, glomerulonephritis, and peritoneal dialysis.
Originally from India, Dr. Saxena earned his medical degree at Maulana Azad Medical College in New Delhi, and his doctoral degree in autoimmune glomerulonephritis at Lund University in Sweden. He completed his residency in internal medicine at Northeastern Ohio University College of Medicine in Canton, and received advanced training through a postdoctoral fellowship at Case Western Reserve University in Cleveland and a nephrology fellowship at The Ohio State University Hospitals in Columbus, Ohio.
Certified by the American Board of Internal Medicine in nephrology, he joined the UT Southwestern faculty in 1999.
Among other roles, Dr. Saxena is Medical Director of UT Southwestern’s Davita Irving Dialysis Center. He serves on the Clinician Educator Compensation Plan Committee and the Clinical Competency Committee for Renal Fellows at UT Southwestern, where he is also a Clinical Documentation Improvement Provider Champion in Nephrology. In addition, since 2009 he has provided patient care at the Denton County India Culture Association’s Annual Free Clinic.
He is a Fellow of the American Society of Nephrology and a member of the International Society of Peritoneal Dialysis and other professional organizations, and he serves on the editorial board of the Journal of Vascular Access.
Dr. Saxena has delivered scores of lectures, published numerous peer-reviewed articles, and contributed chapters to several books, including Andreoli & Carpenter’s Cecil Essentials of Medicine and Silva’s Diagnostic Renal Pathology.
In 2012 and 2015, he received UT Southwestern’s Excellence in Teaching Award in Nephrology.
Education & Training
Professional Associations & Affiliations
- American Society of Nephrology
- Dallas County Medical Society
- International Society of Nephrology
- International Society of Peritoneal Dialysis
- National Kidney Foundation
- Texas Medical Association
Honors & Awards
- D Magazine Best Doctor 2021
- Excellence in Teaching Award, (2012, 2015) UT Southwestern Medical Center
- Anna Greta Crafoord Prize for best PhD thesis at Lund University 1991, Crafoord Foundation
- Fellow 2015, American Society of Nephrology
Books & Publications
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Publications
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Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway.
Min SY, Fu Y, Hutcheson J, Wu T, Khobahy E, Zhu J, Vanarsa K, Du Y, Park MJ, Park HS, Saxena R, Kim HY, Mohan C Clinical immunology (Orlando, Fla.) 2012 Apr 143 1 59-72 -
Novel source of human hematopoietic stem cells from peritoneal dialysis effluents.
Shen J, Zheng J, Saxena R, Zhang C, Tang L Stem cell research 2015 Jul 15 2 299-304 -
Peritoneal Dialysis: Misperceptions and Reality.
Saxena R The American journal of the medical sciences 2014 May -
Quantitative planar array screen of 1000 proteins uncovers novel urinary protein biomarkers of lupus nephritis.
Vanarsa K, Soomro S, Zhang T, Strachan B, Pedroza C, Nidhi M, Cicalese P, Gidley C, Dasari S, Mohan S, Thai N, Truong VTT, Jordan N, Saxena R, Putterman C, Petri M, Mohan C, Annals of the rheumatic diseases 2020 Jul -
Specificity of kidney-bound antibodies in Goodpasture's syndrome.
Saxena R, Bygren P, Butkowski R, Wieslander J, Clinical and experimental immunology 1989 Oct 78 1 31-6 -
Circulating anti-entactin antibodies in patients with glomerulonephritis.
Saxena R, Bygren P, Cederholm B, Wieslander J, Kidney international 1991 May 39 5 996-1004 -
Circulating autoantibodies as serological markers in the differential diagnosis of pulmonary renal syndrome.
Saxena R, Bygren P, Arvastson B, Wieslander J, Journal of internal medicine 1995 Aug 238 2 143-52 -
The effect of erythropoietin on autologous stem cell-mediated bone regeneration.
Nair AM, Tsai YT, Shah KM, Shen J, Weng H, Zhou J, Sun X, Saxena R, Borrelli J, Tang L Biomaterials 2013 Oct 34 30 7364-71 -
IGFBP-2 as a novel biomarker for disease activity and renal pathology changes in lupus nephritis.
Ding H, Kharboutli M, Saxena R, Wu T Clinical and experimental immunology 2015 Nov -
Identification of Low-Abundance Urinary Biomarkers in Lupus Nephritis using Electrochemiluminescence Immunoassays.
Stanley S, Mok CC, Vanarsa K, Habazi D, Li J, Predoza C, Saxena R, Mohan C Arthritis & rheumatology (Hoboken, N.J.) 2019 Jan -
Urinary pro-thrombotic, anti-thrombotic, and fibrinolytic molecules as biomarkers of lupus nephritis.
Qin L, Stanley S, Ding H, Zhang T, Truong V, Celhar T, Fairhurst AM, Pedroza C, Petri M, Saxena R, Mohan C, Arthritis research & therapy 2019 Jul 21 1 176 -
Chemokine releasing particle implants for trapping circulating prostate cancer cells.
Huang Y, Hakamivala A, Li S, Nair A, Saxena R, Hsieh JT, Tang L, Scientific reports 2020 Mar 10 1 4433 -
A rapid assay for circulating anti-glomerular basement membrane antibodies in Goodpasture syndrome.
Saxena R, Isaksson B, Bygren P, Wieslander J, Journal of immunological methods 1989 Mar 118 1 73-8 -
Entactin: a possible auto-antigen in the pathogenesis of non-Goodpasture anti-GBM nephritis.
Saxena R, Bygren P, Butkowski R, Wieslander J, Kidney international 1990 Aug 38 2 263-72 -
Activation of Na/H exchanger in mesangial cells is associated with translocation of PKC isoforms.
Saxena R, Saksa BA, Fields AP, Ganz MB, The American journal of physiology 1993 Jul 265 1 Pt 2 F53-60 -
Significance of anti-entactin antibodies in patients with systemic lupus erythematosus and related disorders.
Saxena R, Sturfelt G, Nived O, Wieslander J, Annals of the rheumatic diseases 1994 Oct 53 10 659-65 -
Inhibition of ras p21 membrane localization and modulation of protein kinase C isozyme expression during regression of chemical carcinogen-induced murine skin tumors by lovastatin.
Khan SG, Saxena R, Bickers DR, Mukhtar H, Agarwal R, Molecular carcinogenesis 1995 Apr 12 4 205-12 -
PDGF and IL-1 induce and activate specific protein kinase C isoforms in mesangial cells.
Ganz MB, Saksa B, Saxena R, Hawkins K, Sedor JR, The American journal of physiology 1996 Jul 271 1 Pt 2 F108-13 -
Protein kinase C beta II isoform is up-regulated in human proliferative glomerulonephritis.
Ganz MB, Abu-Nader R, Saxena R, Grond J, Experimental nephrology 1997 May-Jun 5 3 225-32 -
Risk factors associated with peritoneal dialysis catheter survival: a 9-year single-center study in 315 patients.
Singh N, Davidson I, Minhajuddin A, Gieser S, Nurenberg M, Saxena R The journal of vascular access 2010 Oct-Dec 11 4 316-22 -
Lupus nephritis: current update.
Saxena R, Mahajan T, Mohan C Arthritis research & therapy 2011 13 5 240 -
Lupus Nephritis: A Retrospective Analysis of Clinical Presentation and Outcomes From a Single Center.
Singh S, Zhou XJ, Ahn C, Saxena R The American journal of the medical sciences 2011 Jun -
Metabolic disturbances associated with systemic lupus erythematosus.
Wu T, Xie C, Han J, Ye Y, Weiel J, Li Q, Blanco I, Ahn C, Olsen N, Putterman C, Saxena R, Mohan C PloS one 2012 7 6 e37210 -
Urine VCAM-1 as a marker of renal pathology activity index in lupus nephritis.
Singh S, Wu T, Xie C, Vanarsa K, Han J, Mahajan T, Oei HB, Ahn C, Zhou XJ, Putterman C, Saxena R, Mohan C Arthritis research & therapy 2012 Jul 14 4 R164 -
Urinary Angiostatin - a novel marker of renal pathology chronicity in lupus nephritis.
Wu T, Du Y, Han J, Singh S, Xie C, Guo Y, Zhou XJ, Ahn C, Saxena R, Mohan C Molecular & cellular proteomics : MCP 2013 Jan -
Resistin as a potential marker of renal disease in lupus nephritis.
Hutcheson J, Ye Y, Han J, Arriens C, Saxena R, Li QZ, Mohan C, Wu T Clinical and experimental immunology 2014 Oct -
Characteristics and Outcomes of Renal Transplant Recipients with Hemolytic Uremic Syndrome in the United States.
Tanriover B, Lakhia R, Shen YM, Sandikci B, Saxena R, MacConmara M, Soyombo AA, Rajora N, Hardy MA Transplantation direct 2015 Nov 1 10 -
Insulin-Like Growth Factor Binding Protein-4 as a Marker of Chronic Lupus Nephritis.
Wu T, Xie C, Han J, Ye Y, Singh S, Zhou J, Li Y, Ding H, Li QZ, Zhou X, Putterman C, Saxena R, Mohan C PloS one 2016 11 3 e0151491 -
Antibody array based proteomic screening of serum markers in systemic lupus erythematosus - a discovery study.
Wu T, Ding H, Han J, Arriens C, Wei C, Han W, Pedroza C, Jiang S, Anolik J, Petri M, Sanz I, Saxena R, Mohan C Journal of proteome research 2016 May -
Urine angiostatin and VCAM-1 surpass conventional metrics in predicting elevated renal pathology activity indices in lupus nephritis.
Soliman S, Mohamed FA, Ismail FM, Stanley S, Saxena R, Mohan C International journal of rheumatic diseases 2017 Oct -
Peritoneal Dialysis Is Feasible as a Bridge to Combined Liver-Kidney Transplant.
Jones RE, Liang Y, MacConmara M, Hwang C, Saxena R Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2018 Jan-Feb 38 1 63-65 -
A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis.
Rovin BH, Solomons N, Pendergraft WF, Dooley MA, Tumlin J, Romero-Diaz J, Lysenko L, Navarra SV, Huizinga RB, Kidney international 2019 01 95 1 219-231 -
Elevated oxidized lipids, anti-lipid autoantibodies and oxidized lipid immune complexes in active SLE.
Ye Y, Wu T, Zhang T, Han J, Habazi D, Saxena R, Mohan C, Clinical immunology (Orlando, Fla.) 2019 May 205 43-48 -
Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities.
Stanley S, Vanarsa K, Soliman S, Habazi D, Pedroza C, Gidley G, Zhang T, Mohan S, Der E, Suryawanshi H, Tuschl T, Buyon J, Putterman C, Mok CC, Petri M, Saxena R, Mohan C, Nature communications 2020 May 11 1 2197 -
Tissue engineering bone using autologous progenitor cells in the peritoneum.
Shen J, Nair A, Saxena R, Zhang CC, Borrelli J, Tang L PloS one 2014 9 3 e93514 -
Association of Urine sCD163 With Proliferative Lupus Nephritis, Fibrinoid Necrosis, Cellular Crescents and Intrarenal M2 Macrophages.
Zhang T, Li H, Vanarsa K, Gidley G, Mok CC, Petri M, Saxena R, Mohan C, Frontiers in immunology 2020 11 671 -
A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression.
Rovin BH, Lu L, Saxena R, Biochemical and biophysical research communications 1999 Jun 259 2 344-8 -
Prognostic significance of repeat biopsy in lupus nephritis: Histopathologic worsening and a short time between biopsies is associated with significantly increased risk for end stage renal disease and death.
Arriens C, Chen S, Karp DR, Saxena R, Sambandam K, Chakravarty E, James JA, Merrill JT Clinical immunology (Orlando, Fla.) 2016 Dec
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Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway.
Research
- Lupus Nephritis
- Glomerulonephritis
- Peritoneal Dialysis
Clinical Focus
- Chronic Kidney Disease
- Glomerulonephritis
- Kidney Disease (Nephrology)
- Lupus nephritis
- Peritoneal dialysis
Results: 1 Locations
University Hospital Kidney and Liver Transplant Clinic
at Professional Office Building 2 5939 Harry Hines Blvd., 7th Floor, Suite 700Dallas, Texas 75390 214-645-1919 Directions to University Hospital Kidney and Liver Transplant Clinic Parking Info for University Hospital Kidney and Liver Transplant Clinic
New Patient Appointment Accepting Virtual Visits or 214-645-8300 or 817-882-2400