Ravikanth Maddipati, M.D.

Internal Medicine - Digestive and Liver Diseases
Pancreatitis
Pancreatic Cysts

Biography

Ravikanth Maddipati, M.D., is an Assistant Professor in the Division of Digestive and Liver Diseases at UT Southwestern Medical Center. He specializes in pancreatic disorders and the management of patients at high risk for developing pancreatic cancer.

Dr. Maddipati holds a bachelor's degree in computer and electrical engineering from the University of Michigan, where he graduated magna cum laude. He remained there to obtained a master's degree in biomedical engineering. He earned his medical degree with honors from Boston University School of Medicine, and completed a residency in internal medicine at Massachusetts General Hospital, He then received advanced training in gastroenterology through a fellowship at the University of Pennsylvania.

Certified by the American Board of Internal Medicine, Dr. Maddipati joined the UT Southwestern faculty in 2019.

His research interests include pancreatic cancer, tumor metastasis, and pancreatitis.

He is a member of the American Association for Cancer Research, the American Association for the Study of Liver Diseases, the American Gastroenterological Association, the American Pancreatic Association, and the American Society for Gastrointestinal Endoscopy.

Books & Publications

Publications
- Ablative radiotherapy in oligometastatic pancreatic cancer to delay polyprogression, limit chemotherapy, and improve outcomes.
  Elamir AM, Karalis JD, Sanford NN, Polanco PM, Folkert MR, Porembka MR, Kazmi SA, Maddipati R, Zeh HJ, Timmerman RD, Zhang S, Ligorio M, Beg MS, Aguilera TA, International journal of radiation oncology, biology, physics 2022 Jul
- Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer.
  Huang H, Wang Z, Zhang Y, Pradhan RN, Ganguly D, Chandra R, Murimwa G, Wright S, Gu X, Maddipati R, Müller S, Turley SJ, Brekken RA, Cancer cell 2022 Apr
- MYC levels regulate metastatic heterogeneity in pancreatic adenocarcinoma.
  Maddipati R, Norgard RJ, Baslan T, Rathi KS, Zhang A, Saeid A, Higashihara T, Wu F, Kumar A, Annamalai V, Bhattacharya S, Raman P, Adkisson CA, Pitarresi JR, Wengyn MD, Yamazoe T, Li J, Balli D, LaRiviere MJ, Ngo TC, Folkert IW, Millstein ID, Bermeo J, Carpenter EL, McAuliffe JC, Oktay MH, Brekken RA, Lowe SW, Iacobuzio-Donahue CA, Notta F, Stanger BZ, Cancer discovery 2021 Sep
- Calcium signaling induces a partial EMT.
  Norgard RJ, Pitarresi JR, Maddipati R, Aiello-Couzo NM, Balli D, Li J, Yamazoe T, Wengyn MD, Millstein ID, Folkert IW, Rosario-Berrios DN, Kim IK, Bassett JB, Payne R, Berry CT, Feng X, Sun K, Cioffi M, Chakraborty P, Jolly MK, Gutkind JS, Lyden D, Freedman BD, Foskett JK, Rustgi AK, Stanger BZ, EMBO reports 2021 Jul e51872
- Cancer-Associated Fibroblasts: Versatile Players in the Tumor Microenvironment.
  Ganguly D, Chandra R, Karalis J, Teke M, Aguilera T, Maddipati R, Wachsmann MB, Ghersi D, Siravegna G, Zeh HJ, Brekken R, Ting DT, Ligorio M, Cancers 2020 Sep 12 9
- Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer.
  Reichert M, Bakir B, Moreira L, Pitarresi JR, Feldmann K, Simon L, Suzuki K, Maddipati R, Rhim AD, Schlitter AM, Kriegsmann M, Weichert W, Wirth M, Schuck K, Schneider G, Saur D, Reynolds AB, Klein-Szanto AJ, Pehlivanoglu B, Memis B, Adsay NV, Rustgi AK, Developmental cell 2018 06 45 6 696-711.e8
- EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration.
  Aiello NM, Maddipati R, Norgard RJ, Balli D, Li J, Yuan S, Yamazoe T, Black T, Sahmoud A, Furth EE, Bar-Sagi D, Stanger BZ, Developmental cell 2018 06 45 6 681-695.e4
- Pancreatic cancer survival analysis defines a signature that predicts outcome.
  Raman P, Maddipati R, Lim KH, Tozeren A, PloS one 2018 13 8 e0201751
- KLF4 Initiates Acinar Cell Reprogramming and Is Essential for the Early Stages of Pancreatic Carcinogenesis.
  Maddipati R, Katz JP, Cancer cell 2016 Mar 29 3 247-248
- Pancreatic Cancer Metastases Harbor Evidence of Polyclonality.
  Maddipati R, Stanger BZ, Cancer discovery 2015 Oct 5 10 1086-97
- Hippo signaling regulates differentiation and maintenance in the exocrine pancreas.
  Gao T, Zhou D, Yang C, Singh T, Penzo-Méndez A, Maddipati R, Tzatsos A, Bardeesy N, Avruch J, Stanger BZ, Gastroenterology 2013 Jun 144 7 1543-53, 1553.e1
- Robust cellular reprogramming occurs spontaneously during liver regeneration.
  Yanger K, Zong Y, Maggs LR, Shapira SN, Maddipati R, Aiello NM, Thung SN, Wells RG, Greenbaum LE, Stanger BZ, Genes & development 2013 Apr 27 7 719-24
- Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS).
  Bulua AC, Simon A, Maddipati R, Pelletier M, Park H, Kim KY, Sack MN, Kastner DL, Siegel RM, The Journal of experimental medicine 2011 Mar 208 3 519-33
- Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome.
  Simon A, Park H, Maddipati R, Lobito AA, Bulua AC, Jackson AJ, Chae JJ, Ettinger R, de Koning HD, Cruz AC, Kastner DL, Komarow H, Siegel RM, Proceedings of the National Academy of Sciences of the United States of America 2010 May 107 21 9801-6
- Peptide-conjugated quantum dots activate neuronal receptors and initiate downstream signaling of neurite growth.
  Vu TQ, Maddipati R, Blute TA, Nehilla BJ, Nusblat L, Desai TA, Nano letters 2005 Apr 5 4 603-7

Clinical Focus

Pancreatitis
Pancreatic Cysts
High Risk and Hereditary Gastrointestinal Malignancy Screening

New Patient Appointment or 214-645-0595

Ravikanth Maddipati, M.D.

Biography

Books & Publications

Clinical Focus

Pancreatic Cancer Prevention Program