- Research Fellowship - UT Southwestern Medical Center (2005-2008), Research
- Fellowship - UT Southwestern Medical Center (2004-2006), Nephrology
- Residency - McGaw Medical Center of Northwestern University (2002-2004), Internal Medicine
- Internship - Mount Sinai Hospital Medical Center (2001-2002), Internal Medicine
- Medical School - Pramukhswami Medical School, India (1994-2000)
Vishal Patel, M.D.
- Internal Medicine - Nephrology
- American Society of Nephrology
- Chief Fellow, UT Southwestern Medical Center-Nephrology fellowship 2006
- SSCI Young Investigator Travel award 2007
- UT Southwestern O’Brien Center-Pilot and Feasibility Grant 2009
- NIDDK-Career Development Award 2009
- Rising star in Nephrology - State of Texas 2012, Super Doctors
Advances in the pathogenesis and treatment of polycystic kidney disease.
Patel V, Chowdhury R, Igarashi P Current opinion in nephrology and hypertension 2009 Mar 18 2 99-106
Renal Dysgenesis (Chapter),
Fangming Lin, Vishal Patel, and Peter Igarashi Genetic Diseases of the Kidney 2009, Edited by Lifton, Somlo, Giebisch, and Seldin 2009
microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
Hajarnis S, Lakhia R, Yheskel M, Williams D, Sorourian M, Liu X, Aboudehen K, Zhang S, Kersjes K, Galasso R, Li J, Kaimal V, Lockton S, Davis S, Flaten A, Johnson JA, Holland WL, Kusminski CM, Scherer PE, Harris PC, Trudel M, Wallace DP, Igarashi P, Lee EC, Androsavich JR, Patel V Nature communications 2017 Feb 8 14395
Transcription Factor HNF-1ß Regulates MicroRNA-200 Expression Through a Long Noncoding RNA.
Hajarnis SS, Patel V, Aboudehen K, Attanasio M, Cobo-Stark P, Pontoglio M, Igarashi P The Journal of biological chemistry 2015 Aug
Loss of oriented cell division does not initiate cyst formation.
Nishio S, Tian X, Gallagher AR, Yu Z, Patel V, Igarashi P, Somlo S Journal of the American Society of Nephrology : JASN 2010 Feb 21 2 295-302
Aberrant planar cell polarity induced by urinary tract obstruction.
Li L, Zepeda-Orozco D, Patel V, Truong P, Karner CM, Carroll TJ, Lin F American journal of physiology. Renal physiology 2009 Dec 297 6 F1526-33
Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.
Patel V, Li L, Cobo-Stark P, Shao X, Somlo S, Lin F, Igarashi P Human molecular genetics 2008 Jun 17 11 1578-90
Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.
Brzóska HL, d'Esposito AM, Kolatsi-Joannou M, Patel V, Igarashi P, Lei Y, Finnell RH, Lythgoe MF, Woolf AS, Papakrivopoulou E, Long DA Kidney international 2016 Dec 90 6 1274-1284
MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease.
Lakhia R, Hajarnis S, Williams D, Aboudehen K, Yheskel M, Xing C, Hatley ME, Torres VE, Wallace DP, Patel V Journal of the American Society of Nephrology : JASN 2016 Aug 27 8 2319-30
miR-17~92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease.
Patel V, Williams D, Hajarnis S, Hunter R, Pontoglio M, Somlo S, Igarashi P Proceedings of the National Academy of Sciences of the United States of America 2013 Jun
Primary cilia regulate mTORC1 activity and cell size through Lkb1.
Boehlke C, Kotsis F, Patel V, Braeg S, Voelker H, Bredt S, Beyer T, Janusch H, Hamann C, Gödel M, Müller K, Herbst M, Hornung M, Doerken M, Köttgen M, Nitschke R, Igarashi P, Walz G, Kuehn EW Nature cell biology 2010 Nov 12 11 1115-22
Transcription Factor Hepatocyte Nuclear Factor-1ß Regulates Renal Cholesterol Metabolism.
Aboudehen K, Kim MS, Mitsche M, Garland K, Anderson N, Noureddine L, Pontoglio M, Patel V, Xie Y, DeBose-Boyd R, Igarashi P Journal of the American Society of Nephrology : JASN 2015 Dec
MicroRNAs and fibrosis.
Patel V, Noureddine L Current opinion in nephrology and hypertension 2012 Jul 21 4 410-6
MicroRNAs regulate renal tubule maturation through modulation of Pkd1.
Patel V, Hajarnis S, Williams D, Hunter R, Huynh D, Igarashi P Journal of the American Society of Nephrology : JASN 2012 Dec 23 12 1941-8
Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
Baba M, Furihata M, Hong SB, Tessarollo L, Haines DC, Southon E, Patel V, Igarashi P, Alvord WG, Leighty R, Yao M, Bernardo M, Ileva L, Choyke P, Warren MB, Zbar B, Linehan WM, Schmidt LS Journal of the National Cancer Institute 2008 Jan 100 2 140-54
Mutations of HNF-1beta inhibit epithelial morphogenesis through dysregulation of SOCS-3.
Ma Z, Gong Y, Patel V, Karner CM, Fischer E, Hiesberger T, Carroll TJ, Pontoglio M, Igarashi P Proceedings of the National Academy of Sciences of the United States of America 2007 Dec 104 51 20386-91
Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease.
Lee EC, Valencia T, Allerson C, Schairer A, Flaten A, Yheskel M, Kersjes K, Li J, Gatto S, Takhar M, Lockton S, Pavlicek A, Kim M, Chu T, Soriano R, Davis S, Androsavich JR, Sarwary S, Owen T, Kaplan J, Liu K, Jang G, Neben S, Bentley P, Wright T, Patel V, Nature communications 2019 Sep 10 1 4148
Anti-microRNA screen uncovers miR-17 family within miR-17~92 cluster as the primary driver of kidney cyst growth.
Yheskel M, Lakhia R, Cobo-Stark P, Flaten A, Patel V Scientific reports 2019 Feb 9 1 1920
- Advances in the pathogenesis and treatment of polycystic kidney disease.
- Polycystic Kidney Disease
- Kidney Development and Homeostasis